Label‐Free 3D Photoacoustic Imaging of Tumor Organoids for Volumetric Drug Screening by Xiaofei Luo, Maike Chen, Han Shan, Xize Yu, Qibo Lin, Qian Tao, Xiongwei Wei, Changling Lv, Ziyan Chen, Fan Zhuo, Xi Zhu, Jiaxing He, Zhaoxi Li, Chunlong Fei, Jing Xu, Juan Su, Zeyu Chen, Shuang Zhao, Xiang Chen

“…The capabilities of the LFOPI system are evaluated by monitoring structural transformations in melanoma organoids. The LFOPI system is further employed for volumetric drug screening of melanoma tumor organoids. …”
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Uncovering the genetic architecture of inherited retinal disease in a consanguineous Iranian cohort by Lieselot Vincke, Kristof Van Schil, Hamid Ahmadieh, Afrooz Moghaddasi, Hamideh Sabbaghi, Narsis Daftarian, Tahmineh Motevasseli, Leila Javanparast Sheykhani, Mohammadreza Dehghani, Mohammad Yahya Vahidi Mehrjardi, Julie De Zaeytijd, Marieke De Bruyne, Quinten Mahieu, Ebrahim Al-Hajj, Marta Del Pozo-Valero, Toon Rosseel, Mattias Van Heetvelde, Reza Maroofian, Fatemeh Suri, Miriam Bauwens, Elfride De Baere

“…Variants in ROHs were found in 82.8% of patients from consanguineous backgrounds. The importance of structural variation (SV) was demonstrated, with CNVs identified in 5.3%, including several novel CNVs. …”
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Electron microscopic changes in the nasal membrane of patients with COVID-19 depending on the clinical form and the period of the disease by E. V. Kryukov, K. V. Zhdanov, K. V. Kozlov, V. Yu. Kravtsov, O. V. Mal’tsev, V. S. Sukachev, P. I. Miklush, M. O. Sokolova, V. V. Sharabkhanov, R. I. Glushakov, V. V. Dvoryanchikov, R. R. Achba, D. V. Trishkin, I. I. Azarov

“…Understanding the ultra-structural cell changes of SARS-CoV-2 targets may help clarify the pathogenic aspects of infection in the lower respiratory tract. …”
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Magnetic Resonance Imaging Lesions Associated With Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury by Jamie E. Podell, Eric W. Moffet, Uttam K. Bodanapally, Mehrnaz Pajoumand, Luisa M. Silva, Peter Hu, Lujie K. Chen, Nicholas A. Morris, Gunjan Parikh, Gary T. Schwartzbauer, Bizhan Aarabi, Neeraj Badjatia

“…This exploratory study supports the hypothesis that structural damage to CAN regions is associated with the clinical syndrome of PSH after TBI, and provides foundational evidence for future data-driven studies.…”
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Targeting the IL-17A pathway for therapy in early-stage tendinopathy by Iain B McInnes, Richard M Siegel, Neal L Millar, Moeed Akbar, Michaela Kneissel, Frank Kolbinger, Friedrich Raulf, Yufei Li, Nicolau Beckmann, Nathalie Accart, Olivier Leupin, Claudio Calonder, Matthias Schieker, Christian Bruns, Eckhard Weber

“…In the rat ex vivo and in vivo models, IL-17A blockade alleviated inflammatory immune effector release, tendon structural degeneration, tendon inflammation and impaired tendon function.Conclusion Our data provide evidence that IL-17A is a key contributor to the pathogenesis of tendinopathy by promoting tendon inflammation and degeneration and that IL-17A blockade may represent a potential therapy in early-stage tendinopathy.…”
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Longitudinal study of COPD phenotypes using integrated SPECT and qCT imaging by Frank Li, Frank Li, Xuan Zhang, Xuan Zhang, Alejandro P. Comellas, Eric A. Hoffman, Eric A. Hoffman, Michael M. Graham, Ching-Long Lin, Ching-Long Lin, Ching-Long Lin, Ching-Long Lin

