ID071 Early stimulation strategies for children aged 0 to 3 years old with cerebral palsy: overview of systematic reviews by Aurélio Matos Andrade, Juliana da Motta Girardi, Rhaila Cortes Barbosa, Valdenize Tiziani, Flavia Tavares Silva Elias, Indyara de Araujo Morais, Priscilla Lemos Gomes

“…The interventions resulted in significant improvements in child development, body functions and structures, and functional abilities of activities and participation, such as locomotor movements, gait pattern, postural control, balance, muscle tone, joint mobility, visual and auditory functions, fine and gross motor skills, execution of activities of daily living, self-initiated movements, self-care, visual perception, interaction, face-to-face contact, vocalization and communication. …”
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Evaluation of SCORED as a diagnostic tool for early detection of chronic kidney disease (CKD) and End-stage renal disease (ESRD): A hospital-based study by Osama F Mosa

“… Background: Chronic Kidney Disease (CKD) and End-Stage Renal Disease (ESRD) are significant public health problems characterized by structural or functional anomalies of the kidneys. CKD is considered one of the ma-jor non-communicable diseases and its prevalence is increasing rapidly in Saudi Arabia. …”
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Segmentation of focal liver lesions and virtual resection based on computed tomography data by P. M. Zelter, A. V. Kolsanov, Yu. S. Pyshkina

“…The obtained results indicate that the use of the ‘Autoplan’ system plugins for planning an abdominal surgery allows doctors: 1) to carry out the segmentation of liver, focal lesions and blood vessels; 2) to determine the location of a focal formation in a particular segment, their combination; 3) to perform a virtual resection, evaluate the structures passing through it; 4) to choose the optimal tactics of intervention or  abandon it due to objective anatomical reasons.…”
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Insight into the effects of Omega-3 fatty acids on gut microbiota: impact of a balanced tissue Omega-6/Omega-3 ratio by Bo Zou, Dan Zhao, Shuang Zhou, Jing X. Kang, Jing X. Kang, Bin Wang, Bin Wang

“…Emerging evidence suggests that Omega-3 polyunsaturated fatty acids (PUFAs) are essential structural and functional nutrients that significantly influence the composition and function of the gut microbiota, a key mediator of host health. …”
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Determinant Factors of Stress in Caregivers of Patients With Schizophrenia: Cross-Sectional Study by Isymiarni Syarif, Hasnawati Amqam, Saidah Syamsuddin, Veni Hadju, Syamsiar Russeng, Yusran Amir

“…Strengthening these dimensions is essential to mitigating the psychological toll of caregiving and sustaining caregivers’ functional well-being. Evidence increasingly supports that empowering caregivers through structured support systems and educational initiatives can substantially alleviate stress-related burdens and improve care continuity for individuals with schizophrenia.…”
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Butylated hydroxytoluene (BHT) induces zebrafish spinal cord defects and scoliosis by inhibiting the hedgehog pathway by Hao Cheng, Yulian Li, Fasheng Liu, Shanshan Zhu, Li Chen, Huiqiang Lu, Xiaowen Shi, Ling Huang

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Evaluation of in situ tissue-engineered arteriovenous grafts suitable for cannulation in a large animal model by Paul J. Besseling, Wojciech Szymczyk, Martin Teraa, Raechel J. Toorop, Paul. A. A. Bartels, Boris Arts, Rob C. H. Driessen, Arturo M. Lichauco, Hidde C. Bakker, Joost O. Fledderus, Gert J. de Borst, Patricia Y. W. Dankers, Carlijn V. C. Bouten, Marianne C. Verhaar

“…Abstract The sustainability of vascular access for hemodialysis is limited by frequent interventions and the inability of synthetic grafts to self-heal. …”
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Diagnosis and Management of Giant Hepatic Hemangioma: The Usefulness of Contrast-Enhanced Ultrasonography by Masaki Maruyama, Osamu Isokawa, Koki Hoshiyama, Ayako Hoshiyama, Mari Hoshiyama, Yoshihiro Hoshiyama

“…The major advantage is the real-time observation of the vascular structure and function of the Kupffer cells. By this procedure, we can carefully follow the tumor growth or character change in a hemangioma and decide the timing of therapeutic intervention, since abdominal pain, abdominal mass, consumptive coagulopathy, and hemangioma growth are the signs for the therapeutic intervention. …”
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Human Pluripotent Stem Cell‐Derived Skeletal Muscle Organoid Model of Aging‐Induced Sarcopenia by Seongjun Park, Min‐Kyoung Shin, Dong Seok Jeong, Xin Yi Yeo, Yeo Jin Kim, Junaid Muhammad, Minju Kim, Seongeun Gu, Jeoung Eun Lee, Yunjin Park, Su Bin Lim, Ji Young Mun, Sangyong Jung, Dong Ryul Lee, Junghyun Jo

