Where there is no nurse: an observational study of large-scale mentoring of auxiliary nurses to improve quality of care during childbirth at primary health centres in India by Swati Srivastava, Krishna D Rao, Nicole Warren, Kaveri Mayra, Aboli Gore, Aritra Das, Saifuddin Ahmed

“…This study examines if a long-term mentoring programme improved the ability of auxiliary nurse-midwives (ANMs), who function as paramedical community health workers, to provide quality care during childbirth, and how they compared with staff nurses.Design Quasi-experimental post-test with matched comparison group.Setting Primary health centres (PHC) in the state of Bihar, India; a total of 239 PHCs surveyed and matched analysis based on 190 (134 intervention and 56 comparison) facilities.Participants Analysis based on 335 ANMs (237 mentored and 98 comparison) and 42 staff nurses (28 mentored and 14 comparison).Intervention Mentoring for a duration of 6–9 months focused on nurses at PHCs to improve the quality of basic emergency obstetric and newborn care.Primary outcome measures Nurse ability to provide correct actions in managing cases of normal delivery, postpartum haemorrhage and neonatal resuscitation assessed using a combination of clinical vignettes and Objective Structured Clinical Examinations.Results Mentoring increased correct actions taken by ANMs to manage normal deliveries by 17.5 (95% CI 14.8 to 20.2), postpartum haemorrhage by 25.9 (95% CI 22.4 to 29.4) and neonatal resuscitation 28.4 (95% CI 23.2 to 33.7) percentage points. …”
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Major depression among pregnant women attending a tertiary teaching hospital in Northern Uganda assessed using DSM-V criteria by Jerom Okot, Henry Ochola, Nozuko P. Blasich, Michael Job Aeku, Pebalo Francis Pebolo, Felix Bongomin, Simple Ouma

“…Data were collected using a validated semi-structured questionnaire. MD was evaluated using DSM-V criteria and was defined as having (1) at least two weeks of either persistent low mood or excessive sadness, (2) plus additional symptoms from the MD diagnostic criterion A, for a total of at least five MD symptoms, and (3) the symptoms caused significant distress or problem and significantly altered behaviour or functionality. …”
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A higher burden of post-stroke depression and anxiety and their predictors among stroke survivors in the Amhara Regional State, Ethiopia, in 2024: a prospective multicenter study by Biruk Lelisa Eticha, Ermias Solomon Yalew, Destaw Marie Merawie, Samuel Teferi Chanie, Kaleb Assegid Demissie, Biruktawit Lelisa Eticha

“…Five trained physiotherapists conducted interviews, reviewed medical records, and took physical measurements using a pretested, semi-structured questionnaire to obtain high-quality data for analysis. …”
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The Intelligent Infectious Disease Active Surveillance and early warning system in China: An application of dengue prevention and control by Liangyu Kang, Jian Hu, Kangning Cai, Wenzhan Jing, Min Liu, Wannian Liang

“…This paper provides a detailed overview of the structure and functions of the Intelligent Infectious Disease Active Surveillance and Early Warning System in China, with a specific focus on its application in dengue prevention and control in Hainan Province from February to May 2024. …”
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The effect of preoperative oral carbohydrate administration on postoperative glucometabolic response, subjective well being and quality of life in patients undergoing colorectal su... by Murat Urkan, Cemile Celebi, Ulvi Mehmet Meral, Ikbal Cavdar

“…Postoperative albumin levels were significantly higher and CRP levels significantly lower in the intervention group at 24 h. The SF-36 physical functioning score was significantly higher in the intervention group compared to the control group (82.00 ± 11.81 vs 61.40 ± 16.17, p < 0.001). …”
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Identification of aging-related biomarkers for intervertebral disc degeneration in whole blood samples based on bioinformatics and machine learning by Zi-hang Li, Shi-pian Li, Shi-pian Li, Ya-hao Li, Yu-cheng Wang, Zhen-yu Tang, Kai-yang Xu, Xiao-rong Li, Zhen Tan, Jiao-yi Pan, Jin-tao Liu, Hong Jiang, Zhi-jia Ma, Yu-xiang Dai, Yu-xiang Dai, Yu-xiang Dai, Peng-fei Yu

“…IntroductionAging is characterized by gradual structural and functional changes in the body over time, with intervertebral disc degeneration (IVDD) representing a key manifestation of spinal aging and a major contributor to low back pain (LBP).MethodsThis study utilized bioinformatics and machine learning approaches to identify aging-related biomarkers associated with IVDD in whole blood samples. …”
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Limiting serine availability during tumor progression promotes muscle wasting in cancer cachexia by Erica Pranzini, Livio Muccillo, Ilaria Nesi, Alice Santi, Caterina Mancini, Giulia Lori, Massimo Genovese, Tiziano Lottini, Giuseppina Comito, Anna Caselli, Annarosa Arcangeli, Lina Sabatino, Vittorio Colantuoni, Maria Letizia Taddei, Paolo Cirri, Paolo Paoli

“…Serine is the second most-consumed amino acid (AA) by cancer cells and has emerged to be strictly necessary to preserve skeletal muscle structure and functionality. Here, we demonstrate that decreased serine availability during tumor progression promotes myotubes diameter reduction in vitro and induces muscle wasting in in vivo mice models. …”
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Effect of bacteriocin-producing Pediococcus acidilactici strains on the immune system and intestinal flora of normal mice by Yiteng Qiao, Zhichang Qiu, Fengwei Tian, Leilei Yu, Jianxin Zhao, Hao Zhang, Qixiao Zhai, Wei Chen

