Impact of HIV-1 capsid polymorphisms on viral infectivity and susceptibility to lenacapavir by Derek Hansen, Matthew R. Hendricks, Silvia Chang, Arthur Cai, Jason K. Perry, Thomas Aeschbacher, Ross Martin, Tomas Cihlar, Stephen R. Yant

“…Collectively, these results indicate that existing CA natural HIV-1 sequence diversity within the LEN-binding site is rare and should minimally impact LEN efficacy in treatment-naïve individuals.IMPORTANCEHIV-1 capsid protein mediates multiple essential functions throughout the viral replication cycle, making it an attractive target for therapeutic intervention. …”
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Cross-cultural insights into internet addiction and mental health: a network analysis from China and Malawi by Mengze Li, Yidi Wang, Bin Liu, Xiaoli Ni, Zhujing Ma, Fengzhan Li, Tifei Yuan, Hongyi Chen, Zhongying Wu, Qiannan Jia, Lei Song, Yinchuan Jin, Qun Yang

“…The study aimed to compare the network structures of Internet addiction and mental health symptoms among university students in China and Malawi, which provide insights into culturally sensitive prevention and intervention strategies. …”
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The impact of bariatric surgery and exercise on systemic immune inflammation index in patients with sarcopenia obesity by Cláudia Mendes, Manuel Carvalho, Jorge Bravo, Sandra Martins, Armando Raimundo

“…Higher SII is associated with lower muscle mass and function, and this may be a reflex of the compromise that obesity causes on health, in this case, increasing systemic inflammation and decreasing muscle mass and function. …”
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Inferior vena cava obstruction secondary to hepatic alveolar echinococcosis: a case report by Jingxin Yan

“…Interventional treatments significantly could improve liver function, thereby facilitating future treatment options. …”
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DEVELOPMENT AND IMPLEMENTATION OF CLUSTER POLICY: RUSSIAN AND INTERNATIONAL PRACTICE by Yu. Vertakova, V. Plotnikov, Yu. Polozhentseva

“…They differ in extent of the state intervention. The cluster policy has to be implemented taking into account specifics of spatial structure of economy of the countries and regions. …”
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The journey of playing: a qualitative evaluation of ‘Maze Out,’ a serious game for eating disorders by Maria Mercedes Guala, Helene Nygaard Nielsen, Kim Bul, David Clinton, Martina Scarpelli, Regina Christiansen, Finn Skårderud, Anette Søgaard Nielsen

“…The game functioned as a transitional object, making the experience of EDs and their challenges more comprehensible and approachable. …”
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Activity tracking devices in pregnancy: Understanding the participant experience in a longitudinal birth cohort by Ashley Redding, Dionne Coates, Andrea E. Cassidy-Bushrow, Jennifer K. Straughen, Sara Santarossa

“…Background: Improving understanding of physical activity (PA) during pregnancy can inform future interventions and support the delivery of high-quality prenatal care. …”
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A Contemporary Strategy for the Surgical Treatment of Destructive Forms of Infective Endocarditis by A. P. Medvedev, V. E. Babokin, Yu. A. Sobolev, V. V. Pichugin, V. A. Chiginev, E. N. Zemskova, N. A. Trofimov, N. L. Blagodatkina

“…Timely surgery significantly reduces the degree of heart failure and improves the NYHA functional class. In the long term, reconstructive interventions contribute to a better heart recovery than prosthetic operations. …”
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3D-printed porous tantalum for acetabular reconstruction in complex primary arthroplasty and revision of hip by Zonghan Wang, Zonghan Wang, Zonghan Wang, Ze Wang, Ze Wang, Ze Wang, Lingchuan Gu, Lingchuan Gu, Lingchuan Gu, Ying Zhang, Ying Zhang, Ying Zhang, Tiao Su, Tiao Su, Tiao Su, Jiangming Luo, Jiangming Luo, Jiangming Luo, Chengjun Huang, Chengjun Huang, Chengjun Huang, Xiaoyuan Gong, Xiaoyuan Gong, Xiaoyuan Gong, Yang Peng, Yang Peng, Yang Peng, Guangxing Chen, Guangxing Chen, Guangxing Chen

“…The porosity of the tantalum structure promoted the growth of new bone tissue into the implant, improving its stability and durability. …”
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Beyond vision loss: the impact of glaucoma on the brain by Trinita Jude Hamilton, Bettina E. Kalisch

