E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsiveness by Alf Spitschak, Prabir Dhar, Krishna P. Singh, Rosaely Casalegno Garduño, Shailendra K. Gupta, Shailendra K. Gupta, Julio Vera, Luca Musella, Nico Murr, Anja Stoll, Brigitte M. Pützer, Brigitte M. Pützer

“…The transcription factor E2F1 is a key driver of tumor evolution and metastasis. To explore E2F1’s role in immune regulation in presence of aggressive melanoma cells, we established a coculture system and utilized transcriptome and cytokine arrays combined with bioinformatics and structural modeling. …”
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Global Trends and Hotspots in Non-Targeted Screening of Water Pollution Research: Bibliometric and Visual Analysis by Yitian Wu, Yewen Shi, Tianmin Gu, Xiushuai Du, Zhiyuan Du, Chi Zhang, Ke Sun, Yue Zhang, Xiaojing Guo, Shenghan Wang, Weiwei Zheng, Yi He, Wei Liu

“…By conducting a quantitative analysis and visualizing the publication trends, countries, authors, journals, and keywords, the present study identifies research hotspots, compositions, and paradigms within this field, trying to analyze the horizontal and vertical development trends and structural evolution of the research area. The research found that the application of NTS in water pollution studies has progressed through three phases: theoretical exploration, rapid development, and steady progress. …”
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Decoding the Future of Exoplanets: Asteroseismic Confirmation of Subgiant and Red Giant Hosts by Wen-Xu Lin, Sheng-Bang Qian, Li-Ying Zhu, Wen-Ping Liao, Fu-Xing Li, Xiang-Dong Shi, Lin-Jia Li, Er-Gang Zhao

“…These results are not only crucial for understanding the internal structures of evolved stars but also for predicting the eventual fate of their planetary companions, which may face engulfment as their host stars expand. …”
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Comparison on Hysteresis Loops and Dislocation Configurations in Fatigued Face-Centered Cubic Single Crystals by Zhibin Xing, Lingwei Kong, Lei Pang, Xu Liu, Kunyang Ma, Wenbo Wu, Peng Li

“…The aggregation and evolution of dislocations form different configurations, which are the preferred locations for fatigue crack initiation. …”
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High Power Semiconductor Technology Status and Progresses by Guoyou LIU, Yangang WANG, Xiang LI, Arthur SU, Kongjing LI, Songlin YANG

“…The evolution of modern Si based high power semiconductor devices and recent progress of novel device structures,as well as the status of wide bandgap semiconductor materials and devices were presented in this paper. …”
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L’horizon interdisciplinaire de la sociologie de l’environnement sur le terrain de l’agriculture alternative by René Audet

“…In order to better understand the opportunities brought by environmental sociology in interdisciplinary studies, this paper explores the foundation and evolution of the discipline. Taking the case of alternative agriculture as an example, it consists of a description of the state of the structuration of the environmental sociology field through the repartition of its approaches between the two tendencies of the socialization of the environmental problematic, and the naturalization of society. …”
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Educational contents and innovative competencies for training and research in technology industry by Mario Losasso

“…Today, the new educational challenges are facing emerging scenarios of the building industry digitalization, which contribute to determining structures of greater efficiency, linked to enabling technologies to manage intangible components and information.…”
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Conception de l’artefact, conception du collectif : dynamique d’un processus de conception ouvert et continu dans une communauté de développement de logiciels libres by Flore Barcellini

“…PEP processes are analyzed according a synchronic dimension (PEP-discussion focused) and a diachronic dimension (PEP evolution in the three interaction spaces). These analyses combine:- structural analyses of design and use oriented mailing-lists. …”
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Efficacy and tolerability of rufinamide in the treatment of epilepsy (experience of the Svt. Luka’s Institute of Child Neurology and Epilepsy) by K. Yu. Mukhin, O. A. Pylaeva, M. Yu. Bobylova, N. V. Freydkova, L. Yu. Glukhova, M. O. Abramov

