A review of circular RNAs in colorectal cancer: insights into biomarker discovery and therapeutic targeting by Sibin Nambidi, Karunakaran Bhuvaneswari Shruthi, Sujatha Padmanaban Kanimozhe, Antara Banerjee, Suresh Babu Kondaveeti, Asim K. Duttaroy, Surajit Pathak

“…Circular RNAs (circRNAs), a subclass of endogenous ncRNAs characterized by their covalently enclosed loop structure, demonstrate greater stability than linear RNAs, making them potential candidates for clinical applications. …”
Get full text

Youth Obesity: Sport as a Solution Strategy by Krzysztof Pietrzak, Małgorzata Wasilewska, Sebastian Polok, Karol Demel

“… Purpose: This study examines organized sports as a multisectoral intervention against youth obesity, emphasizing physiological, psychosocial, and structural motivations. Materials and Research Methods: Long term cohort analyses (e.g., Finland’s 21-year tracking [7]), randomized trials, and regional case studies (Poland’s rural-urban disparities [10], Italy’s post-pandemic park programs [15]) were included. …”
Get full text

Characterization and Expression Analysis of PUB Gene Family Involved in Drought Stress Response in Trifoliate Orange (<i>Poncirus trifoliata</i>) by Bobo Song, Sanpeng Jin, Xuchen Gong, Yong Liu, Dechun Liu, Li Yang, Wei Hu, Liuqing Kuang, Jie Song

“…Phylogenetic tree analysis indicated that 170 PUB proteins from trifoliate orange, <i>Arabidopsis thaliana</i>, and tomato were clustered into five subfamilies. Gene structure, conserved domain, and motif analyses revealed diverse exon–intron and motif organizations of <i>PtrPUB</i> genes, suggesting potential functional differentiation among <i>PtrPUBs</i>. …”
Get full text

The role of influencer content value and credibility in purchase intention by Ahmad Shaheen, Abdullah Khataan, Abdelrehim Awad, Anwar Yahia Shams Eldin, Awadia Elnour

“…Employing a descriptive-explanatory design, survey data were collected from 633 social media users. Analysis via Structural Equation Modeling (SEM) revealed that all examined dimensions of influencer content value significantly and positively influence purchase intention, with entertainment value (r = 0.878 in correlation analysis, SEM estimate = 0.150) and functional value (r = 0.819 in correlation, SEM estimate = 0.118) demonstrating particularly strong contributions. …”
Get full text

Can China’s national fitness policy contribute to achieving universal health? Analysis based on the three-dimensional framework by Defeng Dong, Bing He, Jianda Kong, Aitong Zhou, Mei Lv, Dianbo Zhang, Chen Dong

“…In terms of policy tools, there is an overall structural imbalance and internal disarray, with environmental policy tools dominating, supplemented by supply-side policies, while demand-side policies are insufficient. …”
Get full text

Evaluation Method of Pyroclastic Rock Reservoir Based on Gravel Parent Rock Composition by DONG Lei, LI Wentao, DING Yonghao, ZHANG Zhiguo, XIA Xue, PANG Jiarui, GAO Feng

“…As a result, the calculation accuracy of reservoir porosity parameters is low, the pore structure is complex, and fluid identification is difficult. …”
Get full text

Psychometric validation of type 2 Diabetes Distress Assessment System in an Indian type 2 diabetes population by Baby Sharma, Pramod Tripathi, Nidhi Kadam, Diptika Tiwari, Anagha Vyawahare, Thejas Kathrikolly, Malhar Ganla

“…Statistical analyses included descriptive statistics, Principal Component Analysis (PCA), Exploratory Factor Analysis (EFA), Confirmatory Factor Analysis (CFA), and Structural Equation Modeling (SEM), using IBM SPSS, R, and AMOS software. …”
Get full text

Enhancing self-care management among women with type 2 diabetes mellitus by Na’eemah Zaini, Idayu Badilla Idris, Norfazilah Ahmad, Syahnaz Mohd Hashim, Nik Nairan Abdullah, Nadia Aqilla Shamsusah

“…A cross-sectional study was conducted among 330 female patients recruited through multistage sampling from nine health clinics in Malaysia. Structural equation modeling (SEM) was used to analyze the relationships between these factors. …”
Get full text

The Role of Immersive Virtual Realities: Enhancing Science Learning in Higher Education by Talia Tene, Marco Guevara, Gabriel Moreano, John Vera, Cristian Vacacela Gomez

“…These articles were further analyzed to identify distinct structural elements regarding VR and AR interventions and their effects on educational outcomes. …”
Get full text

Genomic characterization and insights into the belted coat pattern of a local, reconstituted pig population by Samira Giovannini, Maria Giuseppina Strillacci, Raffaella Milanesi, Caterina Altissimi, Massimo Biagetti, Francesca Maria Sarti

“…Genetic analyses were conducted to assess population structure and diversity, with comparisons made to other Italian pig breeds and wild boars. …”
Get full text

ATF7IP inhibits Sorafenib-induced ferroptosis in hepatocellular carcinoma cells by inhibiting CYB5R2 transcription and stabilizing PARK7 protein by Yijie Su, Sirui Huang, Yang Duan, Liang Zhang, Shengyun Feng, Yingge Lv, Bei Lan, Chenghao Xuan

“…Ferroptosis, an iron-dependent form of programmed cell death, arises from the accumulation of lipid peroxides at toxic levels. …”
Get full text

Efficacy of Recombinant Genetic Diagnostic Tools for Foot-and-Mouth Disease Virus (FMDV) by Mai M. Abd El-Rahman, Rokaya H. Shalaby, Alaa A. E .El-Kholy, Noura R. Mohamed, Shereen H. B. Elwakeel

