A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…., Walnut Creek, CA, USA; 12Private Practice, San Francisco, CA, USACorrespondence: Jon E Block, Private Practice, 2210 Jackson Street, Ste. 401, San Francisco, CA, 94115, USA, Tel +1 415-775-7947, Email jb@drjonblock.comBackground: There is renewed interest in the intervertebral disc as a target for treatments aimed at ameliorating lumbar discogenic pain by restoring and preserving the natural structure and function of this component of the vertebral motion segment.Methods: Using a modified Delphi methodology involving a panel of 11 experts, we developed a simple, understandable clinical algorithm to serve as a foundation for objective decision making regarding the diagnosis and treatment of lumbar discogenic pain throughout the entire continuum of care. …”
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Particularities in differential diagnostics of epileptogenic brain malformations on the low-field MRI-device by V. S. Khalilov, A. A. Kholin, B. R. Bakaeva, M. Yu. Bobylova, Kh. Sh. Gazdieva

“…In 24 patients were revealed structural brain changes that have neuroradiological signs of brain malformations. …”
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A compound heterozygous mutation in ZP1 and two novel heterozygous cis mutations in ZP3 causes infertility in women presenting with empty follicle syndrome by Xiaoxiao Wang, Yingxue Liu, Guanghui Yuan, Jingjie Yang, Xiaowen Liu, Shuyuan Chen, Huaiqian Dou, Panpan Lu, Linfang Han, Duan Li, Cuifang Hao

“…Computer simulation of protein structure was used to assess the pathogenicity of the variants on the proteins. …”
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Laminar organization of the anterior olfactory nucleus—the interplay between neurogenesis timing and neuroblast migration by Eduardo Martin-Lopez, Eduardo Martin-Lopez, Bowen Brennan, Bowen Brennan, Marion Lefèvre, Marion Lefèvre, Natalie J. Spence, Natalie J. Spence, Kimberly Han, Kimberly Han, Charles A. Greer, Charles A. Greer, Charles A. Greer

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Metabolomic liquid biopsy dynamics predict early-stage HCC and actionable candidates of human hepatocarcinogenesis by Kornelius Schulze, Tim Daniel Rose, Lorenz Adlung, Manuela Peschka, Francesca Pagani, Joao Gorgulho, Thorben W. Fründt, Ismail Labgaa, Philipp K. Haber, Carolin Zimpel, Darko Castven, Arndt Weinmann, Teresa Garzia-Lezana, Moritz Waldmann, Thomas Renné, Hannah Voß, Manuela Moritz, Dorian Orlikowski, Hartmut Schlüter, Jan Baumbach, Myron Schwartz, Ansgar W. Lohse, Samuel Huber, Bruno Sangro, Rocio I.R. Macias, Laura Izquierdo-Sanchez, Jesus M. Banales, Henning Wege, Jens U. Marquardt, Augusto Villanueva, Josch Konstantin Pauling, Johann von Felden

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Mannich Base Derived from Lawsone Inhibits PKM2 and Induces Neoplastic Cell Death by Lucas Rubini-Dias, Tácio V. A. Fernandes, Michele P. de Souza, Déborah Hottz, Afonso T. Arruda, Amanda de A. Borges, Gabriel Ouverney, Fernando de C. da Silva, Luana da S. M. Forezi, Gabriel Limaverde-Sousa, Bruno K. Robbs

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Sm2O3-induced superconductivity enhancements in bulk Y-123 ceramics synthesized via a novel modified thermal decomposition method by Ryad Alhadei Mohamed Arebat, Mohd Mustafa Awang Kechik, Yap Siew Hong, Chen Soo Kien, Lim Kean Pah, Hussien Baqiah, Fatma Barood, Syahrul Humaidi, Hoo Keong Peh, Abdul Halim Shaari, Muhammad Kashfi Shabdin, Muralidhar Miryala

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Thymic characteristics in patients with autoimmune diseases: a multicentre radiological observational studyResearch in context by Haoxiao Chang, Junqiang Yan, Anxin Wang, Ningning Wang, Peng Liu, Yemin Shi, Xin Zhao, Jinqiao Zhu, Yuan Cai, Xue Xia, Yunyi Hao, Shiyi Yin, Jing Wang, Xinli Wang, Lina Sun, Jia Ma, Xiaoyu Huang, Haonan Guan, De-Cai Tian, Kaibin Shi, Ganqin Du, Wenhao Huang, Guoyan Qi, Hao Li, Yongjun Wang, Fu-Dong Shi, Zhang Zhang, Wei-Na Jin

“…A semi-automatic algorithm was developed and employed for the analysis of thymic radiological characteristics, encompassing structural features and density. Thymic fatty replacement was evaluated using a four-point visual scoring scale (0–3). …”
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Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context by Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu

“…We estimated familial aggregation/coaggregation using generalised estimating equations, heritability and genetic correlations using structural equation modelling. We also analysed ∼30,000 genotyped MDD cases from the UK Biobank and a Swedish cohort to explore which polygenic risk score (PRS) may predispose individuals to psychotic MDD. …”
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Assessment of microvascular flow in human atherosclerotic carotid plaques using ultrasound localization microscopyResearch in context by Henri Leroy, Louise Z. Wang, Anatole Jimenez, Nassim Mohamedi, Clément Papadacci, Pierre Julia, Salma El Batti, Jean-Marc Alsac, Jonas Sitruk, Armelle Arnoux, Patrick Bruneval, Emmanuel Messas, Tristan Mirault, Guillaume Goudot, Mathieu Pernot

