Brain Connectivity Yields Insights into the Pathogenesis of Epilepsy and Subtypes: Evidence from Mendelian Randomization Analysis by Zhipeng He, Shishi Tang, Yurong Hu, Yuxuan Li, Junhao Liang, Li Fang, Miaoxin Li, Ziyi Chen, Yi Zhou

“…This insight could yield crucial intervention strategies to different subtypes of epilepsy at the level of brain structure and functional networks.…”
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A comprehensive assessment of health indicators among tribal populations in Odisha, India (Odisha Tribal Family Health Survey): a community-based, cross-sectional studyResearch in... by Jaya Singh Kshatri, Kavitha AK, Tanveer Rehman, Haimanti Bhattacharya, Dinesh Bhuyan, Asit Mansingh, Uttam Kumar Sahoo, Moushumi Nayak, Swagatika Kanungo, Debdutta Bhattacharya, Sanghamitra Pati

“…Data collection involved the use of structured tools at the household and individual levels, anthropometric measurements, point-of-care tests (including blood pressure, random blood glucose, and haemoglobin levels, as well as haemoglobinopathy screening), and laboratory analyses of blood serum samples (for liver function, kidney function, and lipid and iron profiles). …”
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Neurobiological and Microbiota Alterations After Bariatric Surgery: Implications for Hunger, Appetite, Taste, and Long-Term Metabolic Health by Sebastián Chapela, Ludwig Alvarez-Córdova, Andres Martinuzzi, Rosario Suarez, Victoria Gonzalez, Ezequiel Manrique, Janeth Castaño, Gianluca Rossetti, Luigi Cobellis, Vincenzo Pilone, Evelyn Frias-Toral, Luigi Schiavo

“…Neuroimaging studies reveal structural and functional changes in brain regions involved in reward processing and cognitive control, contributing to reduced cravings and altered food choices. …”
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Parasitic worms: knowledge, attitudes, and practices in Western Côte d'Ivoire with implications for integrated control. by Cinthia A Acka, Giovanna Raso, Eliézer K N'goran, Andres B Tschannen, Isaac I Bogoch, Essane Séraphin, Marcel Tanner, Brigit Obrist, Jürg Utzinger

“…<h4>Principal findings</h4>Access to clean water was lacking in both communities and only a quarter of the households had functioning latrines. There was a better understanding of soil-transmitted helminthiasis than intestinal schistosomiasis, but community-based rather than school-based interventions appeared to improve knowledge of schistosomiasis. …”
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Effect of Raspberry (<i>Rubus indeaus</i> L.) Juice Fermented by <i>Limosilactobacillus fermentum</i> FUA033 on the Human Gut Microbiota Cultured In Vitro: A Multi-Omics Approach by Ziyan Hua, Yunfan Lv, Han Zhang, Tianyi Mao, Ruyu Xv, Mingxuan Pan, Yadong Hu, Shu Liu, Yaowei Fang

“…The modulation of the gut microbiota through dietary interventions has emerged as a promising approach, leading to significant interest in the development of functional foods that provide health benefits. …”
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Gaining insights into pet owner understanding/lived experience of canine chronic kidney disease using survey and social media data by Georgina Tarrant, Luke Boyden, Luke Boyden, Taranpreet Rai, Taranpreet Rai, Andrea Wright, Alasdair J. C. Cook, Kevin Wells, Kevin Wells

“…IntroductionChronic kidney disease (CKD) is a common and progressive condition in dogs characterized by irreversible damage to one or both kidneys over an extended period leading to gradual decline in kidney function. Early diagnosis is crucial to improve quality of life and increase survival through medical interventions.MethodsThis study investigated pet owner understanding of this condition using insights gained by comparing pet owner survey responses with bulk harvested social media discussions on canine CKD. …”
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Factors associated with participation in a proton therapy clinical trial: a cross-sectional survey of Danish patients with head and neck cancer by Anne Wilhøft Kristensen, Kenneth Jensen, Annesofie L. Jensen, Susanne O. Dalton, Jesper Eriksen, Jeppe Friborg, Cai Grau

“…Background and purpose: Participation in proton therapy (PT) trials may be affected by structural, clinical, and individual factors, potentially excluding certain patient groups. …”
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Exercise, memory, and the hippocampus: Uncovering modifiable lifestyle reserve factors in refractory epilepsy by Alena Stasenko, Erik Kaestner, Adam Schadler, Evan Brady, Jonathan Rodriguez, Rebecca W. Roth, Ezequiel Gleichgerrcht, Jonathan L. Helm, Daniel L. Drane, Carrie R. McDonald

“…Due to the beneficial impact of exercise on hippocampal health and the vulnerability of the hippocampus in medication-resistant temporal lobe epilepsy (TLE), exercise could present a promising intervention in TLE. We investigated whether exercise engagement is associated with verbal memory function and hippocampal integrity in 29 young to middle-aged adults with refractory TLE and 21 demographically matched controls. …”
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The relationship between symptoms of gender dysphoria and social anxiety in transgender young adults: a network analysis by Jiaqi Li, Yi Feng, Wenbang Niu, Shicun Xu, Yajun Bu, Yuanyuan Wang

“…In transgender women’s network structure, “Distressing bodily functions” was positively connected to “Hard time working,” while it was positively linked to “Nervous speaking” in that of the non-binary group. …”
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Multimodality Imaging in Aldosterone-Induced Cardiomyopathy: Early Detection and Prognostic Implications by Francesca Zoccatelli, Gabriele Costa, Matteo Merlo, Francesca Pizzolo, Simonetta Friso, Luigi Marzano

