Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care by Clare E Palmer, Emily Marshall, Edward Millgate, Graham Warren, Michael Ewbank, Elisa Cooper, Samantha Lawes, Alastair Smith, Chris Hutchins-Joss, Jessica Young, Malika Bouazzaoui, Morad Margoum, Sandra Healey, Louise Marshall, Shaun Mehew, Ronan Cummins, Valentin Tablan, Ana Catarino, Andrew E Welchman, Andrew D Blackwell

“…ObjectiveThis study aims to evaluate the engagement, effectiveness, and safety of this structured, evidence-based digital program with human support for mild, moderate, and severe generalized anxiety. …”
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Immune predictors of response to immune checkpoint inhibitors in mismatch repair-deficient endometrial cancer by Etienne Rouleau, Ana Oaknin, Christophe Klein, Alexandra Leary, Sebastien Gouy, Patricia Pautier, Catherine Genestie, Amandine Maulard, Judith Michels, Marco de Bruyn, Emeline Colomba-Blameble, Annechien Plat, Juan Francisco Grau Bejar, Elisa Yaniz Galende, Qinghe Zeng, Audrey Le Formal, Elodie Edmond, Maëva Moreau

“…However not all responses and predictors of primary resistance are lacking.Methods We compared the immune tumor microenvironment of MMRd EC ICI-responders (Rs) and ICI non-responders (NRs), using spatial multiplexed immune profiling and unsupervised hierarchical clustering analysis.Results Overall, NRs exhibited drastically lower CD8+, absent terminally differentiated T cells, lack of mature tertiary lymphoid structures and dendritic cells, as well as loss of human leukocyte antigen class I. …”
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A Deep Learning-Based Probabilistic Approach for Non-Destructive Testing of Aircraft Components Using Laser Ultrasonic Data by Adriano Liso, Cosimo Patruno, Angelo Cardellicchio, Pierfrancesco Ardino, Nicola Gallo, Giuseppe del Prete, Valerio Dentico, Veronica Vespini, Sara Coppola, Pietro Ferraro, Vito Reno

“…Composite structures are commonly used in complex applications such as automotive and aerospace due to their high strength-to-weight ratio. …”
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SUBJECT-CENTRED CONTENT OF HIGHER EDUCATION AS A FACTOR IN THE EFFECTIVENESS OF PROFESSIONAL TRAINING OF A SPECIALIST by I. A. Leskova

“…The role of the teacher consists not in formal transfer of the factual material, but assistance with student independent designing and realization of productive capabilities of students. The two-tiered structure of information resource was described. This structure is caused by the unity of the principles of fundamental nature and professional orientation. …”
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The role of exosomes in the mechanisms of inflammation development in patients with cardiovascular pathology and the contribution to therapeutic potential of stem cells by P. F. Muzychenko, Zh. M. Minchenko, T. I. Havrylenko, V. A. Cherniak, S. V. Demidov, N. O. Ryzhkova, O. A. Pidhaina

“…There are also evidence of their impact on the structural and functional restoration of affected organs and blood vessels. …”
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Knowledge, attitudes, and practices of pregnant and postpartum women regarding stress urinary incontinence by Qin Dong, Shenxian Wan, Ruihua Wang, Sanshan Guo, Hong Shen, Ningjuan Wang, Wenting Cai, Luxi Cai, Wei Zhao

“…Findings revealed median scores: knowledge 20.00 [12.00, 28.00] (range: 0–44), attitudes 21.00 [19.75, 24.00] (range: 8–40), and practices 26.00 [22.00, 31.00] (range: 8–40). Structural equation modeling (SEM) showed knowledge directly influenced attitudes (β = -0.153, p < 0.001), while both knowledge (β = 0.522, p < 0.001) and attitudes (β = -0.128, p = 0.004) significantly impacted practices. …”
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Design and evaluation of a multi-epitope DNA vaccine against HPV16 by Lanfang Zhu, Xiangjie Cui, Zhiling Yan, Yufen Tao, Lei Shi, Xinwen Zhang, Yufeng Yao, Li Shi

