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1441
The spectrum of embodied intersubjective synchrony in empathy: from fully embodied to externally oriented engagement in Parkinson's disease
Published 2025-05-01“…BackgroundParkinson's disease is a prevalent neurodegenerative disorder that not only affects motor function but also impairs empathy. While the neurobiological changes underlying these deficits are known, the impact of PD on the lived experience of empathy remains poorly understood. …”
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1442
Tool Used to Assess Co-Benefits of Nature-Based Solutions in Urban Ecosystems for Human Wellbeing: Second Validation via Measurement Application
Published 2025-01-01“…In recent years, nature-based solutions have been used in urban regeneration interventions to improve the adaptation and resilience of these places, contributing to improved environmental quality and cultural ecosystem functions, including people’s physiological, social, and mental health and wellbeing. …”
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1443
Synergizing GIS and genetic algorithms to enhance road management and fund allocation with a comprehensive case study approach
Published 2025-02-01“…The research is structured around three key objectives: (1) develop a detailed GIS-based road management database incorporating inspection data and attributes of road infrastructure for proactive M&R decision-making; (2) efficiently allocate funds to maintain service delivery on deteriorated roads; and (3) pinpoint the optimal type and timing of M&R interventions to boost the condition and performance of the road segments. …”
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1444
FOXOs and their roles in acute and chronic neurological disorders
Published 2025-04-01“…Here we summarize the structure, posttranslational modifications, and translocation of FOXOs linking to their transcriptional control of cellular functions, survival, and death, emphasizing their role in regulating the cellular response to some acute insults and chronic neurological disorders. …”
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1445
Regulation of intestinal flora by Suaeda salsa extract ameliorates hyperglycemia in a mouse model of type 2 diabetes mellitus
Published 2024-12-01“…Taken together, these findings demonstrate that SSE can alleviate T2DM and its complications by improving glycemia-related indicators and modulating the structure of intestinal flora.…”
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1446
Correlation between mitral annular plane systolic excursion (MAPSE) at different degrees of ejection fraction in patients with diabetes mellitus
Published 2024-09-01“…Diabetic cardiomyopathy is characterized by myocardial structure and function abnormality in the absence of other cardiovascular risk factors. …”
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1447
Role of community health workers in type 2 diabetes mellitus self-management: A scoping review.
Published 2018-01-01“…Models of CHW care included facility linked nurse-led CHW coordination, facility-linked CHW led coordination and standalone CHW interventions without facility interaction.<h4>Conclusion</h4>CHWs play several roles in T2DM self-management, including structured education, ongoing support and health system advocacy. …”
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1448
Assessment of right ventricular endocardial fibroelastosis in fetuses with critical pulmonary stenosis and pulmonary atresia with intact ventricular septum
Published 2025-01-01“…Among the ten patients who underwent fetal cardiac intervention (FCI), the restoration of the TV z-score was more significant in Grade 2 RV EFE fetuses than in Grade 1 EFE fetuses. …”
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1449
Muscle-to-action mapping for intuitive training of muscle synergies in post-stroke upper-limb rehabilitation
Published 2025-04-01“…Functional improvements were reflected in the Fugl-Meyer Assessment for the Upper Extremity and Wolf Motor Function Test scores, which increased by 3.36 and 6.45 points, respectively. …”
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1450
P88 | REGENERATIVE MEDICINE, REHABILITATION AND CYTO-HISTOCHEMISTRY: RECENT EVALUATIONS OF INTEGRATED TREATMENTS
Published 2025-08-01“…In the field of tissue engineering cyto-histochemistry plays a crucial role in tissue engineering, allowing researchers to analyze tissue structure and cell behavior. This knowledge can be used to develop more effective tissue engineering strategies. …”
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1451
Bioinformatics analysis of JUP in patients with acute myocardial infarction and its potential application in clinical prognostic evaluation
Published 2025-05-01“…BackgroundJunctional Plakoglobin (JUP) is a critical protein involved in intercellular junctions, playing a significant role in maintaining the structure and function of myocardial cells. However, the expression of JUP in acute myocardial infarction (AMI) and its potential applications in prognostic evaluation of patients remain underexplored. …”
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1452
“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station
