Transcriptional meta-analysis and immune cell profiles reveal altered neutrophil dynamics in chronic atrial fibrillation by Elijah Stone, Jude Taylor, Amy Li, Craig S. McLachlan

“…We performed a meta-analysis to combine independent microarray and RNA sequencing (RNAseq) datasets for both persistent and permanent AF left atrial tissue. …”
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Promising Noninvasive Cellular Phenotype in Prostate Cancer Cells Knockdown of Matrix Metalloproteinase 9 by Aditi Gupta, Wei Cao, Kavitha Sadashivaiah, Wantao Chen, Abraham Schneider, Meenakshi A. Chellaiah

“…Immunostaining of prostate tissue microarray sections illustrated significantly lower levels of CD44v6 in adenocarcinoma than normal tissue. …”
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MFAP4 as a novel biomarker for predicting liver fibrosis and prognosis in infants with biliary atresia through the integration of bioinformatics with clinical data analysis by Chunxiao Yang, Chunxiao Yang, Jianghua Zhan, Jianghua Zhan

“…Clinical BA liver tissue samples were collected for quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and western blotting (WB). …”
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Transcriptional regulation by CHIP/LDB complexes. by Revital Bronstein, Liron Levkovitz, Nir Yosef, Michaela Yanku, Eytan Ruppin, Roded Sharan, Heiner Westphal, Brian Oliver, Daniel Segal

“…Here we use the powerful genetics of Drosophila combined with microarray and bioinformatics analyses to tackle this challenge. …”
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A Comparative Study of Mouse Hepatic and Intestinal Gene Expression Profiles under PPARα Knockout by Gene Set Enrichment... by Kan He, Qishan Wang, Yumei Yang, Minghui Wang, Yuchun Pan

“…We also provided some novel hepatic tissue-specific marker genes.…”
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Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing by Ye Jin Ha, Seong-Hwan Park, Seon-Kyu Kim, Ka Hee Tak, Jeong-Hwan Kim, Chan Wook Kim, Yong Sik Yoon, Seon-Young Kim, Jong Lyul Lee

“…We also offer protein expression data from a tissue microarray (TMA) analysis of 90 samples (45 PMPs). …”
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Targeting insulin-like growth factor 1 receptor restricts development and severity of secondary lymphedema in mice by Yinan Yuan, Sidney M. Levy, Yong Qiang Yeo, Ramin Shayan, Tara Karnezis, Steven A. Stacker, Marc G. Achen

“…Here, using a surgical mouse model of secondary lymphedema and whole-genome microarray, we identified the transcript for insulin-like growth factor binding protein 5 (IGFBP5), a negative regulator of insulin-like growth factor (IGF) signaling, as the most profoundly down-regulated in lymphedematous tissue. …”
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Bioinformatics identification of key genes associated with the prognosis of gastric cancer by LIU Zhao, LIU Rui, FAN Haijing, SUN Hui, LYU Jing, ZHANG Zhen

“…Objective To screen and identify key genes and pathways associated with the prognosis of gastric cancer, and to investigate the mechanisms of the development and progression of gastric cancer. Methods Microarray datasets (GSE2685, GSE29272) of gastric cancer gene expression profile were downloaded from the gene expression omnibus, and the online analytical tool GEO2R was used to screen for differentially expressed genes (DEGs) between gastric cancer tissue and normal tissue. …”
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Exosomal miR-93-3p targets EIF4EBP1 to regulate macrophage polarization and accelerate wound healing post-anal fistula surgery by Wei Zhang, Wenzhe Feng, Junhong Chen, Ruoxi Cao, Xi Chen

“…Total RNA was extracted through the TRIzol method, followed by miRNA microarray analysis to identify differentially expressed miRNAs (DEMs). …”
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Expression and correlation of Surfeit 4 gene in esophageal squamous cell carcinoma by Jun-xing Liu, Ting Lu, Yin Xia, Jun Yang, Ying-feng Jiang, Yan Zhao, Hong Yu

“…The results of the three methods indicated a significantly higher expression of SURF4 in the tumor group compared to both the adjacent paracancerous tissue group and the normal esophageal mucosal tissue group distant from the tumor. …”
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Identification of a Novel 15q21.1 Microdeletion in a Family with Marfan Syndrome by Rencong Yang, Wu Zhang, Hua Lu, Jinlong Liu, Yu Xia, Shengjie Liao, Xiaohui Li, Xiaoshen Zhang, Xiaoping Fan, Chaojie Wang

