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861
Advancements in lung regeneration: from bench to bedside
Published 2025-02-01“…From stem cell and cell-based therapies to the utilization of biological and synthetic materials, as well as the strategic deployment of growth factors, a diverse array of strategies is being explored to rejuvenate lung function. By critical analysis of in vitro, preclinical, and clinical studies, this review aims to provide a comprehensive overview of the emerging technology of lung regeneration research, shedding light on promising avenues for future therapeutic interventions.…”
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862
Enduring Neurobiological Consequences of Early-Life Stress: Insights from Rodent Behavioral Paradigms
Published 2024-09-01“…These stressors can induce long-lasting changes in brain structure and function, impacting areas involved in emotion regulation, cognition, and stress response. …”
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863
Classification Based Treatment of Greater Trochanteric Pain Syndrome (GTPS) with Integration of the Movement System
Published 2022-04-01“…GTPS presents clinicians with a similar diagnostic challenge as non-specific low back pain with special tests being unable to identify the specific pathoanatomical structure involved and do little to guide the clinician in prescription of treatment interventions. …”
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864
Lomentospora prolificans synthesizes several types of melanin
Published 2025-04-01“…Like many fungi, L. prolificans produces melanin, but little is known about its structure and composition. In the current study, we characterized L. prolificans-associated melanin using chemical, biological, biophysical, and structural techniques while also assessing the impact of inhibitors of distinct melanization pathways. …”
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865
Mesoscale connectivity of the human hippocampus and fimbria revealed by ex vivo diffusion MRI
Published 2025-04-01“…Elucidating the detailed structural connectivity of the hippocampus is crucial to develop better diagnostic markers of neurological and psychiatric conditions, as well as to devise novel surgical interventions.…”
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866
Perceived social support on objective measured sedentary behavior of stroke patients: the mediating role of exercise self-efficacy
Published 2024-09-01“…IntroductionAs stroke patients may have impaired motor function, there may have increased sedentary behavior. …”
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867
Stem-Cell Niches in Health and Disease: Microenvironmental Determinants of Regeneration and Pathology
Published 2025-06-01“…Stem-cell behavior is governed not solely by intrinsic genetic programs but by highly specialized microenvironments—or niches—that integrate structural, biochemical, and mechanical cues to regulate quiescence, self-renewal, and differentiation. …”
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868
Molecular Dynamics of Apolipoprotein Genotypes APOE4 and SNARE Family Proteins and Their Impact on Alzheimer’s Disease
Published 2025-02-01“…This work highlights the perturbations in synaptic function mediated by APOE4, which may offer novel insights into the molecular underpinnings of AD. …”
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869
Social support and adolescent mental health in Kenya: a parallel mediation analysis of perceived control and gratitude
Published 2025-08-01“…The data were analyzed using structural equation modeling, controlling for age and gender.ResultsSocial support was directly associated with lower levels of depression (β = −023) and anxiety (β = −023). …”
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870
The importance of good adherence to methotrexate in the treatment of rheumatoid arthritis
Published 2025-01-01“…Methotrexate affects the function of almost all cell types involved in inflammation (neutrophils, monocytes, Tand B-cells, endothelial cells, and fibroblast-like synovium). …”
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871
A serial mediation model of physical exercise and loneliness: the role of frailty and depression
Published 2025-05-01“…Physical exercise has been widely recognized as an effective intervention to improve both the physical and mental health of older adults. …”
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872
Alzheimer’s disease pathogenesis: standing at the crossroad of lipid metabolism and immune response
Published 2025-06-01“…Lipid metabolism plays a critical role in maintaining cell membrane structure and function, regulating the production and clearance of Aβ, and supplying energy to the brain. …”
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873
Diabetic pregnancy: A literature review of maternal and neonatal adverse outcomes
Published 2025-04-01“…Pregnant patients with diabetes also have an increased risk of pre-eclampsia, likely due to complications related to abnormal structure and function of the placenta. In addition, cardiovascular complications are more common and may present antepartum, intrapartum, or postpartum. …”
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874
A review of the 661W cell line as a tool to facilitate treatment development for retinal diseases
Published 2025-04-01“…Abstract Retinal diseases encompass a diverse group of disorders that affect the structure and function of the retina, leading to visual impairment and, in some cases, irreversible vision loss. …”
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875
Principles of diet therapy for sarcopenic obesity: A review
Published 2025-01-01“…In elderly patients with SO, a reduction in body weight impacts not only the muscle mass but also muscle function. A promising approach to diet therapy for this type of obesity is qualitative modification of the diet structure used for weight loss. …”
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876
Comprehensive evaluation of clinical, echocardiographic, and CMR findings in dilated cardiomyopathy
Published 2025-01-01“…Accurate diagnosis and risk stratification are critical for optimal management, with advanced imaging playing a key role in assessing myocardial structure and function. Materials and Methods: This cross-sectional study included 75 patients diagnosed with DCM at a tertiary care center between July 2022 and July 2024. …”
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877
Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection.
Published 2024-11-01“…Conversely, genes and pathways associated with epithelial barrier function and structure were downregulated in the context of HIV. …”
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878
Contributions of mechanical loading and hormonal changes to eccentric hypertrophy during volume overload: A Bayesian analysis using logic-based network models.
Published 2025-04-01“…We believe this represents a promising approach to using the known structure of an intracellular signaling network to integrate information from multiple studies into quantitative predictions of the range of expected responses to potential interventions in the complex setting of cardiac hypertrophy driven by a combination of hormonal and mechanical factors.…”
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879
Bivariate Copula Model on Fitting Correlated Time-to-Event Outcomes: Age at First Sex and Age at First Marriage Among Youth in Tanzania
Published 2025-01-01“…This approach can inform targeted interventions to improve youth health outcomes.…”
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880
Combined exercise and Hawthorn protect against learning impairments and hippocampal damage from trimethyltin neurotoxicity in rat
Published 2025-07-01“…The superiority of the endurance and resistance training combination with hawthorn oral consumption than the unit implementation of these interventions was achieved in reducing the negative changes in the structure and the hippocampus function of neurotoxicity rats through increasing the neurotrophins levels and cholinergic modulation.…”
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