Cancer-associated VEGFR2R1032Q sustains receptor activation also by promoting ligand-independent hetero-dimerization with co-expressed wild-type VEGFR2 and translocation into lipid... by Cosetta Ravelli, Michela Corsini, Roberto Bresciani, Angela M. Rizzo, Luca Zammataro, Paola A. Corsetto, Elisabetta Grillo, Stefania Mitola

“…This was associated with reduced mobility of the receptor on the membrane, linked to its translocation into detergent-resistant membrane (DRM) domains (e.g. lipid rafts), which showed alterations in lipid compositions and structure. These data shed light on a novel oncogenic mechanism of activation of VEGFR2, clarifying the paradoxical loss-of-function nature of the substitution R1032Q of VEGFR2.…”
Get full text

Main factors of primary arterial hypertension development and pathogenesis in young, call-up-aged men with complicated family anamnesis by V. A. Lusov, E. M. Evsikov, Yu. M. Mashukova, T. V. Kotov, N. O. Kugaenko, N. E. Ivakhnenko, T. B. Salova

“…Hemodynamics was assessed by blood pressure (BP) office measurement and ambulatory monitoring, together with B-mode echocardiography data. Renal and renourinal structure and function was assessed by static and dynamic scintigraphy, renal ultrasound, renal radiography, excretory urography, color Doppler angiography of renal arteries, measurement of microalbuminuria in morning urine and glomerular filtration rate by endogenous creatinine. …”
Get full text

Identifying and Prioritizing Creative Tourism Attractions in the Life of the Nomads from the Guest-Host Perspective (Case study: Bakhtiari Tribe, Khuzestan Province) by Mehrnoosh bastenega, Anahita Azarbod

“…The data obtained from the combination of the opinions of the sample members were analyzed using the Shannon entropy technique for evaluating the indicators and TOPSIS for prioritizing the attractions from the host and guest perspectives. …”
Get full text

Experiences of Home‐Based Pulmonary Rehabilitation With mHealth and Centre‐Based Pulmonary Rehabilitation in People With Chronic Obstructive Pulmonary Disease: A Qualitative Study... by Hannah Rutherford, Marita Dale, Sally Wootton, Rashmi Pithavadian, Sarah Dennis, Sarah Brown, Jennifer A. Alison, Andrew S. L. Chan, Ian A. Yang, Zoe McKeough

“…Participants undertook individual, semi‐structured interviews. Interview transcripts were inductively coded and thematically analysed using a critical realist approach. …”
Get full text

New isotopic evidence for micro and mesothermal valleys camelids from Northwest Argentina by Violeta Anahí Killian Galván, Violeta Anahí Killian Galván, Carlos Raúl Belotti López de Medina, Carlos Raúl Belotti López de Medina, María Fabiana Bugliani, María Fabiana Bugliani, María Fabiana Bugliani, Romina Clara Spano

“…Examining pastoral movement techniques, as well as the areas available for wild resource gathering, allows us to acquire a better understanding of the nature and scale of social structure among these human communities. Stable isotope analyses of carbon (13C/12C; δ13C) and nitrogen (15N/14N; δ15N) provide efficient tools for understanding these features.MethodsThe article shows the bone collagen measurements of a sample of camelid bones from archaeofaunas recovered from Soria 2 sites (n = 7) and structure 93 of Loma l'Ántigo (n = 5), all in Catamarca province. …”
Get full text

Oral Surgical Site Infections and Wound Healing Associated with Silk Fibroin Sutures versus Alternative Suture Materials: A Systematic Review by Kranti Kiran Reddy Ealla, Neema Kumari, Ellojita Rout, Vikas Sahu, Vishnu Priya Veeraraghavan, Pratibha Ramani

“…However, their multifilament structure makes them susceptible to higher bacterial adherence. …”
Get full text

Yttrium nitrate activates the oxidative stress-mediated NF-κB pathway to induce testicular inflammatory response and reduce sperm quality in mice by Si-Fan Zhang, Na Li, Dong-Li Liu, Yong-Hong Li, Yi Yang, Yao Ma, Yu-Qing Wang, Yue Ma, Zhao-jin Luan

“…Nevertheless, limited toxicological data are available to determine yttrium's toxicity and potential mechanisms on sperm. …”
Get full text

New evidence of alternative migration patterns for two Mediterranean potamodromous species by Ana Sofia Rato, Carlos M. Alexandre, Sílvia Pedro, Catarina S. Mateus, Esmeralda Pereira, Ana F. Belo, Bernardo R. Quintella, Maria F. Quadrado, Ana Telhado, Carlos Batista, Pedro R. Almeida

“…In the Mondego River basin, at the Coimbra dam, migratory movement patterns and individual size structure were assessed through a video recording monitoring system installed on an upstream section of a vertical-slot fish pass. …”
Get full text