“…Subsequently, through meticulous selection of T-cell epitopes and other necessary elements, a multi-epitope vaccine was constructed, exhibiting good immunogenic, physicochemical, and structural characteristics. Furthermore, in silico simulations showed that the vaccine not only interacted well with toll-like receptors (TLR2/TLR3/TLR4), but also induced a strong innate and adaptive immune response characterized by elevated Th1-type cytokines, such as interferon-gamma (IFN-γ) and interleukin-2 (IL2). …”
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A mechanism-based group psychotherapy approach to aggressive behavior (MAAP) in borderline personality disorder: a multicenter randomized controlled clinical trial by Christine Sigrist, Andreas Bechdolf, Katja Bertsch, Robin Bullenkamp, Martin Busse, Ute gr. Darrelmann, Astrid Dempfle, Martin Driessen, Thomas Frodl, Jan-Michael Kersting, Jessica Kesik, Burkhart Matzke, Corinne Neukel, Eva Niessen, Svenja Nückel, Viola Oertel, Frank Padberg, Alexandra Philipsen, Dorothee Pink, Andreas Reif, Matthias Reinhard, Carolin Steuwe, Larissa Wolkenstein, Sabine C. Herpertz, the MAAP Consortium

“…Discussion If proven superior, MAAP can be incorporated into standard psychiatric care, filling a critical gap in the current therapeutic landscape by offering a structured, cost-effective, and evidence-based treatment that directly targets the biobehavioral mechanisms underlying reactive aggression in BPD. …”
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Diagnóstico situacional del proceso enseñanza aprendizaje en posgrados de una unidad académica de Medicina. Una aproximación desde la percepción de docentes y profesionales estudia... by Sonia Arza Fernández, Jorge Ortiz, Miguel Franco, Jorge Flores

“…The data were obtained through semi-structured interviews and focus groups. The training programs were analyzed. …”
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DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines by Yu. V. Karpenko

“…The heterocyclization mechanism involves a nucleophilic attack by the amino group of hydrazide, thiol-thiourea tautomerism, ring closure, and structure aromatization. The most significant energy transitions are associated with the activation of the thiourea group and the formation of a new heterocyclic bond.…”
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In silico and in vivo Study of the Anti-Inflammatory Activity of Azomethine Derivatives of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 2-substituted 5,6,7,8-tetra... by Chiriapkin, A.S., Kodonidi, I.P., Abisalova, I.L., Diakova, I.N.

“…In silico prediction of anti-inflammatory activity was performed using the AutoDock 4.0 program. The virtual structures of the test compounds were constructed in HyperChem 8.0.4. …”
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Efficacy of neoadjuvant chemotherapy with docetaxel and cisplatin in patients with squamous cell carcinoma of the oral cavity at high risk of progression by S. I. Kutukova, Yu. V. Ivaskova, N. P. Beliak, G. A. Raskin, A. A. Varankina, A. I. Yaremenko, A. Ya. Razumova, A. O. Cheremnykh, M. F. Manna, R. V. Orlova

“…At the 1st stage of our study, we retrospectively analyzed the data of 98 patients and determine that the NACT for patients with oral cavity squamous cell carcinoma, with 3 or more factors of an unfavorable prognosis (peripheral blood parameters indicating the presence of systemic inflammation, reduced level of infiltration of tumor structures by CD8‑tumor infiltrating lymphocytes and low expression of programmed death-ligand 1 (PD-L1) on tumor and immune cells) significantly reduces the risk of death and disease progression: hazard ratio 0.33; 95 % confidence interval 0.13–0.86; p = 0.0231. …”
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Obstacles to effective communication between physical/occupational therapists and patients in the Saudi Arabian context: a cross-sectional study by Turki Aljuhani, Abrar M. Al-Mutairi, Abdullah Alfraih, Mohammed Alharbi, Turki AlAmri, Ali Alahmari, Abdulaziz Alotaibi, Mohammed Senitan

