Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. by Wesley C Van Voorhis, John H Adams, Roberto Adelfio, Vida Ahyong, Myles H Akabas, Pietro Alano, Aintzane Alday, Yesmalie Alemán Resto, Aishah Alsibaee, Ainhoa Alzualde, Katherine T Andrews, Simon V Avery, Vicky M Avery, Lawrence Ayong, Mark Baker, Stephen Baker, Choukri Ben Mamoun, Sangeeta Bhatia, Quentin Bickle, Lotfi Bounaadja, Tana Bowling, Jürgen Bosch, Lauren E Boucher, Fabrice F Boyom, Jose Brea, Marian Brennan, Audrey Burton, Conor R Caffrey, Grazia Camarda, Manuela Carrasquilla, Dee Carter, Maria Belen Cassera, Ken Chih-Chien Cheng, Worathad Chindaudomsate, Anthony Chubb, Beatrice L Colon, Daisy D Colón-López, Yolanda Corbett, Gregory J Crowther, Noemi Cowan, Sarah D'Alessandro, Na Le Dang, Michael Delves, Joseph L DeRisi, Alan Y Du, Sandra Duffy, Shimaa Abd El-Salam El-Sayed, Michael T Ferdig, José A Fernández Robledo, David A Fidock, Isabelle Florent, Patrick V T Fokou, Ani Galstian, Francisco Javier Gamo, Suzanne Gokool, Ben Gold, Todd Golub, Gregory M Goldgof, Rajarshi Guha, W Armand Guiguemde, Nil Gural, R Kiplin Guy, Michael A E Hansen, Kirsten K Hanson, Andrew Hemphill, Rob Hooft van Huijsduijnen, Takaaki Horii, Paul Horrocks, Tyler B Hughes, Christopher Huston, Ikuo Igarashi, Katrin Ingram-Sieber, Maurice A Itoe, Ajit Jadhav, Amornrat Naranuntarat Jensen, Laran T Jensen, Laran T Jensen, Rays H Y Jiang, Annette Kaiser, Jennifer Keiser, Thomas Ketas, Sebastien Kicka, Sunyoung Kim, Kiaran Kirk, Vidya P Kumar, Dennis E Kyle, Maria Jose Lafuente, Scott Landfear, Nathan Lee, Sukjun Lee, Adele M Lehane, Fengwu Li, David Little, Liqiong Liu, Manuel Llinás, Maria I Loza, Aristea Lubar, Leonardo Lucantoni, Isabelle Lucet, Louis Maes, Dalu Mancama, Nuha R Mansour, Sandra March, Sheena McGowan, Iset Medina Vera, Stephan Meister, Luke Mercer, Jordi Mestres, Alvine N Mfopa, Raj N Misra, Seunghyun Moon, John P Moore, Francielly Morais Rodrigues da Costa, Joachim Müller, Arantza Muriana, Stephen Nakazawa Hewitt, Bakela Nare, Carl Nathan, Nathalie Narraidoo, Sujeevi Nawaratna, Kayode K Ojo, Diana Ortiz, Gordana Panic, George Papadatos, Silvia Parapini, Kailash Patra, Ngoc Pham, Sarah Prats, David M Plouffe, Sally-Ann Poulsen, Anupam Pradhan, Celia Quevedo, Ronald J Quinn, Christopher A Rice, Mohamed Abdo Rizk, Andrea Ruecker, Robert St Onge, Rafaela Salgado Ferreira, Jasmeet Samra, Natalie G Robinett, Ulrich Schlecht, Marjorie Schmitt, Filipe Silva Villela, Francesco Silvestrini, Robert Sinden, Dennis A Smith, Thierry Soldati, Andreas Spitzmüller, Serge Maximilian Stamm, David J Sullivan, William Sullivan, Sundari Suresh, Brian M Suzuki, Yo Suzuki, S Joshua Swamidass, Donatella Taramelli, Lauve R Y Tchokouaha, Anjo Theron, David Thomas, Kathryn F Tonissen, Simon Townson, Abhai K Tripathi, Valentin Trofimov, Kenneth O Udenze, Imran Ullah, Cindy Vallieres, Edgar Vigil, Joseph M Vinetz, Phat Voong Vinh, Hoan Vu, Nao-Aki Watanabe, Kate Weatherby, Pamela M White, Andrew F Wilks, Elizabeth A Winzeler, Edward Wojcik, Melanie Wree, Wesley Wu, Naoaki Yokoyama, Paul H A Zollo, Nada Abla, Benjamin Blasco, Jeremy Burrows, Benoît Laleu, Didier Leroy, Thomas Spangenberg, Timothy Wells, Paul A Willis

