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Quasi Fe MIL-53 nanozyme inducing ferroptosis and immunogenic cell death for cancer immunotherapy
Published 2025-03-01“…Quasi-metal-organic framework is a class of metal-organic framework-derived nanomaterials with a transition state from metal-organic frameworks towards metal oxide featuring porous structure and high activity. Herein an iron-based quasi-metal-organic framework nanozyme Q-MIL-53(Fe) is reported via a controlled deligandation strategy, exhibiting enhanced peroxidase-/catalase-mimic activity and glutathione depletion capacity, whose underlying mechanisms are studied via density functional theory calculations. …”
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The dual role of PGAM5 in inflammation
Published 2025-02-01“…Phosphoglycerate mutase family member 5 (PGAM5) is a novel modulator of mitochondrial homeostasis in response to mechanical stimulation. Here we review the structure and sublocalization of PGAM5, introduce its importance in programmed cell death and summarize its crucial roles in the development and progression of inflammatory diseases such as pneumonia, hepatitis, neuroinflammation and aging. …”
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Cardiac Magnetic Resonance in the Assessment of Atrial Cardiomyopathy and Pulmonary Vein Isolation Planning for Atrial Fibrillation
Published 2025-05-01“…Advanced imaging techniques, particularly cardiac magnetic resonance (CMR) imaging, have emerged as pivotal in the detailed assessment of atrial structure and function. CMR facilitates the precise measurement of left atrial volume and morphology, which are critical predictors of AF recurrence post-intervention. …”
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Conservation and valorization of Italian potato biodiversity through genotype-by-sequencing (GBS)
Published 2025-07-01“…Genetic diversity was analyzed using genotyping-by-sequencing (GBS), and comparisons were made with a global reference panel of 106 genotypes.ResultsGBS data revealed marked genetic differentiation among the Italian landraces, with three main genetic clusters showing internal structure and minimal overlap with commercial varieties. …”
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The use of deliberate practice in simulation-based surgical training for laparoscopic surgery – a systematic review
Published 2025-07-01“…Variability in DP adherence across studies influenced outcomes, with the most structured programs yielding the greatest benefits. …”
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Seasonal and Environmental Influences on the Gut Microbiota of South China Tigers (<i>Panthera tigris amoyensis</i>)
Published 2025-05-01“…Principal coordinate analysis (PCoA) based on Bray–Curtis distances revealed significant differences in the community structures of both bacterial (Adonis, R<sup>2</sup> = 0.2364, <i>p</i> = 0.001) and fungal (Adonis, R<sup>2</sup> = 0.1542, <i>p</i> = 0.001) communities across different seasons and environments. …”
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Introduction to chicken genetic resources of India: a comprehensive review
Published 2025-06-01“…Findings indicate that despite their genetic richness, several indigenous breeds face the risk of genetic dilution and population decline. To address this, structured breeding programs, in situ and ex situ conservation strategies, and genomic selection techniques must be reinforced. …”
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Making voluntary medical male circumcision services sustainable: Findings from Kenya's pilot models, baseline and year 1.
Published 2021-01-01“…Voluntary medical male circumcision is a crucial HIV prevention program for men in sub-Saharan Africa. Kenya is one of the first countries to achieve high population coverage and seek to transition the program to a more sustainable structure designed to maintain coverage while making all aspects of service provision domestically owned and implemented. …”
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Toward an enhanced policy and action framework to address energy poverty in the Iberian Peninsula: An exploratory analysis
Published 2025-05-01“…In the medium-long term, an ad hoc, easy-to-apply-to, energy efficiency subsidy program might boost the structural improvement of vulnerable households’ well-being and financial situations. …”
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Modelling POLG mutations in mice unravels a critical role of POLγΒ in regulating phenotypic severity
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High-throughput genotyping of Plasmodium vivax in the Peruvian Amazon via molecular inversion probes
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Topside Ionosphere During the Mother's Day Superstorm as Observed by Multiple LEO Spacecraft, Including SNIPE
Published 2025-07-01“…The SNIPE mission was designed to investigate micro‐scale plasma structures in Earth's ionosphere and magnetosphere. …”
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The extra-islet pancreas supports autoimmunity in human type 1 diabetes
Published 2025-04-01“…Finally, we identify lymphoid structures away from islets enriched in CD45RA+ T cells — a population also enriched in one of the inflamed islet sub-states. …”
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Quantum Vulnerability Analysis to Guide Robust Quantum Computing System Design
Published 2024-01-01“…For example, the estimated probability of success (ESP) is the state-of-the-art metric used to gauge quantum program performance. The ESP suffers poor prediction since it fails to account for the unique combination of circuit structure, quantum state, and quantum computer properties specific to each program execution. …”
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Tourism disaster management dilemmas: Insights from Mandalika, Indonesia
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The role of social-psychological factors in the adoption of push-pull technology by small-scale farmers in East Africa: Application of the theory of planned behavior
Published 2025-01-01“…Nine hundred and seventy-one (971) cereal growers comprising PPT users and non-users were interviewed in Kenya, Uganda, Tanzania, and Rwanda using a structured questionnaire. Utilizing the Partial Least Square-Structural Equation Modelling (PLS-SEM) and Artificial Neural Network (ANN), this study revealed a significant positive influence of TPB conceptual elements attitudes, subjective norms, and perceived behavioral control on farmers’ intentions to adopt or expand the land area under PPT. …”
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