-
221
Identification of Novel Molecular Panel as Potential Biomarkers of PAN-Gastrointestinal Cancer Screening: Bioinformatics and Experimental Analysis
Published 2025-07-01“…In the present study, using integrated transcriptomics, RNA-Seq and microarray data, from the TCGA and GEO databases, respectively, were combined to discover and validate a global biomarker panel for PAN-gastrointestinal cancers. …”
Get full text
Article -
222
HDAC1 Mediates Immunosuppression of the Tumor Microenvironment in Non-Small Cell Lung Cancer
Published 2025-03-01“…However, there are no studies on the immunological aspects of HDAC1 in non-small cell lung cancer (NSCLC).Methods: In this research, we used the Cancer Genome Atlas (TCGA) public database combined with tissue microarray (TMA) to investigate HDAC1 expression and prognosis in NSCLC. …”
Get full text
Article -
223
Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.
Published 2008-10-01“…We conclude that Bptf likely regulates genes and signaling pathways essential for the development of key tissues of the early mouse embryo.…”
Get full text
Article -
224
Neighbourhood continuity is not required for correct testis gene expression in Drosophila.
Published 2010-11-01“…We compare gene expression in individuals carrying inverted chromosomes with their non-inverted but otherwise identical progenitors using whole-transcriptome microarray analysis, validating these data with specific quantitative real-time PCR assays. …”
Get full text
Article -
225
-
226
Profiling of gastric cancer cell-surface markers to achieve tumour–normal discrimination
Published 2020-12-01“…Promising candidates from this analysis were validated orthogonally using multispectral immunohistochemistry (mIHC) with automated quantitative analysis using the Vectra platform. mIHC was performed on a tissue microarray containing matched normal, marginal and tumour tissues. …”
Get full text
Article -
227
Next-generation sequencing for endocrine cancers: Recent advances and challenges
Published 2017-04-01“…Endocrine cancers pose a major challenge in health care and research despite considerable attempts by researchers to understand their etiology. Microarray analyses have provided gene signatures from many cells, tissues, and organs that can differentiate healthy states from diseased ones, and even show patterns that correlate with stages of a disease. …”
Get full text
Article -
228
RETRACTED ARTICLE: Multi-stage biomedical feature selection extraction algorithm for cancer detection
Published 2023-04-01“…Early cancer detection is greatly aided by machine learning and artificial intelligence (AI) to gene microarray data sets (microarray data). Despite this, there is a significant discrepancy between the number of gene features in the microarray data set and the number of samples. …”
Get full text
Article -
229
Role of MSX1 in Osteogenic Differentiation of Human Dental Pulp Stem Cells
Published 2016-01-01“…Interestingly, DNA microarray and PCR analyses revealed that MSX1 knockdown induced the sterol regulatory element-binding protein 2 (SREBP2) transcriptional factor and its downstream target genes in the cholesterol synthesis pathway. …”
Get full text
Article -
230
Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression.
Published 2017-01-01“…Tissue angiogenesis is intimately regulated during embryogenesis and postnatal development. …”
Get full text
Article -
231
Brain gliomas new transcriptomic discoveries from differentially expressed genes to therapeutic targets
Published 2025-01-01“…This study aimed to identify new genetic targets linked to glioma by analyzing microarray datasets to uncover genetic factors involved in its onset and progression. …”
Get full text
Article -
232
Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients.
Published 2013-01-01“…Multiple statistical analyses of microarray data suggested that certain exosomal miRNAs were differentially expressed in SZ and BD subjects in comparison to controls. …”
Get full text
Article -
233
Inferring pathway activity toward precise disease classification.
Published 2008-11-01“…The advent of microarray technology has made it possible to classify disease states based on gene expression profiles of patients. …”
Get full text
Article -
234
miR-361-5p contributes to the pathogenesis of Alzheimer’s disease
Published 2025-08-01“…This study investigated the roles of HOMER1, ATAD1, and miR-361 in AD pathogenesis using microarray (GSE106241, GSE157239; n = 60) and RT-PCR (n = 100; 50 AD patients, 50 controls from Northwest Iran) analyses. …”
Get full text
Article -
235
Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation.
Published 2014-01-01“…Conditional knockout of the Miz1 POZ domain in luminal cells during pregnancy caused a lactation defect with a transient reduction of glandular tissue, reduced proliferation and attenuated differentiation. …”
Get full text
Article -
236
Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver
Published 2010-01-01“…Several studies have been conducted using PCR analysis and microarray technology to identify possible target genes and here we review the data obtained from various in vivo and in vitro experimental models. …”
Get full text
Article -
237
The Expression Profile of MicroRNAs in Small and Large Abdominal Aortic Aneurysms
Published 2019-01-01“…Methods. Tissue samples of AAA patients and healthy controls were collected, from which miRNA was isolated. …”
Get full text
Article -
238
Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells
Published 2025-05-01“…Methods The surgical specimens of six patients with GCY were included to construct a tissue microarray containing the tumor core region (TCR), cancer-adjacent tissue (CAT), and normal gastric tissue (NGT). …”
Get full text
Article -
239
Association of Structural Maintenance of Chromosome-1A Phosphorylation with Progression of Breast Cancer
Published 2025-01-01“…This study represents the first investigation to test the phosphorylation status and subcellular localization of SMC1A (p-SMC1A) in breast cancer and normal breast tissues. Immunohistochemical (IHC) staining was conducted using previously validated phospho-SMC1A antibodies on a histological section and tissue microarray (TMA) comprising samples from primary, invasive, and metastatic breast cancer and normal breast tissues. …”
Get full text
Article -
240
Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.
Published 2012-01-01“…Four candidates (Decorin, SPARC, Spry-1, Tsukushi) were immunolocalised in human foetal prostate (weeks 14, 16, 19) and expression of Decorin was evaluated on a human prostate cancer tissue microarray. In embryonic and perinatal rats Decorin, Semaphorin6D, SPARC, Spry-1 and Tsukushi were expressed with varying distribution patterns throughout the mesenchyme at E17.5, E19.5, P0.5 and P6.5. …”
Get full text
Article