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Structural model of the relationship between socioeconomic status and decision-making styles with the mediation of cognitive emotion regulation
Published 2022-12-01“…Methods: This descriptive-correlational study was a structural equation modeling. A total of 723 secondary school students in Tehran , in the academic year 2020-2021, were selected by random cluster sampling method. …”
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Mutational landscape of SARS-CoV-2 genome in Turkey and impact of mutations on spike protein structure.
Published 2021-01-01“…There was less surface hydrophilicity increase in the Asp614Gly mutation, which exhibits a more compact conformation around the ACE-2 receptor binding domain region, rendering the structure in a "down" conformation. Our genomic findings can help to model vaccination programs and protein modeling may lead to different approaches for COVID-19 treatment strategies.…”
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Decoding the mitogenome of rosemary (Salvia rosmarinus): insights into genome evolution, structural dynamics and prospects for mitochondrial engineering
Published 2025-04-01“…Synteny analysis of eight Lamiales species revealed extensive mitogenomic recombination and structural rearrangements. These findings highlight the dynamic nature of mitogenomes, offering insights into genome evolution and supporting future breeding programs to enhance the genetic diversity and adaptability of S. rosmarinus. …”
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A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer
Published 2025-08-01“…With the explosion of clinical NGS data and the concurrent availability of protein structures through the Protein Data Bank and protein models through programs such as AlphaFold, there exists an unprecedented opportunity to use structural information to help standardize NGS analysis with the overall goal of advancing personalized cancer therapy.MethodsUsing the Catalogue of Somatic Mutations in Cancer (COSMIC), the largest curated database of clinical cancer mutations, we mapped thousands of missense mutations in the kinase and juxtamembrane (JM) domains of 48 receptor tyrosine kinases (RTKs) onto structurally aligned kinase structures, then clustered known activating mutations along with VUSs based on proximity in three-dimensional structure. …”
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Optical genome mapping with whole genome sequencing identifies complex chromosomal structural variations in acute leukemia
Published 2025-04-01“…IntroductionChromosomal structural variations (SVs) play an important role in the formation of human cancers, including leukemias. …”
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Effect of structural characteristics on the stability of multi-weak rock slopes considering the spatial variability of geotechnical parameters
Published 2024-12-01“…Abstract The slope of open-pit mines is typically characterized by an interaction structure involving multiple weak layers, with these structural characteristics serving as key factors in determining rock slope stability. …”
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Exploring the genetic diversity and population structure of little-pod false flax (Camelina microcarpa: Brassicaceae) in Ukraine
Published 2025-04-01“…The observed high heterozygosity and complex population structure highlight the potential of C. microcarpa (especially the Southern Ukrainian population) to be used as a germplasm donor for C. sativa breeding programs. …”
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The Impact of Extracurricular Activities on Pre-Service Teacher Professional Development: A Structural Equation Modeling Study
Published 2025-07-01“…Data from 775 pre-service teachers (71.1% female) across multiple disciplines at a Turkish university were analyzed using structural equation modeling (χ<sup>2</sup>/df = 2.855, RMSEA = 0.049, CFI = 0.93, TLI = 0.92). …”
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Variability of the structure of correlations between the morphological and commercial traits of soybeans with different growth habit and branching characters
Published 2019-10-01“…A comparison of the level (R2, coefficient of determination) and structure of correlations in different years has shown that the deterioration of external conditions is followed by an increase in the strength of relationships (R2) between the traits and in the difference between correlation matrices’ structure. …”
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Surgical thyroid pathology in Crimea and Sevastopol: the way COVID-19 pandemic altered the frequency and structure of diseases
Published 2025-06-01“…To evaluate the impact of the COVID-19 pandemic on the structure of surgical thyroid pathology among the population of the Republic of Crimea and Sevastopol City in 2019–2024 through a retrospective data analysis.Patients and methods. …”
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Understanding and reducing delayed dental care for early childhood caries: a structural equation model approach
Published 2025-02-01“…The data in this study were analyzed using a variety of statistical tests, including the Kruskal-Wallis and Mann-Whitney tests, correlation analysis, multiple stepwise regression analysis, and structural equation modeling (SEM). Results The treatment delay score of early childhood caries was 36.77 ± 10.11, indicating that the state of early childhood caries was currently at a moderate level of delay. …”
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Deciphering the structural and dynamic effects of SHP2-E76 mutations: mechanistic insights into oncogenic activation
Published 2025-05-01“…These mutations disrupt the closed conformation, which normally keeps SHP2 in an inactive, auto-inhibited state, thereby enhancing phosphatase activity and activating SHP2, leading to a gain-of-function effect. However, the structural and functional implications of these disease-related mutants are not well elucidated. …”
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RNA editing-induced structural and functional adaptations of NAD9 in Triticum aestivum under drought stress
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