“…Conclusions Addressing communication barriers through targeted interventions, such as enhanced training, improved clinical structures, and advanced electronic health records, can improve patient satisfaction and treatment outcomes. …”
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A qualitative study on the experience of nurses in the health education for patients with ulcerative colitis based on the Ottawa decision support framework (基于渥太华决策支持框架的护士参与溃疡性结肠炎患... by LIANG Zhuolin (梁琢琳), LI Xumiao (李旭苗), WEI Rongsai (魏荣赛), LIU Jingying (刘璟莹), ZHANG Nan (张楠), MA Hongwen (马宏文)

“…Through purposive sampling, semi-structured interviews were conducted with 11 nurses from the Department of Gastroenterology. …”
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Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit by Wensan Wu, Jianli Wang, Chen Chen, Junqi Feng, Shuyi Zhang, An Shi, Jing Zhang, Xinyi He, Jiangchen Peng, Mingli Zhu

“…Alongside the software, a comprehensive quality improvement program: (1) multidisciplinary team collaboration; (2) data-driven QC; and (3) structured training. …”
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Level of non-adherence and associated factors among children on antiretroviral therapy in public hospitals of South Wollo Zone, Northeast Ethiopia by Endalk Birrie Wondifraw, Fekadeselassie Belege Getaneh, Muluken Amare, Setegn Mihret, Gebeyaw Biset, Birhanu Desu Tefera, Mulusew Zeleke, Fuad Ahmed, Ermias Sisay Chanie

“…Data were collected through face-to-face interviews, and reviewing patients’ documents using a structured checklist. The data were entered into Epi Data version 4.1 and analyzed using STATA 17. …”
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Self-screening practice of breast cancer and associated factors among female students in Ethiopian universities using the theory of planned behavior: a cross sectional study by Wudneh Simegn, Abdulwase Mohammed Seid, Gashaw Sisay Chanie, Liknaw Workie Limenh, Lamrot Yohannes, Teshome Demelash Bitew, Dagnew Getnet Adugna, Mihret Melese, Fikrie Tegen Kassie, Wondim Ayenew

“…The data were collected from January 30, 2022, to February 30, 2022, in Ethiopia. A structured, self-administered questionnaire was used. …”
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Awareness, attendance, and attitudes toward cervical cancer screening among HIV-positive Chinese women in Yunnan province: a cross-sectional study by Jiawei Hu, Rufei Duan, Hongyun Zhang, Xuelian Zhao, Aihui Wu, Le Li, Fanghui Zhao, Yong Zhang

“…An interviewer-administered semi-structured questionnaire was utilized to collect information on socio-demographic and behavioral characteristics, clinical characteristics related to HIV infection, awareness, attendance, and attitudes toward cervical cancer screening. …”
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Factors influencing self-efficacy of healthcare professionals towards end-of-life care in acute care settings in Palestine: a cross-sectional study by Mohammed F. Hayek, Baraa F. Shayeb, Jamila Jalal Yaseen, Issa Hashim Othman, Abdulrahman Afif Taha, Amal Bilal Mustafa Naddaf, Mohammed Mays Njedat, Ruba Sayed Saleh, Nizar B. Said, Ahmad Ayed, Loai M. Zabin, Eman Alshawish, Jamal Qaddumi, Imad Thultheen

“…Data were collected through a structured questionnaire that included demographic information and the validated Self-Efficacy in Palliative Care Scale (SEPC-S), covering communication and patient management domains. …”
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Training for Sustainable and Healthy Building for 2050 Part 2: Incorporation of New Knowledge and Dissemination for the Sustainability of the Trans-European Training Experience by Susana Lucas, Maria K. Koukou, Joanna Aleksiejuk-Gawron, Júlia Justino, Silviano Rafael, Antonios D. Livieratos, Nelson Carriço, John Konstantaras, Michail Gr. Vrachopoulos, Luís Coelho, Anna Chiara Benedetti, Cecilia Mazzoli, Annarita Ferrante, Rossano Scoccia, Jacopo Famiglietti, Tomasz Bakoń, Pavlos Tourou

“…The results of the BUILD2050 project demonstrate the potential of structured, trans-European training experiences to enhance professional competencies and support the transition to climate-neutral construction. …”
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