Innovative gene delivery systems for retinal disease therapy by Hongguang Wu, Ling Dong, Shibo Jin, Yongwang Zhao, Lili Zhu

“…The human retina, a complex and highly specialized structure, includes multiple cell types that work synergistically to generate and transmit visual signals. …”
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Complex associations between anxiety, depression, and resilience in a college student sample: a network analysis by Hui Wang, Min Wang, Xiuchao Wang, Tingwei Feng, Xufeng Liu, Wei Xiao

“…Bridge centrality indices of variables within the network were computed, with particular emphasis on the significance of bridge symptoms within the network structure.ResultsSignificant covariation was observed between anxiety and depression symptoms. …”
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Effects of customized orthoses on foot morphology and pressure in patients with accessory navicular syndrome by Xiaopeng Pu, Wenwen Xing, Zishen Cheng, Yantao Wang, Yuqing Wang, Yaxing Zhang, Liangliang Jiang, Bin Liu, Qiangjun Kang

“…Split into two groups: custom orthotics (intervention) or regular insoles (control). Evaluated at 3, 6, 12 months on foot structure (arch, navicular, etc.) and function (pressure, force-time integral, VAS pain). …”
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Baseline gut microbiome and metabolites are correlated with changes in alcohol consumption in participants in a randomized Zonisamide clinical trial by Liv R. Dedon, Hanshu Yuan, Jinhua Chi, Haiwei Gu, Albert J. Arias, Jonathan M. Covault, Yanjiao Zhou

“…Overall microbiome community structure at baseline differed between high and low reducers of alcohol drinking (67–100% and 0–33% drinking reduction, respectively; p = 0.034). …”
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The impact of adolescent physical activity on quality of life: a moderated mediation model by Sen Ma, Yan Gao, Liangyu Zhao, Wenze Sui, Yuke Yang, Yining Hu

“…BackgroundQuality of Life (QoL) is a crucial multi-dimensional structure in the development process of adolescents. …”
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Identification and analysis of driving factors for ecosystem service bundles in Shanxi Province under multiple scenario simulations by Guofeng Dang, Guibin Li, Jinzhou Hu

“…Abstract In the context of carbon peak and energy structure transformation, ecosystem service bundle(ESB) have obvious changes. …”
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Low Molecular Weight Fucoidan Alleviates Cardiac Dysfunction in Diabetic Goto-Kakizaki Rats by Reducing Oxidative Stress and Cardiomyocyte Apoptosis by Xinfeng Yu, Quanbin Zhang, Wentong Cui, Zheng Zeng, Wenzhe Yang, Chao Zhang, Hongwei Zhao, Weidong Gao, Xiaomin Wang, Dali Luo

“…Ventricle staining with H-E or Sirius Red was performed to investigate the structural changes in myocardium. Functional evaluation demonstrated that LMWF has a beneficial effect on DCM by enhancing myocardial contractility and mitigating cardiac fibrosis. …”
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Volumetric 3D Reconstruction of Large Osteochondral Lesions of the Talus Being Reconstructed with Viable Osteochondral Allograft Combined with Autograft by Nathaniel Zona BA, Daniel Moon MD, MS, MBA

“…A stable bony base and viable cartilage rim was established, removing all damaged cartilage and nonstructural bone debris from the OLT. Talar body structure and morphology was restored using autograft iliac crest or tibial placed into the bony defect. …”
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Specific cognitive deficits in preschool age correlated with qualitative and quantitative MRI parameters in prematurely born children by Mirna Kostović Srzentić, Marina Raguž, David Ozretić

“…The relationship between structural changes on at term magnetic resonance imaging (MRI) and cognitive deficits in the preschool age should be a special focus due to timely intervention. …”
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Does model type influence the effectiveness of combined action observation and motor imagery training for novices learning an Ankle Pick takedown? by Samantha Chye, Ashika Chembila Valappil, Ryan Knight, Andrew Greene, David Shearer, Cornelia Frank, Ceri Diss, Adam Bruton, Adam Bruton

“…Both the AOMIOTHER and Control conditions led to improved functional changes in mental representation structures while the structures for the AOMISELF condition became less similar to the reference structure over time.DiscussionCollectively, the largely null findings (n = 13, 92.86%) suggest that physical practice has the strongest influence on motor adaptations for this complex motor skill at these early stages of learning. …”
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Genetically engineered MSC-derived hybrid cellular vesicles for ROS-scavenging and mitochondrial homeostasis in hepatic ischemia-reperfusion injury by Pu Shen, Kaijun Huang, Xuanlin Zhang, Guiyuan Yin, Meiting Qin, Hua Ma, Zhijin Fan, Yuhui Liao

