Effectiveness Of The Core Activation And Rehabilitation Exercises For Knee Osteoarthritis - Program (CARE -KOA©) Among Patients Diagnosed With Knee Osteoarthritis. [version 4; peer... by Saurabh Mehta, Ajit R. Mahale, Dias Tina Thomas, Prajwal Prabhudev Mane, Atmananda S Hegde, Charu Eapen

“…Recent research highlights the role of kinetic chain and core muscle involvement in disease progression, yet evidence for structured core activation protocols such as CARE-KOA© remains limited.This study addresses this gap by evaluating the effectiveness of CARE-KOA©, which specifically targets proximal stability and biomechanical deficits in KOA, aiming to enhance pain, function, and core endurance beyond conventional approaches. …”
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Inulin promotes appetite in mice by regulating the gut microbiota under conditions of rapid entry to the plateau. by Xiaoli Li, Shengcai Wu, Xiaonan Chen, Jian Chen, Bao Liu, Xianshuai Liang

“…This study compared the structural and functional characteristics of food intake, body weight changes, serum appetite hormone levels, and intestinal flora of mice in different doses of inulin intervention and control groups in two distinct environments: plains and the rush-into plateau. …”
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Spider Cage Therapy's Impact on GMFM-88 in Iraqi Infants with Cerebral Palsy in Two Rehabilitation Centers by Nizar Jassim, Amenah Mohammed, Hayder Abbood, Naeem Almashhadani

“…The intervention consisted of structured sessions within the spider cage aimed at improving motor function. …”
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Multiparametric MRI for the improved diagnostic accuracy of Alzheimer's disease and mild cognitive impairment: Research protocol of a case-control study design. by Albert Dayor Piersson, Buhari Ibrahim, Subapriya Suppiah, Mazlyfarina Mohamad, Hasyma Abu Hassan, Nur Farhayu Omar, Mohd Izuan Ibrahim, Ahmad Nazlim Yusoff, Normala Ibrahim, M Iqbal Saripan, Rizah Mazzuin Razali

“…Magnetic resonance imaging (MRI) using structural MRI (sMRI), functional MRI (fMRI), diffusion tensor imaging (DTI), and magnetic resonance spectroscopy (1H-MRS) performed alone is inadequate. …”
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A network perspective on cognition in individuals with Parkinson's disease by Daniel Scharfenberg, Elke Kalbe, Monika Balzer‐Geldsetzer, Daniela Berg, Rüdiger Hilker‐Roggendorf, Jan Kassubek, Inga Liepelt‐Scarfone, Brit Mollenhauer, Kathrin Reetz, Oliver Riedel, Sandra Roeske, Jörg B. Schulz, Alexander Storch, Claudia Trenkwalder, Karsten Witt, Hans‐Ulrich Wittchen, Richard Dodel, Anja Ophey

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“Proteinjury”: a universal pathological mechanism mediated by cerebrospinal fluid in neurodegeneration and trauma by Vladimir F. Lazarev, Bashar A. Alhasan, Irina V. Guzhova, Boris A. Margulis

“…This review explores the mechanisms underlying the formation of pathogenic protein complexes in CSF, the diagnostic potential of CSF protein biomarkers, and the prospects for rehabilitation therapies aimed at preventing secondary damage mediated by pathogenic protein structures in CSF. Based on the findings discussed in this review, we conclude that proteinjury represents a universal and critical mechanism in the progression of various neurodegenerative disorders, and a deeper understanding of this phenomenon may provide new insights for the development of targeted interventions to improve clinical outcomes.…”
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Dysbiosis of Gut Microbiota in Ankylosing Spondylitis Patients by Yang L, Wang K, Liu B, Chen T, Ma T, Cui Z, Zhang D, Zhang S, Liu X, Shen J, Lu H

“…Bioinformatic processing and statistical analysis were performed to assess the microbial community structure, diversity, and function.Results: The study revealed significant differences in gut microbiota composition between AS patients and healthy controls. …”
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A család ereje: A házasságban élés és a nagycsaládos lét kapcsolata a jóllét különböző mutatóival by Andrea FERENCZI, Zsuzsanna KÖVI, Veronika MÉSZÁROS

“…CONCLUSIONS – The findings highlight the complex interplay between gratitude and family as well as religious background. The protective function of dispositional gratitude may be especially relevant for the development of psychological prevention and intervention programmes, as it can contribute both to the enhancement of perceived social support and the maintenance of subjective well-being. …”
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Navigating loneliness: the interplay of social relationships and coping skills by Eric Cornelis Schoenmakers, Tina ten Bruggencate

“…The research question is ‘what do emerging adults need in order to not feel lonely?’. Semi-structured interviews with university students from the Netherlands (N = 29; 20–26 years) were conducted between November 2021 and February 2022. …”
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Evaluation of the factors that impact upper limb coordination in children with cerebral palsy: A narrative review by Sara Di Benedetto, Andrea Battaglino, Vanesa Abuín-Porras, Eleuterio A. Sánchez-Romero, Raquel Cantero-Tellez, Kristin Valdes, Jorge Hugo Villafañe

