DAILY – A personalized circadian Zeitgeber therapy as an adjunctive treatment for alcohol use disorder patients: results of a pilot trial by Naomi Springer, Naomi Springer, Lisa Echtler, Lisa Echtler, Paul Volkmann, Anisja Hühne-Landgraf, Anisja Hühne-Landgraf, Jasmin Hochenbleicher, Eva Hoch, Eva Hoch, Gabi Koller, Dominic Landgraf

“…With our newly developed therapy approach for AUD patients, we aim to reduce relapses and alcohol consumption in AUD patients undergoing a withdrawal program by strengthening their circadian rhythms.Methods/DesignWe aim to achieve the improvement of circadian rhythms with personalized structure plans for daily Zeitgeber activities, which are used in parallel with the standard therapy at our clinic. …”
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Aberrant EZHIP expression drives tumorigenesis in osteosarcoma by Wajih Jawhar, Geoffroy Danieau, Alva Annett, Takeaki Ishii, Andrea Bajic, Ana Castillo-Orozco, Brian Krug, Yara Faucher-Jabado, Justin Seyedmoomenkashi, Mostafa Saquib, Masoumeh Aghababazadeh, Marjan Khatami, Nadim Tawil, Damien Faury, Sungmi Jung, Ahmed Aoude, Robert E. Turcotte, Benjamin Ellezam, Thomas Sontag, Sylvie Langlois, Daniel Sinnett, Swneke D. Bailey, Lingxin Zhang, Dorothée Dal Soglio, Claudia L. Kleinman, Nada Jabado, Livia Garzia

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Planning for scale: analysis of adaptations and contextual factors influencing scale-up of the QUALI-DEC intervention to optimize caesarean section use by Soha El-Halabi, Claudia Hanson, Alexandre Dumont, Amanda Cleeve, Helle Mölsted Alvesson, Charles Kaboré, Guillermo Carroli, Pisake Lumbiganon, Quoc Nhu Hung Mac, Ana Pilar Betran, Kristi Sidney Annerstedt, Meghan A. Bohren, Karen Zamboni

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Production and characterization of kombucha-like beverage by cocoa (Theobroma cacao) by-product as raw material by Lívia de Matos Santos, Mariana Nougalli Roselino, Janaína de Carvalho Alves, Suelen Neris Almeida Viana, Elis dos Reis Requião, Jéssica Maria Rio Branco dos Santos Ferro, Carolina Oliveira de Souza, Camila Duarte Ferreira Ribeiro

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Computational screening campaign reveal natural candidates as potential ASK1 inhibitors: Pharmacophore modeling, molecular docking, MMGBSA calculations, ADMET prediction, and molec... by Rayan Yousif, Hagar M. Mohamed, Mohammed A. Almogaddam, Khaled M. Elamin, Sabrin R.M. Ibrahim, Bayan E. Ainousah, Ahmed Mohammad Alraddadi, Ehda Ahmad Awad, Abdulrahim A. Alzain

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Development of the Japanese version of the perceived time poverty scale. by Takeshi Miura, Koji Hara, Azusa Arimoto, Masato Kaneko, Sayuri Shiraishi, Shingo Matsumura, Shuichi Ito, Kentaro Kurasawa, Yohei Matsuzaki, Makoto Kuroki

“…Exploratory factor analysis confirmed a single-factor structure and confirmatory factor analysis supported this structure with fit indexes (CFI =  0.957, TLI =  0.929, RMSEA =  0.136, SRMR =  0.035). …”
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Fu’s subcutaneous needling facilitates muscle repair by regulating mitochondrial homeostasis in rat with chronic peripheral nervous pain by Po-En Chiu, Po-En Chiu, Zhonghua Fu, Zhonghua Fu, Hung-Chuan Pan, Hung-Chuan Pan, Hung-Chuan Pan, Hung-Chuan Pan, Yi-Ching Tsai, Chia-Yun Tsai, Wei-Jen Hsu, Li-Wei Chou, Li-Wei Chou, Li-Wei Chou, De-Wei Lai, De-Wei Lai

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Synthesis, physical-chemical properties, antimicrobial and antifungal activity of some 2-(2-((5-(adamantane-1-yl)-4-R-1,2,4-triazole-3-yl)thio)acetyl)-N-R1–hydrazine-carbothioamide... by V. M. Odyntsova, A. M. Kamyshny, N. N. Polischuk

“…They select natural heterocyclic molecules that exhibit various types of pharmacological activity as basic structures. Adamantane derivatives, as well as a number of other framework compounds, in the vast majority are biologically active substances. …”
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Degradation of low-density polyethylene by a novel strain of bacteria isolated from the plastisphere of marine ecosystems by F.A. Febria, A. Syafrita, A. Putra, H. Hidayat, C. Febrion

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Aortic Aneurysm Inflammatory Cell Detection with Deep Learning methods by Kristóf-Gergö Nagy, Csaba Szferle, Attila Fintha