“…This approach seeks to enhance our understanding of how structural and functional changes influence ventilation heterogeneity in COPD.MethodsEight COPD subjects completed a longitudinal study with three visits, spaced about a year apart. …”
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Petrology and mineral chemistry of the Hamaneh granitoid, West of Yazd (Central Iran zone) by Javad Ghanei Ardakani, Maryam Ahankoub

“…The parent magma of the rocks under study belongs to the subduction structural ground position related to the active continental margin.…”
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Phenomenological Exploration of Organ Donor Families’ Experiences: From Decision-Making to the Consequences of Life Donation by Yazdan Karimi Monjarmooei, SeyedAlireza Afshani, Ali Ruhani, Mohammad Mobaraki, Ahmad Kalateh Sadati

“…This sampling approach ensured the inclusion of information-rich cases aligned with the research objectives. Data were collected through in-depth, semi-structured interviews. …”
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HyperCell: A Bio-inspired Design Framework for Real-time Interactive Architectures by Jia-Rey Chang

“…A holistic bio-inspired architecture embodies multiple performance criteria akin to natural systems, which integrate structural, infrastructure performances throughout the growth of an organic body. …”
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Multi-sphere coupling characteristics and gas-bearing controlling factors of calcareous shale reservoirs in the Yadu-Ziyun-Luodian Aulacogen under Early Carboniferous platform-basi... by Kun Yuan, Kun Yuan, Kun Yuan, Bing Feng, Gangquan Li, Zongan Xue, Zongan Xue, Zongan Xue, Tuo Lin, Tuo Lin, Tuo Lin, Xinxin Fang, Xiangcan Sun, Xiangcan Sun, Xiangcan Sun, Yinbo Xu, Yinbo Xu, Yinbo Xu, Fengzan Zheng

“…Integrating field geological surveys and well data, this study comprehensively evaluates the mineralogy, geochemistry, structural features, and gas content of these shales to decipher the key factors controlling gas enrichment, particularly in this tectonically complex area. …”
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Intelligent Automated Monitoring and Curing System for Cracks in Concrete Elements Using Integrated Sensors and Embedded Controllers by Papa Pio Ascona García, Guido Elar Ordoñez Carpio, Wilmer Moisés Zelada Zamora, Marco Antonio Aguirre Camacho, Wilmer Rojas Pintado, Emerson Julio Cuadros Rojas, Hipatia Merlita Mundaca Ramos, Nilthon Arce Fernández

“…This study addresses the formation, detection, and repair of cracks in concrete elements exposed to temperatures above 25 °C, where accelerated evaporation compromises their structural strength. An automated intelligent curing system with embedded sensors (DS18B20, HD-38) and Arduino controllers was developed and applied to solid slabs, columns, and concrete test specimens (1:2:3.5 mix ratio). …”
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Emerging roles of the cancerous inhibitor of protein phosphatase 2A (CIP2A) in ovarian cancer by Alice Filipe, Sayeh Saravi, Denis Mustafov, Suzana Panfilov, Simran Banger, Seyedehnajmeh Mousavikivaj, Maria Braoudaki, Senthilkumar Kailasam, Yasser Riazalhosseini, Michelle A. Sahai, Fotios Drenos, Cristina Sisu, Emmanouil Karteris

“…High CIP2A expression reduces both overall-and progression-free survival, whereas an R530T mutation is predicted to cause structural destabilisation of the CIP2A dimer. We also provide evidence for microRNA (miRNA) and mRNA target interactions with CIP2A. …”
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Do women with a history of breast cancer recommend risk-based breast cancer screening? An in-depth interview study by Zi Lin Lim, Freda Giam, Renee Ying Xuan Wong, Jonathan Jun Kit Liow, Keri McCrickerd, Keri McCrickerd, Jingmei Li, Jingmei Li, Jingmei Li

“…This study explores women’s perceptions of the facilitators and barriers to current screening guidelines and the implementation of risk-based screening (RBS) for breast cancer in Singapore.MethodsIndividual semi-structured interviews were conducted with 11 women aged 21 and above with a history of breast cancer. …”
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Integrating multi-model frameworks to unravel the spatiotemporal dynamics of flash floods in the Tianshan Mountain, China by Biao Zhang, Haiyan Fang, Guotao Zhang, Songqing Li, Shufang Wu, Kadambot H.M. Siddique