“…Conclusion: Factors that include body structures and functions, time and age of the child, the relationship between factors, and assessment tools can influence the assessment and presentation of upper limb coordination in children with CP. …”
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Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics by Ji-Peng Liu, Long-Teng Tu, Ke-Zhen Yang, Yin-Yin Li, Yu Gong, Bing-Xuan Han, Chuan Liu, Tian-Qi Xia, Yu Liu, Xiao-Min Hao, Bing-Nan Yue, Jing Zhang, Bing-Hui Wang, Gui-Rong Luo, Qing-Guo Liu, Meng Xu

“…EA and MA influence the composition of intestinal microbiota in SHRs, aligning the microbial structure more closely with that of the WKY group. …”
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Intervención estatal, transformaciones en los vínculos con el sector privado y crecimiento económico sectorial. El caso del sector de Software y Servicios Informáticos de la ciudad... by CARINA BORRASTERO

“…We argue that the type of intervention undertaken by the Provincial Government, in its close association with a particularly dynamic economic sector, produced important changes at the structural level of the State, its specific functions, the nature of its relationship with the private sector and ways to institutionalize such links, progressively acquired a ‘structural’ character. …”
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Exploring Therapists’ Approaches to Treating Eating Disorders to Inform User-Centric App Design: Web-Based Interview Study by Pamela Carien Thomas, Pippa Bark, Sarah Rowe

“…Barriers to recommendation include patient safety, data privacy, and a perception that they may not be effective. Many existing interventions have limited functionality or do not differ much from manual cognitive behavioral therapy (CBT) or self-help books, which may not adequately support the therapeutic process or sustain user engagement. …”
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Exploring prevention and control mechanisms of youth substance use: a case of North Wollo and Waghimra, Northeast Ethiopia by Sindew Asmare Wedi, Biruk Beletew Abate, Biruk Beletew Abate, Tesfa Anmut Asres, Mohammed Aragaw Abera, Sentayehu Oljira Bekele, Ashenafi Kibret Sendekie, Ashenafi Kibret Sendekie

“…This study recommends making evidence-based interventions and installing functional networks among sectors to deal with common issues. …”
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Exploring perceptions of dignity among older adults living in nursing homes: a qualitative study by Kejimu Sunzi, Hui Luo, Lina Yin, Yadi Li, Xin Zhou, Cheng Lei

“…Between June and December 2023, we conducted semi-structured interviews with 35 nursing-home residents in western China (aged 65–92 years; length of stay 1 to > 7 years). …”
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Putative Mechanisms of Electroconvulsive Therapy in Treatment-Resistant Schizophrenia Examined Using Magnetic Resonance Imaging by Neelabja Roy, Dhruva Ithal, Urvakhsh Meherwan Mehta, Rakshathi Basavaraju, Rose Dawn Bharath, Nicolas R. Bolo, Jagadisha Thirthalli, Bangalore N. Gangadhar, Matcheri S. Keshavan

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Modeling prebunking strategies to contain misinformation spread by Giorgio Martalò, Marco Menale, Romina Travaglini

“…Following a classical epidemiological approach, the population is structured into interacting functional subsystems, representing individuals with different susceptibility levels. …”
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CD38‐NADase is a new major contributor to Duchenne muscular dystrophic phenotype by Antoine de Zélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de la Porte

“…Here, we identified that deletion in mdx mice of CD38, a NAD+ glycohydrolase‐producing modulators of Ca2+ signaling, led to a fully restored heart function and structure, with skeletal muscle performance improvements, associated with a reduction in inflammation and senescence markers. …”
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Investigating the eye in Down syndrome as a window to Alzheimer’s disease: the REVEAL protocol – a clinical cross-sectional study by Henrik Zetterberg, Tunde Peto, Imre Lengyel, Kathryn Saunders, Sarah Atkinson, André Strydom, Julie-Anne Little, Elaine Murray, Jamie Mitchell, Aoife Mary Louise Hunter, Lajos Csincsik

“…The REVEAL study aims to examine changes in the structure and function of the eye in individuals with DS compared with those with mild cognitive impairment (MCI) and cognitively healthy control (HC) individuals. …”
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VULVAR AND VAGINAL GRAFT VERSUS HOST DISEASE IN A PATIENT WITH CHRONIC PHASE CHRONIC MYELOID LEUKEMIA AFTER ALLOGENEIC STEM CELL TRANSPLANTATION by Esra Pirinççi, M. Orhan Ayyıldız, Abdullah Karakuş, Reyhan Gündüz

“…Incidence and severity of genital GVHD in women should be included in GVHD intervention studies.…”
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