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9642
Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma
Published 2025-07-01“…Abstract Background We developed an integrated multi-omics analysis in metastatic melanoma (MM) cohorts to associate DNA methylation profiles with tumor progression, survival, response to adjuvant immunotherapy, structure of the tumor immune microenvironment and transcriptional programs of immunity and melanoma differentiation. …”
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The application of blockchain with a comparative approach and its impact on risk, flexibility and internal control evaluation
Published 2024-09-01“…Blockchain is essentially a public ledger, where groups of transactions or events are recorded and stored in a chain-like data structure; this approach creates a fast yet secure way to transfer funds. …”
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Knowledge management in higher education: a meta-synthesis of success factors, challenges, and implementation strategies
Published 2024-12-01“…Implement mentoring programs for tacit knowledge transfer10. Regular assessment of knowledge management effectivenessThe findings emphasize the need for a holistic approach that addresses cultural, structural, and technological dimensions simultaneously. …”
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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity
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Mannich Base Derived from Lawsone Inhibits PKM2 and Induces Neoplastic Cell Death
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Dynamics of turnover of sugar-lowering drugs in the retail segment of the pharmaceutical market from 2020 to 2024
Published 2025-07-01“…Despite maintaining the leading position of metformin, the consumption structure is shifting towards more expensive schemes. …”
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Propuesta metodológica para la enseñanza de la biomedicina orientada a las herramientas de detección y diagnóstico molecular para estudiantes de Medicina
Published 2025-03-01“…Methods: The proposed structure is based on the requirements of basic science subjects that students must complete to understand molecular diagnostics. …”
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Relationship between prenatal anxiety, depression, pregnancy stress and their social determinants
Published 2025-08-01“…Given that psychological problems during pregnancy may lead to short-term and long-term adverse outcomes for both mothers and infants, clarifying their network structure and core social determinants holds important public health significance for formulating regional intervention strategies. …”
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Evaluating snow depth retrievals from Sentinel-1 volume scattering over NASA SnowEx sites
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MSA-3D: Dissecting Galaxies at z ∼ 1 with High Spatial and Spectral Resolution
Published 2025-01-01“…Here we describe the multiplexed slit-stepping method, which is >15 times more efficient than the NIRSpec IFS mode for our program. As an example of the data quality, we present a case study of an individual galaxy at z = 1.104 (stellar mass M _* = 10 ^10.3 M _⊙ , star formation rate, SFR = 3 M _⊙ yr ^−1 ) with prominent face-on spiral structure. …”
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SCREEN ATTRACTIONS: BETWEEN VISUAL AND NARRATIVE / АТТРАКЦИОНЫ ЭКРАНА: МЕЖДУ ВИЗУАЛЬНЫМ И НАРРАТИВНЫМ
Published 2021-03-01“…Based on a number of provisions of aesthetics and film semiotics, the article interprets the structural features of the attractions of screen civilization and analyzes their varieties in the context of serial art products that reveal their structural and receptive specifics. …”
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The Characteristic of Measles Epidemic Process in Kyrgyz Republic
Published 2021-09-01“…The data obtained statistically processed using the Excel program. The critical level of significance is p = 0.05. …”
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A DISCUSSÃO DAS RELAÇÕES ÉTNICO-RACIAIS NOS PROGRAMAS DE PÓS-GRADUAÇÃO EM EDUCAÇÃO DA REGIÃO NORDESTE(2009-2016)
Published 2020-12-01“…THE DISCUSSION OF ETHNIC RACIAL RELATIONS IN POSTGRADCATE PROGRAMS IN EDUCATION OF NORTHEAST REGION (2009-2016) Abstract This aticle aimstoknow thw discussion of the ethnic racial relations in postgraduate programs in education of northeast region (2009-2016) by means of the survey of techer intelectual production, structure analysis and organicity of the modus operandi oh the programs against the requirements of legal frameworks related to diversity and specifically, the ethnic-racial relations. …”
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Comparative transcriptome analysis reveals molecular mechanisms of resistance in Chinese cabbage to Plasmodiophora brassicae pathotype 11
Published 2025-01-01“…Microscopic analysis at 21 dai revealed that the resistant cultivar (JP) root structure remained largely unaffected, while the roots of the susceptible cultivar (83-1) exhibited significant tissue distortion and gall formation, underscoring the effectiveness of the resistance mechanisms. …”
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ZNFX1 suppresses apoptosis-associated mRNA stability in cardiomyocyte to protect against myocardial infarction
Published 2025-09-01“…Here, we report that ZNFX1 plays a protective role in MI by degrading mRNA of apoptosis-related genes, which possess highly structured 3′UTRs. Collectively, this study provides a novel insight into the regulatory mechanisms of programmed cell death, potentially uncovering new targets for therapeutic intervention in diseases where apoptosis is a critical factor.…”
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Psychometric evaluation of EQ-5D-5L in OHCA survivors from the TTM2 trial: a post hoc analysis
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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency
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