Novel Thiazole-Fused [4,5-<i>g</i>] or [5,4-<i>g</i>]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation by Nathan Broudic, Alexandra Pacheco-Benichou, Cécile Corbière, Blandine Baratte, Thomas Robert, Stéphane Bach, Hélène Solhi, Rémy Le Guével, Corinne Fruit, Thierry Besson

“…<b>Methods:</b> An innovative protocol allowed to obtain the target structures. The synthesis of inverted thiazolo[4,5-<i>h</i>] and [5,4-<i>h</i>]quinazolin-8-one derivatives was also explored with the aim of comparing biological results. …”
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A systematic review of microsimulation models for skin cancer by Caroline G. Watts, Kirstie G. McLoughlin, Stephen Wade, Amelia K. Smit, H. Peter Soyer, Pablo Fernandez-Peñas, David C. Whiteman, Pascale Guitera, Gillian Reyes-Marcelino, Karen Canfell, Anne E. Cust, Michael Caruana

“…To inform the development and improvement of skin cancer focussed microsimulation models, we conducted a systematic review and narrative synthesis of published skin cancer models to assess the structure, parameterisation, and assumptions. Methods The electronic databases OVIDMedline including Embase and the Cost-Effectiveness Analysis (CEA) Registry were searched up to 7 May 2025. …”
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Assembly and Evaluation of a Confocal Microscopy Image Analysis Pipeline Useful in Revealing the Secrets of Plant-Fungal Interactions by Ashley C. Nelson, Gayan K. Kariyawasam, Nathan A. Wyatt, Jinling Li, Janine Haueisen, Eva H. Stukenbrock, Pawel Borowicz, Zhaohui Liu, Timothy L. Friesen

“…This pipeline relies on the use of KOH to remove the cutin layer of the leaf, increasing its permeability, allowing the different stains to penetrate and effectively bind to their targets, resulting in a consistent visualization of cellular structures. To expand the utility of this pipeline, we used the staining techniques in conjunction with machine learning to analyze fungal biomass through volume analysis, as well as quantifying nuclear breakdown, an early indicator of programmed cell death (PCD). …”
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FEASTS Combined with Interferometry. III. The Low Column Density H i Around M51 and Possibility of Turbulent-mixing Gas Accretion by Xuchen Lin, Jing Wang, Lister Staveley-Smith, Suoqing Ji, Dong Yang, Xinkai Chen, Fabian Walter, Hsiao-Wen Chen, Luis C. Ho, Peng Jiang, Nir Mandelker, Se-Heon Oh, Bo Peng, Céline Péroux, Zhijie Qu, Q. Daniel Wang

“…With simple models, we find that these low N _H _i structures could survive the background ultraviolet photoionization, but are susceptible to the thermal evaporation. …”
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Neurological and Olfactory Disturbances After General Anesthesia by Antonino Maniaci, Mario Lentini, Rosario Trombadore, Loris Gruppuso, Santo Milardi, Rosario Scrofani, Giuseppe Cuttone, Massimiliano Sorbello, Rodolfo Modica, Jerome R. Lechien, Paolo Boscolo-Rizzo, Daniele Salvatore Paternò, Luigi La Via

“…The olfactory system is particularly susceptible to anesthesia-induced neurotoxicity given its proximity to central nervous system structures and its role in sensory and cognitive processing. …”
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The COVID-19 pandemic and suicides in Warsaw = Pandemia COVID-19 a samobójstwa w Warszawie by Daniel D. Jońca, Cezary Orzechowski, Aleksandra Borowska-Solonynko, Karolina Hanusz, Paulina Konopka, Natalia Wolanowska, Aleksandra Zaremba

“… Aim of the study: The aim of this study was to analyze changes in the number of suicides, the methods of their occurrence, the age and gender structure of individuals committing suicide during the COVID-19 pandemic compared to the period before the pandemic. …”
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Intermittent fasting and body Composition: Insights from the Iranian National obesity registry (IRNOR) by Niloufar Abdollahpour, Najmeh Seifi, Mina Nosrati, Habibollah Esmaily, Pardis mohammadyfard, Mahsa Amarlou, Ali Ebrahimi Dabagh, Gordon A. Ferns, Maryam Alinezhad-Namaghi, Majid Ghayour-Mobarhan

“…Conclusions: The 5:2 IF may better preserve cellular structure and hydration balance, achieving clinically significant weight loss. …”
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Refining the link between obesity and heart failure: insights from GLP-1 receptor agonist trials and studies adopting direct adiposity measures by Nicola Riccardo Pugliese, Francesco Paneni, Domenico Tricò, Alessandra Violet Bacca, Nicolò De Biase, Hermann Dalpiaz, Alessandro Mengozzi, Agostino Virdis, Lorenzo Ghiadoni, Stefano Taddei, Reinhold Kreutz, Konstantinos Tsioufis, Stefano Masi

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The FinnBrain multimodal neonatal template and atlas collection by Jetro J. Tuulari, Aylin Rosberg, Elmo P. Pulli, Niloofar Hashempour, Elena Ukharova, Kristian Lidauer, Ashmeet Jolly, Silja Luotonen, Hilyatushalihah K. Audah, Elena Vartiainen, Wajiha Bano, Ilkka Suuronen, Isabella L. C. Mariani Wigley, Vladimir S. Fonov, D. Louis Collins, Harri Merisaari, Linnea Karlsson, Hasse Karlsson, John D. Lewis

