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  1. 7521
  2. 7522

    Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma by Lei Yang, Qing Zhou, Bo Zhang, Yi-Long Wu, Zhi-Hong Chen, Wen-zhao Zhong, Fen Wang, Yun-Ting He, Song Dong, Xue-Wu Wei, Wei-Dong Chen, Xiao-Rong Yang, Xue-Meng Shang

    Published 2022-02-01
    “…Backgrounds Immunotherapy is less effective in patients with epidermal growth factor receptor (EGFR) mutant non-small-cell lung cancer (NSCLC). Lower programmed cell death-ligand 1 (PD-L1) expression and tumor mutation burden (TMB) are reported to be the underlying mechanism. …”
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  3. 7523

    CHARACTERISTICS OF PSYCHOLOGICAL MATURITY AS A SOFT-SKILL OF A MODERN PERSONALIT by Mitchenko Kateryna

    Published 2024-06-01
    “…The aim of the article is to substantiate the essence and component structure of psychological maturity, and the set of soft skills as an integral part of an individual’s psychological maturity. …”
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  4. 7524

    Prevalence of chronic HCV infection in patients with type 2 diabetes mellitus in Russia by P. A. Beliy, K. R. Dudina, O. O. Znoyko, T. N. Markova, I. A. Morozova, N. P. Blokhina, E. A. Nurmukhametova, N. D. Yushchuk

    Published 2022-03-01
    “…The results of the study indicate the need to develop effective screening programs to detect active HCV infection in the group of patients with diabetes, as well as patients among them with severe hepatic fibrosis for the timely conduct of highly effective antiviral therapy, which will prevent poor outcomes in a separate perspective.…”
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  5. 7525

    DUAL EDUCATION AS A MEAN OF ENSURING PROPER QUALITY OF PROFESSIONAL TRAINING OF MATHEMATICS TEACHERS IN MODERN UKRAINE by Микола Працьовитий, Оксана Требенко, Олександр Школьний, Яніна Гончаренко

    Published 2022-09-01
    “…Solving the problem is envisaged through the implementation of a set of measures to modernize the structure, content, technologies and methods of training mathematics teachers, including the development and implementation of mutually beneficial partnership models between higher education institutions, employers and students, aimed at increasing the effectiveness of practical training of future teachers for the practical application of acquired knowledge and skills, their social and professional adaptation in the conditions of real professional activity. …”
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  6. 7526

    Symptom network analysis of pregnancy stress, depressive symptoms and quality of life: a cross-sectional study of pregnant women in Xinjiang, China, 2023–2024 by Sufeila Shalayiding, Weicui Meng, Xiaoting Wang, Bahedana Sailike, Ting Jiang

    Published 2025-07-01
    “…Methods From February 2023 to January 2024, a convenience sampling method was used to conduct a cross-sectional study of 1,349 pregnant women in a tertiary hospital in the Xinjiang Uygur Autonomous Region of China using the Patient Health Questionnaire Depressive Symptom Cluster and the Stress in Pregnancy and Health-Related Quality of Life Scale, to construct a network to perform network estimation, and to determine core nodes of the network structure based on the centrality indexes. Results Maternal pregnancy stress score (1.71 ± 0.55), depressive symptoms (15.36 ± 4.70), and quality of life had the highest social functioning score (74.45 ± 12.63) and the lowest physical functioning score (65.18 ± 26.75). …”
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  7. 7527

    Study on the Impact of Exclosures on the Physicochemical Properties of Rangeland Soil (Case Study: Northern Golestan Province, Sufikam Rangelands) by Rasool Khatibi, Mohsen Farahi

    Published 2024-09-01
    “…Among the remedial methods for degraded soils, increasing rangeland fertility and striving to improve soil structure stability, reducing livestock trampling through grazing restrictions, are highlighted. …”
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  8. 7528

    Orientaciones para crear patios activos en los centros escolares (Orientations to create active playgrounds in schools) by Mª Isabel Salas Sánchez, Josep Vidal-Conti

    Published 2020-07-01
    “…The interest of this study consists primarily in specifying the main aspects that should be considered when carrying out changes in the organization and/or structure of school playground areas. The objectives which this article pursues are mainly three.  1) to show evidence from different studies of the importance of recess time in schools.  2) to establish a "road map" to carry out transformations which would help to create active and dynamic spaces contributing, above all, to the improvement of students' health and therefore allowing the teaching staff to carry out the project or program of change (given the particularities and singularities of each one of the centers) and 3) to define some transversal proposals which can be introduced within this space and time. …”
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  9. 7529

    Productivity and ecological functions of naturally regrown pine forests of the Ukrainian Polissia by Petro Lakyda, Volodymyr Blyshchyk

    Published 2024-10-01
    “…Based on the indicators of basic wood density (341 kg·(m3)-1), the studied stands have a slightly lower density compared to other pine forests of the Ukrainian Polissia zone, which are characterized by high moisture content in wood at a young age, soil conditions (structure, mechanical composition, fertility), which has a significant impact on the formation of late wood, and, consequently, on its density. …”
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  10. 7530

    The effect of technology stress on knowledge concealment with the mediating role of job fatigue and moderating work autonomy by Hossein Jamali, Mehdi Kabirinaeini, Zeynab Elahi

    Published 2025-06-01
    “…These programs can include creating flexible work structures that allow employees to choose how to perform their tasks according to their work style and personal abilities. …”
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  11. 7531
  12. 7532

