High level of soluble tumor necrosis factor receptors is associated with lower residual diuresis volume in patients on hemodialysis: An exploratory study. by Gabriele Teixeira Gonçalves, Luciana Martins de Mello Santos, Pedro Henrique Scheidt Figueiredo, Jaqueline de Paula Chaves Freitas, Jousielle Márcia Santos, Joyce Noelly Vitor Santos, Fidelis Antônio da Silva Junior, Frederico Lopes Alves, Vanessa Gomes Brandão, Emílio Henrique Barroso Maciel, Maria Cecília S M Prates, Borja Sañudo, Redha Taiar, Mario Bernardo-Filho, Danúbia da Cunha de Sá-Caputo, Vanessa Pereira Lima, Henrique Silveira, Victor Lacerda Gripp, Vanessa Amaral Mendonça, Ana Cristina Rodrigues Lacerda

“…Chronic Kidney Disease (CKD) is characterized by any persistent alteration or abnormality in kidney structure or function lasting over ninety days [1]. …”
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Portugal’s Wattle and Daub Constructive Legacy by Kátia Soares, Isabel Torres, Ana Velosa

“…The commitment to technical and scientific innovation for appropriate interventions in buildings with wattle and daub walls requires a comprehensive and authentic approach to pre-existing structures. …”
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What is the pathophysiology of inflammation-induced cortical injury in the perinatal brain? by Sharmony B. Kelly, Alistair J. Gunn, Rodney W. Hunt, Robert Galinsky

“…These inflammation-induced disturbances to neuronal structure and function are likely to underpin subsequent disturbances to cortical development and connectivity in fetuses and/or newborns exposed to infection/inflammation during the perinatal period, leading, in the long term, to impaired neurodevelopment. …”
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The Application of Diaphragm Ultrasound in Chronic Obstructive Pulmonary Disease: A Narrative Review by Heng Mu, Qunxia Zhang

“…This article aims to review the structural measurement and functional evaluation methods through the use of diaphragmatic ultrasound and relevant research on its application in clinical practice for COPD patients. …”
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Ultrastructural mitral valve abnormalities in infective endocarditis by R. A. Mukhamadiyarov, A. G. Kutikhin

“…We examined 9 mitral valves extracted during surgical interventions due to structural malfunction in patients with infective endocarditis (IE). …”
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Left ventricular flow dynamics by cardiac imaging techniques in heart failure patients: state of the art by Donato Mele, Lorenzo Serio, Riccardo Beccari, Antonella Cecchetto, Stefano Nistri, Gianni Pedrizzetti

“…Abstract Background The evaluation of left ventricular (LV) flow dynamics is a novel approach to assessing LV function that goes beyond traditional metrics. This approach has been applied to patients with heart failure (HF), providing valuable insights that are discussed in this review, with the aim of enhancing our understanding of LV function in the context of the HF syndrome. …”
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Diet-Induced Proteomic and Metabolomic Signatures in Chronic Kidney Disease: A Precision Nutrition Approach by Sandra Cabała, Agnieszka Herosimczyk

“…Additionally, several studies explore specific metabolites found in biological fluids and renal tissue in response to protein-rich foods, assessing their potential roles in a progressive loss of kidney function. Emerging evidence also suggests that dietary interventions targeting the gut microbiota may help alleviate inflammation, oxidative stress, and toxin accumulation in chronic kidney disease. …”
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Therapeutic prospects and potential mechanisms of Prdx6: as a novel target in musculoskeletal disorders by Hong Sun, Chao Xu, Chao Xu, Zhilin Xiong, Zhilin Xiong, Miao Liu, Xu Ning, Yong Zhuang

“…This study aimed to summarize the structure, regulatory mechanism, and potential function of Prdx6. …”
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The Relevance and Potential Role of Orbital Fat in Inflammatory Orbital Diseases: Implications for Diagnosis and Treatment by Prince Dadson, Peter Ngum, Luis Eduardo Juarez-Orozco, Michael Ntodie, Piotr Loba

“…Abstract The orbit is an important structure within the skull that houses the eye, optic nerve, and extraocular muscles. …”
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A modern view on the mechanisms of diabetic cardiomyopathy development and the its modification options by A. G. Sorokina, Ya. A. Orlova

“…The article is an analytical review of clinical studies  of structural  and  functional cardiac changes in patients with diabetes. …”
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Neuroimaging and Emotional Development in the Pediatric Population: Understanding the Link Between the Brain, Emotions, and Behavior by Giuseppe Marano, Maria Benedetta Anesini, Miriam Milintenda, Mariateresa Acanfora, Claudia Calderoni, Francesca Bardi, Francesco Maria Lisci, Caterina Brisi, Gianandrea Traversi, Osvaldo Mazza, Roberto Pola, Gabriele Sani, Eleonora Gaetani, Marianna Mazza