“…The virus's seven serotypes and numerous genetic subtypes complicate its diagnosis in both at-risk and endemic areas, facing any control programs. The non-structural polypeptide (NSP) 3ABC of FMDV is the most reliable for serotype-independent antibody detection, and an enzyme-linked immunosorbent assay (ELISA) based on this has proven reliable. …”
Get full text

Navigating relationships and tensions: how professionals who treat substance use disorders view their role in preventing child abuse and neglect by Paulo Padilla-Petry, Nuria Fuentes-Peláez, Anna Fantova-Romero

“…They discussed the importance and fragility of the therapeutic bond, structural deficiencies in their services, and the challenges of working with CWS. …”
Get full text

Knowledge, attitudes, and practices of pregnant and postpartum women regarding stress urinary incontinence by Qin Dong, Shenxian Wan, Ruihua Wang, Sanshan Guo, Hong Shen, Ningjuan Wang, Wenting Cai, Luxi Cai, Wei Zhao

“…Findings revealed median scores: knowledge 20.00 [12.00, 28.00] (range: 0–44), attitudes 21.00 [19.75, 24.00] (range: 8–40), and practices 26.00 [22.00, 31.00] (range: 8–40). Structural equation modeling (SEM) showed knowledge directly influenced attitudes (β = -0.153, p < 0.001), while both knowledge (β = 0.522, p < 0.001) and attitudes (β = -0.128, p = 0.004) significantly impacted practices. …”
Get full text

Electrical Characteristics of Mesh-Type Floating Gate Transistors for High-Performance Synaptic Device Applications by Soyeon Jeong, Jaemin Kim, Hyeongjin Chae, Taehwan Koo, Juyeong Chae, Moongyu Jang

“…Individual floating gates with dimensions of 3 µm × 3 µm are arranged in an array configuration to form the floating gate structure. The Mesh-FGT is composed of an Al/Pt/Cr/HfO₂/Pt/Cr/HfO₂/SiO₂/SOI (silicon-on-insulator) stack. …”
Get full text

Design and evaluation of a multi-epitope DNA vaccine against HPV16 by Lanfang Zhu, Xiangjie Cui, Zhiling Yan, Yufen Tao, Lei Shi, Xinwen Zhang, Yufeng Yao, Li Shi

“…Subsequently, through meticulous selection of T-cell epitopes and other necessary elements, a multi-epitope vaccine was constructed, exhibiting good immunogenic, physicochemical, and structural characteristics. Furthermore, in silico simulations showed that the vaccine not only interacted well with toll-like receptors (TLR2/TLR3/TLR4), but also induced a strong innate and adaptive immune response characterized by elevated Th1-type cytokines, such as interferon-gamma (IFN-γ) and interleukin-2 (IL2). …”
Get full text

A roadmap for personalized medicine: the findings of the IC2PerMed project by Flavia Beccia, Francesco Andrea Causio, Marzia Di Marcantonio, Ilda Hoxhaj, Chiara Cadeddu, Melissa Campagno, Lena Schleicher, Carmen Fotino, Maike Tauchert, Marta Lomazzi, Lili Wang, Wenya Wang, Huiyao Huang, Walter Ricciardi, Stefania Boccia, Stefania Boccia

“…The roadmap promotes best practice exchange and addresses potential barriers to PM adoption. It outlines structural actions including enhancing health literacy, fostering intersectoral and international collaboration, ongoing review of emerging technologies, and facilitating innovation market entry through needs assessment and Health Technology Assessment. …”
Get full text

Accessing a New Population of Supermassive Black Holes with Extensions to the Event Horizon Telescope by Xinyue Alice Zhang, Angelo Ricarte, Dominic W. Pesce, Michael D. Johnson, Neil Nagar, Ramesh Narayan, Venkatessh Ramakrishnan, Sheperd Doeleman, Daniel C. M. Palumbo

“…We find that the linearly polarized structure evolves substantially with the Eddington ratio, with greater evolution at larger inclinations, complicating potential spin inferences for inclined sources. …”
Get full text

Intrincada construcción de identidad profesional y relaciones de poder: percepciones en docentes universitarios de Educación Física (Intricate construction of professional identity... by Yanet Amanda Maquera-Maquera, Saúl Bermejo-Paredes, Erika Olivera Condori, Rogelio Domingo Cahuana Tapia, Yony Martín Pino Vanegas, Efrain Humberto Yupanqui Pino, Silo Nahun Chuquicallata Paricahua, Henry Mark Vilca Apaza

“…Institutional programs are needed to build university identity processes. …”
Get full text

exoALMA. XVI. Predicting Signatures of Large-scale Turbulence in Protoplanetary Disks by Marcelo Barraza-Alfaro, Mario Flock, William Béthune, Richard Teague, Jaehan Bae, Myriam Benisty, Gianni Cataldi, Pietro Curone, Ian Czekala, Stefano Facchini, Daniele Fasano, Misato Fukagawa, Maria Galloway-Sprietsma, Himanshi Garg, Cassandra Hall, Jane Huang, John D. Ilee, Andrés F. Izquierdo, Kazuhiro Kanagawa, Eric W. Koch, Geoffroy Lesur, Cristiano Longarini, Ryan A. Loomis, Ryuta Orihara, Christophe Pinte, Daniel J. Price, Giovanni Rosotti, Jochen Stadler, Gaylor Wafflard-Fernandez, Andrew J. Winter, Lisa Wölfer, Hsi-Wei Yen, Tomohiro C. Yoshida, Brianna Zawadzki

“…Supporting these scenarios requires further methodically comparing the predicted perturbations and the observed disks’ complex dynamic structure.…”
Get full text