“…Fifteen patients were diagnosed with LGS, whereas 16 patients were diagnosed with structural focal epilepsy with a phenocopy of LGS. Five patients had an evolution of West syndrome to LGS. …”
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Hints of Planet Formation Signatures in a Large-cavity Disk Studied in the AGE-PRO ALMA Large Program by Anibal Sierra, Laura M. Pérez, Carolina Agurto-Gangas, James Miley, Ke Zhang, Paola Pinilla, Ilaria Pascucci, Leon Trapman, Nicolas Kurtovic, Miguel Vioque, Dingshan Deng, Rossella Anania, John Carpenter, Lucas A. Cieza, Camilo González-Ruilova, Michiel Hogerheijde, Aleksandra Kuznetsova, Giovanni P. Rosotti, Dary A. Ruiz-Rodriguez, Kamber Schwarz, Benoît Tabone, Estephani E. TorresVillanueva

“…Resolved observations of the dust continuum emission (angular resolution of ∼150 mas, 20 au) show a ring-like structure with a peak at 0.″57 (75 au), a deep gap with a minimum at 0.″24 (31 au), an inner disk, a bridge connecting the inner disk and the outer ring, along with a spiral arm structure, and a tentative detection (to 3 σ ) of a compact emission at the center of the disk gap, with an estimated dust mass of ∼2.7−12.9 Lunar masses. …”
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Atacama Large Aperture Submillimeter Telescope (AtLAST) science: Gas and dust in nearby galaxies [version 2; peer review: 2 approved, 1 approved with reservations] by Pamela Klaassen, Mark Booth, Caroline Bot, Thomas Stanke, Claudia Cicone, Tony Mroczkowski, Doug Johnstone, Luca Di Mascolo, Minju Lee, Eelco van Kampen, Thomas Maccarone, Daizhong Liu, Matthew Smith, Francisca Kemper, Sven Wedemeyer, Amelie Saintonge, Alessandro Boselli, Enrique Lopez-Rodriguez, Bendix Hagedorn, Timothy A. Davis, Ann Mao, Akhil Lasrado, Frank Bigiel, Serena Viti, Paola Andreani, Melanie Chevance, Martin A. Cordiner, Alexander E. Thelen

“…This paper focuses on four themes which will particularly benefit from AtLAST: 1) the LMC and SMC, 2) extragalactic magnetic fields, 3) the physics and chemistry of the interstellar medium, and 4) star formation and galaxy evolution. With ~ 1000 − 2000 hour surveys each, AtLAST could deliver deep dust continuum maps of the entire LMC and SMC fields at parsec-scale resolution, high-resolution maps of the magnetic field structure, gas density, temperature and composition of the dense and diffuse ISM in ~ 100 nearby galaxies, as well as the first large-scale blind CO survey in the nearby Universe, delivering molecular gas masses for up to 106 galaxies (3 orders of magnitude more than current samples). …”
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La science politique en Amérique latine : une discipline pluridisciplinaire by Daniel Buquet

“…This article traces the main moments of Latin American political science in the light of the evolution of its institutional situation, particularly in university and academic structures, but also concerning the shifts in its centers of interest, the intellectual orientations that have prevailed within it, and the debates that have crossed it.…”
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Immunohistochemical and molecular evolutionary features of jejunoileal adenocarcinoma unveiled through comparative analysis with colorectal adenocarcinoma by Rei Ishikawa, Hidetaka Yamada, Hirotomo Saitsu, Ryosuke Miyazaki, Juri Takahashi, Rino Takinami, Satoshi Baba, Mitsuko Nakashima, Moriya Iwaizumi, Satoshi Osawa, Hideya Kawasaki, Yoshifumi Arai, Yoshiro Otsuki, Hiroshi Ogawa, Hiroki Mori, Fumihiko Tanioka, Shioto Suzuki, Kazuyo Yasuda, Makoto Suzuki, Haruhiko Sugimura, Kazuya Shinmura

