Algorithms of optimization and standardization of surgical care in destructive forms of Charcott foot by K. A. Koreyba, E. P. Krivoshchekov, N. A. Lysov, L. N. Gatina, P. S. Lukin

“…The developed approach to the reconstruction of bone elements of the foot ensures an increase in the efficiency of regenerative processes of bone structures. 2. The introduction of this technique significantly reduces the rehabilitation period for patients with restoration of the supporting function of the lower extremities due to targeted surgical intervention in the area of affected tissues.…”
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Evaluation of additional points in the 24-2C visual field test in pre-perimetric glaucoma by Gökhan Çelik, Tuncay Karaçocuk, Furkan Çiftci

“…The relationship between structural and functional parameters was statistically evaluated. …”
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Epigenetic regulatory protein chromobox family regulates multiple signalling pathways and mechanisms in cancer by Weiyu Su, Weiwen Wang, Guanghui Zhang, Lianhe Yang

“…This review aims to succinctly delineate the composition, structure, function, and expression of CBXs within tumour cells, with an emphasis on synthesizing and deliberating the CBXs-mediated activation of intracellular signalling pathways and the intricate mechanisms governing tumourigenesis and progression. …”
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Separable sustained and selective attention factors are apparent in 5-year-old children. by Mette Underbjerg, Melanie S George, Poul Thorsen, Ulrik S Kesmodel, Erik L Mortensen, Tom Manly

“…The results are discussed in light of contemporary models of attention function. Given the potential advantages of early intervention for attention difficulties, the findings are of clinical as well as theoretical interest.…”
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The molecular etiology and treatment of glucocorticoid-induced osteoporosis by Cheng-Huan Peng, Wen-Ying Lin, Kuang-Ting Yeh, Ing-Ho Chen, Wen-Tien Wu, Ming-Der Lin

“…When bone formation and resorption are out of balance, abnormalities in bone structure or function may occur. Excess glucocorticoids disrupt the bone homeostasis by promoting osteoclast formation and prolonging osteoclasts' lifespan, leading to an increase in bone resorption. …”
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Advanced smart assistance with enhancing social interaction and daily activities for visually impaired individuals using deep learning with modified seagull optimization by Sana Alazwari, Hussah Nasser AlEisa, Mohammed Rizwanullah, Radwa Marzouk

“…Damage detection is a common approach in infrastructure that combines steel and concrete reinforcement to achieve optimal durability and structural strength. These bridges, designed to withstand diverse loads such as seismic forces, traffic weight, and environmental factors, are significant for maintaining structural integrity. …”
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Immunometabolism in the Aging Heart by Kranti A. Mapuskar, Barry London, Zeb R. Zacharias, Jon C.D. Houtman, Bryan G. Allen

“…Structural, functional, and molecular‐level changes in the aging heart are influenced by a dynamic interplay between immune signaling and cellular metabolism that is referred to as immunometabolism. …”
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A literature review on role of physical activity in the prevention and treatment of depression by Albert Lompart, Michał Wabiszewicz, Albert Kosarewicz, Łukasz Woźniak, Patrycja Krysiak

“…It critically assesses recent evidence and identifies the most effective exercise interventions by systematically analysing studies published between 2017 and 2025. …”
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Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways by Ge Gong, Xiangxuan Chen, Xinghu Zhang, Jian Yin, Wenhui Wan

“…In a mouse model, cardiac function deteriorated and ventricular structural changes were observed 14 days post-myocardial infarction relative to controls. …”
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Nanotherapies Based on ROS Regulation in Oral Diseases by Xin Luo, Yanli Zhang, Yuting Zeng, Dehong Yang, Zhiyan Zhou, Ziting Zheng, Ping Xiao, Xian Ding, Qianlin Li, Jiaping Chen, Qianwen Deng, Xincen Zhong, Sijie Qiu, Wenjuan Yan

“…The concentration of reactive oxygen species (ROS) within cells has been demonstrated as a pivotal player in modulating these intricate pathological processes, exerting significant roles in restoring oral functionality and maintaining tissue structural integrity. …”
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LncRNAs Regulate Vasculogenic Mimicry in Human Cancers by Eloísa Ibarra-Sierra, Mercedes Bermúdez, Carlos Esteban Villegas-Mercado, Macrina B. Silva-Cázares, César López-Camarillo

