Conformational Analyses of the AHD1-UBAN Region of TNIP1 Highlight Key Amino Acids for Interaction with Ubiquitin by Michael L. Samulevich, Liam E. Carman, Rambon Shamilov, Brian J. Aneskievich

“…IDPs move through a repertoire of three-dimensional structures rather than being in one set conformation. …”
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Intermittent fasting inhibits the development of colorectal cancer in APCMin/+ mice through gut microbiota and its related metabolites by Jia Chen, Rishun Su, Yulong He, Jiong Chen

“…Subsequently, 16S rRNA sequencing and untargeted metabolomics were employed to analyze alterations in fecal microbial community structure and metabolic profiles following the fasting intervention. …”
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Sex differences in schizophrenia: symptomatology, treatment efficacy and adverse effects by Ivi Moniem, Vasilios Kafetzopoulos

“…Neurobiologically, men with SZ exhibit more extensive structural brain abnormalities and cognitive impairment (especially in memory), whereas women benefit from a degree of neuroprotection possibly mediated by estrogen and distinct gene expression patterns. …”
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Undervalued essential work and lacking health literacy as determinants of COVID-19 infection risks: a qualitative interview study among foreign-born workers in Sweden by Annika Rosengren, Kristina Jakobsson, Mia Söderberg, Maria Magnusson, Juhaina Swaid

“…The respondents fulfilled important societal functions, but their work was undervalued due to low job status, and they had little influence on improving safety at work. …”
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The translational power of Alzheimer’s-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history by Cristina Dolciotti, Marco Righi, Eleonora Grecu, Marcello Trucas, Cristina Maxia, Daniela Murtas, Andrea Diana

“…BOs derived from patient-specific induced pluripotent stem cells (iPSCs) mimic the structural and functional complexities of the human brain. …”
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Social support and depression among community dwelling older adults in Asia: a systematic review by Tengku Amatullah Madeehah Tengku Mohd, Raudah Mohd Yunus, Farizah Hairi, Noran N Hairi, Wan Yuen Choo

“…Social support was found to be measured by multiple components, most commonly through a combination of structural and functional constructs. Perceived social support is more commonly measured compared with received social support. …”
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Cardiomyopathies and a brief insight into DOX-induced cardiomyopathy by Sampat Singh Tanwar, Sumeet Dwivedi, Sheema Khan, Seema Sharma

“…Abstract Background Cardiomyopathy is a heterogeneous group of myocardial disorders characterized by structural and functional abnormalities of the heart muscle. …”
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Age-related disturbances in rest-activity rhythms and integrity of the hippocampal network: An exploratory study by Aurore Jouvencel, Bixente Dilharreguy, Marion Baillet, Karine Pérès, Jean-François Dartigues, Hélène Amieva, Willy Mayo, Gwenaëlle Catheline

“…A segmentation of the hippocampus and its related structures was used to assess volumes and functional connectivity in this network based on anatomical and resting state functional data. …”
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Holistic Education for a Resilient Future: An Integrated Biomimetic Approach for Architectural Pedagogy by Lidia Badarnah

“…Bloom’s Taxonomy provides a scaffold for learning progression, while the Function–Structure–Behavior (FSB) schema enhances the establishment of cross-disciplinary bridges to enable students to address complex design challenges. …”
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Strategies for Construction and Optimization of the Ecological Security Pattern for Human Settlements in the Wuding River Basin by Xiaomeng WANG, Anrong DANG, Biao TONG, Xinyi LIU

“…This framework extends westward and northward from the southeastern region of the basin, forming a hierarchical and interconnected ecological spatial structure that strengthens ecosystem stability and enhances service functions. …”
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Surgical implants in animal models for male and female infertility: A translational approach by S. Bharath, A.S. Vickram, B. Bhavani Sowndharya, C. Prasanth, D. Jenila Rani, G. Gulothungan, Hitesh Chopra, Tabarak Malik

“…Structured Abstract: Background: Infertility remains a significant challenge in reproductive medicine, affecting both men and women. …”
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Mechanism of Electroacupuncture at Baihui and Shenting Alleviating Cerebral Ischemia-reperfusion Injury via Regulating BNIP3L-Mediated Mitophagy by ZHONG Xiaoyong, LI Cheng, WANG Fang, CHEN Bin, LIANG Hui, RUAN Su

