Upper and Lower Limb Motor Function Correlates with Ipsilesional Corticospinal Tract and Red Nucleus Structural Integrity in Chronic Stroke: A Cross-Sectional, ROI-Based MRI Study by Denise M. Peters, Julius Fridriksson, Jessica D. Richardson, Jill C. Stewart, Chris Rorden, Leonardo Bonilha, Addie Middleton, Stacy L. Fritz

“…To investigate the neural basis of upper/lower limb motor deficits poststroke by correlating measures of motor function with diffusion tensor imaging-derived indices of white matter integrity (fractional anisotropy (FA), mean diffusivity (MD)) in primary and secondary motor tracts/structures. …”
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Efficient structure learning of gene regulatory networks with Bayesian active learning by Dániel Sándor, Péter Antal

“…Abstract Background Gene regulatory network modeling is a complex structure learning problem that involves both observational data analysis and experimental interventions. …”
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Stability Analysis of SEIAR Model with Age Structure Under Media Effect by Hongliang Gao, Fanli Zhang, Jiemei Li

“…In this paper, we establish an age-structured SEIAR epidemic model that incorporates media effects and employ the exponential function approach to demonstrate the crucial role of media influence in disease prevention and control. …”
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Diverse actions of 15 structurally unrelated mitochondrial uncouplers in cells and mice by Divya P. Shah, Calum S. Vancuylenburg, Ellen M. Olzomer, Sing-Young Chen, Robert J. Grams, Martina Beretta, Frances L. Byrne, Webster L. Santos, Kyle L. Hoehn

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An Approach to, and Tool for, Predicting the Time Course of an Infectious Disease Outbreak as a Function of Behavioral Interventions by Abebe HT, Siraj A, Berhane K, Siraj D, Van Breukelen GJ

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Cognitive training gain transfer in cognitively healthy aging: per protocol results of the German AgeGain study by Florian U. Fischer, Florian U. Fischer, Bianca Kollmann, Bianca Kollmann, Dominik Wolf, Alexandra Sebastian, Alexandra Sebastian, Kristel Knaepen, David Riedel, Andreas Mierau, Andreas Mierau, Nicolas Ruffini, Nicolas Ruffini, Kristina Endres, Kristina Endres, Jennifer Winter, Heiko K. Strüder, Gerard N. Bischof, Gerard N. Bischof, Sofia Faraza, Sofia Faraza, Bernhard Baier, Harald Binder, Alexander Drzezga, Alexander Drzezga, Alexander Drzezga, Stefan Teipel, Stefan Teipel, Andreas Fellgiebel, Andreas Fellgiebel, Oliver Tüscher, Oliver Tüscher, Oliver Tüscher, Oliver Tüscher, Oliver Tüscher

“…Cognitive training interventions aim to attenuate cognitive decline, but training gains need to be transferable to untrained cognitive abilities to influence everyday function. …”
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Machine-learning models for Alzheimer’s disease diagnosis using neuroimaging data: survey, reproducibility, and generalizability evaluation by Maryam Akhavan Aghdam, Serdar Bozdag, Fahad Saeed, Alzheimer’s Disease Neuroimaging Initiative

“…To better understand the landscape, we surveyed the major preprocessing, data management, traditional machine-learning (ML), and deep learning (DL) techniques used for diagnosing AD using neuroimaging data such as structural magnetic resonance imaging (sMRI), functional magnetic resonance imaging (fMRI), and positron emission tomography (PET). …”
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The Effects of Exercise Intervention in Older Adults With and Without Sarcopenia: A Systematic Review by Jeremy Cabrolier-Molina, Alexandra Martín-Rodríguez, Vicente Javier Clemente-Suárez

“…This systematic review, conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD42024619693), aimed to evaluate the effects of physical exercise interventions on muscle function and fall risk in older adults with and without sarcopenia. …”
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FUNCTIONAL STATUS OF HEART AND KIDNEYS AND CARDIO-RENAL INTERACTIONS IN PATIENTS AFTER CORONARY REVASCULARISATION INTERVENTION by M. E. Statsenko, D. V. Bolotov