“…The Medicines for Malaria Venture Malaria Box is a collection of over 400 compounds representing families of structures identified in phenotypic screens of pharmaceutical and academic libraries against the Plasmodium falciparum malaria parasite. …”
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Особливості архітектурно-планувальної організації центрів розвитку молоді by Olena Troshkina, Alona Lupina

“…The results of the research can be used by the architect when designing space-planning solutions for youth spaces created in the context of structuring urban space, reorganizing obsolete buildings and adapting them to modern cultural trends, taking into account the interests of society, combining various activities into a single city program that functions as a full-fledged one. mechanism. …”
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Constitutive inflammation and epithelial-mesenchymal transition dictate sensitivity to nivolumab in CONFIRM: a placebo-controlled, randomised phase III trial by Dean A. Fennell, Kayleigh Hill, Min Zhang, Charlotte Poile, Sean Ewings, Essa Y. Baitei, Joanna Dzialo, Nada Nusrat, Jan Rogel, Daniel Faulkner, Christian Ottensmeier, Raffaele Califano, Gerard G. Hanna, Sarah Danson, Nicola Steele, Mavis Nye, Lucy Johnson, Kim Mallard, Joanne Lord, Calley Middleton, Peter Szlosarek, Sam Chan, Liz Darlison, Peter Wells-Jordan, Cathy Richards, James Harber, Aleksandra Bzura, Jake Spicer, Catrin Pritchard, Tamihiro Kamata, Jens C. Hahne, Maymun Jama, Edward J. Hollox, Jason F. Lester, Jin-Li Luo, Zisen Zhou, Hongji Yang, Huiyu Zhou, Astero Klampatsa, Gareth O. Griffiths

“…Non-synonymous and neoantigen mutation burden were no different between groups, however R-mesotheliomas were infiltrated with activated CD8+ T- and CD19+ B-lymphocytes, organised into tertiary lymphoid structures. B-cell infiltration correlated with pro-inflammatory chemokines including IL24 and CCL19. …”
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Debonding Analysis Model and Experimental Investigations on FRP Plates Reinforced SHCC Beams Under Three-point Bending by HU Jihong, SUN Mingqing, WANG Yingjun, CHEN Jianzhong, HUANG Wei

“…The results showed reasonable agreement with the experimental data, indicating that the approach can be applied to the analysis of this type of new civil engineering structure.…”
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Community-engaged curriculum development using racial justice and biomedical lenses to address COVID-19 vaccine hesitancy in black individuals with rheumatologic conditions by Eseosa Olive Osaghae, Greta Sirek, Tonya Roberson, Mia Chandler, Ariel Childs, Monica Crespo-Bosque, Gina Curry, Amar Dhand, Mary Dollear, Alice Eggleston, Nnenna Ezeh, Dieufort Fleurissaint, Denice Garrett, Gail Granville, Muriel Jean-Jacques, Elena Losina, Elena Losina, Holly Milaeger, Lutfiyya Muhammad, Mary Ann Nelson, Chisa Nosamiefan, Bisola Ojikutu, Bisola Ojikutu, Bisola Ojikutu, Neil Pillai, Mary Beth Son, Marie Jacques Toussaint, Ana Valle, Jessica N. Williams, Michael York, Karen Mancera-Cuevas, Candace H. Feldman, Candace H. Feldman, Rosalind Ramsey-Goldman

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概念為本跨領域課程發展之研究—以國際文憑組織中學階段課程為例 Concept-Based Interdisciplinary Curriculum Development in International Baccalaureate Schools in Taiwan– The International Baccalaureate Middle Years... by 洪麗卿 Li-Ching Hung, 劉美慧 Meihui Liu, 王俐蘋 Li-Ping Wang

