Pharmacological and therapeutic effects of natural products on liver regeneration-a comprehensive research by Chang Tian, Yuhan Wang, Ran Wang, Linxin Pan, Tao Xu

“…Abstract Liver regeneration (LR) refers to the physiological process by which hepatocytes undergo cellular proliferation to restore the structure and function of the liver following significant hepatocyte loss due to injury or partial hepatectomy (PH). …”
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Cerebellar microglia: On the edge between neuroinflammation and neuroregulation by Marina S. Dukhinova, Jingwen Guo, Enwei Shen, Wanting Liu, Wanqi Huang, Ying Shen, Luxi Wang

“…These immune cells communicate with intrinsic and systemic factors and contribute to the structural and functional compartmentalization of the cerebellum. …”
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Mitochondrial dysfunction in the regulation of aging and aging-related diseases by Xianhong Zhang, Yue Gao, Siyu zhang, Yiqi Wang, Xinke Pei, Yufei Chen, Jinhui Zhang, Yichen Zhang, Yitian Du, Shauilin Hao, Yujiong Wang, Ting Ni

“…In this review, we first outline the basic structure of mitochondria and their essential biological functions in cells. …”
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The critical role of Toxoplasma gondii GRA1 in nutrient salvage by Bolin Fan, Biyun Qin, Mingjun Li, Yuchao Zhu, Fuqiang Fan, Hao Xu, Lilan Xue, Yukun Chen, Ming Pan, Bang Shen

“…These findings reveal the functional mode of GRA1 in T. gondii and highlight its potential as a target for developing new interventions against toxoplasmosis.…”
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Small-molecule inhibitors of the CD40–CD40L costimulatory interaction are effective in pancreatic islet transplantation and prevention of type 1 diabetes models by Sung-Ting Chuang, Oscar Alcazar, Brandon Watts, Midhat H. Abdulreda, Midhat H. Abdulreda, Midhat H. Abdulreda, Midhat H. Abdulreda, Peter Buchwald, Peter Buchwald

“…SMI-treated mice maintained the structural integrity and function of their islet allografts with concomitant reduction in immune cell infiltration as evidenced by direct longitudinal imaging in situ. …”
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Molecular mechanism on autophagy associated cardiovascular dysfunction in Drosophila melanogaster by Wei Zhang, Rong Zhou, Xinjuan Lei, Mofei Wang, Qinchun Duan, Yuanlin Miao, Tingting Zhang, Xinjie Li, Zhang Zutong, Liyang Wang, Odell D. Jones, Mengmeng Xu, Joseph Bryant, Jianjie Ma, Yingli Liu, Xuehong Xu

“…The loss of key autophagy-associated proteins, including the transmembrane protein Atg9 and its partners Atg2 or Atg18, along with DmSestrin, leads to cardiac hypertrophy and structural abnormalities in Drosophila, resembling the age-dependent deterioration of cardiac function. …”
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Proinflammatory Cytokines Trigger the Onset of Retinal Abnormalities and Metabolic Dysregulation in a Hyperglycemic Mouse Model by Gaganashree Shivashankar, Julie C. Lim, Monica L. Acosta

“…To further understand and validate the metabolic biomarkers of DR, we investigated the effect of intravitreal proinflammatory cytokines on the retinal structure, function, and metabolism in an in vivo hyperglycemic mouse model. …”
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Impact of Exercise on Physiological, Biochemical, and Analytical Parameters in Patients with Heart Failure with Reduced Ejection Fraction by Francisco Epelde

“…Exercise, once avoided in HFrEF patients due to safety concerns, is now recognized as an important therapeutic intervention. Structured exercise improves various physiological, biochemical, and analytical parameters, including cardiac output, endothelial function, skeletal muscle performance, and autonomic regulation. …”
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The Effect of Physical Activity on Alzheimer’s Disease - Systematic Review by Julia Lachowska, Karolina Senior, Jerzy Smandek, Maja Mielczarek, Paulina Sroczyńska, Jan Sroczyński

“…Evidence suggests that regular physical activity enhances cognitive function, reduces neuroinflammation, improves brain structure, and supports neuroplasticity. …”
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Sepsis beyond bundles: contextualising paediatric care in resource-limited settings through situational analysis by John Adabie Appiah, Leah Ratner, Sheila Agyeiwaa Owusu, Ahmet Uluer, Gustav Nettey, Allysa Warling, Charles Martyn-Dickens, Emma Otchere, R. Elaine Cagnina, Maame Fremah Kotoh- Mortty, Eugene Martey

