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821
Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review
Published 2025-06-01“…ABSTRACT Background Aging significantly affects the structural and functional integrity of the blood–brain barrier (BBB), increasing the susceptibility of the central nervous system (CNS) to both primary and metastatic cancers. …”
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822
Rethinking Osteoarthritis Management: Synergistic Effects of Chronoexercise, Circadian Rhythm, and Chondroprotective Agents
Published 2025-03-01“…This time-sensitive, comprehensive approach aims to slow OA progression, reduce structural damage, and delay invasive procedures, particularly in weight-bearing joints such as the knee and hip. …”
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823
Application of infrared-beam laser therapy in the postoperative period in patients with nodular toxic goiter
Published 2022-11-01“…Thyroidectomy prevailed in the structure of surgeries in the main group (20 (57.1 %) cases). …”
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824
Conformational Analysis of Tyrosyl-Lysyl-Threonine Tripeptide Using MM, MD and QM Methods and Its Hyperpolarizability Study
Published 2022-08-01“…Peptides are important structures that offer important opportunities for therapeutic interventions in various diseases. …”
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825
Single-cell RNA sequencing: new insights for pulmonary endothelial cells
Published 2025-06-01“…This technology provides critical insights into the phenotypic diversity and distinct molecular signatures of PECs, underscoring their substantial heterogeneity in structure, function and gene expression, which is contingent upon their spatial localization within the lung microenvironment. …”
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826
Respiratory health and chronic disease risks in residents of agricultural areas in Chiang Mai, Northern Thailand.
Published 2025-01-01“…A cross-sectional study involving 145 participants was conducted in San Pa Tong District from October to December 2023, utilizing structured questionnaires and spirometry tests to evaluate lung function and chronic health disease risk. …”
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827
Music Therapy in Depression: Exploring Mechanisms and Efficacy in Rat Models
Published 2025-03-01“…Second, the effects of music on the physiological and biochemical indexes, as well as the neural structure and function of depressed rats, were discussed. …”
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828
Attenuation of primate aging via systemic infusion of senescence-resistant mesenchymal progenitor cells
Published 2025-06-01“…SRC treatment improved cognitive performance, preserved brain structure, protected bone integrity, and rejuvenated immune function. …”
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829
Optimizing learning outcomes in physical education: A comprehensive systematic review of hybrid pedagogical models integrated with the Sport Education Model.
Published 2024-01-01“…SEM, serving as the foundational structure, provides a stable framework for the hybrid, termed the "SEM + 1 model," yielding positive effects on enhancing students' learning outcomes.…”
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830
Genicular Arteries Embolization for Patients with Osteoarthritis, Their Selection, and Follow-Up Based on MRI Findings
Published 2025-05-01“…This article explores GAE’s mechanism, patient-selection criteria, and effectiveness in pain reduction and functional improvement. Studies suggest that GAE has the potential to significantly improve pain and function in mild to moderate OA, with sustained benefits. …”
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831
The Chongqing Adolescent Twin Study: An Integrative Multimodal Brain Imaging and Non-imaging Dataset
Published 2025-07-01“…This dataset includes multimodal MRI scans (structural, resting-state functional, and diffusion MRI) alongside extensive questionnaires on cognitive abilities, emotional and social behaviors, familial and parenting dynamics, sleep wellness, stress, anxiety, and depression. …”
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832
Physiotherapy management of Parkinson’s disease in a tertiary hospital in Nigeria: a case report
Published 2025-04-01“…This case report details the physiotherapy management of a 72-year-old male patient with stage 3 PD, highlighting a structured 14-week physiotherapy program that targeted balance, coordination, and cognitive function. …”
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833
Postbiotics as Mitochondrial Modulators in Inflammatory Bowel Disease: Mechanistic Insights and Therapeutic Potential
Published 2025-07-01“…They improve mitochondrial function and boost ATP production. Moreover, postbiotics reduce oxidative damage by regulating antioxidant defenses. …”
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834
The characteristics of anhedonia in depression: a review from a clinically oriented perspective
Published 2025-03-01“…At the biological level, MDD patients with anhedonia seem to present higher levels of inflammatory factors, abnormal metabolic function and hypermetabolism of BDNF. In brain imaging studies, there are some structural and/ or functional changes in multiple brain regions of subcortical and cortical areas, as well as the limbic system in MDD patients with anhedonia. …”
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835
Membraneless organelles in health and disease: exploring the molecular basis, physiological roles and pathological implications
Published 2024-11-01“…Abstract Once considered unconventional cellular structures, membraneless organelles (MLOs), cellular substructures involved in biological processes or pathways under physiological conditions, have emerged as central players in cellular dynamics and function. …”
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836
Nasal deformities in cleft lip and palate: an update for dental professionals
Published 2025-01-01“…The quality of life and daily activities of patients may be greatly impacted by these defects, which can impose numerous functional limitations. The complex nasal structure in these cases makes treatment difficult, and a range of protocols has been developed to address both appearance and function. …”
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837
Applications of augmented reality in cardiology till 2024: a comprehensive review of innovations and clinical impacts
Published 2025-07-01“…AugR has revolutionized cardiology by enhancing the understanding of cardiac structure and function. This review highlights its applications in diagnosis, surgical planning, cardiac procedures, training, rehabilitation, and the future impact of AugR-related technology.MethodsThis review compiles original research and review articles on AugR in cardiology from PubMed till 2024.ResultsAdvancements in visualization and image processing techniques facilitate the development of AugR tools using holographic displays, enhancing diagnostic accuracy and pre-surgical planning. …”
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838
Nature-based solutions (Nbs) for flood mitigation: Recent UK case studies
Published 2024-01-01“…Understanding the hydrological functioning of the Nbs interventions is important in determining their effectiveness in reducing flood risks. …”
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839
Funding the future: safeguarding pediatric health equity through CMS and CHIP
Published 2025-07-01“…Interventions reviewed include Functional Family Therapy (FFT) for adjudicated youth, a hospital-led asthma management initiative in Ohio, community-based care engagement strategies in disorganized Chicago neighborhoods, and a national policy analysis of CHIP's effectiveness. …”
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840
Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances
Published 2025-03-01“…Thus, we aim to elucidate the role of ageing in neurodegenerative diseases from the perspective of a complex system, in which the brain is the core and peripheral organs and tissues form a holistic network to support brain functions. During ageing, the progressive deterioration of the structure and function of the entire body hampers its active and adaptive responses to various stimuli, thereby rendering individuals more vulnerable to neurodegenerative diseases. …”
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