    Vaccine Hesitancy and Immunization Patterns in Central and Eastern Europe: Sociocultural, Economic, Political, and Digital Influences Across Seven Countries by Kurpas D, Stefanicka–Wojtas D, Soll–Morka A, Lomper K, Uchmanowicz B, Blahova B, Bredelytė A, Dumitra GG, Hudáčková V, Javorska K, Juhász Z, Manulik S, Mohos A, Skarbalius E, Tkachenko VI, Uchmanowicz I

    Published 2025-06-01
    “…Differences were influenced by healthcare system structure, public trust, exposure to misinformation, and digital communication strategies.Conclusion: Addressing vaccine hesitancy requires targeted, context-sensitive communication and digital literacy programs. …”
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  13. 7533
  14. 7534

    A Systematic Review of the Microfinance Literature: An ADO-TCM Framework Approach by Bahman Khodapanah, Mohammad Bashokouh Ajirlou, Fariba Mesri

    Published 2025-06-01
    “…This framework provides an in-depth analysis of the structure of relevant studies, encompassing predecessors, research decisions, research outcomes (ADO), utilized theories, study contexts, and research methods (TCM). …”
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  15. 7535
  16. 7536

    Lethal clinical outcome and chemotherapy and immunotherapy resistance in patients with urothelial carcinoma with MDM2 amplification or overexpression by Weijuan Zhang, Jiejie Xu, Hailong Liu, Yu Zhu, Zewei Wang, Han Zeng, Zhaopei Liu, Yuan Chang, Le Xu, Kaifeng Jin, Jingtong Xu, Xiaohe Su, Yawei Ding, Lingkai Zhang, Jiaxing Sun, Yuzhen Wu

    Published 2025-01-01
    “…In addition, UC with MDM2 amplification or overexpression was associated with an immuno-evasive contexture characterized by lower proportion of tertiary lymphoid structure infiltration, lower abundance of CD8+ T cells, IFN-γ+ cells, GZMB+ cells, and decreased expression of immune checkpoint molecules including programmed death-ligand 1 (PD-L1), programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4).Conclusions MDM2 amplification or overexpression defines a lethal subset of patients with UC with inferior prognosis and resistance to both platinum-based chemotherapy and immunotherapy irrespective of TP53/p53 status. …”
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  17. 7537

    Modeling the construction of an efficient customer club for the quantitative and qualitative development of increasing customers in the banking system by Ali Taher khani kojariha, Younos Vakil Alroaia

    Published 2024-09-01
    “…Data collection tools include semi-structured interviews and researcher-made questionnaires in the quantitative section. …”
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  18. 7538

    Distinct brain atrophy progression subtypes underlie phenoconversion in isolated REM sleep behaviour disorderResearch in context by Stephen Joza, Aline Delva, Christina Tremblay, Andrew Vo, Marie Filiatrault, Max Tweedale, Jean-François Gagnon, Ronald B. Postuma, Alain Dagher, Johannes Klein, Michele Hu, Petr Dusek, Stanislav Marecek, Zsoka Varga, John-Paul Taylor, John T. O'Brien, Michael Firbank, Alan Thomas, Paul C. Donaghy, Stéphane Lehéricy, Marie Vidailhet, Jean-Christophe Corvol, ICEBERG Study Group, Richard Camicioli, Howard Chertkow, Simon Lewis, Elie Matar, Kaylena A. Ehgoetz Martens, Lachlan Churchill, Michael Sommerauer, Sinah Röttgen, Per Borghammer, Karoline Knudsen, Allan K. Hansen, Dario Arnaldi, Beatrice Orso, Pietro Mattioli, Luca Roccatagliata, Oury Monchi, Shady Rahayel, Isabelle Arnulf, Samir Bekadar, Eve Benchetrit, Alexis Brice, Vanessa Brochard, Alizé Chalançon, Benoit Colsch, Florence Cormier-Dequaire, Jean-Christophe Corvol, Virginie Czernecki, Bertrand Degos, Cécile Delorme, Pauline Dodet, Carole Dongmo-Kenfack, Marie-Odile Habert, Farid Ichou, Jonas Ihle, Cécile Galléa, Rahul Gaurav, Marie-Alexandrine Glachant, Manon Gomes, David Grabli, Elodie Hainque, Laetitia Jeancolas, Christelle Laganot, Stéphane Lehéricy, Suzanne Lesage, Smaranda Leu-Semenescu, Richard Levy, Valentine Maheo, Graziella Mangone, Louise Laure Mariani, Aurelie Méneret, Poornima Menon, Fanny Mochel, Vincent Perlbarg, Dijana Petrovska, Fanny Pineau, Nadya Pyatigorskaya, Sophie Rivaud-Pechoux, Emmanuel Roze, Sara Sambin, Julie Socha, Arthur Tenenhaus, Romain Valabregue, Marie Vidailhet, Lydia Yahia-Cherif

    Published 2025-07-01
    “…Findings: SuStaIn identified two distinct subtypes of brain atrophy progression: 1) a “cortical-first” subtype, with atrophy beginning in the frontal lobes and involving the subcortical structures at later stages; and 2) a “subcortical-first” subtype, with atrophy beginning in the limbic areas and involving cortical structures at later stages. …”
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  19. 7539
  20. 7540

    ATF7IP inhibits Sorafenib-induced ferroptosis in hepatocellular carcinoma cells by inhibiting CYB5R2 transcription and stabilizing PARK7 protein by Yijie Su, Sirui Huang, Yang Duan, Liang Zhang, Shengyun Feng, Yingge Lv, Bei Lan, Chenghao Xuan

    Published 2025-09-01
    “…Ferroptosis, an iron-dependent form of programmed cell death, arises from the accumulation of lipid peroxides at toxic levels. …”
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