“…Our findings underscore the importance of a participatory approach to guideline adaptation and resource distribution, incorporating local expertise and addressing structural inequities to improve paediatric sepsis outcomes in Ghana. …”
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Compensation of acetabular defects in primary and revision hip arthroplasty by Maria Yu. Udintseva, Elena A. Volokitina, Denis A. Kolotigin, Sergey M. Kutepov

“…Trabecular metal structures feachuring high porosity and adhesion to bone and the elastic modulus close to bone tissue provide conditions for optimal primary and secondary fixation of the component. …”

Cardiac Remodeling and Arrhythmic Burden in Pre-Transplant Cirrhotic Patients: Pathophysiological Mechanisms and Management Strategies by Charilila-Loukia Ververeli, Yannis Dimitroglou, Stergios Soulaidopoulos, Evangelos Cholongitas, Constantina Aggeli, Konstantinos Tsioufis, Dimitris Tousoulis

“…Structural changes, such as increased left ventricular mass, myocardial fibrosis, and ion channel dysfunction, further impair cardiac function. …”
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The Causal Relationship Between Asthma and Hippocampal Volume: A Study Based on Bidirectional Mendelian Randomization Analysis by Dandan Han, Shaohua Zhao

“…While observational studies suggest that asthma may affect hippocampal structure and function through mechanisms such as chronic inflammation and hypoxia, its causal relationship remains unclear. …”
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Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1 by Qinyu Zhu, Madeleine F. Yaggi, Nikolaus Jork, Henning J. Jessen, Melinda M. Diver

“…Here, cryo-electron microscopy structures of dimeric XPR1 and functional characterization delineate the substrate translocation pathway and how InsP8 initiates Pi transport. …”
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Relational coordination and team‐based care: Change initiative overload and other challenges in a learning health system by Lauren Hajjar, Olawale Olaleye, Julius Yang, Susan McGirr, Erin E. Sullivan

“…This study aims to (1) understand how relational interventions including shared huddles and cross‐role shadowing opportunities, impact team dynamics and functioning and (2) describe the challenges and opportunities associated with implementing relational interventions at an Academic Medical Center in a large metropolitan city in the United States. …”
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Investigating the neural correlates of the left thalamus in women with fibromyalgia: A Granger causality and voxel-based morphometry approach by Elijah Agoalikum, Hongzhou Wu, Benjamin Klugah-Brown, Michael Maes

“…Our findings underscore the necessity for a multi-faceted understanding of fibromyalgia that integrates neuroimaging, psychological assessments, and their implications for future therapeutic interventions. Further research is warranted to explore the longitudinal effects of treatment on structural and functional brain changes in fibromyalgia.…”
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Effects of exercise with music in frail older adults: a systematic review and meta-analysis by NamHee Kim, Gwang Suk Kim, Min Kyung Park, Layoung Kim, Jae Jun Lee, Seungbum Yang

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Corporate Real Estate alignment by Monique Arkesteijn

“…However, using PAS as add-on in these models creates methodical difficulties. The structure of these models is often not congruent with the PAS structure. …”
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Psychometric properties of the Chinese version of scales of knowledge, attitude, and practice of self-care for patients with arteriovenous fistula: a translation and verification s... by Chuang Li, Chuang Li, Youbei Lin, Jiaxin Cheng, Danfeng Xu, Danfeng Xu, Lan Zhang

“…Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted to assess the structural validity of the scale. Reliability was evaluated by calculating Cronbach’s alpha, split-half reliability, and McDonald’s Omega (Ω) to determine the internal consistency and stability of the scale.ResultsExploratory factor analysis (EFA) revealed that the translated scale has a three-factor structure, with eigenvalues greater than 1 for all factors and a total variance explanation rate of 63.099%. …”
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Validation of the de Morton Mobility Index for measuring mobility related activities in Hungarian institutionalized older adults by Zsigmond Gyombolai, Alexandra Zimonyi-Bakó, Anna Zsófia Kubik, Brigitta Arndt, Izabella Jónásné Sztruhár, Richárdné Mayer, András Simon, Gyöngyvér Molnár, Éva Kovács

“…Maintaining institutionalized older people’s functional capacity and delaying its decline requires effective interventions. …”
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