Synthesis, physical-chemical and biological properties of 1,8-disubstituted compounds of theobromine. III. 8-Amino-p-chlorobenzyltheobromines by D. G. Ivanchenko, M. I. Romanenko, A. M. Kamyshny, N. M. Polishchuk

“…There have been developed available laboratory-based methods for the synthesis of 8-aminosubstituted 1-p-chlorobenzyltheobromine, the structure of which has been proved by data obtained from elemental analysis and NMR- spectroscopy. …”
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Efektivitas Kombinasi Kitosan dan Ampas Teh Sebagai Adsorben Alami dalam Menurunkan Konsentrasi Timbal Pada Limbah Cair PT PXI by Dhonny Suwazan, Nisa Nurhidayanti

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Adherence to Medical Treatment in Elderly Patients with Coronary Artery Disease in the Settings of Primary Outpatient Care by S. K. Zyryanov, S. B. Fitilev, A. V. Vozzhaev, I. I. Shkrebneva, N. N. Shindryaeva, D. A. Klyuev, L. N. Stepanyan, A. M. Lutsenko, A. T. Tsai, A. A. Danilova

“…Medical history and structure of pharmacotherapy do not influence level of adherence in this population. …”
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The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways by Chao-Yu Hsu, Jyun-Yi Li, Jyun-Yi Li, Wei-Ru Huang, Wei-Ru Huang, Tsai-Ling Liao, Tsai-Ling Liao, Hsiao-Wei Wen, Chi-Young Wang, Chi-Young Wang, Lon-Fye Lye, Brent L. Nielsen, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu

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Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects by Jeongah Oh, Sneha Muralidharan, Qing Zhao, Johannes Scholz, Iris D. Zelnik, Shani Blumenreich, Tammar Joseph, Tamir Dingjan, Pradeep Narayanaswamy, Hyungwon Choi, Heiko Hayen, Federico Torta, Anthony H. Futerman

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Integrating multi-omics with neuroimaging and behavior: A preliminary model of dysfunction in football athletes by Sumra Bari, Nicole L. Vike, Khrystyna Stetsiv, Alexa Walter, Sharlene Newman, Keisuke Kawata, Jeffrey J. Bazarian, Linda Papa, Eric A. Nauman, Thomas M. Talavage, Semyon Slobounov, Hans C. Breiter

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Sources of dissolved organic matter in initial rainwater and its photochemical activity by Yanting Xi, Sihan Fan, Yixin Liu, Danni Cui, Zhicheng Liao, Ziwei Guo, Chaochao Lai, Haodong Zhang, Zhe Zhang, Fengxia Han, Huan He, Bin Huang, Xuejun Pan

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SELECTION CRITERIA OF COMPOUNDS FOR DEVELOPMENT OF HIGH-POTENT ANALGESICS AND OTHER CNS DRUGS by A. V. Sosnov, F. M. Semchenko, V. N. Tohmahchi, A. A. Sosnova, M. I. Vlasov, A. S. Radilov, D. V. Krivorotov

“…In order to analyze best practices, develop a strategy for highly effective controlled medicinal and veterinary drugs (analgesics, anesthetics, antidotes and other vital therapies) and coordinate theirdevelopment and production it is necessary to create competent management structure combining the tasks of provision of civilian population and personnel of national defense agencies of effective and safe drugs.…”
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Design and beam dynamics studies of low energy beam transport for MEHIPA by Pallavi Priyadarshini, Jose V Mathew, Rajni Pande, SVLS Rao, Rajesh Kumar

“…Low Energy High Intensity Proton Accelerator (LEHIPA), the initial stage of India’s Accelerator Driven Subcritical System (ADSS) program has been commissioned to the design energy of 20 MeV at BARC, Mumbai. …”
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In silico and in vivo Study of the Anti-Inflammatory Activity of Azomethine Derivatives of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 2-substituted 5,6,7,8-tetra... by Chiriapkin, A.S., Kodonidi, I.P., Abisalova, I.L., Diakova, I.N.

“…In silico prediction of anti-inflammatory activity was performed using the AutoDock 4.0 program. The virtual structures of the test compounds were constructed in HyperChem 8.0.4. …”
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Efficacy of neoadjuvant chemotherapy with docetaxel and cisplatin in patients with squamous cell carcinoma of the oral cavity at high risk of progression by S. I. Kutukova, Yu. V. Ivaskova, N. P. Beliak, G. A. Raskin, A. A. Varankina, A. I. Yaremenko, A. Ya. Razumova, A. O. Cheremnykh, M. F. Manna, R. V. Orlova

“…At the 1st stage of our study, we retrospectively analyzed the data of 98 patients and determine that the NACT for patients with oral cavity squamous cell carcinoma, with 3 or more factors of an unfavorable prognosis (peripheral blood parameters indicating the presence of systemic inflammation, reduced level of infiltration of tumor structures by CD8‑tumor infiltrating lymphocytes and low expression of programmed death-ligand 1 (PD-L1) on tumor and immune cells) significantly reduces the risk of death and disease progression: hazard ratio 0.33; 95 % confidence interval 0.13–0.86; p = 0.0231. …”
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Obstacles to effective communication between physical/occupational therapists and patients in the Saudi Arabian context: a cross-sectional study by Turki Aljuhani, Abrar M. Al-Mutairi, Abdullah Alfraih, Mohammed Alharbi, Turki AlAmri, Ali Alahmari, Abdulaziz Alotaibi, Mohammed Senitan