G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo by Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie‐Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W David Wilson, David W Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M Isaacs

“…GGGGCC repeat RNA folds into a G‐quadruplex secondary structure, and we investigated whether targeting this structure is a potential therapeutic strategy. …”
Get full text

The Longitudinal Effect of Psychological Distress on Internet Addiction Symptoms Among Chinese College Students: Cross-Lagged Panel Network Analysis by Yuxuan Jiang, Chuman Xiao, Xiang Wang, Dongling Yuan, Qian Liu, Yan Han, Jie Fan, Xiongzhao Zhu

“…ResultsThe cross-sectional networks of IA symptoms at 3 time points showed high similarity in terms of structure, existence of edges, and centrality indices. …”
Get full text

Characteristics and dynamics of cognitive impairment in patients with primary and recurrent cerebral ischemic hemispheric stroke by A. A. Kozyolkin, А. А. Kuznietsov, L. V. Novikova

“…Acute cerebrovascular disease is a global medical and social problem of the modern angioneurology, occupying leading positions in the structure of morbidity and mortality among adult population of the world. …”
Get full text

Analysis of Soil Fungal Community Characteristics of <i>Morchella sextelata</i> Under Different Rotations and Intercropping Patterns and Influencing Factors by Weilin Feng, Jiawen Wang, Qunli Jin, Zier Guo, Weiming Cai

“…Our results indicate that <i>Morchella</i> spp. cultivation leads to a significant decline in soil fungal diversity compared to uncultivated soils This indicates that cultivation with <i>Morchella</i> spp. simplifies the soil fungal community structure to some extent. Furthermore, distinct variations in fungal community structure were observed across the different cropping systems. …”
Get full text

Disorders of sex development 45,X/46,XY: clinical and laboratory characteristics of patients by Oleg Yu. Latyshev, Ekaterina S. Sannikova, Lubov N. Samsonova, Elena V. Kiseleva, Goar F. Okminyan, Olga M. Dondup, Elvira P. Kasatkina

“…A group of patients with DSD 45,X/46,XY is heterogenous in the degree of gonadal dysgenesis, the structure of the external and internal genitalia.…”
Get full text

Sustainable management and responsible practices in SMEs: A comparative study of certified and non-certified Algerian SMEs by Mohammed Daoudi, Salah Eddine Mendli

“…The study reinforces the view that structured sustainability models, such as ISO certifications, are essential for SMEs to align with global environmental and social expectations. …”
Get full text

Light source classification and colour change modelling for understanding and predicting pigments discolouration by Panagiotis Siozos, Letizia Monico, Aldo Romani, Costanza Miliani, Brenda Doherty, Irina Crina Anca Sandu, Hartmut Kutzke, Ingrid M T Flåte, Petros Stavroulakis, Sophia Sotiropoulou

Get full text

The Effect of Landscape Pattern on Urban Temperature Changes in Hamadan by Marziye Shojaei, Kamran Shayesteh, Behnaz Attaeian

“…Therefore, understanding the spatial distribution of landscape structure in complex patchwork mosaics has become one of the major issues in landscape pattern studies. …”
Get full text

Determining the Teachers' Attitude towards "Mistake" and "Making Mistakes" in the Learning Process and Improving the Culture facing it (case study: elementary school students) by Mazhar Babaee, Hedyeh Azagh

“…The research tool was a semi-structured interview conducted by the researcher and the data format was audio. …”
Get full text

Dropout and completion in iCBT for university students: Insights from a thematic analysis by Jurrijn A. Koelen, Lisa de Koning, Matilda K. Nottage, Anke M. Klein, Claudia M. van der Heijde, Peter Vonk, Reinout W. Wiers

“…Data were analyzed using Braun and Clarke's (2012) thematic analysis. …”
Get full text

Bridging the gap: a cross-sectional study on biomedical waste management education and compliance in dental institutions of Delhi National Capital Region by Mahesh, Shakila, Hemalata, Kruthiventi, Shanta, Ramya, Vashistha, Urvi, Krishnakumar, Kavya, Arora, Samridhi, Gupta, Alpa

“…The purpose of this study was to assess BMWM knowledge, attitudes, and practices among healthcare professionals using a structured questionnaire. Data were analyzed by participants' educational levels. …”
Get full text

Caracterización agroproductiva de fincas de la provincia Mayabeque, Cuba by Luis Roberto Fundora-Sánchez, Gloria Marta Martín-Alonso, Ilén Miranda-Mora, Ramón Antonio Rivera-Espinosa, Yusimy Reyes Duque

“…The participatory action research methodology (PAR) was applied. Semi-structured interviews were used for data collection and analysis of relative frequency distribution for the studied variables was applied. …”
Get full text