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51181
Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3’,5’-bisphosphate as a potent enzyme inhibitor
Published 2025-04-01“…Additionally, the crystal structure of human XRN1 was solved with pAp bound, demonstrating distinct interactions for the compound in the XRN1 active site. …”
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51182
Methodology for Estimating the Basic Reproductive Number of Current Variants of the Virus SARS-CoV-2
Published 2024-09-01“…In contrast to existing methods, the proposed method allows one to estimate R0 in the context of anti-epidemic measures, as well as by the dynamics of morbidity in a population with a collective immune status, taking into account the typical structure of the circulating SARS-CoV-2. Conclusion. …”
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51183
Visual analysis of drug research and development based on artificial intelligence
Published 2024-12-01“…AI-based virtual drug screening and structure-activity relationship analysis started early, while graph neural networks, pre-trained models (Transformer), interpretable AI technology, ChatGPT, and large language models were significantly highlighted in the last 3 years. …”
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51184
Pushing the limit to near real-time indoor LiDAR-based semantic segmentation
Published 2024-12-01“…While real-time semantic segmentation is already a reality for images, existing classification pipelines for LiDAR point clouds assume a pre-existing map which relies on data collected from accurate but heavy sensors. However, this approach is impractical for high-level task planning and autonomous exploration, which benefits from a rapid 3D structure understanding of the environment. …”
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51185
Eco-friendly composite hydrogel based on cellulose and bentonite for removal of lead (II): Kinetics and isotherm studies
Published 2025-03-01“…The composite hydrogel adsorbents' morphology, chemical composition, and structure were characterized using FE-SEM, EDX, FT-IR, and XRD. …”
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51186
A review of periostin in orthopedics
Published 2025-06-01“…Objective: This review explores periostin (POSTN), a matricellular protein integral to developmental physiological, and pathological processes, by examining its structure, function, and emerging roles in orthopedic and non-musculoskeletal pathologies. …”
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51187
Experimental Evaluation of Pet Food Waste as Biomass Fuel: Corrosion, Emissions, and Energy Potential
Published 2025-07-01“…A reduction of 0.015 Mg of CO<sub data-eusoft-scrollable-element="1">2</sub>eq per Mg of produced pet food was achieved. …”
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51188
Spatial coupling relationship between metamorphic core complex and gold deposits: Constraints from geophysical electromagnetics
Published 2024-10-01“…The fault-dip value on the left side is roughly 30°, while on the other side, the values significantly change from 30° to 75°, although they are in the same structure. Moreover, the controllable source audio MT method provides more detailed examinations of the right side fault. …”
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51189
A Modern View on the Treatment for Acute Calcium Channel Blocker Poisoning
Published 2024-09-01“…At the beginning of the 21st century, the structure of acute exotoxicoses changed, in particular, an increase in poisoning by drugs that mainly affect the cardiovascular system, including calcium channel blockers, was noted. …”
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51190
Land Use Changes and Cold-hot Spot Distribution in Hehuang Valley from 1980 to 2020
Published 2022-02-01“…Only by selecting research methods according to local conditions and focusing on different areas, can we optimize land use structure and realize the revitalization of urban and rural areas.…”
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51191
Psychometric Properties of the Spanish Versions of the Activity Restriction Scale
Published 2025-02-01“…The Activity Restriction Scale (ARS) has been widely used, with a two-factor structure obtained in previous studies. However, there is no validated instrument for this measure in Spanish. …”
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51192
Ambient Levels of Carbonyl Compounds and Ozone in a Golf Course in Ciudad Real, Spain: A ProtoPRED QSAR (Eco) Toxicity Evaluation
Published 2025-01-01“…The C<sub>1</sub>/C<sub>2</sub> and C<sub>2</sub>/C<sub>3</sub> ratios were also calculated to provide information about the main emissions sources of the analyzed carbonyl compounds, indicating that mainly anthropogenic sources contribute to air quality in the area. The data were further supported by Quantitative Structure-Activity Relationship (QSAR) models using the ProtoPRED online server, which employs in silico methods based on European Chemicals Agency (ECHA) regulations to assess the (eco)toxicity of the measured carbonyl compounds.…”
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51193
Calculation and Measurement of Near-Field RCS and Received Power Using a Downscaled Model of Precision-Guided Munition
Published 2025-07-01“…Meanwhile, the near-field RCS is analyzed based on the magnitude of the Poynting vector, obtained through High Frequency Structure Simulator (HFSS) shooting and bouncing ray plus (SBR+) simulation. …”
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51194
Insight into the composition and differentiation of endophytic microbial communities in kernels via 368 maize transcriptomes
Published 2025-05-01“…Diversity analysis revealed overall similarity in the community composition structure between tropical/subtropical (TST) and temperate (NSS) maize germplasm with apparent variations in community richness and abundance. …”
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51195
Characterization and Expression Analysis of PUB Gene Family Involved in Drought Stress Response in Trifoliate Orange (<i>Poncirus trifoliata</i>)
Published 2025-05-01“…Phylogenetic tree analysis indicated that 170 PUB proteins from trifoliate orange, <i>Arabidopsis thaliana</i>, and tomato were clustered into five subfamilies. Gene structure, conserved domain, and motif analyses revealed diverse exon–intron and motif organizations of <i>PtrPUB</i> genes, suggesting potential functional differentiation among <i>PtrPUBs</i>. …”
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51196
Radar Monitoring and Numerical Simulation Reveal the Impact of Underground Blasting Disturbance on Slope Stability
Published 2025-07-01“…Both elevation and lithological conditions significantly influence the intensity of vibration responses: high-elevation areas and structurally loose rock masses exhibit greater dynamic sensitivity. …”
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51197
Tissue engineering strategies for ocular regeneration; from bench to the bedside
Published 2024-10-01“…Millions globally suffer from visual impairment, complicating the management of eye diseases due to various ocular barriers. The eye's complex structure and the limitations of existing treatments have spurred interest in tissue engineering (TE) as a solution. …”
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51198
Discovery of Diffuse γ-Ray Emission in the Vicinity of G213.0-0.6: Supernova Remnant versus the Massive Star-forming Region
Published 2025-01-01“…SrcC, with a harder power-law photon spectrum, is located outside of the radio shell structure. All of them are spatially coincident with a dense molecular cloud (MC) in the velocity range of 35–54 km s ^−1 . …”
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51199
New insights from crystallography into the effect of Ni content on ductile-brittle transition temperature of 1000 MPa grade high-strength low-alloy steel
Published 2024-11-01“…The results indicated that increasing the Ni content can reduce the DBTT of HSLA steel and improve the impact toughness at low temperatures. EBSD data post-processing analysis revealed that the key reason for the increase in low-temperature toughness is the refinement of the microstructural crystallographic structure, specifically the significant increase in the boundary density of the block and packet. …”
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51200
In silico identification and functional annotation of universal stress protein (USP) gene family in Chenopodium quinoa
Published 2025-05-01“…The research conducted a genome-wide analysis of C. quinoa USP genes (CqUSPs). The gene structure, distribution of motifs, phylogenetic history, and duplication of CqUSPs were analysed. …”
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