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6741
Application of The Cognitive-Technological Approach for Creating Online Courses on Digital Technologies for Teaching Staff
Published 2022-04-01“…From a theoretical point of view, the paper describes the key characteristics of the cognitive-technological approach that define consolidated requirements for the description of goals, content, structure and conditions for the implementation of additional professional educational programs for advanced training created on its basis. …”
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6742
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6743
Capacity enhancement on biosecurity for line supervisors working in commercial broiler farming Gujarat
Published 2025-10-01“…This study evaluated the socio-economic characteristics and biosecurity knowledge of 33 line supervisors through a one-day capacity-building training program. Pre- and post-training assessments, including structured questionnaires and Likert scales, were analyzed using descriptive statistics, and Factor Analysis of Mixed Data (FAMD) in R (v4.0.2). …”
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6744
Highly selective HPK1 inhibitor NDI-101150 mediates immune cell activation and robust antitumor responses, distinct from immune checkpoint blockade
Published 2025-07-01“…Genetic HPK1 kinase inactivation or knockout in mice leads to immune cell activation and tumor growth suppression, providing a strong rationale for targeting HPK1 kinase activity as an immuno-oncology therapy.Methods A structure-guided drug design approach was used to identify a highly potent and selective small molecule inhibitor of HPK1 kinase activity, NDI-101150. …”
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6745
Epidemiological Aspects of Monitoring the Sensitivity of <i>Staphylococcus aureus</i> Strains
Published 2025-04-01“…Conclusion. In the general structure of microorganisms of the hospital, Staphylococcus aureus strains prevailed (50%). …”
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6746
Epigenetic Modifiers to Treat Retinal Degenerative Diseases
Published 2025-06-01“…To extend our findings, we tested the hypothesis that this effect was due to altered chromatin structure by using a range of inhibitors of chromatin condensation to prevent photoreceptor degeneration in the rd10 mouse model. …”
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6747
Dysphagia in pediatric intensive care unit patients (review)
Published 2023-12-01“…The review analyzes the causes, features of diagnosis and treatment of dysphagia in pediatric patients with PIСS. 5 groups of causes in the structure of PIСS that can lead to the development of dysphagia were considered: infectious-trophic, vegetative-metabolic, neuromuscular, emotional-cognitivecomplications and decreased quality of life compared to the premorbid level. …”
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6748
First rangewide density estimate of the endemic and isolated Luangwa giraffe in Zambia
Published 2025-05-01“…However, sparse monitoring since the early 1900s has limited inferences about population size, structure, and range. To address this, we conducted the most spatially extensive and systematic survey to date of Luangwa giraffe across its distribution, extending survey effort 120 km south of their officially recognized extent. …”
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6749
Identification and Analysis of the Plasma Membrane H<sup>+</sup>-ATPase Gene Family in Cotton and Its Roles in Response to Salt Stress
Published 2024-12-01“…Chromosomal localization and collinearity analyses elucidated the distribution characteristics of this gene family within the cotton genomes. Gene structure and phylogenetic analyses demonstrated the conservation of this family across cotton species, whereas the examination of <i>cis</i>-acting elements in gene promoters highlighted their involvement in environmental stress and hormone response categories. …”
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6750
Informational and analytical support of planning processes of marketing actions in high-speed trains
Published 2018-02-01“…The functionality created on the basis of ACS “Express” is a flexible system of reports that are formed at the user's request, allowing you to view information on the structure of passenger traffic with varying degrees of detail for compiling programs to stimulate demand and analyze its effectiveness.…”
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6751
Clinical and epidemiological characteristic of chronic hepatitis C in the republic of Tyva
Published 2023-04-01“…The clinical profile of typical patients with chronic hepatitis C was established; whose share in the total structure of the examined was 38.4%. Conclusion: There is a tendency to reduce the incidence of chronic hepatitis C in the Republic of Tyva. …”
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6752
Grassland bird nest ecology and survival in upland habitat buffers near wooded edges
Published 2011-12-01“…We modeled nest survival in Program MARK as a function of time (yr and season), nest‐site, and local vegetation characteristics. …”
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6753
EPIDEMIOLOGICAL ASPECTS THE INCIDENCE OF CANCER OF THE KIDNEY AND BLADDER IN PRIMORSKY KRAI
Published 2017-03-01“…The incidence of bladder cancer in men tended to rise from the continental bioclimatic zone to the coast in all ecological zones mainly due to differences in the structure of the bioclimate between the coast and continental areas of Primorsky Krai. …”
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6754
DEVELOPMENT OF METHODS OF SIMULATION OF THE INTERACTION OF BIOLOGICALLY ACTIVE SUBSTANCES WITH THE ACTIVE CENTER OF ANGIOTENSIN-CONVERTING ENZYME
Published 2017-10-01“…The obtained technique can be used for studying the interaction of substances, similar in structure to lisinopril with the active center of the enzyme (ACE).…”
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6755
MITOCHONDRIAL DYSFUNCTION AS POSSIBLE CAUSE OF IMPAIRED FOLLICULAR DEVELOPMENT
Published 2016-06-01“…Mitochondria play leading role in senescence program realization. One of the early manifestations of this process is loss of reproductive function in female (menopause). …”
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6756
Genome-wide identification and expression profiling of the bZIP gene family in Chrysanthemum indicum and the functional analysis of CibZIP29 under cadmium stress
Published 2025-01-01“…Phylogenetic analysis grouped them into 12 subgroups, supported by conserved motifs, gene, and protein structure analyses. Tandem and segmental duplications were found to be key drivers of CibZIP gene family expansion, with Ka/Ks analysis indicating purifying selection of duplicated genes. …”
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6757
The Functions and Mechanisms of the Cohesin Complex in Regulating the Fate Determinations of Stem Cells
Published 2025-01-01“…By maintaining the chromatin loop structure, the cohesin complex is involved in DNA repair and gene transcription, which in turn controls the pluripotency, self-renewal, and differentiation of stem cells. …”
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6758
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6759
BioPipeline Creator—a user-friendly Java-based GUI for managing and customizing biological data pipelines
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6760