“…ULM was performed by localising and tracking individual MB centres to reconstruct the neovessels structure with a resolution of around 60 μm. Plaques were manually segmented on the images to quantify the number of neovessels and various haemodynamic metrics inside the plaques. …”
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Evaluation and Comparison of Resource sustainability of Two Forest Reserves in Hamadan Province by Mohsen Akbari, Alireza Ildoromi, Farhad Ghasemi Aghbash, Iman Pajohan

“…Biodiversity, with the lowest score in both reserves including legal measures and organizational structure, economic and social functions, forest production functions, forest resources, conservation functions with the lowest score have the greatest impact on the instability of two forest reserves respectively. …”
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改性秸秆灰负载Pt催化甘油氧化性能研究Glycerol oxidation catalyzed by modified straw ash supported Pt by 王聪莹1， 于静2， 崔佳欣1 WANG Congying1，YU Jing2，CUI Jiaxin1

“…In order to achieve high value utilization of biomass, Pt-based catalysts of Pt/ash-b, Pt/ash-a, Pt/ash-ba and Pt/ash-CeO2 were prepared by pre-treating straw ash using alkali modification, acid modification, combined acid and alkali modification, and introduction of CeO2, respectively. The composition, structure, loading amount of Pt, size of Pt particle, surface acidity and alkalinity, and Pt reduction activity of the catalysts were determined by X-ray fluorescence spectroscopy (XRF), X-ray diffraction (XRD), inductively coupled plasma-atomic emission spectroscopy (ICP-OES), transmission electron microscopy (TEM), CO2 programmed temperature-raising desorption (CO2-TPD) and NH3 programmed temperature-raising desorption (NH3-TPD), and hydrogen-programmed temperature-raising reduction (H2-TPR), respectively. …”
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Transfer learning‑based attenuation correction in 99mTc-TRODAT-1 SPECT for Parkinson’s disease using realistic simulation and clinical data by Wenbo Huang, Han Jiang, Yu Du, Haiyan Wang, Hao Sun, Guang-Uei Hung, Greta S. P. Mok

“…Results With 8 available clinical datasets, TLAC-MC achieved the best result in Normalized Mean Squared Error (NMSE) and Structural Similarity Index Measure (SSIM) (TLAC-MC; NMSE = 0.0143 ± 0.0082/SSIM = 0.9355 ± 0.0203), followed by DLAC-AUG, DLAC-MIX, TLAC-ANA, DLAC-CLI, DLAC-MC, ChangAC and NAC. …”
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Sintesis Katalis Fe/SOD Berbasis Lempung Alam Maredan Untuk Mendegradasi Zat Warna Metilen Biru by Elis Damayanti, Amir Awaluddin, Muhdarina Muhdarina

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Nanoscale Organic Contaminant Detection at the Surface Using Nonlinear Bond Model by Hendradi Hardhienata, Muhammad Ahyad, Fasya Nabilah, Husin Alatas, Faridah Handayasari, Agus Kartono, Tony Sumaryada, Muhammad D. Birowosuto

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Paradigms of the agricultural system in times of COVID-19 by Luis Edgar Blanco-Capia

“…It is time to reflect, change the model and paradigm1, planning structural policies in the food industry that allow the implementation of digital solutions, with the aim of promoting productive development10. …”
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Desarrollo y validación de una prueba escrita objetiva de elección múltiple para evaluar el conocimiento del entorno para el acondicionamiento físico (CENAFI) en escolares (Develo... by Santiago Guijarro-Romero, Daniel Mayorga-Vega, Carolina Casado-Robles, Jesús Viciana

“…The phases of the test validation were: (1) Construction and definition of the structure and purpose of the test; (2) content validation by experts; (3) piloting; (4) depuration and application of the definitive instrument; (5) test-retest reliability assessment; and (6) discriminant validity assessment. …”
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Possibilities and reserves of using electronic medical records data in health information systems on the example of assessing the causes of visits to outpatient clinics and death i... by I. V. Samorodskaya, R. N. Shepel, I. V. Klyuchnikov, M. M. Lukyanov, S. Yu. Martsevich, E. P. Kakorina, O. M. Drapkina

“…The data obtained confirm the need to develop measures aimed at standardization, structuring and a single regulatory system for entering data on the reasons for patient visits to outpatient clinics and the causes of their death in HIS. …”
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POTENSI PEMBENTUKAN LAPISAN SUPER DAN ULTRA KERAS SENYAWA KOMPOSIT NITRIDA MENGGUNAKAN KAIDAH ELEKTRODEPOSISI by Esmar Budi

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Measuring Faculty Excellence: Introducing a Model by Anoush Dehnadi Moghadam

“…There are various criteria for this evaluation, which generally focus more on research performance, while the main objective of hiring faculty members has been the development of education. The common structure of academic scoring,  rewarding  research  More than teaching (4). …”
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