A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein by Johannes Zeller, Karen S Cheung Tung Shing, Tracy L Nero, James D McFadyen, Guy Krippner, Balázs Bogner, Sheena Kreuzaler, Jurij Kiefer, Verena K Horner, David Braig, Habiba Danish, Sara Baratchi, Mark Fricke, Xiaowei Wang, Michel G Kather, Bernd Kammerer, Kevin J Woollard, Prerna Sharma, Craig J Morton, Geoffrey Pietersz, Michael W Parker, Karlheinz Peter, Steffen U Eisenhardt

“…We recently identified a novel mechanism that leads to a conformational change from the native, functionally relatively inert, pentameric CRP (pCRP) structure to a pentameric CRP intermediate (pCRP*) and ultimately to the monomeric CRP (mCRP) form, both exhibiting highly pro‐inflammatory effects. …”
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Impact of technical progress and fiscal support to agriculture on agricultural carbon emissions by Yamei Wang, Tao Zhang, Xi Wang, Bo Jiang, Xiuquan Huang

“…The sample was divided according to natural geographical environment, economic development level and agricultural production structure to study the regional heterogeneity from the spatial perspective. …”
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A Bioinert Hydrogel Framework for Precision 3D Cell Cultures: Advancing Automated High‐Content and High‐Throughput Drug Screening by Hyunsu Jeon, Tiago Thomaz Migliati Zanon, James Carpenter, Aliciana Ilias, Yamil Colón, Yichun Wang

“…The unique hexagonal‐close‐packed geometry of iCC structure enables HCHTS through conventional plate reader analysis and fluorescent microscopy assisted by house‐developed automated data processing algorithm. …”
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Continuous improvement towards environmental protection for pharmaceuticals: advancing a strategy for Europe by Sam Harrison, Catherine Barnett, Stephen Short, Cansu Uluseker, Patricia V. Silva, Maria D. Pavlaki, Sarah Roberts, Madalena Vieira, Stephen Lofts, Susana Loureiro, David J. Spurgeon

“…These opportunities include moving towards the risk assessment of mixtures, broadening the scope of effects testing to include non-conventional (e.g., behavioural) and chronic endpoints, making better use of predictive modelling such as Quantitative Structure–Activity Relationships (QSARs), and better accounting for environmental heterogeneity, such as the influence of temperature and especially pH on risk. …”
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An Approach for Detecting Faulty Lines in a Small-Current, Grounded System Using Learning Spiking Neural P Systems with NLMS by Yangheng Hu, Yijin Wu, Qiang Yang, Yang Liu, Shunli Wang, Jianping Dong, Xiaohua Zeng, Dapeng Zhang

“…To improve fault detection accuracy, we quantified the likelihood of a fault occurrence based on feature changes and expanded the feature space to higher dimensions using an ascending dimension structure. An adaptive learning mechanism was introduced to optimize the convergence and precision of the detection model. …”
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Key Drivers of ERP Implementation in Digital Transformation: Evidence from Austro-Ecuadorian by Juan Llivisaca-Villazhañay, Pablo Flores-Siguenza, Rodrigo Guamán, Cristian Urdiales, Ángel M. Gento-Municio

“…Quadrant analysis further emphasized the influence of IT structure and legacy systems on implementation characteristics, with cluster analysis identifying three distinct groups of companies based on their ERP strategies. …”
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Origin centric and part based pose decomposition for 3D human pose estimation by Zhijie Lin, Jinxin Yao, Juan Huang, Jingjing Chen, Yingying Xu, Lu Yang, Lei Zhao, Wei Xing

“…Skeleton Separation separates the 2D skeleton into several distinct parts, enabling the extraction of fine-grained local spatial features that accurately reflect the geometric structure of the human body. Secondly, we introduce the concept of a human skeleton Origin, which serves as a central hub to reconnect different parts through Skeleton Recombination. …”
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Assessing carbon emissions of facility agriculture involving photovoltaic greenhouses – insights from table grapes cultivation by Yichun Li, Shuyue Li, Yaru Luo, Xuecai Wang, Hengcheng Zhang, Yuquan W. Zhang, Shiren Song

“…Furthermore, this study suggests that for the broader facility agriculture, using low carbon structure materials would serve as the level to reduce carbon footprints.…”
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Psychometric properties of the Arabic version of the Young Schema Questionnaire Short Form-Version 3 (YSQ-S3) by Michel Sfeir, Álvaro Postigo, Feten Fekih-Romdhane, Covadonga González-Nuevo, Diana Malaeb, Souheil Hallit, Sahar Obeid

“…Confirmatory Factor Analysis showed a reasonable fit to the 5-domain structure of the questionnaire. All scores showed high McDonald’s omega values (0.91–0.97). …”
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Can the TLR-4-Mediated Signaling Pathway Be “A Key Inflammatory Promoter for Sporadic TAA”? by Giovanni Ruvolo, Calogera Pisano, Giuseppina Candore, Domenico Lio, Cesira Palmeri, Emiliano Maresi, Carmela R. Balistreri

“…Thoracic aorta shows with advancing age various changes and a progressive deterioration in structure and function. As a result, vascular remodeling (VR) and medial degeneration (MD) occur as pathological entities responsible principally for the sporadic TAA onset. …”
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Kultina VS. Quality of life as a factor of economic security of regions in Central Federal District for the period 2021–2022 by A. Yu. Fedorova, E. V. Weiss, M. V. Ilyukhina, V. S. Kultina