“…INTRODUCTION: In digital pathology, neural networks such as the Multilayer Perceptron (MLP) and Residual Neural Network (ResNet) are becoming increasingly prevalent for the analysis of tissue structure. However, their application remains constrained. …”
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Association of Concave Deformity of the Anterior Scalene on Magnetic Resonance Imaging with Vascular Variant of Neurogenic Thoracic Outlet Syndrome by Madi El-Haj, MD, MS, Shaul Beyth, MD, Amit Korach, MD, Ori Wald, MD, Tal Eliav, MS, Yosef Kalish, MD, Sofia A. Vorobeitchik, MS, Allan I. Bloom, MD

“…Intraoperatively, all patients had at least one structural anomaly. Preoperative symptoms of lower or middle-lower brachial plexus trunk compressions were more prominent in patients with the vascular variant (B1: 85%, B2: 83%, and B3: 83%) than the pure NTOS (type A) (40%). …”
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The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer by Yuqian Yan, Jian Ma, Dejie Wang, Dong Lin, Xiaodong Pang, Shangqian Wang, Yu Zhao, Lei Shi, Hui Xue, Yunqian Pan, Jun Zhang, Claes Wahlestedt, Francis J Giles, Yu Chen, Martin E Gleave, Collin C Collins, Dingwei Ye, Yuzhuo Wang, Haojie Huang

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SEGS-1 episomes generated during cassava mosaic disease enhance disease severity by Evangelista Chiunga, Evangelista Chiunga, Evangelista Chiunga, Catherine D. Aimone, Cyprian Rajabu, Mary M. Dallas, Joseph Ndunguru, José T. Ascencio-Ibáñez, Elijah M. Ateka, Linda Hanley-Bowdoin

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Predicting leakage of the VERCORS mock-up and concrete containment buildings - a digital twin approach by Laurent Charpin, Jessica Haelewyn, Anass Cherki El Idrissi, Julien Niepceron, Benoît Masson, Charles Toulemonde, Guillaume Boulant, Jean-Philippe Mathieu, François Hamon, Sylvie Michel-Ponnelle, Jean-Marie Hénault, Frédéric Taillade, Jean-Luc Adia, Florian Escoffier

“…An important numerical effort has also been made to implement structural computations of the mock-up and to capitalize these computations as well as their post-processing (so as to compare automatically with the monitoring data) in what can be called a digital twin of the mock-up. …”
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In silico screening of naturally derived dietary compounds as potential butyrylcholinesterase inhibitors for Alzheimer’s disease treatment by Md. Tarikul Islam, Md. Aktaruzzaman, Chandan Barai, Farhan Ishrak Rafi, Al Riyad Hasan, Tasfiah Tasnim, Parvej Sarder, Ghadeer M. Albadrani, Muath Q. Al-Ghadi, Amany A. Sayed, Mohamed M. Abdel-Daim, Humayra Afroz Dona, Kishore Kumar Sarkar, Md. Obayed Raihan

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Adaptive traits of Nitrosocosmicus clade ammonia-oxidizing archaea by Saem Han, Seongwook Kim, Christopher J. Sedlacek, Adeel Farooq, Chihong Song, Sujin Lee, Shurong Liu, Nicolas Brüggemann, Lena Rohe, Miye Kwon, Sung-Keun Rhee, Man-Young Jung

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Neuroimaging and kinematic biomarkers of post-stroke upper limb motor impairment by Joyce L. Chen, Timothy K. Lam, Melanie C. Baniña, Daniele Piscitelli, Mindy F. Levin

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Cardioprotective effects of liposomal resveratrol in diabetic rats: unveiling antioxidant and anti-inflammatory benefits by Ahmed Z. Alanazi, Mohammed Alqinyah, Abdullah S. Alhamed, Hanan Mohammed, Mohammad Raish, Khaldoon Aljerian, Jawza F. Alsabhan, Khalid Alhazzani

“…Notably, LR modulated apoptotic regulators, including caspase, Bcl2, and Bax, suggesting a role in regulating programmed cell death. These biochemical alterations were consistent with improved structural integrity of cardiac tissue as revealed by histological examination. …”
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Transitioning to adult care in youth-onset diabetes: a scoping review of socio-ecological factors in youth-onset type 2 diabetes compared to type 1 diabetes by Assumpta O. Ude, Sydney A. Dixon, Sophia B. Glaros, Sue-Ann Arboine, Nancy L. Terry, Tomás Cabeza De Baca, Stephanie T. Chung

“…Identified challenges associated with the transitioning period in Y-T2D were societal (structural bias, poverty, inadequate social support), health cultural (limited access to adult health-care providers), psychological (feelings of anxiety and fear of transition), and behavioral (difficulty with medication adherence). …”
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Measuring the quality of self-care of elderly patients with dementia in a developing country by Dennis Rogers Buwembo, Joy Louise Gumikiriza-Onoria, Lwere Kamada, Mark Kaddu-Mukasa, Joseph Kagaayi, Juliet Kiguli, Martha Sajatovic, Noeline Nakasujja, Fredrick Makumbi

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