Cohesin and condensin regulate chromosome topology and play an essential role in maintaining pluripotency in embryonic stem cells by Eui-Hwan Choi, Keun P. Kim

“…Cohesin maintains the cohesion of replicated sister chromatids until their separation at anaphase, whereas condensin facilitates the reorganization of chromosomes into a highly compact structure characteristic of mitosis. First, we found via ChIP-seq analysis that cohesins (SMC3, RAD21, and REC8) and condensin (SMC4) share DNA binding sites in close proximity and directly interact with the insulator protein CTCF. …”
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Building Professional Skills and Reducing Student Stress with Competency-based Education: An Exploratory Case Study by Ajay Rampersad, Noah Gentner

“…The results revealed five principal themes: (1) balancing flexibility with structure, (2) enhancing practical skills for career preparedness, (3) supportive learning through instructor and peer engagement, (4) navigating challenges in course design and workload, and (5) positive impact of mastery-based assessment. …”
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Factors Affecting Future Expectations of 12. Grade Students’ Preparation for Higher Education in Schools by Halime Güngör, Şefika Şule Erçetin

“…Activities aimed at structuring future expectations of students should be planned by school administration and the functionality of guidance services in schools should be increased. …”
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A Study of Prosocial Trends of Mothers with Children with Down Syndrome by Mambetalina Gaukhar, Aubakirova Zhanat, Medetbekova Anar, Burganova Roza

“…The results highlight a complex structure of prosociality, emphasizing individual differences in how these mothers respond to various social contexts. …”
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Crisis of the EU Eastern Policy by I. V. Bolgova

“…The article analyses key misperceptions of the actors involved in the complex of interactions in the region. The structure is complicated by the deepening and widening of Russia-lead Eurasian integration project. …”
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Aspects of the socio‐economic situation of disabled people in Russia by D.V. Nekipelova

“…The key aspects are reflected, including the legal basis for support, accessibility of the environment, education, employment, income level and structure of expenses of households consisting of disabled people. …”
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Order fulfillment planning with crowdsourcing integration by Xuejing Cao, Zhongmin Da, Xuefei Wang

“…To tackle the computational complexity, we develop an adaptive large neighborhood search algorithm tailored to exploit the problem structure and handle large-scale instances efficiently. …”
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Reliability analysis of passive residual heat removal system for large advanced pressurized water reactors by Tianrui Li, Xinkun Xiao, Guoqing Lu, Shikang Chen, Ronghua Chen, Wenxi Tian

“…Such comprehensive analysis contributes to ensuring the safe operation and advancement of nuclear power plants. The best-estimate program VITARS is used to analyze and calculate accident scenarios, with sensitivity analysis conducted based on preliminary thermal-hydraulic calculations to optimize parameter selection and simplify the response surface model structure, thereby streamlining the analysis process. …”
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Methodical foundations of the use of project-based technologies in teaching physics to students of technical specialties of higher education institutions by А.Б. Искакова, А.К. Каирбаева

“…The paper also proposes a general structure of the educational project for one semester. …”
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THE PROBLEMS OF PERFORMANCE MONITORING TO TAKLE THE TASKS OF THE AIRCRAFT CONTINUED AIRWORTHINESS by Yu. M. Chinyuchin

“…Not least important among the issues of resource and age structure monitoring to be considered is the need to improve the design of aircraft, taking into account preliminary technical and economic feasibility assessment of its modifications in the interests of the operator. …”
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Modelled impact of Tiny Targets on the distribution and abundance of riverine tsetse. by Glyn A Vale, John W Hargrove, Andrew Hope, Steve J Torr

“…Particular attention was given to demonstrating that the model could explain three matters of interest: (i) good control can be achieved despite the degradation of targets, (ii) local elimination of tsetse is impossible if invasion sources are not tackled, and (iii) with invasion and target degradation it is difficult to detect any effect of control on the age structure of the tsetse population.<h4>Conclusions</h4>Despite its simplifications, the model can assist planning and teaching, but allowance should be made for any complications due to seasonality and management challenges associated with greater scale.…”
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Substrate-analogous inhibitors exert antimalarial action by targeting the Plasmodium lactate transporter PfFNT at nanomolar scale. by André Golldack, Björn Henke, Bärbel Bergmann, Marie Wiechert, Holger Erler, Alexandra Blancke Soares, Tobias Spielmann, Eric Beitz

“…Resistance selection of cultured P. falciparum parasites with sub-lethal concentrations of MMV007839 produced a single nucleotide exchange in the PfFNT gene; this, and functional characterization of the resulting PfFNT G107S validated PfFNT as a novel antimalarial target. From quantitative structure function relations we established the compound binding mode and the pharmacophore. …”
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Design for Testability of Integrated Circuits and Project Protection Difficulties by E. Ph. Pevtsov, T. A. Demenkova, A. A. Shnyakin

“…It was proposed, inter alia: 1) to analyze the libraries of standard elements used in the project with full disclosure of their specifications; 2) to create nodes with the physical non-cloning function in the projects on the basis of the libraries of standard elements in models and analysis programs; 3) to analyze IP modules used in the project with the maximum disclosure of structure, methods and algorithms for providing test coverings; 4) to provide for the development in projects of special test kits and methods of their generation at the design stage of functions in order to detect malicious nodes and programs both within SoC cores and at the level of system buses; 5) to develop at the design stage and to apply during tests a technique of special hardware measurements of parameters of the manufactured circuits and analysis of their results, inter alia, according to measurements of delays in distribution of signals and/or buses current consumption.…”
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A comparative typology of verbal affixes in Riau-Malay and Sundanese by Azhary Tambusai, Khairina Nasution

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Preparing Future Teachers to Implement Distance Learning for Schoolchildren by M. V. Kuzmenko

“…The main directions of improving the graduates’ professional skills in the framework of the discipline “Distance learning technologies” and work program structure are given.Materials and methods. …”
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Utilization of Windu Shrimp Shell Waste from Malaka-NTT for Chitosan Synthesis: Characterization Study and Application Potential by Yohana Ivana Kedang, Ika Oktavianawati, Marselina Theresia Djue Tea

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Biosynthesis of silver nanoparticles from macroalgae Hormophysa triquetra and investigation of its antibacterial activity and mechanism against pathogenic bacteria by Shazia Bibi, Mohammed H. Abu-Dieyeh, Mohammad A. Al-Ghouti

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Effect of Acid Concentration on the Properties of Microcrystalline Cellulose from Pineapple Crown Leaf by Fitriani Fitriani, Sri Aprilia, Nasrul Arahman, Muhammad Roil Bilad

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THE ROLE OF VEGETABLE BREEDING AND MODERN RESEARCHES IN FOOD STABILITY by A. V. Soldatenko, O. N. Pishnaya

“…The vegetable production is one of the main factors for food security, as vegetables play an important role in the structure of nutrition. The Federal Scientific Vegetable Center creates competitive varieties and hybrids of vegetable crops that meet market requirements to meet the needs of domestic producers and thereby contributes to food security. …”
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Identification of Snowdrop Virus Y Occurred on Narcissus spp. in Korea by Minseok Kim, Minhui Kim, Sangmin Bak, Hak ju Kim, Hong-Kyu Lee, Jean Geung Min, Taegun Lim, Seungbin Baek, Minjoo Yang, Dong-Joo Min, Jin-Sung Hong, Hee-Seong Byun, Kyunghwa Nam, Su-Heon Lee

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