Published 2025-04-01“…At the settlement scale, the Mask Region-based Convolutional Neural Network (Mask R-CNN) deep learning model is utilized to identify architectural spatial features, categorizing three typical building types: traditional pitched-roof buildings, uniformly planned flat-roof buildings, and color steel plate-modified structures. Through multi-source data fusion (including remote sensing, demographic statistics, and compensation records) and field investigations, the research quantitatively analyzes the “locality – adaptation” reconstruction process of resettlement communities across the three spatial dimensions of living, production, and cultural spaces.Results1) Land cover evolution: Water storage of hydropower station inundates 37.12 km2 of land (including 21.61 km² of high-quality cultivated land), resulting in a loss of 43.68% of settlement production space. 2) Adjustment of architectural space: 65.8% of dwellings in the original villages are traditional timber-earth buildings with a tile roof, which adapt to the climate environment of concentrated rainfall and sufficient sunshine in the Jinsha River Basin. 48.7% of the resettlement sites adopt unified flat roof planning, and 51.3% realize functional optimization through self-construction or renovation, with the average renovation area reaching 230.9 m2. 3) Transformation of livelihood system: The annual compensation mechanism only restores 15.79% of the cultivated land allocation before resettlement, and the proportion of compensation income drops from 82.71% in the initial stage of relocation to 33.15% after long-term resettlement, driving the adjustment of crop structure to high value-added cash crops. 4) Cultural space reconstruction: In the context of the disappearance of traditional water transport functions, the three cultural relics reconstructed in different places show a symbolic turn. …”
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1453
Temporal network analysis of gut microbiota unveils aging trajectories associated with colon cancer
Published 2025-05-01“…Extensive metagenomic sequencing of fecal samples allowed for the exploration of both the structural and functional profiles of the microbiome, with findings validated in an independent cohort to ensure robustness. …”
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1454
The Ubiquitin-Proteasome Pathway in Huntington's Disease
Published 2008-01-01“…Accompanying neuronal death, mutant huntingtin aggregates in large macromolecular structures called inclusion bodies. The function of the machinery for intracellular protein degradation is linked to huntingtin toxicity and components of this machinery colocalize with inclusion bodies. …”
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1455
Brain Morphology in Mass Murderers: An In-Depth Exploration
Published 2025-06-01“…This review examines the brain morphology of mass murderers, focusing on structural and functional abnormalities in brain regions involved in aggression, decision-making, and emotional regulation. …”
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1456
Investigating the Concept of Authenticity in Restoration in Light of Archive Documents: Kayseri Sahabiye Madrasah
Published 2024-08-01“…Information gaps in the structure’s conservation history are explained by using the relevant documents, and the approach to authenticity in conservation during the period of conservation intervention is questioned by considering the effective authorities, actors, and theoretical, technical, legal, and administrative functioning in practice. …”
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1457
AF6 regulates intestinal IgA via crosstalk between intestinal epithelial cells and immune cells in inflammatory bowel disease
Published 2025-07-01“…Some polar proteins have been reported to perform functions other than maintaining cell structure. In this study, we reported that the polar protein AF6 expressed by intestinal epithelial cells (IEC) can regulate the expression of MHCII in epithelial cells, thus affecting the cross dialogue between IECs and immune cells, and promoting the secretion of IgA by B cells to play a protective function. …”
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1458
463 Identification of molecular and cellular events during recurrence of focal segmental glomerulosclerosis in human allografts
Published 2025-04-01“…Objectives/Goals: The identification of the cascade of molecular and cellular events occurring during the progression of focal segmental glomerulosclerosis in human kidney biopsies from kidney transplant (KTx) recipients (KTR) with normal function or recurrent FSGS to determine potential targets of intervention and therapy. …”
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1459
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration
Published 2025-04-01“…BSHXF restored TGF-β/Smad pathway activity by downregulating miR-199a-3p expression, thereby improving disc structure and function. This integrated approach offers a novel multi-target intervention strategy for IDD, demonstrating significant therapeutic potential.…”
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1460
A Systems Approach to Monitoring Antimicrobial Consumption and Use in Uganda
Published 2025-03-01“…Methods: Uganda's approach recognizes that AMUC is influenced by healthcare delivery, governance structures, financing mechanisms, workforce capacity, and information systems. …”
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