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A DISCUSSÃO DAS RELAÇÕES ÉTNICO-RACIAIS NOS PROGRAMAS DE PÓS-GRADUAÇÃO EM EDUCAÇÃO DA REGIÃO NORDESTE(2009-2016) by Marcela Silva da Conceição, Wilma de Nazaré Baía Coelho

“…THE DISCUSSION OF ETHNIC RACIAL RELATIONS IN POSTGRADCATE PROGRAMS IN EDUCATION OF NORTHEAST REGION (2009-2016) Abstract This aticle aimstoknow thw discussion of the ethnic racial relations in postgraduate programs in education of northeast region (2009-2016) by means of the survey of techer intelectual production, structure analysis and organicity of the modus operandi oh the programs against the requirements of legal frameworks related to diversity and  specifically, the ethnic-racial relations. …”
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PSYCHOLOGICAL FACTORS OF THE FORMATION OF LEGAL AWARENESS OF STUDENTS OF HISTORICAL AND MEDICAL EDUCATION PROFILES by Dribas Svetlana, Semenov Konstantin

“…The purpose of the article is to determine psychological factors and compare the predictor structure of legal awareness among students of historical and medical education profiles. …”
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Focal Artefacts in Skeletal Scitigraphy by S. P. Mironov, E. I. Vasilenko, M. A. Karalkina, M. E. Bugriy, V. B. Sergienko

“…“Hot” spots (n = 11) mimicking metastatic lesion of bone structures were the results of the projection effect of extraosseous uptake of 99mTc-PyP (n = 9) or urinary contamination (n = 2). …”
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Identifying common disease trajectories of Alzheimer’s disease with electronic health recordsResearch in context by Mingzhou Fu, Sriram Sankararaman, Bogdan Pasaniuc, Keith Vossel, Timothy S. Chang

“…We employed dynamic time warping and k-means clustering to group similar trajectories, and network analyses to characterize their common structures. Causal inferences were explored using the Greedy Equivalence Search algorithm. …”
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Comparing variable neighbourhood search algorithms for the direct aperture optimisation in radiotherapy by Mauricio Moyano, Keiny Meza-Vasquez, Gonzalo Tello-Valenzuela, Nicolle Ojeda-Ortega, Carolina Lagos, Guillermo Cabrera-Guerrero

“…The VND algorithm is a deterministic variant of VNS that systematically explores different neighbourhood structures. This approach allows for a more thorough solution for space exploration while maintaining computational efficiency. …”
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The influence of provider payment mechanisms on TB service provider behavior in Indonesia: insights from National Health Insurance data and provider perspectives by Meghan O'Connell, Firdaus Hafidz, Sarah Saragih, Cheryl Cashin, Aditia Nugroho, Laurel Hatt, Yuli Farianti, Ackhmad Afflazier, Imran Pambudi

“…Qualitative analysis revealed that provider referral decisions were influenced by capitation-based payment structures, limited diagnostic tools, absence of dedicated TB rooms, lack of provider capacity, patient preferences, financial incentives favoring more profitable diseases, and providers’ social ties. …”
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Research Progress on the Improvement of Farmland Soil Quality by Green Manure by Yulong Wang, Aizhong Yu, Yongpan Shang, Pengfei Wang, Feng Wang, Bo Yin, Yalong Liu, Dongling Zhang, Qiang Chai

“…Specifically, it increases soil organic matter content, optimizes soil structure, enhances nutrient cycling, and improves microbial community composition and metabolic activity. …”
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Current sedation practices for non-invasive procedures in tertiary maternity and children’s hospitals in China: a 5-year update by Lu Wang, Bo Li, Ruidong Zhang, Yanhui Huang, Mazhong Zhang, Jijian Zheng

“…Questionnaires were sent to tertiary maternity and children’s hospitals nationwide through the WeChat Mini Program. The survey questioned the location and caseloads of hospitals providing sedation services, support facilities, contraindications, fasting practices, sedation regimens, monitoring practices, staff structure, certification requirements for sedation providers and quality control data.Results Procedural sedation for non-invasive procedures were provided in 88 of 114 hospitals. …”
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Neurovascular Restoration by Treadmill Exercise Attenuates Age-Related Cognitive Decline in Mice by Jae Min Lee, Da-Eun Sung, You Jung Choi, Seung Geun Yeo, Youn-Jung Kim

“…These results highlight the potential of exercise intervention as a non-pharmacological strategy for treating age-related neurodegenerative diseases by preserving vascular and BBB structures and reducing neuroinflammation.…”
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Life-history traits, pace of life and dispersal among and within five species of Trichogramma wasps: a comparative analysis by Guicharnaud, Chloé, Groussier, Géraldine, Beranger, Erwan, Lamy, Laurent, Vercken, Elodie, Dahirel, Maxime

“…We can define a pace-of-life axis structuring reproduction and development time as a continuum from less-fecund, longer-developing ″slow″ types to more-fecund, shorter-developing ″fast″ types. …”
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Short-term residential electricity consumption forecast considering the cumulative effect of temperature, dual decomposition technology and integrated deep learning by Lanlan Wang, Yong Lin, Tingting Song, Yuchun Chen, Kai Li, Junchao Ran

“…To meet this challenge, this paper designs the structure of this three-step residential electricity consumption forecasting. …”
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