“…Transsynaptic neural degeneration extends the RGC damage through the visual pathway and various other regions in the brain, leading to structural and functional changes. These neurodegenerative effects may result in cognitive impairment, affecting patients’ daily activities and quality of life. …”
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Diagnostic accuracy of apoptosis markers in non-alcoholic fatty liver disease in children by Yu. M. Stepanov, N. Yu. Zavhorodnia, O. Yu. Zavhorodnia, V. B. Yahmur, O. M. Tatarchuk, O. P. Petishko

“…Early diagnosis of rapidly progressive forms of NAFLD – non-alcoholic steatohepatitis (NASH) – is crucial, because therapeutic intervention in the early disease stages creates unique opportunities for the reversal of pathological changes and restoration of liver structure and function. …”
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McIndoe Vaginoplasty in MRKHS: Case Report and Literature Review by Newton Ashish Shah, Manish Yadav, Suman Verma, Digraj Yadav, Aalok Kumar Yadav, Asmita Ghimire, Hima Rijal, Poonam Koirala

“…Despite the absence of vaginal and uterine structures, individuals with MRKHS typically present with normal secondary sexual characteristics and ovarian functions. …”
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One-stage Closure of the Small Non-growing Bladder Plate: New Insight into the Anatomy of Exstrophy - Trapezoid Interpubic Ligament (TIPL) by Vasily V. Nikolaev, Nikita V. Demin

“…Conclusion: TIPL dissection enables one-stage closure in SNGBP patients who were previously considered unsuitable for this method. Early intervention supports bladder development and favorable functional outcomes. …”
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Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution by Vijit Dey, Puran C. Lailer, Tirtha K. Datta

“… Buffaloes are excellent converters of highly fibrous feeds into edible products like milk and meat due to the rumen microbiome structure and their functionality. About 37– 44% of global methane emissions, mainly due to enteric fermentation of feeds by fibrolytic bacteria and formation of methane by methanogenic archaea, present in the rumen, is contributed by ruminants and a major source of methane production in the agriculture sector. …”
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Confirming the Presence of Neurapraxia and Its Potential for Immediate Reversal by Novel Diagnostic and Therapeutic Ultrasound-Guided Hydrodissection Using 5% Dextrose in Water Wit... by Ho Won Lee, Jihyo Hwang, Chanwool Park, Minjae Lee, Yonghyun Yoon, Yeui-Seok Seo, Hyemi Yu, Rowook Park, Jaehyun Shim, Junhyuk Ann, Daniel Chiung-Jui Su, Teinny Suryadi, Keneath Dean Reeves, King Hei Stanley Lam

“…At one- and three-month follow-ups, the patient maintained complete resolution of symptoms and normal function. <b>Conclusions:</b> This case highlights two key findings: (1) HD with D5W can serve as both a diagnostic tool (confirming reversible neurapraxia through immediate response) and therapeutic intervention, and (2) early HD may circumvent prolonged disability associated with conservative management. …”
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Neural correlates of device-based sleep characteristics in adolescents by Qing Ma, Barbara J. Sahakian, Bei Zhang, Zeyu Li, Jin-Tai Yu, Fei Li, Jianfeng Feng, Wei Cheng

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Reconstruction of the Nasal Wings with the Inverted Flap Technique. Presentation of Two Cases by Raquel Rojas Bruzón, Juan Carlos Quintana Díaz, Yulexis Hechavarría Jiménez

“…This flap can have a minimum of complications if the structures are handled gently and the sutures are handled without tension. …”
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A Combined Weighting Method Based on Hybrid of Interval Evidence Fusion and Random Sampling by Ying Yan, Bin Suo

“…Cumulative probability function constructing and random sampling processes do not require any human intervention or judgment. …”
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Innovative hydrogels in cutaneous wound healing: current status and future perspectives by Prasad Sawadkar, Prasad Sawadkar, Ferdinand Lali, Ferdinand Lali, Elena Garcia-Gareta, Elena Garcia-Gareta, Elena Garcia-Gareta, Elena Garcia-Gareta, Beatriz Gil Garrido, Abdullah Chaudhry, Priya Matharu, Christos Kyriakidis, Karin Greco, Karin Greco

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Factors influencing brain recovery from stroke via possible epigenetic changes by Orjon Rroji, Carla Mucignat

“…By means of the influence of environmental (calorie restriction or physical exercise) and other factors, epigenetic instructions were found to increase levels of BDNF and enhance synaptic neurotransmission, possibly leading to larger scale changes in structural and functional assets, which may end up to cognitive and motor repair after stroke.…”
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