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Adaptation and validation of the Washington group/unicef child functioning module in a nationally representative sample of Canadian children and youth by Emma Nolan, Katherine Cost, Ryan Miller, Li Wang, Chen Yun-Ju, Jordan Edwards, Eric Duku, Stelios Georgiades, Peter Szatmari, Harriet MacMillian, Charlotte Waddell, Katholiki Georgiades

“…This study focuses on the cognitive, emotional, and behavioral components of the WG/UNICEF CFM, as these domains are particularly relevant to understanding child and youth mental health and developmental functioning. The objective of this study was to examine the latent structure of these domains using a graded response scale in a nationally representative sample of Canadian children and youth aged 5–17 years and to evaluate how this approach captures the dimensional nature of functional difficulties. …”
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Structural Defects Associated with Craniectomy Induce Neuroinflammation and Blood–Brain Barrier Permeability by Aria W. Tarudji, Brandon Z. McDonald, Evan Curtis, Connor Gee, Forrest M. Kievit

“…While craniectomies are commonly used in TBI research, inadvertent dura disruption can result in structural deficits, impacting cellular function and neurobehavioral outcomes. …”
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Optimal exercise interventions for enhancing cognitive function in older adults: a network meta-analysis by Han Han, Jinhao Zhang, Fan Zhang, Fanghui Li, Zhijian Wu

“…These findings support the integration of structured exercise interventions into aging and dementia prevention strategies, with particular attention to optimal protocol design and population targeting.…”
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Structural Characterization and Bioactivity Evaluation of Selenium-Modified Dihydromyricetin from Vine Tea by Kaixuan Cheng, Guangqian Hou, Shengqi Mei, Xingxing Gao, Chi Zhang, Longchen Shang, Shuai Chen

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Machine Learning-Driven GLCM Analysis of Structural MRI for Alzheimer’s Disease Diagnosis by Maria João Oliveira, Pedro Ribeiro, Pedro Miguel Rodrigues

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Novel FGF21 analogues through structure-based optimization for therapeutic development by Guo Yiqing, Bao Yuxuan, Chen Zhichao, Rao Zhiheng, Luo Yongde, Ye Sheng, Liu Si

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Neural, cognitive and psychopathological signatures of a prosocial or delinquent peer environment during early adolescence by Yu Liu, Songjun Peng, Xinran Wu, Zhaowen Liu, Zhengxu Lian, Huaxin Fan, Nanyu Kuang, Xinrui Gu, Senyou Yang, Yechen Hu, Xi Jiang, Yufeng Zhang, Wei Cheng, Jianfeng Feng, Barbara J. Sahakian, Xingming Zhao, Trevor W. Robbins, Benjamin Becker, Jie Zhang

“…Here, we capitalized on data from 7806 adolescents (age = 12.02 ± 0.67) from the Adolescent Brain Cognitive Development (ABCD) study, to determine associations between two distinct peer environments (proportion of prosocial or delinquent friends) and the structural and functional architecture of the brain, cognition, as well as behavioral and emotional dysregulation. …”
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The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases by Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida

“…Therefore, it is important to analyze the complex functions of DCs within TLS in order to enhance our fundamental understanding of immune regulation but also as a possible route to create innovative clinical interventions designed for the specific needs of patients with diverse pathological diseases.…”
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Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period by V. V. Lazarev, K. R. Ermolaeva, V. S. Kochkin, L. E. Tsypin, T. G. Popova, D. V. Nikolaev, A. A. Bologov, N. N. Vaganov

“…Results. 1.5% Reamberin solution was found to contribute to earlier and significant improvement in the function of cellular structures in children in the perioperative period.…”
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Structure-based mechanism of RyR channel operation by calcium and magnesium ions. by Alexandra Zahradníková, Jana Pavelková, Miroslav Sabo, Sefer Baday, Ivan Zahradník

“…The proposed mechanism of RyR operation provides a new interpretation of the structural and functional data of mammalian RyR channels on common grounds. …”
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Structure and oxygen saturation recovery of sparse photoacoustic microscopy images by deep learning by Shuyan Zhang, Jingtan Li, Lin Shen, Zhonghao Zhao, Minjun Lee, Kun Qian, Naidi Sun, Bin Hu

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