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3021
The Relationship between Personality Structures and Moral Development: Mediating Role of Mind Reading in the Students of Farhangian University of Kerman
Published 2024-03-01“…Objective: The present investigation was conducted with the objective of exploring the relationship between personality structures, as conceptualized by the neo-approach, and moral development, taking into consideration the mediating role of mind reading. …”
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3022
Associations of Prenatal Socioeconomic Status and Childhood Working Memory: A Structural Equation Modeling Approach
Published 2025-04-01“…Study Design: We used data from a prospective birth cohort study in Mexico City, Mexico, with N = 515 children aged 6–9 years. …”
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3023
Comparative Analysis of Mitogenomes in Leafhopper Tribe Deltocephalini (Hemiptera: Cicadellidae: Deltocephalinae): Structural Conservatism and Phylogeny
Published 2024-12-01“…ABSTRACT Previous studies on the gene order and composition of leafhopper mitochondrial genomes have revealed a high level of conservation in overall genome structure. Some members of Deltocephalinae, the largest subfamily, exhibit tRNA gene rearrangements; however, few mitogenomes have been sequenced in this group and the degree of structural variation within tribes remains unclear. …”
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3024
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3025
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3026
Structural analysis of TRIM family PRYSPRY domains and its implications for E3-ligand design
Published 2025-12-01“…In addition, we mapped the locations of missense mutations in MID1 associated with X-linked Opitz syndrome, suggesting that some of these mutations impair the conformational stability of the protein. Taken together, our data provide intriguing insights into the structural and functional divergence of TRIM family PRYSPRY domains, their potential druggability and substrate recognition, and the challenges of ligand design.…”
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3027
Longitudinal structural MRI-based deep learning and radiomics features for predicting Alzheimer’s disease progression
Published 2025-08-01“…Early diagnosis is imperative for optimizing clinical management and selecting proper therapeutic interventions. Structural magnetic resonance imaging (MRI) markers have been widely investigated for predicting the conversion of MCI to AD, and recent advances in deep learning (DL) methods offer enhanced capabilities for identifying subtle neurodegenerative changes over time. …”
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3028
Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W
Published 2024-09-01“…The functional analysis was accompanied by structural investigation of PRKN p.R275W. We observed lower PRKN protein in fibroblasts with compound heterozygous p.R275W mutations. …”
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3029
Relationships between structural stigma, societal stigma, and minority stress among gender minority people
Published 2025-01-01“…We tested variables identified in the literature as measures of structural stigma inclusive of societal stigma (LGBT + Business Climate Index, state voting behaviors, and Google Trends search data), the most commonly used structural stigma variable (State Policy Environment Tally), and proxy variables (region, population density) for comparison. …”
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3030
Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses
Published 2025-06-01“…Disrupted in schizophrenia 1 (DISC1) is a pleiotropic scaffold protein that is postulated to comprise large disordered regions and four distinct structured segments with a high proportion of helical or coiled-coil fold. …”
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3031
Development and distribution characteristics of geohazards based on sedimentary-structural evolution in Xide County, southwest Sichuan
Published 2025-05-01“…The wide and gentle fold structures in red beds are the disaster-prone environment for landslide. …”
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3032
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3033
Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture
Published 2024-10-01“…Even though we observed model instability in our application of genomic SEM to high-dimensional data, jointly modeling the genetic architecture of complex traits and investigating multivariate genetic links across neuroimaging phenotypes offers new insights into the genetics of cortical structure and relationships to psychopathology.…”
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3034
Presence of Pain Shows Greater Effect than Tendon Structural Alignment During Landing Dynamics
Published 2025-02-01“…This study aims to investigate the relationship between tendon structure, presence of pain, and sex differences in landing kinematics and kinetics during countermovement jumps (CMJ) and tuck jump tests (TJT) in professional volleyball players. …”
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3035
Structural placental changes in women with intra-pregnancy novel coronavirus infection COVID-19 (review)
Published 2023-01-01“…In those that were excluded from the review, information about the clinical course of pregnancy and its outcome during novel coronavirus infection prevailed, or isolated cases of studying insignificant placental structural changes were discussed. Studies with a small number of observations were selected only in the case of the uniqueness of the published data, the absence of scientific papers where similar studies would have been conducted in larger sample.Results. …”
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3036
The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis
Published 2025-04-01“…Consequently, it is important to utilize relevant coordinate data for a comprehensive meta-analysis to identify the shared patterns of structural, functional, and multimodal alternations in TUD.MethodThe present study conducted a systematic retrieval of studies published on PubMed, Web of Science, and Scopus from January 1, 2010, to December 12, 2023, to identify studies on voxel-based morphometry (VBM) and resting-state functional magnetic resonance imaging (rs-fMRI) for TUD. …”
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3037
Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer
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3038
Pharmacological and structural characterization of vibostolimab, a novel anti-TIGIT blocking antibody for cancer immunotherapy
Published 2025-08-01“…The mouse surrogate anti-TIGIT antibodies were identified and used to extensively investigate the mechanism of action of anti-TIGIT antibodies as monotherapy or in combination with anti-programmed cell death protein-1 (PD-1) antibody in vivo by gene expression profiling and flow cytometry analyses with a mouse syngeneic tumor model.Results Structural analyses with solution NMR and X-ray crystallography revealed that vibostolimab binds the CC’C’’FG loop interface of TIGIT, completely competing for the binding site of CD155 with a larger coverage area than another anti-TIGIT antibody tiragolumab, consistent with surface plasmon resonance analysis, though mouse models with similar antibodies revealed no functional difference in antitumor efficacy. …”
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3039
Explaining the Effects of Geotourism on the Development of Entrepreneurship in City- Village Ghori-Ghalhe with Structural Equation Approach
Published 2017-05-01“…Finally, the results of final model of fitted structural equation for geotourism effect (as the independent variable of studdy) on entrepreneurship development (as dependent variable) among households of QuriQalhe showed that geotourism, at a confidence level of 99%, has a significant effect on the development of entrepreneurship and its indicators. …”
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3040
A whole-brain voxel-based analysis of structural abnormalities in PTSD: An ENIGMA-PGC study
Published 2025-01-01“…In the current study, we have conducted a voxel-based morphometry (VBM) meta-analysis using whole-brain statistical maps with neuroimaging data from the ENIGMA-PGC PTSD working group. Methods T1-weighted structural neuroimaging scans from 36 cohorts (PTSD n = 1309; controls n = 2198) were processed using a standardized VBM pipeline (ENIGMA-VBM tool). …”
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