“…Subsequently, the Partial Least Squares Structural Equation (PLS-SEM) was used to explore the direct and indirect influence pathways among driving factors. …”
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Exploring the sequential mediation model of coping humor, self-esteem, resilience, and subjective well-being among Taiwanese university students by Chin-Wen Liao, Chih-Yu Ting, Yao-Chung Cheng, Kai-Jie Chen, An-Sheng Liu, Tzu-Ju Hsueh

“…Analyses were conducted using IBM SPSS 27.0 and SmartPLS 4.0, applying descriptive statistics, Pearson correlation, t-tests, ANOVA, and Partial Least Squares Structural Equation Modeling (PLS-SEM). Results confirmed that self-esteem and resilience significantly mediate the relationship between coping humor and subjective happiness, validating the proposed model. …”
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Pitik: A Cebuano-Binisaya Intent-Based Chatbot for Cardiovascular Disease Patient Profiling and Risk Factor Recommendations by Joseph Cedeño, Andrew Manteza, Nicole Nacar, Merhamdin Umbukan, Cherrie Muaña, Ma. Juliet Vasay-Cruz, Ceasar Ian Benablo, Kristine Mae Adlaon

“…To address this, Pitik, a Cebuano-Binisaya intent-based chatbot, was developed to streamline cardiovascular risk profiling and data collection, particularly in underserved areas. …”
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A Neuropsychological Rehabilitation Program for Cognitive Impairment in Psychiatric and Neurological Conditions: A Review That Supports Its Efficacy by Ainara Gómez-Gastiasoro, Javier Peña, Naroa Ibarretxe-Bilbao, Olaia Lucas-Jiménez, María Díez-Cirarda, Oiane Rilo, Genoveva Montoya-Murillo, Leire Zubiaurre-Elorza, Natalia Ojeda

“…This manuscript presents the efficacy data of REHACOP across these three populations and discusses it in the context of the available literature. …”
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Sustainable transformation of cotton stalk waste as a biochar-based copper-silicon composite for chromium (VI) detoxification by Sana Shakil, Salah Ud Din, Khawaja Ansar Yasin, Muhammad Sheraz Ahmad, Muhammad Imran, Abdurahman Hajinur Hirad, Jamoliddin Razzokov, Sirajul Haq

“…Characterization techniques, including XRD, FTIR, EDX, SEM, TEM, XPS, and PZC analysis, confirmed the material's structural and chemical properties. Peaks at 153 eV (Si2p) and 932.1 eV (Cu 2p) validated the presence of silicon and copper, while a peak at 529.9 eV indicated Cr₂O₃/Cr(OH)₃ formation after adsorption. …”
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Numerical Simulation of Thermal Fields and Microstructure Evolution in SLM of Fe₃₂Cr₃₃Ni₂₉Al₃Ti₃ Alloy by Xuyun Peng, Xiaojun Tan, Haibing Xiao, Wei Zhang, Liang Guo, Wei Tan, Jian Huang, Chaojun Ding, Yushan Yang, Jieshun Yang, Haitao Chen, Qingmao Zhang

“…Fabricating eutectic high-entropy alloys (EHEAs) via selective laser melting (SLM) presents significant potential for advanced structural applications. This study explores the microstructural evolution of Fe₃₂Cr₃₃Ni₂₉Al₃Ti₃ EHEAs fabricated by SLM under varying laser powers. …”
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School physical education and health based on the principles of body literacy: propositions and validation of an educational technology by Evelyne Ferreira de Castro, Magna Leilane da Silva, Allana Kelly Cerqueira Lima Carvalho, Patrícia Ribeiro Feitosa Lima, José Airton Pontes Junior, Valter Cordeiro Barbosa Filho

“…The developed ET comprises 17 pages, structured around three topics: School Physical Education as a promoter of health, the concept and principles of BL, and successful practical experiences. …”
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