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541
Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer
Published 2017-04-01“…Long non-coding RNA microarray was applied to investigate the global long non-coding RNA expression profile in colorectal cancer. …”
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542
Global Trends and Emerging Frontiers on Ovarian Endometriosis: A Bibliometric and Visualization Analysis
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543
ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a
Published 2020-07-01“…However, little is known about the genes associated with pancreatitis severity. Our microarray analysis of pancreatic tissues from mild and severe acute pancreatitis mice models identified angiopoietin‐like 4 (ANGPTL4) as one of the most significantly upregulated genes. …”
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544
Reclassification of Variants Following Renal Genetics Testing: Uncommon Yet Impactful for Diagnosis and Management
Published 2024-05-01“…Twenty amendments were issued across 19 pedigrees involving 19 variants in 17 genes. …”
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545
Infiltration of CD3+ and CD8+ lymphocytes in association with inflammation and survival in pancreatic cancer.
Published 2024-01-01“…We aimed to quantitatively assess infiltrating CD3+ and CD8+ lymphocytes in a treatment-naïve patient cohort and assess associations with overall survival and microenvironment inflammatory proteins.<h4>Methods</h4>Tissue microarrays were immunohistochemically stained for CD3+ and CD8+ lymphocytes and quantitatively assessed using QuPath. …”
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546
Expression, clinical significance and biological function of CDC7 in osteosarcoma
Published 2025-02-01“…Objective To investigate the expression and clinical significance of cell division cycle 7 (CDC7) in osteosarcoma (OS) and its effect on the proliferation, migration and invasion of OS cells. Methods The mRNA microarray data from the Gene Expression Omnibus (GEO) database was used to analyze the expression of CDC7 in OS tissues. …”
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547
Identifying shared hub genes in LIRI and MASLD through bioinformatics analysis and machine learning
Published 2025-05-01“…Using liver transplantation and MASLD datasets from the Gene Expression Omnibus, we applied Linear Models for Microarray Data and weighted gene co-expression analysis to identify differentially expressed genes and key module genes. …”
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548
Pericytes in castration-resistant prostate cancer associated with disease progression and immunotherapy response: insights from single-cell analysis
Published 2025-06-01“…The clinical and prognostic significance of CRPC-pericytes was assessed by employing several bulk RNA-seq and microarray datasets. Additionally, we examined the association between the abundance of CRPC-pericytes and immunological features in the PCa microenvironment. …”
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549
Identification of differentially expressed immune-related genes in patients with systemic lupus erythematosus and the development of a hub gene-based diagnostic model
Published 2025-07-01“…Methods This study analyzed gene expression data from three GEO microarray datasets to explore immunity-related differentially expressed genes (DEGs) in SLE. …”
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550
Genome-Wide Association Study of Exercise Addiction Among Elite Wrestlers
Published 2025-01-01“…Whole-genome genotyping was performed using DNA microarray. Results: Using a genome-wide approach (<i>p</i> < 1.0 × 10<sup>−</sup>⁵), we identified six suggestively significant single-nucleotide polymorphisms (SNPs) associated with exercise addiction status. …”
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551
A practical distribution pattern of α-SMA-positive carcinoma associated fibroblasts indicates poor prognosis of patients with pancreatic ductal adenocarcinoma
Published 2025-02-01“…We used tumor specimens to screen out the most suitable markers for the spatial distribution analysis for CAFs subpopulations. We utilized a tissue microarray to assess the spatial intensity of α-SMA expression within the tumor microenvironment. …”
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552
Identification and Cross-Platform Validation of Sparse Molecular Classifiers for Antibody-Mediated and T-Cell–Mediated Rejection After Kidney Transplantation
Published 2025-06-01“…Herein, we aimed to develop and validate sparse molecular classifiers for ABMR and TCMR using allograft tissue. Methods: In a discovery cohort of 224 kidney transplant biopsies, lasso regression was applied on microarray gene expression data to derive a molecular classifier for ABMR and TCMR, respectively. …”
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553
Kinomic profiling to predict sunitinib response of patients with metastasized clear cell Renal Cell Carcinoma
Published 2025-02-01“…Phosphotyrosine-activity profiling was performed using PamChip® peptide microarrays (144 peptides derived from known phosphorylation sites in Protein Tyrosine Kinase substrates) of lysed tissue samples (5 µg protein input) of 163 mRCC patients. …”
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554
QKI-induced circ_0001766 inhibits colorectal cancer progression and rapamycin resistance by miR-1203/PPP1R3C/mTOR/Myc axis
Published 2025-04-01“…Here, we identified and characterized a circular RNA, circ_0001766 (hsa_circ_0001766), through microarray analysis of CRC tissues. Our results showed that circ_0001766 is downregulated in CRC tissues and closely associated with patient survival and metastasis. …”
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555
Improved real-time RT-PCR method for high-throughput measurements using second derivative calculation and double correction
Published 2005-02-01“…Quantification of mRNA expression levels using real-time reverse transcription PCR (RT-PCR) is increasingly used to validate results of DNA microarrays or GeneChips®. It requires an improved method that is more robust and more suitable for high-throughput measurements. …”
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556
Integrated analysis of genomic and transcriptomic profiles identified a prognostic immunohistochemistry panel for esophageal squamous cell cancer
Published 2020-01-01“…Methods An integrated analysis was performed to screen and establish a prognostic panel using exome sequencing profile from 81 pairs of ESCC samples and RNA expression microarray data from 119 ESCC subjects. Two independent ESCC cohorts were recruited as training and validation groups to test the prognostic value. …”
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557
Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma.
Published 2011-04-01“…Immunohistochemical analysis of SCCA expression was performed on tissue microarrays containing breast tumor tissues (n = 1,360) and normal breast epithelium (n = 124). …”
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558
Bioinformatics-driven identification of key non-invasive prognostic biomarkers in hepatocellular carcinoma
Published 2025-04-01“…Methods Publicly available microarray data within the Gene Expression Omnibus repository were analysed to determine genetic elements that were differentially expressed. …”
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559
Siglec-9+ tumor-associated macrophages delineate an immunosuppressive subset with therapeutic vulnerability in patients with high-grade serous ovarian cancer
Published 2023-09-01“…This study aimed to elucidate the prognostic significance of Siglec-9 expression and its predictive value for immunotherapy in HGSC.Methods Study enrolled two cohorts, consisting of 120 tumor microarray specimens of HGSC for immunohistochemistry (IHC) and 40 fresh tumor specimens for flow cytometry (FCM). …”
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560
Inhibition of ATG5-mediated autophagy maintains PMAIP1 stability to promote cell apoptosis and suppress triple-negative breast cancer progression
Published 2025-05-01“…Methods TNBC-related datasets were retrieved from The Cancer Genome Atlas and selected by Prediction Analysis of Microarray 50 analysis to assess the expression of PMAIP1 in the samples. …”
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