A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…., Walnut Creek, CA, USA; 12Private Practice, San Francisco, CA, USACorrespondence: Jon E Block, Private Practice, 2210 Jackson Street, Ste. 401, San Francisco, CA, 94115, USA, Tel +1 415-775-7947, Email jb@drjonblock.comBackground: There is renewed interest in the intervertebral disc as a target for treatments aimed at ameliorating lumbar discogenic pain by restoring and preserving the natural structure and function of this component of the vertebral motion segment.Methods: Using a modified Delphi methodology involving a panel of 11 experts, we developed a simple, understandable clinical algorithm to serve as a foundation for objective decision making regarding the diagnosis and treatment of lumbar discogenic pain throughout the entire continuum of care. …”
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Effect of low-moderate intensity traditional Chinese exercises combined with acupuncture on patients with stable chronic obstructive pulmonary disease: study protocol for a randomi... by Hongxia Duan, Yidie Bao, Linhong Jiang, Peijun Li, Yingqi Wang, Yuchen He, Xinliao Deng, Weibing Wu, Wei Zhang, Xiaodan Liu, Xiaodan Liu

“…Secondary outcomes will include lung function, degree of dyspnea, diaphragmatic function, respiratory muscle strength, skeletal muscle structure, skeletal muscle function, psychological states, and quality of life. …”
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Characteristics of non-suicidal self-injury and its associations with gender minority stressors among Hungarian transgender and gender diverse adults by Banu C. Ünsal, Zsolt Demetrovics, Melinda Reinhardt

“…Those who engaged in NSSI previously were significantly younger compared to those without NSSI. Structural equation model (SEM), examining the associations among gender minority stressors and functions of NSSI, revealed that proximal stressors mediated the link between distal stressors and intrapersonal functions of NSSI. …”
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Effect of aerobic exercise combined with meditation on cognitive frailty: study protocol for a parallel group randomised controlled trial by Wenju Wang, Lei Yang, Feng Chen, Weilin Liu, Tao Jiang, Sijia Xia, Jingfang Zhu, Minguang Yang, Qing Xiang

“…The primary outcomes will include the Edmonton Frailty Scale, while secondary outcomes will encompass evaluations of cognitive functions (including global cognitive function, memory, attention, executive function and visuospatial abilities), physical performance (measured by gait speed and lower extremity strength), subjective experiences (such as fatigue, quality of life, mindfulness, mood and sleep quality), as well as structural and functional MRI assessments and serum biomarkers. …”
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Cardiac Magnetic Resonance in the Assessment of Atrial Cardiomyopathy and Pulmonary Vein Isolation Planning for Atrial Fibrillation by Nicola Pegoraro, Serena Chiarello, Riccardo Bisi, Giuseppe Muscogiuri, Matteo Bertini, Aldo Carnevale, Melchiore Giganti, Alberto Cossu

“…Advanced imaging techniques, particularly cardiac magnetic resonance (CMR) imaging, have emerged as pivotal in the detailed assessment of atrial structure and function. CMR facilitates the precise measurement of left atrial volume and morphology, which are critical predictors of AF recurrence post-intervention. …”
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Birds, Bees, and Botany: Measuring Urban Biodiversity After Nature-Based Solutions Implementation by Mónica Q. Pinto, Simone Varandas, Emmanuelle Cohen-Shacham, Edna Cabecinha

“…Plant diversity also improved, with a rise in native and RELAPE-listed species (5.23%). Functional group analyses underscored the importance of vegetative structure in supporting varied foraging and nesting behaviours. …”
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Transient receptor potential channels in dental inflammation and pain perception: A comprehensive review by Varunya Chantadul, Nattapon Rotpenpian, Tawepong Arayapisit, Aree Wanasuntronwong

“…These inflammatory conditions notably contribute to oral health challenges, often leading to sharp pain, dull aches, and compromised functionality. Pharmacological interventions and emerging strategies aimed at modulating TRP channel activity are critically evaluated. …”
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Divergence and convergence in epiphytic and endophytic phyllosphere bacterial communities of rice landraces by Pratibha Sanjenbam, Deepa Agashe

“…ABSTRACT Phyllosphere-associated microbes can significantly alter host plant fitness, with distinct functions provided by bacteria inhabiting the epiphytic (external surface) vs endophytic niches (internal leaf tissue). …”
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Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity by Brooke Mulrenin, Bryant A. Seamon, Carrie Cormack, Kimberly Lane Kascak, Cynthia Dodds

“…Person misfit did not degrade item measures or model statistics. Differential item functioning (DIF) was noted for the three easiest items on specific days. …”
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Identification and bioinformatics analysis of the DUS gene in Eimeria media by Yijin Zou, Yiyan Wang, Diyi Duan, Xun Suo, Yuanyuan Zhang