“…Multimodality cardiac imaging, led primarily by conventional and speckle-tracking echocardiography, and complemented by exploratory cardiac magnetic resonance (CMR) techniques such as T1 mapping and late gadolinium enhancement, enables non-invasive assessment of structural, functional, and tissue-level changes in aldosterone-mediated myocardial damage. …”
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Dysregulated ac4C modification of mRNA in a mouse model of early-stage Alzheimer’s disease by Hao-Nan Ji, Hai-Qian Zhou, Jing-Bo Qie, Wen-Mei Lu, Hai-Tao Gao, Dan-Hong Wu

“…Strikingly, acRIP-seq revealed notable variations in ac4C modification on mRNAs, particularly those associated with synaptic structure and function, in the hippocampus of 3-months-old 5×FAD mice, compared with WT littermates. …”
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Molecular architectures of glycosylated dendronized bottle brushes in action: Biocompatibility and anti-amyloidogenic activity of pseudo-glycodendrimers by Tom Kösterke, Radika Thakore, Silvia Moreno, Jan Skov Pedersen, Brigitte Voit, Oxana Klementieva, Dietmar Appelhans

“…Importantly, it is demonstrated that PGDs can be multi-functionalized by various sugar molecules, dyes, and/or peptides in a final one-pot approach. …”
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Tracheobronchial ossification in children: a case report and review of the literature by Yan Ruan, Shan Chen, Ling Zhang, Huiyun Huang, Weiwei Tang, Lizhi Li

“…Imaging revealed airway wall nodules and structural lung changes. Bronchoscopy showed scattered white nodules; histopathology confirmed mucosal ossification with focal bone marrow formation. …”
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Inflammaging as the basis of age-associated diseases by O. V. Artemyeva, L. V. Gankovskaya

“…Immunosenescence is understood as structural and functional changes in both adaptive and innate immunity systems. …”
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Mitochondrial genomic alterations in cholangiocarcinoma cell lines. by Athitaya Faipan, Sirinya Sitthirak, Arporn Wangwiwatsin, Nisana Namwat, Poramate Klanrit, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Natcha Khuntikeo, Luke Boulter, Hasaya Dokduang, Watcharin Loilome

“…Our results underscore the diverse mtDNA mutation landscape in CCA cell lines, highlighting the potential impact of these mutations on mitochondrial function and CCA cell line progression. Future research is required to investigate the functional impacts of these variants, their interactions with nuclear DNA in CCA, and their potential as targets for therapeutic intervention.…”
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Lowering Blood Lipids and Regulating Intestinal Flora Effects of Blueberry Enzyme in Hyperlipidemic Mice by Ya DANG, Yuyu QIAO, Gege LEI, Binyan YANG

“…After 4 weeks of drug intervention, the mice's weight, serum lipid levels, organ changes and the liver function of each group mice were measured, and the pathological sections of liver, kidney and colon were also monitored. …”
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A COSMIN systematic review of instruments for evaluating health-related quality of life in people with Hereditary Angioedema by Irene Baroni, Giulia Paglione, Giada De Angeli, Miriam Angolani, Edward Callus, Arianna Magon, Gianluca Conte, Stefano Terzoni, Maura Lusignani, Rosario Caruso, Andrea Zanichelli

“…HAE often compromises the HRQoL due to the impact on functional capacity caused by edema, pain, other symptoms, and psychosocial factors. …”
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CSEPC: a deep learning framework for classifying small-sample multimodal medical image data in Alzheimer’s disease by Jingyuan Liu, Xiaojie Yu, Hidenao Fukuyama, Toshiya Murai, Jinglong Wu, Qi Li, Zhilin Zhang

“…The architecture first extracts balanced multiscale features from structural MRI (sMRI) data and functional MRI (fMRI) data using a cross-scale pyramid module. …”
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Patterns and Associated Factors of Congenital Anomalies Among Neonates in 14 Yemeni Governorates 2021–2023: A Case: Control Study by Hiam Al-Atnah, Anas Al-Qubati, Amir Addin Al-Hashedi, Muath Al-Saidy, Saleh Al-Shawish, Moamer M. Badi, Najeeb Al-Qubati, Yasser Ghaleb, Maha Al-Muntaser

“…Background: Long-term disability and a reduced quality of life are often associated with congenital anomalies (CAs), which present as structural, functional, or metabolic defects. This study provides a comprehensive view of neonatal congenital anomalies in 14 Yemeni governorates, a significant but often overlooked public health concern. …”
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Development and psychometric evaluation of the 12-item Polish version of the Pain Vigilance and Awareness Questionnaire by Joanna Kłosowska, Aleksandra Budzisz, Daryna Rubanets, Izabela Anna Łaska, Helena Bieniek, Justyna Brączyk, Karolina Wiercioch-Kuzianik, Elżbieta Anita Bajcar, Magdalena Żegleń, Magdalena Niedbał, Julia Badzińska, Anna Przeklasa-Muszyńska, Lance M. McCracken, Przemysław Bąbel

“…Study 2 involved 148 hospital-recruited chronic pain patients who completed the adapted scale and measures of pain intensity and functional limitations. None of the previously proposed models describing the factor structure of the PVAQ scale adequately fit the data. …”
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