“…This demonstrates the school’s pragmatic experiences in integrating the IB program into the national education system. The implications of this study were considered in combination with the practices of the two schools, and a concept-based interdisciplinary curriculum module was summarized to provide a reference for future implementation of such programs. …”
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First assessment of biofouling assemblages in the northern Red Sea, an important region for marine non-indigenous species transfer by Juan Sempere-Valverde, Juan Sempere-Valverde, Eva Aylagas, Vitaly Syomin, Vitaly Syomin, Marcos A. L. Teixeira, Glafira D. Kolbasova, Glafira D. Kolbasova, Sofía Ruiz-Velasco, Sahar Chebaane, Arthur Anker, João Curdia, Ronald Cadiz, Dylan M. Cottrell, Andrea Desiderato, Luiz F. Andrade, Chakkiath Paul Antony, Carolina Bocanegra-Castano, Matilde Marzucchi, Angelo Poliseno, Doaa Baker, Basmah Alabdulaziz, Flor Torres, Ameer A. Eweida, Ameer A. Eweida, Susana Carvalho, Susana Carvalho

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A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…At the heart of ART success is preimplantation genetic testing (PGT), which enables the detection of chromosomal anomalies, single-gene disorders, and structural rearrangements, enhancing embryo selection and mitigating genetic risk. …”
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On Signifiable Computability: Part II: An Axiomatization of Signifiable Computation and Debugger Theorems by Vladimir A. Kulyukin

“…In a previous article, we formalized the signification and reference of real numbers and showed that data structures representable as multidimensional matrices of discretely finite real numbers are signifiable. …”
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The effect of Plant Growth Promoting Rhizohacteria on activities of antioxidative enzymes, physiological characteristics and root growth of four chickpea (Cicer arietinum L.) culti... by Rahim Naseri, Abbas Soleymani Fard, Amir Mirzaei, Fereshteh Darabi, Amin Fathi

“…Therefore, the decline in growth and productivity due to these stress factors is associated with increased levels of ROS, which cause damage to cellular structures and macromolecules. In order to maintain or increase crop productivity it becomes necessary to evolve efficient low-cost technologies for abiotic stress management. …”
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Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa by Fredros Okumu, Sarah J. Moore, Prashanth Selvaraj, Arnon Houri Yafin, Elijah O. Juma, GloriaSalome G. Shirima, Silas Majambere, Andy Hardy, Bart G. J. Knols, Betwel J. Msugupakulya, Marceline Finda, Najat Kahamba, Edward Thomsen, Ayman Ahmed, Sarah Zohdy, Prosper Chaki, Peter DeChant, Kimberly Fornace, Nicodem Govella, Steven Gowelo, Emmanuel Hakizimana, Busiku Hamainza, Jasper N. Ijumba, William Jany, Hmooda Toto Kafy, Emmanuel W. Kaindoa, Lenson Kariuki, Samson Kiware, Eliningaya J. Kweka, Neil F. Lobo, Dulcisária Marrenjo, Damaris Matoke-Muhia, Charles Mbogo, Robert S. McCann, April Monroe, Bryson Alberto Ndenga, Halfan S. Ngowo, Eric Ochomo, Mercy Opiyo, Richard Reithinger, Chadwick Haadezu Sikaala, Allison Tatarsky, David Takudzwa, Fedra Trujillano, Ellie Sherrard-Smith

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Multiomics analysis reveals signatures of selection and loci associated with complex traits in pigs by Lei Liu, Guoqiang Yi, Yilong Yao, Yuwen Liu, Jiang Li, Yalan Yang, Mei Liu, Lingzhao Fang, Delin Mo, Longchao Zhang, Yonggang Liu, Yongchao Niu, Liyuan Wang, Xiaolu Qu, Zhangyuan Pan, Lei Wang, Muya Chen, Xinhao Fan, Yun Chen, Yongsheng Zhang, Xingzheng Li, Zhen Wang, Yijie Tang, Hetian Huang, Pengxiang Yuan, Yuying Liao, Xinjian Li, Zongjun Yin, Di Liu, Dongjie Zhang, Quanyong Zhou, Wangjun Wu, Jicai Jiang, Yahui Gao, George E. Liu, Lixian Wang, Yaosheng Chen, Kui Li, Martien A. M. Groenen, Zhonglin Tang

“…Using nine genomes—seven of which were newly generated, high‐quality de novo assembled genomes—and 1081 resequencing genomes, we built a pan‐genome and identified 134.24 Mb nonredundant nonreference sequences, 1099 novel protein‐coding genes, 187,927 structural variations (SVs) and 30,143,962 single‐nucleotide polymorphisms (SNPs). …”
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Designing a supply chain resilience assessment model with the approach of NDEA(case of study: government hospitals of Yazd province) by Mohsen Shafiei Nikabadi, Fereshteh Bahrami