“…Marfan syndrome (MFS) is a connective tissue disease involving multiple systems, with thoracic aortic aneurysm (TAA) as the most common life-threatening manifestation. …”
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Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma. by Ananya Roy, Julia Femel, Elisabeth J M Huijbers, Dorothe Spillmann, Erik Larsson, Maria Ringvall, Anna-Karin Olsson, Magnus Åbrink

“…Although E-cadherin expression was higher in the serglycin-deficient primary tumour tissue, indicating reduced invasiveness, serglycin-deficient tumour cells were still detected in the circulation. …”
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ADP-ribosylation factor 6 expression increase in oesophageal adenocarcinoma suggests a potential biomarker role for it. by Venkateswarlu Kanamarlapudi, Salman Tamaddon-Jahromi, Kate Murphy

“…We further evaluated ARF6 protein expression in oesophageal adenocarcinoma (EAC) tissue microarray cores by immunohistochemistry. The ARF6 gene expression levels are highly variable between healthy and cancer tissues. …”
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Exploring the Functional Disorder and Corresponding Key Transcription Factors in Intraductal Papillary Mucinous Neoplasms Progression by Guiying Bai, Chenxuan Wu, Yingtang Gao, Guiming Shu

“…This study has analyzed the gene expression patterns of an IPMN microarray dataset including normal pancreatic ductal tissue (NT), intraductal papillary mucinous adenoma (IPMA), intraductal papillary mucinous carcinoma (IPMC), and invasive ductal carcinoma (IDC) samples. …”
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Automated cell annotation and classification on histopathology for spatial biomarker discovery by Zhe Li, Seyed Hossein Mirjahanmardi, Rasoul Sali, Feyisope Eweje, Matthew Gopaulchan, Leon Kloker, Xiaoming Zhang, Guoxin Li, Yuming Jiang, Ruijiang Li

“…By co-registering H&E images with mIF of the same tissue section at the single-cell level, we create a dataset of 1,127,252 cells with high-quality annotations on tissue microarray cores. …”
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The impact of MITF expression on tumor-infiltrating lymphocytes in melanoma: Insights into immune microenvironment dynamics by Damir Vučinić, Matea Lekić, Gordana Žauhar, Gordana Zamolo

“…Archival formalin-fixed, paraffin-embedded tissue samples from 81 primary melanoma patients were analyzed via tissue microarray immunohistochemistry to assess MITF protein levels. …”
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Differential BACH1 Expression in Basal-like Breast Tumors of Black Women Identified via Immunohistochemistry by N. M. Dowling, Galina Khramtsova, Olufunmilayo Olopade, Shabnam Samankan, Bok-Soon Lee, Jiyoung Lee

“…However, the clinical relevance of BACH1 expression in breast tumors remains poorly understood. Using a tissue microarray from a cohort of 130 patients, we assessed the expression of BACH1 and its known target gene, MCT1 (encoded by <i>SLC16A1</i>), through immunohistochemistry (IHC). …”
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Exploring the immune microenvironment in small bowel adenocarcinoma using digital image analysis. by Fatima Abdullahi Sidi, Victoria Bingham, Stephen McQuaid, Stephanie G Craig, Richard C Turkington, Jacqueline A James, Matthew P Humphries, Manuel Salto-Tellez

“…<h4>Methods</h4>25 patient samples in the form of formalin fixed, paraffin embedded (FFPE) tissue were obtained in tissue microarray (TMAs) format. …”
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Immunohistochemical study of histone protein 3 modification in pediatric osteosarcoma identifies reduced H3K27me3 as a marker of poor treatment response. by Sebastian Kondratowski, Danielle Cohen, Rebecca J Deyell, Ash Sandhu, Jonathan W Bush

“…We aimed to characterize the methylation and phosphorylation status in osteosarcoma using histone markers found in primary diagnostic biopsies and their paired metastases. We constructed two tissue microarray sets from 58 primary diagnostic samples and 54 temporally-separated but related metastatic or recurrent samples, with tissue blocks available from 2002-2022. …”
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TIM‐4 increases the proportion of CD4+CD25+FOXP3+ regulatory T cells in the pancreatic ductal adenocarcinoma microenvironment by inhibiting IL‐6 secretion by Ziyao Wang, Zerong Xie, Yu Mou, Ruiman Geng, Chen Chen, Nengwen Ke

“…Meanwhile, multiple fluorescent immunohistochemical staining was used to study the distribution characteristics of TIM‐4, and through tissue microarrays, we explored its correlation with patient prognosis. …”
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