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961
Diabetic Enteropathy: From Molecule to Mechanism-Based Treatment
Published 2018-01-01“…Arguably, the most common microvascular complication is neuropathy, leading to deleterious changes in both the structure and function of neurons. Amongst the various neuropathies with the highest symptom burden are those associated with alterations in the enteric nervous system, referred to as diabetic enteropathy. …”
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962
Research progress on brain network imaging biomarkers of subjective cognitive decline
Published 2025-02-01“…PurposeSubjective cognitive decline (SCD) is an early manifestation of the Alzheimer’s disease (AD) continuum, and accurately diagnosing SCD to differentiate it from neurotypical aging in older adults is a common challenge for researchers.MethodsThis review examines and summarizes relevant studies regarding the neuroimaging of the AD continuum, and comprehensively summarizes and outlines the SCD clinical features characterizing along with the corresponding neuroimaging changes involving structural, functional, and metabolic networks.ResultsThe clinical characteristics of SCD include a subjective decline in self-perceived cognitive function, and there are significant imaging changes, such as reductions in gray matter volume in certain brain regions, abnormalities in the integrity of white matter tracts and diffusion metrics, alterations in functional connectivity between different sub-networks or within networks, as well as abnormalities in brain metabolic networks and cerebral blood flow perfusion.ConclusionThe 147 referenced studies in this paper indicate that exploring the structural, functional, and metabolic network changes in the brain related to SCD through neuroimaging aims to enhance the goals and mission of brain science development programs: “Understanding the Brain,” “Protecting the Brain,” and “Creating the Brain,” thereby strengthening researchers’ investigation into the mechanisms of brain function. …”
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963
Comparing the effects of physical activity and cognitive training on cognitive performance, physical fitness, and mental health in 9- to 10-year-old children: a randomized clinical...
Published 2025-06-01“…The study found that all cognition and mental health parameters improved significantly in the PA, CT, and PA+CT groups than in the control group (p < 0.05), with the strongest effects in PA+CT.ConclusionThis study demonstrates that structured interventions administered four times each week can differentially improve physical fitness, cognition, and mental health outcomes in school-aged children. …”
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964
Probiotics in Sports: Modulating the Microbiome for Performance and Health
Published 2025-07-01“…ConclusionsThe gut microbiome is a key determinant of systemic health. Targeted diet, structured physical activity, and personalized probiotic use can optimize microbiota function. …”
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965
The Efficacy and Mechanism of Qinghua Jianpi Recipe in Inhibiting Canceration of Colorectal Adenoma Based on Inflammatory Cancer Transformation
Published 2023-01-01“…And its mechanism is related to the regulation of intestinal flora structure and abundance, short-chain fatty acid metabolism, intestinal barrier function, and inflammatory pathways.…”
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966
Multimodal dynamic retinal vessel analysis offers new insights in microvascular defects in Fabry’s disease
Published 2025-06-01“…This principle of multimodal analysis of dynamic retinal vascular behavior has been applied to demonstrate specific structural and functional retinal microvascular changes in Fabry’s disease. …”
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967
Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease
Published 2025-02-01“…Defects in retinal structure and function are also present in the R6/2 and R6/1 HD transgenic mouse models that contain a gene fragment to express mHTTex1. …”
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968
Stimuli‐responsive magnesium‐based materials for biomedical applications: A review
Published 2025-02-01“…However, there is a lack of systematic summaries on the “composition‐structure‐function” relationships when Mg‐based materials are applied in various physiological scenarios. …”
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969
Neonatal scrotochesis following artificial rupture of membrane in breech delivery
Published 2025-07-01“…Birth trauma refers to structural or functional impairments in newborns caused by mechanical forces during labour and delivery, with breech presentation significantly increasing the risk of neonatal injuries. …”
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970
Reversal of glial and neurovascular markers of unhealthy brain aging by exercise in middle-aged female mice.
Published 2011-01-01“…Brain vascular casts revealed exercise-induced structural modifications associated with improved endothelial function in the periphery. …”
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971
Impacts of Climate Change on the Plant Water Interactions
Published 2023“…Climate change has an impact on ecosystem structure and function globally by altering the relationships between plants and soil organisms. …”
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972
Aesthetic Rehabilitation of Oligodontia in Primary Dentition with Adhesive Partial Denture
Published 2013-01-01“…Thus, the congenitally absence of teeth may trigger a shift in the balance of the occlusion, promoting disharmony in the structures of the maxilla-mandibular system. However, some interventions are possible to be performed in these cases even in pediatric patients, to redirect growth, preventing growth deviations and reestablishing the aesthetic. …”
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973
Circular economy strategies for adaptive reuse of residential building
Published 2021-06-01“…However, the traditional approach of carrying out timely interventions aimed at responding to individual problems, be they of a structural, energetic, functional nature, relating to the building, the context or the single component is not entirely effective in terms of reformulation of the building characteristics. …”
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974
Gut microbiota’s role in the enhancement of type 2 diabetes treatment by a traditional Chinese herbal formula compared to metformin
Published 2025-05-01“…Consequently, these findings suggest that CCM offers a promising therapeutic strategy for T2DM, and further provide valuable insights into potential probiotic candidates (such as Bacteroidetes spp., Akkermansia spp., and Parabacteroides spp.) and newly identified functional pathways (such as chondroitin sulfate degradation, geraniol degradation, biotin biosynthesis, colonic acid building blocks biosynthesis, and the biosynthesis of vancomycin group antibiotics) that could be targeted for therapeutic intervention.…”
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975
Microbial metabolites and immune modulation
Published 2024-12-01“…The human microbiota, a complex ecosystem of microorganisms, has garnered significant attention for its profound influence on host health. Beyond their structural roles, these microbes produce a diverse array of bioactive metabolites that interact with the host immune system. …”
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976
Protecting health facilities: design options for armed conflict and climate change disasters
Published 2023-03-01“…Hospital facility designs are essential to maintaining function during times of disaster. For hospitals to remain open during emergencies, their structures must resist forces from many types of hazards such as earthquakes, hurricanes, flooding, and even societal hazards, such as war. …”
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977
Chordae tendineae rupture: a rare cause of tricuspid regurgitation following coronary artery bypass grafting
Published 2025-07-01“…However, intraoperative transesophageal echocardiography, even during routine isolated coronary artery bypass grafting, can be a valuable tool in differentiating between functional and structural causes of post-cardiopulmonary bypass tricuspid regurgitation, allowing for prompt surgical intervention when required. …”
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978
Perinatal SSRI exposure impacts innate fear circuit activation and behavior in mice and humans
Published 2025-05-01“…In mice and humans, early-life SSRI exposure alters the offspring’s brain structure and is associated with anxiety and depression-related behaviors beginning in puberty. …”
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979
Who’s Who & Whereabouts
Published 2022-12-01“…We describe the system’s structure, functionality, and ease of use. La surveillance des populations d’espèces menacées est essentielle à la compréhension des dangers qu’elles rencontrent et pour la gestion des interventions mises en place afin d’assurer leur survie à long terme. …”
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980
Evaluating Teaching Effectiveness and Student Performance Across Diverse Courses: An Analysis of Final Exam Scores and Teaching Techniques
Published 2025-04-01“…Bayesian analysis confirmed that the differences are statistically significant: the first discriminant function explains 86.8% of the variation, p < 0.001; the second function explains 13.2%, p < 0.001. …”
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