“…Methods The 3D hSkMOs were generated from hPSC and exhibited structurally and functionally mature muscle fibres and spinal‐derived neurons including motor neurons and interneurons. …”
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Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain by Yeojin Kim, Aleksandar Lučić, Christopher Lenz, Frederic Farges, Martin P. Schwalm, Krishna Saxena, Thomas Hanke, Peter G. Marples, Jasmin C. Aschenbrenner, Daren Fearon, Frank von Delft, Andreas Krämer, Stefan Knapp

“…The high-resolution structural data and observed binding modes across the different sites highlight the versatility of the PRY-SPRY domain as a target for small-molecule intervention. …”
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El principio de universalización y la razón práctica (2a. parte) by Osvaldo Guariglia

“…In this paper I show, first, (I) a scheme of the universalization principIe in order to clarify not only its logical structure but the different concepts that must be specified in each case so that the principIe can be applied significantly. …”
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A Nutritional Supplement Containing Curcumin C3 Complex, Glucosamine, and Chondroitin Alleviates Osteoarthritis in Mice and Canines by Enpei Zheng, Ting Cen, Ye Ma, Ziyuan Weng, Chuanheng Jiang, Luxi Hou, Jun Leng, Changmin Hu

“…According to our findings, the administration of C3GC was determined to preserve subchondral microarchitectural structure integrity (<i>p</i> < 0.05) and resulted in better motor function in comparison with GC. …”
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Validation of the World Health Organization’s Disability Assessment Schedule 2.0 for children with mental disorders in specialized health-care services by Lina Díaz-Castro, Miriam Arroyo-Belmonte, Paloma Suárez-Brito, María Elena Márquez-Caraveo, Consuelo Garcia-Andrade

“…The validation of reliable assessment tools is crucial for identifying functional impairments and guiding interventions in this population. …”
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CORRELATION BETWEEN MRI-BASED BRAIN VOLUME CHANGES AND COGNITIVE DECLINE IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT: A PROSPECTIVE OBSERVATIONAL STUDY. by Karishma Khushalrao Surpam

“…This study aimed to assess the relationship between structural brain volume changes and cognitive decline among patients diagnosed with Mild Cognitive Impairment (MCI). …”
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An overview of the integration and development trends between arts and psychotherapy by Yuxing Xie, Xianhua Sun

“…Its core mechanism lies in promoting individuals to achieve emotional release, cognitive reconstruction, and social function recovery through the creative expression of art forms, which has given rise to the important practical field of art therapy. …”
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Current Understanding of Pulmonary Fibrosis: Pathogenesis, Diagnosis, and Therapeutic Approaches by Dinglu Cui, Xiangguo Che, Rongxian An, Lei Li, Xinying Cui, Long Jiang, Jingchun Jin

“…It is characterized by proliferation of fibroblasts and deposition of a large amount of extracellular matrix, accompanied by inflammatory damage and structural destruction, caused by various reasons. The prognosis of PF is poor, and the average survival time after diagnosis is 2.5–3.5 years. …”
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Mechanism of Modified Tongyou Decoction and Its Separated Formulas Inhibiting Vasculogenic Mimicry in Esophageal Cancer TE-1 Cells via NF-κB/HIF-1α Axis by Qian Wang MS, Yingying Tian MS, Lingyu Kong MD, Zeyi Chen MS, Xin Yan PhD, Chenxi Wu PhD, Huijuan Cao PhD, Fanwu Wu PhD, Yongsen Jia PhD, Prof.

“…Hypoxia stimulation promoted formation of reticular structure of cells after 6 hours. The structure disappeared after the 4 medications’ activity. …”
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Biomechanics of walking before and after surgical treatment of damaged menisci of the knee joint by D. V. Skvortsov, S. N. Churkin, A. A. Akhpashev, D. S. Agzamov, A. S. Kanaev, A. N. Lobov, V. P. Plotnikov, A. I. Zhuravleva

“…In the available literature there are a few articles devoted to the study of the KJ function when walking before and after meniscus resection. …”
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Spatiotemporal characterization of the dynamic changes in the intestinal microbiota of Taihe Silky Fowl by Wentao Li, Haoneng Guo, Youping Wu, Yizhen Wang, Zeqing Lu

“…Conclusions In conclusion, the diversity, structure, composition, community relationships and functions of the intestinal microbiota in Taihe Silky Fowl dynamically changed with age in different intestinal regions.…”
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Postbiotics Regulate Intestinal Microbiota and Reduce Amyloid β-Protein Deposition in the Brain, Thereby Ameliorating Cognitive Impairment in Rats with Alzheimer’s Disease by XIAO Ling, TANG Linlin, SONG Xiaoyan, ZHANG Yihua, HAN Xuemei, LÜ Houjiao, LIANG Wu, WANG Yanping, GENG Weitao, JIA Longgang

“…The results showed that all three postbiotics could significantly improve the learning and memory capacities of AD rats, significantly reduce the content of Aβ in hippocampal tissues, and decrease the LPS levels in feces, serum, and hippocampal tissues and the relative mRNA transcription levels of TLR4, NLRP3 and MyD88 in brain tissues. Intervention with the postbiotics regulated the structure and composition of the intestinal microbiota. …”
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