“…Phylogenetic trees constructed for both pMMR-JIAC and dMMR-JIAC were more consistent with a “long trunk–short branches” structure than were those of CRAC, and the variant allele frequency peaks obtained for JIAC were higher than those of CRAC. …”
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De la littérature au jeu vidéo : le spectre de la narration interactive by Martin Ringot

“…My goal in this article is to show how a convergence between literature and video games can be found in the use of both medias of interactive narrative. The evolution of modern literature in the late twentieth century led to the resort of hypertextual structures. …”
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BETWEEN TRADITION AND MODERNITY: ETHNOGRAPHIC PERSPECTIVES ON MARRIAGE PRACTICES IN ETHIOPIA, NAMIBIA, ROMANIA AND SENEGAL by Corina Florina TĂTAR, Seedou Mukthar SONKO, Alphonse SAMBOU, Isobel MANUEL, Workie WULETAW, Marius Ioan TĂTAR

“…Employing ethnographic research methods, including field surveys, structured interviews, and literature reviews, the study highlights the pre-marital, marital, and post-marital rituals that define the cultural identity of these groups. …”
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Coupling Coordination Evaluation and Optimization of Water–Energy–Food System in the Yellow River Basin for Sustainable Development by Pengcheng Zhang, Yaoyao Fu, Boliang Lu, Hongbo Li, Yijie Qu, Haslindar Ibrahim, Jiaxuan Wang, Hao Ding, Shenglin Ma

“…This study focuses on the Yellow River Basin, conducting a comprehensive analysis of the system’s coupling mechanisms and influencing factors. A structured evaluation framework is established, integrating the entropy weight–TOPSIS method, the coupling coordination degree model, and spatial correlation analysis. …”
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Spatial Impact of Rural Landscape Pattern on Ecosystem Service in Hangzhou by Shuying WANG, Guofu YANG, Yiren XU, Bin XU

“…ObjectiveChanges in landscape pattern often bring about alterations in the structure, process, and function of ecosystem. In the context of rapid urbanization, drastic changes in land use/land cover (LULC) significantly disturb the structure and function of rural landscapes, leading to a series of ecological and environmental issues in rural areas such as farmland transformation, landscape fragmentation, and habitat degradation. …”
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Exploring Biodiversity Through Citizen Science: A Case Study of Green Roofs at the Calouste Gulbenkian Foundation Garden in Lisbon by Diogo Oliveira, Vitor Sousa, Patricia Tiago, Ana Leal, Ana Paula Falcão, Cristina Matos Silva

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Paschen–Back effect modulation of SO4 2- hydration in magnetized electrolyte toward dendrite-free Zn-ion batteries by Xiayan Yao, Zhi Wang, Jianwei Guo, Guoyu Qian, Hongchen Wang, Xuzhong Gong, Dong Wang

“…Abstract Tuning anionic solvation structures and dynamic processes at solid–liquid interfaces is critical yet challenging for stabilizing Zn metal negative electrodes in Zn-ion batteries, particularly due to the issue of dendrite formation and hydrogen evolution reaction. …”
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The First Complete Mitogenome Characterization and Phylogenetic Implications of <i>Elops machnata</i> (Teleostei: Elopiformes: Elopidae) by Jia-Yu Li, Xue-Fan Cui, Shu-He Chen, Yang Li, Shui-Yuan Zhang, Yuan-Feng Yang, Yi-Yang Li, Yu-Song Guo, Zhong-Duo Wang, Jian Liao

“…Amino acid composition analysis across 23 Elopomorpha species revealed consistently high leucine contents, and tRNA secondary structure prediction showed 21 tRNAs forming typical cloverleaf structures, except for <i>trnS1</i>(gct), which lacks the dihydrouridine (DHU) arm. …”
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