“…However, the neurological scores of rats in the electroacupuncture group reduced after electroacupuncture intervention, which was significantly different from the model group and electroacupuncture+3-MA group (<italic>P</italic>&lt;0.05). 2) The results of HE staining showed that the cell body of neurons in the sham operation group was large, polygonal (multiple protrusions), the nucleus was lightly colored, and the characteristic structure of Nissl body could be seen in the cytoplasm. …”
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Immunotherapy targeting isoDGR‐protein damage extends lifespan in a mouse model of protein deamidation by Pazhanichamy Kalailingam, Khalilatul‐Hanisah Mohd‐Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca EK MacPherson, Evangelia Litsa Tsiani, Deborah D O'Leary, Kah Leong Lim, I Hsin Su, Yong‐Gui Gao, A Mark Richards, Raj N Kalaria, Christopher P Chen, Neil E McCarthy, Siu Kwan Sze

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Advances in the molecular mechanisms of zinc-finger transcription factors in neurodevelopmental disorders by Hailin Wang, Ying Yang, Ziwei Ni, Xiaoting Qiao, Yaqian Guo, Xiaomin Wang, Duo Cao, Yayun Wang, Cailian Ruan

“…This review aims to elucidate the structure and molecular functions of the BCL11 gene family, discuss its impact on the development of the central nervous system, and explore its association with neurodevelopmental disorders.…”
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Meaning in Life Among Aged People: A Qualitative Study of an Institutionalized Elderly Sample by Lăcrămioara Cojocaru, Camelia Soponaru, Daniela Muntele-Hendreș, Ciprian Ceobanu

“…Daily life objectives, including short-term goals like maintaining routines or anticipating family visits, along with preserving functional independence, provided structure and immediate purpose for many participants. …”
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Striving to integrate self-management into daily life: a qualitative meta-synthesis of the perspectives and experiences from head and neck cancer survivors by Hao Zhang, Li Yin, Qing Yang, Aiping Wang, Linyu Xu, Jianxia Lyu

“…This integration revealed 3 primary themes and 10 subthemes, specifically: (1) the management of disease-related and treatment-related symptoms and functional alterations in HNC, exploring self-management strategies such as coping with and monitoring physical and mental symptoms and adjusting to modifications in fundamental operations; (2) barriers and facilitators in the integration process of self-management, including psychological, emotional and cognitive disorders, the impact of symptom burden on patients’ motivation and capacity for self-management, structural impediments and facilitators; and (3) challenges in incorporating self-management into daily life and strategies for effective implementation, encompassing acceptance and adaptation as strategies for coping and thriving, proactive issue resolution, self-motivation and the employment of a diverse array of targeted strategies emphasising recovery.Conclusions Patients diagnosed with HNC must engage in extensive self-management throughout diagnosis and treatment, encountering numerous challenges when integrating self-management practices into their daily lives. …”
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IL-1 Superfamily Across 400+ Species: Therapeutic Targets and Disease Implications by Weibin Wang, Dawei Li, Kaiyong Luo, Baozheng Chen, Tingting Hao, Xuzhen Li, Dazhong Guo, Yang Dong, Ya Ning

“…Important results show that, although IL-1 ligands expanded significantly over the evolution of mammals, their corresponding receptors remained remarkably structurally conserved. Identifying both lineage-specific adaptations and evolutionarily conserved residues provides vital information for treatment design. …”
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Clinical decision support in the electronic health record: a primer for antimicrobial stewards and infection preventionists: work smarter so end users don’t work harder by Mary Rochelle Smith, Julie J. Lee, Marisa Holubar, Jorge L. Salinas, Mindy M. Sampson, Richard J. Medford, Amy Chang

“…This primer article aims to provide ASP and IP professionals with a practical framework for the development, design, and evaluation of CDS interventions. Setting: Large academic medical center design: Established frameworks of CDS evaluation, “Five Rights” of CDS and the “Ten Commandments of Effective Clinical Decision Support”, were applied to two real-world examples of CDS tools, a Vancomycin Best Practice Advisory and a Clostridioides Difficile order panel, to demonstrate a structured approach to developing and enhancing the functionality of ASP/IP CDS interventions to promote efficacy and reduce unintended consequences of CDS. …”
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Concept and Characteristic of Urban Landscape Layering, and Design Approach Towards Urban Regeneration by Jinyu ZHANG, Yuan XU, Yufan ZHU

“…Urban landscape evolves through a nonlinear process of accumulation, with physical structures, functions, and meanings continuously transforming. …”
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Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology by Jiaying Yang MM, Yuancai Liu MM, He Yao MM, Mengying Sun MM, Yangbo Tong MM, Guanjun Ma MM, Zhuo Chen MD, Xiang Qian MD, Aiqin Zhang MD

“…Objective: To observe the clinical efficacy of Dendrobium officinale in the treatment of radiotherapy-induced oral mucositis in nasopharyngeal carcinoma patients, and to explore its regulating effect on immune function and oral microbiota by comparing immune-related factors and oral microbiota before and after the intervention. …”
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