“…Future directions for research focused on deciphering their function in VM are delineated. Finally, the potential of selected lncRNAs as novel therapeutic targets in RNA-based molecular interventions is also discussed.…”
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Elevated septal native T1 time in cardiac magnetic resonance imaging suggesting myocardial fibrosis in young kidney transplant recipients by Tim Alexander Ubenauf, Jeannine von der Born, Rizky I. Sugianto, Carl Grabitz, Elena Lehmann, Nima Memaran, Nele Kanzelmeyer, Jan Falk, Nigar Babazade, Samir Sarikouch, Diane Miriam Renz, Bernhard Magnus Wilhelm Schmidt, Anette Melk

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Comprehensive characterization of multi-omics landscapes between gut microbial metabolites and the druggable genome in sepsis by Jun Liu, Tong Li, Li Xin, Xingyu Li, Jianbo Zhang, Peng Zhu

“…Emerging evidence implicates gut microbial metabolites in modulating host immunity, but the specific interactions between these metabolites and host druggable targets remain poorly understood.MethodsWe utilized a systems biology framework integrating genetic analyses, multi-omics profiling, and structure-based virtual screening to systematically map the interaction landscape between human gut microbial metabolites and druggable G-protein-coupled receptors (GPCRs), ion channels (ICs), and kinases (termed the “GIKome”) in sepsis. …”
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Study protocol for an observational research study with an embedded N-of-1 design: Increasing the availability of goal-oriented cognitive rehabilitation for people living with deme... by Caoimhe Hannigan, Antoine Lemercier, Garret McDermott, Helena Lydon, Sean P Kennelly, Michelle Kelly

“…<h4>Background</h4>Goal-Oriented Cognitive Rehabilitation (GREAT-CR) is an evidence-based early intervention for people with mild-moderate dementia that improves goal attainment and functional outcomes. …”
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The Emotional and Social Impact of Hearing Loss by Harsh Nawal, Diptanshu Mukherjee, Shamima Yasmin, Saumendra Nath Bandyopadhyay

“…   Introduction Hearing loss affects not only auditory function but also significantly impacts a person's emotional and social functions. …”
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The health care needs of multidimensional frail elderly patients with multimorbidity in primary health-care settings: a qualitative study by Linlin Zhao, Bingjie Chang, Qinghua Hu, Xiaolei Chen, Juan Du, Shuang Shao

“…Appropriate policies and measures should be taken, such as integrating multidimensional frailty assessments into current multimorbidity management protocols, developing personalized interventions centered on patient needs, conducting family function assessments and caregiver training programs, and enhancing the integration of social resources.…”
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Auditory processing and its cognitive correlates in older adults with mild cognitive impairment by Leelavathi Thamizhmani, Kanaka Ganapathy, Hari Prakash Palaniswamy, Arivudai Nambi Pitchaimuthu, Prabha Adhikari M. R.

“…Research should also examine the impact of tailored auditory training on cognitive function in MCI to inform interventions. Trial registration The study was registered in the Clinical Trials Registry of India (CTRI/2023/06/054277) on 21/06/2023 ( http://ctri.nic.in/ ).…”
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Preserving heritage through a novel framework for the adaptive reuse of Mediterranean earthen houses by Ihab Khalil, Doğa Üzümcüoğlu

“…Four representative cases —Alhambra in Spain, Ghadames in Libya, KTMMOB Chamber of Architects Main Building in North Cyprus, and Sheikh Hilal Beehive Houses in Syria— were analyzed based on six key dimensions: preservation of structural and aesthetic integrity, functional adaptation and minimal intervention, environmental efficiency and structural reinforcement, flexibility and adaptability, community engagement and cultural relevance, and compliance with documentation and economic revitalization. …”
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Predicting depression risk in middle-aged and elderly adults in China using CNN-BiLSTM-Attention mechanism and LSTM+SHAP framework by Shengxian Bi, Gang Li, Huawei Tan, Yingchun Chen, Dandan Guo

“…Dynamic time windows were employed to handle time data sequences of inconsistent lengths, aligning with the structure of public databases. SHAP (SHapley Additive exPlanations) analysis was used to quantify and visualize the impact of each feature on the prediction results. …”
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Decoding Schizophrenia: How AI-Enhanced fMRI Unlocks New Pathways for Precision Psychiatry by Valeria Di Stefano, Martina D’Angelo, Francesco Monaco, Annarita Vignapiano, Vassilis Martiadis, Eugenia Barone, Michele Fornaro, Luca Steardo, Marco Solmi, Mirko Manchia, Luca Steardo

“…This manuscript explores how the integration of these technologies has unveiled key insights into schizophrenia’s structural and functional neural anomalies. fMRI research highlights disruptions in crucial brain regions like the prefrontal cortex and hippocampus, alongside impaired connectivity within networks such as the default mode network (DMN). …”
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