“…Future research should focus on longitudinal studies and specific communication training programs.…”
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POSSIBILITIES OF DIAGNOSIS OF RADIATION INJURIES AND REHABILITATION OF PATIENTS AFTER COMBINED TREATMENT OF MALIGNANT TUMORS OF THE BREAST by A. V. Kondakov, M. E. Borodina, O. V. Andrianov, N. I. Rozhkova

“…To develop and introduce into practice health facility individual programs of rehabilitation treatment and rehabilitation after combined treatment of breast cancer with the use of thermal imaging diagnostic method.Materials and methods. …”
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Construction of a comprehensive library of repeated sequences for the annotation of Citrus genomes by Delphine Giraud, Nathalie Choisne, Marilyne Summo, Stéphanie Sidibe-Bocs, Héléna Vassilieff, Gilles Costantino, Gaetan Droc, Pierre-Yves Teycheney, Florian Maumus, Patrick Ollitrault, François Luro

“…The exploration of repeat position insertions along chromosomes using the developed web interface, RepeatLoc Citrus, will also make it possible to further investigate the role of transposable elements and endogenous caulimovirids in genome structure and gene regulation in Citrus species.…”
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Biological protection of plants in agricultular landscape—state of the art, problems and ways of their decision by Sokolov M S, Kolombet L V

“…In polyconsorcial agroecosystems, the following major ecological functions are permanently realized:<list list-type="simple"> <list-item> · Self-management of the structure (and number dynamics) of bioresources; </list-item> <list-item> · Plastic self-restoration of their structure (broken by abiotic stress agents); </list-item> <list-item> · Self-maintenance of positive balance of biofilic elements and moisture in soil substrates; </list-item> <list-item> · Effective autopurification of soils from polluting substances. …”
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Balancing ethics and conservation: Assessing short‐term behavioral impacts of biopsy sampling in a recovering whale population by Leena Riekkola, Simon Childerhouse, Rochelle Constantine, Ros Cole, Robert Harcourt, Dorothea Heimeier, Dave Lundquist, Catherine Meyer, Mike Ogle, Debbie Steel, Esther Stuck, Aimee van derReis, Emma L. Carroll

“…Abstract Long‐term monitoring programs based on individual identification have provided a sound basis for monitoring the status of endangered and recovering species. …”
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Phylogenomic analysis of bromodomain genes in cotton (Gossypium spp.) and their potential roles in abiotic stress tolerance by Muhammad Tayyab, Muhammad Hassan Taj, Ali Ijaz Ahmad, Faiza Rehman Rana, Muhammad Shahzaib, Rana Muhammad Atif, Muhammad Tehseen Azhar, Sultan Habibullah Khan, Ishaq Ahmad Mian Kakakhel, Shoupu He, Iqrar Ahmad Rana

“…Gene duplication analysis revealed 78.85% of duplications were segmental and 21.15% were tandem among 104 in-paralogous gene pairs, contributing to BRD gene expansion. Gene structure, motif, and domain analyses demonstrated that most genes were intron-less and conserved throughout evolution. …”
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Bis(7)-harmine derivatives as potential multi-target anti-Alzheimer agents by Hongtao Du, Hongtao Du, Hongtao Du, Fang Ma, Fang Ma, Yuanyuan Cao, Miaoyan Bai, Xinyi Gao, Ziyi Yang, Yang Xu, Yan Yan, Yan Yan

“…In this study, a series of bis(7)-harmine derivatives were designed and synthesized as multifunctional drugs for the treatment of AD.MethodsThe derivatives were synthesized by chemical methods and their structure was confirmed by nuclear magnetic resonance (NMR). …”
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Seasonal and Environmental Influences on the Gut Microbiota of South China Tigers (<i>Panthera tigris amoyensis</i>) by Li Zhou, Xiyao Xu, Zhirong Zhang, Xu Zhang, Kaixiong Lin, Hongxing Luo, Cheng Huang, Xipan Lin, Chunli Zhang, Yan Qing, Liwei Teng, Zhensheng Liu

“…Principal coordinate analysis (PCoA) based on Bray–Curtis distances revealed significant differences in the community structures of both bacterial (Adonis, R² = 0.2364, <i>p</i> = 0.001) and fungal (Adonis, R² = 0.1542, <i>p</i> = 0.001) communities across different seasons and environments. …”
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Hierarchizing multi-scale environmental effects on agricultural pest population dynamics: a case study on the annual onset of Bactrocera dorsalis population growth in Senegalese or... by Caumette, Cécile, Diatta, Paterne, Piry, Sylvain, Chapuis, Marie-Pierre, Faye, Emile, Sigrist, Fabio, Martin, Olivier, Papaïx, Julien, Brévault, Thierry, Berthier, Karine

“…Implementing integrated pest management programs to limit agricultural pest damage requires an understanding of the interactions between the environmental variability and population demographic processes. …”
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