A structural genomics approach to investigate Dystrophin mutations and their impact on the molecular pathways of Duchenne muscular dystrophy by Abdelbaset Mohamed Elasbali, Farah Anjum, Osama A. AlKhamees, Waleed Abu Al-Soud, Mohd Adnan, Anas Shamsi, Md. Imtaiyaz Hassan

“…BackgroundDystrophin is a key protein encoded by the DMD gene, serves as a scaffold linking the cytoskeleton to the extracellular matrix that plays a critical role in muscle contraction, relaxation, and structural integrity. Mutations, particularly single-point amino acid substitutions, can lead to dysfunctional Dystrophin, causing muscular dystrophies, with Duchenne muscular dystrophy (DMD) being the most severe form.ObjectiveThis study aimed to evaluate the effects of 184 single-point amino acid substitutions on the structure and function of Dystrophin using computational approaches.MethodsMany computational tools were used to predict the impact of amino acid substitutions on protein stability, solubility, and function. …”
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Pelvic floor structural changes during the first singleton pregnancy and the risk factors of stress urinary incontinence by Chuanqing Sun, Hongyu Yang, Keting Li, Ping He

“…Conclusions Pelvic floor structure begin to change during pregnancy, as the pregnancy advanced, the hiatal area increased gradually.…”
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The role of structural and functional parameters in designing pathology-specific tDCS protocols for primary progressive aphasia by Sagarika Bhattacharjee, P. T. Sivakumar, Ganesan Venkatasubramanian, Kenichi Oishi, Kyrana Tsapkini, S. H. Annabel Chen, Brenda Rapp, John E. Desmond, T. N. Sathyaprabha, Kaviraja Udupa, Rajan Kashyap

“…Since tDCS current distribution depends on brain structure and function, variant-specific montages are essential. …”
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Development of Deployable Reflector Antenna for the SAR-Satellite, Part 3: Environmental Test of Structural-Thermal Model by Hyun-Guk Kim, Dong-Geon Kim, Ryoon-Ho Do, Min-Ju Kwak, Kyung-Rae Koo, Youngjoon Yu

“…The sinusoidal vibration test was implemented to investigate the fundamental frequency for inplane/normal directions and evaluate the structural stability of reflector antenna. By using experimental data obtained from the thermal-balance test, the well-correlated thermal analysis model was established to execute the orbital thermal analysis. …”
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Towards Achilles Tendon Injury Prevention in Athletes with Structural MRI Biomarkers: A Machine Learning Approach by Norbert Kapinski, Karol Jaskulski, Justyna Witkowska, Adam Kozlowski, Pawel Adamczyk, Bartosz Wysoczanski, Agnieszka Zdrodowska, Adam Niemaszyk, Beata Ciszkowska-Lyson, Michal Starczewski

“…Aiming to identify relationships between the structured assessment of the Achilles tendon and its function that could support injury prevention. …”
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The Impact of Extracurricular Activities on Pre-Service Teacher Professional Development: A Structural Equation Modeling Study by Funda Uysal

“…Data from 775 pre-service teachers (71.1% female) across multiple disciplines at a Turkish university were analyzed using structural equation modeling (χ²/df = 2.855, RMSEA = 0.049, CFI = 0.93, TLI = 0.92). …”
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Correlations Between Morpho-structural Properties of the Brain and Cognitive and Motor Deficits in Individuals with Traumatic Brain Injury by Alaleh Alivar, Soha Saleh, Michael Glassen, Easter S. Suviseshamuthu, Vikram Shenoy Handiru, Didier Allexandre, Guang H. Yue

“…This study explores the relationship between neurobehavioral as well as physical function deficits and structural changes in brain white matter (WM) and gray matter (GM) in individuals with TBI by evaluating morphometric magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) data. …”
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Analysing the Functional and Structural Impact of Single Nucleotide Polymorphisms in Matrix Metalloproteinase 3 Gene: An In-silico Approach by Rejitha Ramachandran, Saritha C joseph, kc Sajeevan, Shajee S Nair

“…Aim: To identify pathogenic missense SNPs in the human MMP3 gene and analyse their effects on structure and function. Materials and Methods: This was a record-based cross-sectional study performed using data retrieved from online resources. …”
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Structural Equation Modeling and Genome-Wide Selection for Multiple Traits to Enhance Arabica Coffee Breeding Programs by Matheus Massariol Suela, Camila Ferreira Azevedo, Ana Carolina Campana Nascimento, Eveline Teixeira Caixeta Moura, Antônio Carlos Baião de Oliveira, Gota Morota, Moysés Nascimento

“…To address these challenges, we conducted a comprehensive analysis involving confirmatory factor analysis (CFA), Bayesian networks (BN), structural equation modeling (SEM), and genome-wide selection (GWS) using data from 195 arabica coffee plants. …”
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Cortical thickness and structural covariance network alterations in cerebral amyloid angiopathy: A graph theoretical analysis by Yijun Lin, Bin Gao, Yang Du, Mengyao Li, Yanfang Liu, Xingquan Zhao

“…Methods: We employed structural covariance network (SCN) analysis based on cortical thickness data from ultra-high field 7 T MRI to investigate network alterations in CAA patients. …”
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Paclobutrazol and maleic hydrazide-induced growth inhibition in warm season turfgrasses through structural and physiological differences by Muhammad Mubashir Shahzad, Gulzar Akhtar, Muhammad Asif Shehzad, Sami Ullah, Hafiz Nazar Faried, Kashif Razzaq, Fahim Nawaz, Ishtiaq A. Rajwana, Muhammad Amin, Muhammad Ahsan