“…This narrative scoping review synthesizes current pediatric neuroimaging evidence, filling a gap in the literature by integrating structural, functional, and emerging modalities, to provide clear translational pathways for clinical and behavioral observations. …”
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Short-chain polyphosphates induce tau fibrillation and neurotoxicity in human iPSC-derived retinal neurons by Lorenzo Barolo, Lorenza Mautone, Ylenia Gigante, Silvia Ghirga, Francesco Mura, Maria Vittoria Farina, Stefano Tacconi, Luciana Dini, Giancarlo Ruocco, Alberto Boffi, Edoardo Milanetti, Silvia Di Angelantonio, Paola Baiocco

“…Abstract The onset of Alzheimer’s Disease and Frontotemporal Dementia is closely associated with the aggregation of tau, a multifunctional protein essential for neuronal stability and function. Given the role of tau aggregation in neurodegeneration, understanding the mechanisms behind its fibril formation is crucial for developing therapeutic interventions to halt or reverse disease progression. …”
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A high fat, high sugar diet exacerbates persistent post-surgical pain and modifies the brain-microbiota-gut axis in adolescent rats by Sabrina Salberg, Matthew Macowan, Angela Doshen, Glenn R. Yamakawa, Marissa Sgro, Benjamin Marsland, Luke A. Henderson, Richelle Mychasiuk

“…Therefore, we investigated how daily consumption of a HFHS diet modified the development of PPSP, brain structure and function, and the microbiome. In addition, we identified significant correlations between the microbiome and brain in animals with PPSP. …”
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Research progress in predicting the conversion from mild cognitive impairment to Alzheimer’s disease via multimodal MRI and artificial intelligence by Min Ai, Yu Liu, Dan Liu, Chengxi Yan, Xia Wang, Xun Chen

“…Multimodal magnetic resonance imaging (MRI) techniques (including structural MRI, functional MRI, and cerebral perfusion MRI) can yield information on the morphology, structure, and function of the brain from multiple dimensions, providing a key basis for revealing the pathophysiological mechanisms during the conversion from MCI to AD. …”
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Determination of the molecular basis for a limited dimorphism, N417K, in the Plasmodium vivax Duffy-binding protein. by Amy M McHenry, Samantha J Barnes, Francis B Ntumngia, Christopher L King, John H Adams

“…Successful vaccine development necessitates a deeper understanding of the role of these polymorphisms in both parasite function and evasion of host immunity. A 3D structure of the homologous P. knowlesi DBP predicts that most variant residues are surface-exposed, including N417K, which is a dimorphic residue change that has previously been shown to be part of a linked haplotype that alters DBP sensitivity to inhibitory antibody. …”
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Types of combined neurovascular injuries of the extremities by I. V. Pertsov

“…Combined injuries of neurovascular structures are associated with poor results of limb function restoration, often lead to disability and lower quality of life. …”
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Linker Histones Maintain Genome Stability and Drive the Process of Cellular Ageing by George Miloshev, Penyo Ivanov, Bela Vasileva, Milena Georgieva

“…Here, we discuss emerging evidence that suggests linker histones have functions that extend beyond their traditional roles in chromatin architecture, highlighting their critical involvement in genome stability, cellular ageing, and cancer development, thereby establishing them as promising targets for therapeutic interventions.…”
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Cystatin F-a key player in central nervous system disease by Yi-Ting Wang, Qiang Li, Jun-Chao Liu, Chen Chen, He-Xuan Ding, Xu Zha, Ke Zhang

“…It has several unique characteristic structures that determine some of its specific functions. …”
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Virtual and Augmented Reality for Chronic Musculoskeletal Rehabilitation: A Systematic Review and Exploratory Meta-Analysis by Theodora Plavoukou, Pantelis Staktopoulos, Georgios Papagiannis, Dimitrios Stasinopoulos, George Georgoudis

“…<b>Objective:</b> To systematically evaluate the effectiveness of VR, AR, and exergaming interventions in improving pain, function, balance, and psychological outcomes among adults with CMDs. …”
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A park-based group mobility program for older adults with difficulty walking outdoors: a qualitative process evaluation of the Getting Older Adults Outdoors (GO-OUT) randomized con... by Kristina M. Kokorelias, Jacquie Ripat, Ruth Barclay, C. Allyson Jones, Nancy E. Mayo, Theresa Grant, Stephanie Scodras, Kyla Alsbury-Nealy, Charlotte Ryder-Burbidge, Nancy M. Salbach

“…Methods A qualitative descriptive study involving semi-structured interviews conducted at 6-months post-baseline was conducted. …”
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