“…This therapeutic cascade facilitated mitochondrial structural and functional restoration via multiple pathways: Resveratrol specifically activated PINK1-mediated mitophagy, as confirmed by increased LC3 and beclin-1 expression, thereby promoting selective clearance of depolarized mitochondria. …”
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The role of vascularity and the fibrovascular interface in interstitial lung diseases by Jana Dietrich, Alice Kang, Birger Tielemans, Stijn E. Verleden, Hassan Khalil, Florian Länger, Philipp Bruners, Steven J. Mentzer, Tobias Welte, Michael Dreher, Danny D. Jonigk, Maximilian Ackermann

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Right ventricular outflow tract morphology and its clinical significance for invasive procedures by Marcin Jakiel, Rafał Jakiel, Jakub Batko, Edyta Dyngosz, Maria Kurek, Karolina Gutkowska, Jakub Hołda, Filip Bolechała, Marcin Strona, Mateusz K. Hołda

“…In conclusion, this study provides a detailed definition, along with anatomical and structural analysis of the RVOT, highlighting its complex morphology and its significant role in cardiac functionality and clinical interventions.…”
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The relationship between eHealth literacy and oral frailty among older adults: the serial mediating effects of self-efficacy and oral health by Jie Wu, Xin-xin Wang, Min Xu, Kang-ping Liu, Li-ling Xu, Ying Zhang

“…Abstract Background Oral frailty can cause many adverse consequences, including by impairing basic oral functions such as chewing and speaking; furthermore, it is closely related to overall systemic health. …”
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Sodium alginate microspheres loaded with Quercetin/Mg nanoparticles as novel drug delivery systems for osteoarthritis therapy by Jun Chen, Guoya Wu, Jian Wu, Zhijian Jiao

“…Given the benefits of both quercetin (Que) and Magnesium ion (Mg2+) in OA treatment, coupled with the structural properties of Que, we have innovatively developed the Que-Mg2+ nanoparticles (NPs), aiming to deliver both Que and Mg2+ simultaneously and achieve enhanced therapeutic outcomes for OA. …”
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Sleep duration, sleep disturbances and skeletal muscle mass change over time: A population-based longitudinal analysis in Peru [version 3; peer review: 1 approved, 2 approved with... by Enrique S. Nuñez-del-Arco, Renzo A. Agurto-García, Rodrigo M. Carrillo-Larco, J. Jaime Miranda, Antonio Bernabe-Ortiz

“…Background The skeletal muscle has mainly a structural function and plays a role in human’s metabolism. …”
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Gradual Variation-Based Dual-Stream Deep Learning for Spatial Feature Enhancement With Dimensionality Reduction in Early Alzheimer’s Disease Detection by Najmul Hassan, Abu Saleh Musa Miah, Taro Suzuki, Jungpil Shin

“…Alzheimer’s disease (AD) is one of the most common neurological brain disorders, developing gradually and primarily causing the deterioration of brain function, leading to memory loss and behavioral changes. …”
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Modulatory Role of Hesperetin–Copper(II) on Gut Microbiota in Type 2 Diabetes Mellitus Mice by Xi Peng, Yushi Wei, Deming Gong, Guowen Zhang

“…Flavonoid–metal complexes have become one of the research hotspots in the field of health foods due to their unique structural and functional properties. Methods: In this study, the effect of hesperetin–copper(II) complex [Hsp–Cu(II)] on the gut microbiota of mice with T2DM was investigated by the 16S rRNA high-throughput sequencing. …”
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Problem of consciousness in learning systems and environments by S. F. Sergeev, A. S. Sergeeva

“…These worlds have different significance for the subject, defining the nature of its activities.We analyzed models the structure of reality and reality as a world’s refl ection offered by Karl Popper, K. …”
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The role of ferroptosis-related non-coding RNA in liver fibrosis by Guozhu Zhang, Kejia Wu, Kejia Wu, Xiaobo Jiang, Yuan Gao, Dong Ding, Hao Wang, Chongyuan Yu, Xiaozhong Wang, Naixin Jia, Li Zhu

“…This pathological progression is characterized by the excessive accumulation of the extracellular matrix (ECM), which leads to significant structural disruption and ultimately impairs liver function. …”
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