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A clinical trial on the effectiveness of MERITA group therapy for emotion regulation and interpersonal skills in children and adolescents exposed to abuse and domestic violence by Mar Alvarez-Segura, Anna Butjosa, María Angeles Navarro, Eva María Ortiz-Jiménez, Teresa Richart, Paola De Rose, Veronica Sperandini, Fernando Lacasa

“…TAU) in traumatic, depressive, and anxious symptomatology, emotional dysregulation, interpersonal difficulties, externalizing and internalizing symptoms, somatic complaints, prosocial behavior, attachment, and family functioning. A total of 128 WDV patients were required (64 for the intervention group and 64 for the control group) from the Child and Adolescent Mental Health Center (Cornellà de Llobregat, Barcelona, Spain) of the Hospital Sant Joan de Déu. …”
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A <i>tetra</i>-<i>ortho</i>-Chlorinated Azobenzene Molecule for Visible-Light Photon Energy Conversion and Storage by Shuxin Tang, Yating Zhang, Jun Xia, Jing Qi, Fan Tang, Fei Zhai, Liqi Dong

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Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness by Martina Cacciatore, Francesca Giulia Magnani, Filippo Barbadoro, Camilla Ippoliti, Mario Stanziano, Mario Stanziano, Letizia Clementi, Anna Nigri, Lorenzo Nanetti, Silvia Marino, Fabio La Porta, Lucia Francesca Lucca, Francesco Prada, Francesco Prada, Matilde Leonardi

“…IntroductionConsciousness relies on both cortical and subcortical structures and their feedforward and feedback pathways. …”
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Cost-effectiveness of an 8-week supervised education and exercise therapy programme for knee and hip osteoarthritis: a pre–post analysis of 16 255 patients participating in Good Li... by Ewa M Roos, Søren T Skou, Rikke Ibsen, Jakob Kjellberg, Dorte T Grønne

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Characterization of Load Components in Resistance Training Programs for Kidney Transplant Recipients: A Scoping Review by Jhonatan C. Peña, Lilibeth Sánchez-Guette, Camilo Lombo, Edith Pinto, Carlos Collazos, Blanca Tovar, Diego A. Bonilla, Luis A. Cardozo, Luis Andres Tellez

“…Resistance training (RT) has been shown to produce beneficial effects, including on quality of life, renal function, physical fitness, and survival rates in kidney transplant for 24 recipients. …”
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Enterobacteriaceae and Bacteroidaceae provide resistance to travel-associated intestinal colonization by multi-drug resistant Escherichia coli by Matthew Davies, Gianluca Galazzo, Jarne M. van Hattem, Maris S. Arcilla, Damian C. Melles, Menno D. de Jong, Constance Schultsz, Petra Wolffs, Alan McNally, Willem van Schaik, John Penders

“…Neither the microbial richness (Chao1), diversity (effective Shannon) and community structure (Bray–Curtis dissimilarity) in pretravel samples nor the longitudinal change of these metrics during travel were predictive for ESBL-E acquisition. …”
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Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…A physicochemical, structural, and molecular comparison was conducted with exosomes (EXOs) released from the same batch of cells. …”
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MODULATION AS A MULTIMODAL TRANSLATION STRATEGY OF GRAPHIC NOVEL PERSEPOLIS BY M. SATRAPI by Anna V. Khodorenko

“…It shows that these techniques function within the broader framework of the modulation strategy, facilitating the pragmatic adaptation of the original text. …”
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Effectiveness of epidural steroid injections in managing lumbar radicular pain: A prospective study by Bhagat SIngh, Bharath Vadivelkumar, Prem Kumar Kothimbakkam, Vijayashankar Murugesan, Thirumal Ranganathan

“…The study demonstrates meaningful functional improvements and pain relief in the majority of patients, supporting ESIs as a valuable non-surgical intervention in clinical practice.…”
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Individualized transcranial temporal interference stimulation (tTIS) for cognitive impairments and negative symptoms in patients with schizophrenia: a study protocol for a randomiz... by Shuzhe Wang, Junhao Chen, Linxuan Wang, Jingxuan Liu, Lijun Wang, Wenjie Sun, Shen Li, Jie Li

“…Transcranial temporal interference stimulation (tTIS) is a novel, non-invasive brain stimulation technique that enables targeted modulation of deep brain structures with high spatial specificity. While tTIS has shown promise in preliminary studies of other neuropsychiatric conditions, its clinical utility in SCZ has not been established. …”
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Landscape Analysis and Assessment of Ecosystem Stability Based on Land Use and Multitemporal Remote Sensing: A Case Study of the Zhungeer Open-Pit Coal Mining Area by Yinli Bi, Tao Liu, Yanru Pei, Xiao Wang, Xinpeng Du

“…Following rehabilitation efforts, the landscape patch density, landscape separation, and landscape fragmentation in the Zhungeer open-pit coal mining area exhibited a declining trend, leading to a more uniform distribution of landscape patches and improved structural balance. By 2020, the adaptability index had risen to 0.35836, achieving 93.69% of the restoration level observed prior to mining operations in 1985, thus indicating an improvement in ecosystem stability and the restoration of ecological functions, although rehabilitation efforts display a temporal lag of 10 to 15 years. …”
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End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence by Wojciech Ciezobka, Joan Falco-Roget, Cemal Koba, Alessandro Crimi

“…Stroke is one of the leading causes of mortality and morbidity worldwide, and it demands precise diagnostic tools for timely intervention and improved patient outcomes. Neuroimaging data, with their rich structural and functional information, provide a fertile ground for biomarker discovery. …”
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