“…The survey conducted in the form of a questionnaire poll of citizens of the Central Federal District made it possible to form an idea of the structure of the quality of life of the population of the district. …”
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Validation of a Hebrew version of the Early Childhood Oral Health Impact Scale by Ofir Gaon, Lena Natapov, Diana Ram, Diana Ram, Shlomo Paul Zusman, Avia Fux-Noy, Avia Fux-Noy

“…Confirmatory factor analysis supported the questionnaire's two-factor structure and indicated a moderate fit to the data.ConclusionThe Hebrew version of the ECOHIS was found to be valid and reliable for measuring oral health-related quality of life in toddlers and preschool children in Israel.…”
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Synthesis, Characterization, and Antioxidant Activity of a New Copper(II)-imidazole Derivative Complex by Ariel Colaço de Oliveira, Ana Claudia Pedrozo da Silva, Antônio Gustavo Sampaio de Oliveira FIlho, Lilian Tatiani Dusman Tonin, André Luiz Tessaro, Felipe Nicolussi Pereira, Jonas de Arruda Leite Júnior, Rafael Block Samulewski

“…In this work, we present the synthesis and characterization of a complex formed by an imidazole-type ligand and copper(II). NMR data confirm the structure of ligand and that its interaction with copper(II) ions produces the complex [Cu(3NIMDZ-H)(OH2)5](ClO4)2 with a coordinated binding between copper(II) ion and nitrogen of the imidazole ring. …”
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The Diversity of Macrofungi in the Forests of Ningxia, Western China by Xiaojuan Deng, Minqi Li, Yucheng Dai, Xuetai Zhu, Xingfu Yan, Zhaojun Wei, Yuan Yuan

“…These observations unveil the diversity and community structure of macrofungi in Ningxia forests.…”
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Unravelling the effects of climate change on the soil-plant-atmosphere interactions: A critical review by Maria Nahin Oishy, Nigar Ahmmad Shemonty, Sadia Islam Fatema, Sadika Mahbub, Ebadunnahar Lukhna Mim, Maimuna Binte Hasan Raisa, Amit Hasan Anik

“…Key findings reveal that climate-induced disruptions such as altered precipitation, increased temperatures, and extreme weather events weaken soil structure, damage nutrient cycling, and modify plant growth, thereby threatening agricultural productivity and ecosystem stability. …”
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Hypothesis‐Driven Research on Multiple Stressors: An Analytical Framework for Stressor Interactions by Iris Madge Pimentel, Dania Albini, Arne J. Beermann, Florian Leese, Samuel J. Macaulay, Christoph D. Matthaei, James A. Orr, Jeremy J. Piggott, Ralf B. Schäfer

“…We illustrate the suggested approach with three case studies and validate statistical conclusions through data simulations. Post‐estimation inference has the potential to advance hypothesis‐driven research on stressor interactions by flexibly testing any a priori defined null model independent from regression model structure.…”
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Mitogenome characterization and phylogeny of Neohydatothrips gracilipes (Thripidae: Sericothripinae) by Abhishek Ghosh, Shash Pal, Vikas Kumar, Anindita Datta, Soumi Dey, Sandip Mandal, Dhriti Banerjee, Kaomud Tyagi

“…Most of the tRNAs showed a typical clover-leaf secondary structure except trnS1, trnV, which lack the DHU arm. …”
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Development of Semi-Automated Image-Based Analysis Tool for CBCT Evaluation of Alveolar Ridge Changes After Tooth Extraction by Anja Heselich, Joanna Śmieszek-Wilczewska, Louisa Boyo, Robert Sader, Shahram Ghanaati

“…Following tooth extraction, the bone structure is prone to atrophic changes. Alveolar ridge resorption can compromise subsequent implant treatment not only at the extraction site itself but also by affecting the bone support of adjacent teeth. …”
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Analysis and simulation of interception characteristics of broad-leaved forest canopy based on parameter optimization: Dianchi basin case by Qi Yi, Shengfang Hou, Xiaodong Dou, Yuting Gao, Zhongbin Li, Yiyan Liu

“…This study investigated the rainfall redistribution characteristics of three typical subtropical semi-humid evergreen broad-leaved forests in the Dianchi Basin of China. The model structure was improved by incorporating both canopy density and leaf area index (LAI) as indicators, and optimized the parameters using the Gauss-Newton algorithm, with appropriate threshold settings for absorption and additional interception. …”
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Research focus and trends of the association between gut microbiota and neuroinflammation by Shan Wu, Shan Wu, Nanjie Chen, Chuanchi Wang, Chuanchi Wang, Kwok-Fai So

“…Despite the large number of related studies, there is currently a lack of comprehensive analysis and prediction of these data to drive the field forward. This study aims to systematically analyze the clinical practices and research hotspots of the underlying mechanisms in this field using bibliometric and visualization methods, and to explore the future development pathways.MethodsCiteSpace, VOSviewer, GraphPad Prism and other software were used to analyze 1,404 studies on gut microbiota and neuroinflammation collected by the core of the Web of Science since 2000, to visually present the collaborative network between literatures, structure of authors and countries, co-occurrence of keywords, emerging reference literature, and research hotspots.ResultsFrom 2000 to 2024, the number of related papers on this topic showed an overall upward trend, and the annual citation peaked in 2020, with significant contributions from China and the United States. …”
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