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941
Efficacy and safety of stem cells in the treatment of glaucoma: systematic review and meta-analysis based on animal experiments
Published 2025-07-01“…Emerging preclinical evidence further highlights dual neuroprotective mechanisms (i.e., paracrine neurotrophic support and cellular replacement) of stem cell-based interventions. Accordingly, this systematic review and meta-analysis evaluated the therapeutic efficacy and safety of stem cell transplantation in experimental glaucoma models, with a focus on functional outcomes (IOP modulation), structural preservation (RGC survival, and nerve fiber layer integrity), and neuroprotective efficacy.MethodsA systematic literature retrieval from multiple online databases (e.g., PubMed, Web of Science, Embase, Cochrane Library, Scopus, CNKI, WFSD, VIP, and CBM) was conducted through 3 January 2025, to identify relevant animal experimental studies. …”
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942
Selective Plasticity of Hippocampal Sub‐Regions in the Amnestic Mild Cognitive Impairment After Acupuncture
Published 2025-08-01“…Conclusion: These results suggested that acupuncture could selectively induce structural plasticity in hippocampal subregions associated with cognitive effects in patients with aMCI, which provided potential biomarkers—particularly the right subiculum body—for effective and timely interventions for aMCI. …”
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943
Exploring Proactive Career Behavior Questionnaire Psychometrics Properties: An Adaptation to Spanish Distance Undergraduate Students
Published 2025-07-01“…To that end, the questionnaire is administered to 934 undergraduates. The factorial structure, validity and reliability of the questionnaire are analyzed, as well as the invariance of the scale as a function of gender. …”
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944
Academic and non-academic life stressors and perceived levels of stress in Brazilian undergraduate health professions students
Published 2025-08-01“…Methods This was an exploratory cross-sectional study with a mixed-methods convergent design, using a structured questionnaire with two open-ended questions focused on difficulties, and a validated scale for perceived stress. …”
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945
The use of stem cells and organoids for modeling host-microbe interactions in low-biomass tissues
Published 2025-08-01“…Together, these in vitro models realistically recapitulate structural and functional elements of the in vivo organ, allowing for studies of cellular, molecular, and genetic features that underpin various diseases that are difficult to observe in low-biomass tissues. …”
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946
Impact of surgical and non-surgical weight loss on echocardiographic and strain parameters in Asian patients
Published 2024-10-01“…However non-surgical versus SWL and the subsequent impact on myocardial function in overweight Asian subjects has not been evaluated. 66 patients underwent a 16-week lifestyle intervention (LSI) programme consisting of dietary interventions and exercise prescription. …”
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947
Farming system typology construction for the adoption of new technologies in north-west India
Published 2025-03-01“…By examining socio-economic factors and enterprise contributions, it identifies farm diversity to enhance technology adoption, improve incomes and recommend targeted policy interventions to the farmers. Using multivariate statistical techniques, structural and functional farm characteristics were analysed to construct specific farm typologies. …”
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948
Muscular robusticity and strength in the lower extremities in elite handball players
Published 2024-11-01“…The exploration and understanding of asymmetric structural and functional adaptations can help athletes and trainers in planning the training and training interventions to reduce the risk of injuries.…”
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949
Hand-Related Activities of Daily Living Challenges Among Individuals With Diabetic Peripheral Neuropathy: A Scoping Review
Published 2025-06-01“…The findings were categorised using relevant ICF codes linked to hand function issues. The analysis identified four major themes: (1) the impact of DPN on daily activities and participation; (2) sensory impairments affecting hand function; (3) muscle weakness and functional limitations; and (4) unaddressed areas, such as structural changes, driving, assisting others, and preparing meals. …”
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950
The corneoscleral shell of the eye: potentials of assessing biomechanical parameters in normal and pathological conditions
Published 2016-07-01“…Reduced CH in primary open-angle glaucoma occurs in parallel with the development of pathological structural changes of the optic disc, and deterioration of visual fields, which is an evidence of a specific character and sensitivity of this parameter. …”
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951
Symptom network between problematic smartphone use and poor sleep quality in adolescents with depression
Published 2025-05-01“…Abstract Background This study established a network structure between problematic smartphone use (PSU) and poor sleep quality (PSQ) to explore their symptomatic relationship in adolescents with depression. …”
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952
Unveiling the multifaceted role of the FLNC gene: implications for cancer diagnosis and prognosis
Published 2025-07-01“…Abstract Background The Filamin C (FLNC) gene, pivotal for cellular structure and function, holds significance in cancer biology. …”
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953
Cross-sectional associations between physical activity and sedentary time with cardiovascular health in children from the ALSPAC study using compositional data analysis
Published 2025-04-01“…Abstract This study adopted a compositional framework to cross-sectionally examine the associations between physical activity (PA) and sedentary time (ST) with vascular structure and function and clustered cardiovascular disease (CVD) risk factors in 4277 children (2,226 girls), aged 10.6±0.2 years. …”
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954
The link between stigmatization, mental health, disability, and quality of life
Published 2025-10-01“…Mental health disabilities, including conditions such as depression, anxiety, and schizophrenia, significantly impact individuals' daily functioning and overall well-being. Stigmatization, in its public, self, and structural forms, exacerbates these conditions, leading to social exclusion, reduced self-esteem, and limited access to essential resources. …”
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955
Unveiling the role of NAD glycohydrolase CD38 in aging and age-related diseases: insights from bibliometric analysis and comprehensive review
Published 2025-06-01“…BackgroundCD38, a glycoprotein with a single transmembrane structure, is extensively found in erythrocytes, immune cells, and endothelial cells. …”
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956
Understanding Pathways from Cognitive Biases to the Risk of Psychosis: A Network Analysis Approach
Published 2025-06-01“…Depressive symptom nodes serve as critical mediators between subjective cognitive problems and PLEs, underscoring their pivotal function in driving the development of PLEs among adolescents with cognitive biases. …”
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957
Changes of intestinal microbiome and its relationship with painful diabetic neuropathy in rats
Published 2025-05-01“…Sequencing analysis revealed significant differences in gut microbiota composition between PDN and control rats, with altered Bacillota/Bacteroidota ratios and increased Lactobacillus abundance. Functional annotation analysis, based on the KEGG, EggNOG, and CAZy databases, indicated significant enrichment of metabolic pathways related to carbohydrate and amino acid metabolism, energy metabolism, and cell structure biogenesis in PDN rats. …”
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958
Reconfiguring Realities: On the Intra-active Liminality of Bridges
Published 2025-07-01“…Analyses of Kafka’s short story The Bridge and multimedia interventions by Svetlana Volic posit the bridge as a performative space that transcends its original utilitarian function to emerge as a dynamic platform for posthumanist inquiry. …”
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959
Sociological Analysis of the Phenomenon of Honor Killing with the Social Interpretation Approach
Published 2024-06-01“…The research was conducted in West Azerbaijan Province and the data were collected through semi-structured, in-depth interviews. For the data analysis, a coding and data organization approach based on the CHARMS framework was utilized. …”
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960