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Subacromial Pain Syndrome in Breast Cancer Survivors—Are Structural Shoulder Changes Verified by Ultrasound Clinically Relevant? by Ivana Klarić-Kukuz, Jure Aljinović, Blaž Barun, Marko Roki, Benjamin Benzon, Danijela Budimir Mršić, Maja Marinović Guić, Ana Poljičanin

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Structural characterization of hydrogen bonding for antipyrine derivatives: Single-crystal X-ray diffraction and theoretical studies by N. S. Rukk, R. S. Shamsiev, D. V. Albov, S. N. Mudretsova

“…The paper is devoted to the crystal structure characterization of 5-methyl-2-phenyl4H-pyrazol-3-one (compound I) and 2-(4-chlorophenyl)-5-methyl-4H-pyrazol-3-one (compound II).Methods. …”
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Structural deformation and geochronology of the ductile shear zone along the southern margin of the Foping dome, South Qinling by YU Kecheng, SUN Shengsi, DONG Yunpeng, HUI Bo, CHENG Chao, ZHANG Bin, ZHANG Yining, LI Xinyu

“…The Yangtianba–Shimudi ductile shear zone along the dome's southern margin records information on middle–deep structural deformation during the late Triassic compressional–extensional transition, offering crucial constraints on the exhumation mechanism of the Foping dome.   …”
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Lung structural cells are altered by influenza virus leading to rapid immune protection following re-challenge by Julie C. Worrell, Kerrie E. Hargrave, George E. Finney, Chris Hansell, John Cole, Jagtar Singh Nijjar, Fraser Morton, Marieke Pingen, Tom Purnell, Kathleen Mitchelson, Euan Brennan, Clíodhna M. Daly, Jay Allan, Georgios Ilia, Vanessa Herder, Claire Kennedy Dietrich, Yoana Doncheva, Nigel B. Jamieson, Massimo Palmarini, Megan K. L. MacLeod

“…This rapid anti-viral response and increased expression of molecules required to communicate with T cells demonstrates sustained and enhanced functions following infection. These data suggest lung structural cells display characteristics of immune memory which could affect outcomes that are protective in the context of infection or pathogenic in chronic inflammatory disorders.…”
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Functional and structural characterization of the human indolethylamine N-methyltransferase through fluorometric, thermal and computational docking analyses by Matteo Ardini, Francesco Angelucci, Francesca Rea, Luca Paluzzi, Federica Gabriele, Marta Palerma, Luana Di Leandro, Rodolfo Ippoliti, Giuseppina Pitari

“…Conclusions The paper provides a foundation for thoroughly studying hINMT under consistent conditions, which is crucial for obtaining reliable kinetic data and maintaining molecular stability for future structural analysis. …”
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Structural Comparison of Raw Sodium Bicarbonate and Hydrated Lime for Dry SO₂ Removal by Robert Makomere, Lawrence Koech, Hilary Rutto, Alfayo Alugongo, Sammy Kiambi, Ngeleshi Kibambe

“…In the present investigation, sodium- and calcium-based sorbents were screened for structural and compositional variations for their subsequent application in sulphur dioxide capture. …”
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A Bidirectional Mendelian Randomization Study of Causal Relationships Between Migraine and White-Matter Structural Connectivity by Tong D, Zhang X, Xiao Z, Taothong S, Teeravarunyou P, Wu W, Wu S, Chen N, Tao S, Zhou J, Song Q, Liang F, Li Z

“…Dan Tong,1,2,* Xinyue Zhang,1,2,* Zhiyong Xiao,1,3,* Supattra Taothong,1,2 Prapawee Teeravarunyou,1,2 Wanxia Wu,1,2 Sai Wu,1,2 Nuo Chen,1,2 Siyuan Tao,1,2 Jun Zhou,1,2 Qian Song,4 Fanrong Liang,1,2 Zhengjie Li1,2,4 On behalf of International Headache Genetics Consortium (IHGC)1Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Key Laboratory of Acupuncture for Senile Disease (Chengdu University of TCM), Ministry of Education, Chengdu, Sichuan, People’s Republic of China; 3Sichuan Jinxin Xinan Women’s & Children’s Hospital (Bisheng), Chengdu, People’s Republic of China; 4National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhengjie Li, Email lzjbenjamin@163.comObjective: This study aims to investigate the potential causal relationship between migraine and white matter (WM) structural connectivity using genetic data and the Mendelian randomization (MR) analyses method.Methods: Genome-wide association study (GWAS) summary statistics for migraine (48,975 cases/540,381 controls) and 206 WM structural connectivity related imaging-derived phenotypes (IDPs) (26,333 samples) were collected. …”
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Resolving an Asteroseismic Catastrophe: Structural Diagnostics from p-mode Phase Functions off the Main Sequence by J. M. Joel Ong, Christopher J. Lindsay, Claudia Reyes, Dennis Stello, Ian W. Roxburgh

“…This expression indicates that the small separations of red giants scale primarily with their global seismic properties as $\delta {\nu }_{02}\propto {\rm{\Delta }}{\nu }^{2}/{\nu }_{{\rm{\max }}}$ , rather than being in any way sensitive to their internal structure. Departures from this asymptotic behavior, during the transition from the main-sequence to red giant regimes, have been recently reported in open-cluster Christensen–Dalsgaard (C-D) diagrams from K2 mission data. …”
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Geophysical modeling of Valle de Banderas graben and its structural relation to Bahía de Banderas, Mexico by Jorge A. Arzate, Román Álvarez, Vsevolod Yutsis, Jesús Pacheco, Héctor López-Loera

“… A gravimetric survey consisting of five lines and 483 stations, as well as a magnetotelluric (MT) survey consisting of 17 observation sites, were made in the Valle de Banderas region for the determination of the structural characteristics of the valley. Additionally, data from a previous aeromagnetic survey were analyzed to correlate them with our geophysical measurements. …”
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