“…Additionally, bioinformatics analysis provided insights into the evolutionary trends and structural characteristics of the DUS gene across different species, suggesting a broader biological significance. …”
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Reactive Nitrogen Species and Fibrinogen: Exploring the Effects of Nitration on Blood Clots by Francesca Nencini, Serena Borghi, Elvira Giurranna, Ilenia Barbaro, Niccolò Taddei, Claudia Fiorillo, Matteo Becatti

“…This review explores the structural and functional consequences of fibrinogen nitration, with a focus on its impact on clot formation, morphology, mechanical stability, and fibrinolysis. …”
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Diagnostic Tools Before Thyroidectomy: A Surgical Perspective by Flaviu Mureşan, Ovidiu Vasile Fabian, Emilia Maria Pătruţ, Olga Hilda Orăşan, Ana Valea, Radu Bogdan Popescu

“…Before performing a thyroidectomy, a range of diagnostic studies is typically conducted to evaluate thyroid function and structure. Ultrasound and elastography are employed to assess the gland’s morphology and to identify nodular goiters that may necessitate fine-needle aspiration cytology (FNAC) or surgical intervention. …”
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Biomarker Evolution in Pediatric SMA: Insights from CSF pNF-H Dynamics and SMN2 Copy Number During Nusinersen Therapy by Mihaela Badina, Gabriel Cristian Bejan, Andrada Mirea, Corina Sporea, Madalina Cristina Leanca, Georgiana Nicolae, Ioana Elena Cioca, Maria Veronica Morcov, Angelo Pellegrini, Elena-Nicoleta Bordea

“…This study evaluates cerebrospinal fluid (CSF) phosphorylated neurofilament-heavy chain (pNF-H) levels as predictive markers of motor function in 73 pediatric SMA patients undergoing nusinersen treatment. pNF-H, a structural component of neurons, is released into the CSF and serum during neuronal damage or degeneration. …”
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Addressing Hybrid Confounder Issue for Causal Session-Based Recommendation by Quan Li, Xinhua Xu, Jinjun Liu, Guangmin Li

“…First, the conditional probability about user preference given a user sequence is solved by intervention and structural equation. Then, implicit environmental features are learned with observation sequence data. …”
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Knockout of Apolipoprotein E in rabbit promotes premature intervertebral disc degeneration: A new in vivo model for therapeutic approaches of spinal disc disorders. by Anja Beierfuß, Hermann Dietrich, Christian Kremser, Monika Hunjadi, Andreas Ritsch, Thomas Rülicke, Claudius Thomé, Demissew Shenegelegn Mern

“…Intervertebral disc (IVD) degeneration that accelerates the loss of disc structural and functional integrities is recognized as one of the major factors of chronic back pain. …”
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Trends and Challenges of Chronic Occupational Morbidity in Ukraine: A Sectoral Analysis and Preventive Strategies by Iryna Mezentseva, Olena Kuzmenko, Sergij Vambol, Serhii Mezentsev, Vladyslava Vambol

“…High-risk industries, particularly the mining sector, exhibit alarming rates of chronic occupational diseases, mainly affecting the respiratory system, musculoskeletal structure, and auditory functions. This study aims to analyze trends and causes of chronic occupational morbidity in Ukraine from 2016 to 2022, utilizing statistical data and quantitative analysis. …”
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Metric invariance and psychometric properties of assessment of attitudes toward inclusion of students with disabilities (AISDPE) in Physical Education by Serafín Delgado-Gil, Noelia Mayordomo-Pinilla, Santiago Gómez-Paniagua, Carmen Galán-Arroyo, Pedro R. Sánchez Olivares-Toledo, Jorge Rojo-Ramos

“…Results: showed a seventeen-item bifactor structure with excellent goodness-of-fit and reliability indices. …”
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Perspectives and Limitations of Mesenchymal Stem Cell–Based Therapy for Corneal Injuries and Retinal Diseases by Barbora Hermankova, Eliska Javorkova, Katerina Palacka, Vladimir Holan

“…The eye represents a highly specialized organ, with its main function being to convert light signals into electrical impulses. …”
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Motivating factors for individuals aged 40–70 years with type-2 diabetes to engage in physical activity by Sólfríð A. Skoradal, Sarita Vesturdal Vesturtún, May Britt Skoradal, Annika Helgadóttir Davidsen

“…IntroductionType-2 diabetes (T2D) is a chronic disease resulting from inadequate insulin production or impaired insulin function. Globally, T2D poses a significant health burden with various complications. …”
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Neuronal plasticity and its role in Alzheimer’s disease and Parkinson’s disease by Israt Jahan, Mohammad Harun-Ur-Rashid, Md. Aminul Islam, Farhana Sharmin, Soad K. Al Jaouni, Abdullah M. Kaki, Samy Selim

“…Neuronal plasticity, the brain’s ability to adapt structurally and functionally, is essential for learning, memory, and recovery from injuries. …”
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