“…Since the conventional envelopment analysis models cannot be used to measure the performance of units with a network structure, the network data envelopment analysis approach should be used (Pikani et al., 2022), which can evaluate the performance of units with a network structure such as two-stage, series, parallel, mixed, etc. …”
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The pattern of state organization in the new constitution of Lithuania: A third way between the presidential and parliamentary systems? by Andreas Hollstein

“…The author, while retaining the contact with this ruling and at the same time meeting the aim of the study—that is, to classify the structural pattern of state as noted in the Constitution, 1992—acknowledges: "provided that in this ruling the attention was drawn upon the question whether or not the resolution adopted by Seimas' majority on December 11, 1996, questioning the compatibility of the program of the Government of the Republic of Lithuania with the Constitution of Lithuania, the Constitutional Court ought to have turned its inquiry in such a way so that the background power balance of Lithuania’s state institutions be analyzed in detail. …”
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The proposed model of the body of knowledge of digital transformation for the Central Bank of the Islamic Republic of Iran by Samira Tahmasebi Ashtiani, Mohammad Hasanzadeh, Atefeh Sharif, Mostafa Amini

“…Purpose: A body of knowledge is a formal description of a field that includes a complete set of theories, methods, concepts in a structured way, and technologies. If we consider knowledge alone as the factor of individual superiority, the flow of knowledge is the factor of group superiority. …”
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exoALMA. XVII. Characterizing the Gas Dynamics around Dust Asymmetries by Lisa Wölfer, Marcelo Barraza-Alfaro, Richard Teague, Pietro Curone, Myriam Benisty, Misato Fukagawa, Jaehan Bae, Gianni Cataldi, Ian Czekala, Stefano Facchini, Daniele Fasano, Mario Flock, Maria Galloway-Sprietsma, Himanshi Garg, Cassandra Hall, Jane Huang, John D. Ilee, Andrés F. Izquierdo, Kazuhiro Kanagawa, Geoffroy Lesur, Cristiano Longarini, Ryan A. Loomis, Francois Menard, Anika Nath, Ryuta Orihara, Christophe Pinte, Daniel J. Price, Giovanni Rosotti, Jochen Stadler, Gaylor Wafflard-Fernandez, Andrew J. Winter, Hsi-Wei Yen, Tomohiro C. Yoshida, Brianna Zawadzki

“…While dust observations have revealed crescent structures in several disks, observations of their kinematic signatures are still lacking. …”
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Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context by Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu

“…We estimated familial aggregation/coaggregation using generalised estimating equations, heritability and genetic correlations using structural equation modelling. We also analysed ∼30,000 genotyped MDD cases from the UK Biobank and a Swedish cohort to explore which polygenic risk score (PRS) may predispose individuals to psychotic MDD. …”
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Sustainable forest management: success and challenges in Ethiopia by Rusha Begna Wakweya

“…However, more effective governance structures are needed to balance the goals of forest conservation and community development2. …”
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Direito e marxismo: a política de qualificação para trabalhadores desempregados na experiência do MTD em João Pessoa / Law and marxism: the qualification policy for unemployed work... by Ítalo Giovanni Fernandes Correia, Liziane Pinto Correia, José Victor Figueiredo de Lucena

“…Education still follows a rhythm of employability condition, now increased by the neoliberal context, in which the portfolios tend to be larger by efforts of the individuals who try to enter the job market through qualification or professionalisation programs. It is intended, thus, to review: some concepts of exploration by work and structural unemployment; the neoliberal discourse of employability that harms unemployed workers; the relationship between the theoretical basis and the extensionist experience that followed the Unemployed Workers Movement, in João Pessoa, during the conquest and participation in a public policy of qualification to combat unemployment and reflect its consequences<strong>.…”
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Impact of isotype on the mechanism of action of agonist anti-OX40 antibodies in cancer: implications for therapeutic combinations by Junping Jing, Laura Bover, C Ian Mockridge, Kerry L Cox, Mark S Cragg, Tatyana Inzhelevskaya, Chris A Penfold, Vikki English, Jane E Willoughby, Hong Shi, Peter J Morley, Heather Jackson, Roopa Srinivasan, Tom Murray, Axel Hoos, Paul Bojczuk, James Smothers, Niranjan Yanamandra, Lang Dou, Sabyasachi Bhattacharya, Laura Seestaller-Wehr, David Kilian, Kui S Voo, Mel John, Heather Niederer, Andrew J Shepherd, Laura Hook, Stephanie Hopley, Sara J Brett, Christopher Hopson, Elaine Paul, Stephen L Martin

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