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Sexual dimorphism in the response to antidepressant therapy: Biological basis and clinical implications declaration of competing interests author contributions
Published 2024-01-01“…Neurobiological studies highlight gender-specific differences in brain structure and function, as well as in neurotransmitter systems, which may impact treatment efficacy and response variability. …”
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802
Boosting Psychotherapy With Noninvasive Brain Stimulation: The Whys and Wherefores of Modulating Neural Plasticity to Promote Therapeutic Change
Published 2024-01-01“…The phenomenon of neural plasticity pertains to the intrinsic capacity of neurons to undergo structural and functional reconfiguration through learning and experiential interaction with the environment. …”
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803
Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review
Published 2025-06-01“…This review systematically summarizes the structural and functional properties of DP, explores their mechanism of action and experimental evidence in retinal neovascularization, and analyzes their potential as a new therapeutic strategy for retinal diseases. …”
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804
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805
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806
Spatial Complex Morphological Evolution and Influencing Factors for Mountain and Seaside Resort Tourism Destinations
Published 2020-01-01“…The study contributes to complex morphological evolution from the perspectives of external structure expansion and internal function reconstruction, revealing the spatial characteristics and explaining the influencing factors. …”
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807
A Framework for Healthcare Provision to Children with Intellectual Disability
Published 2013-02-01“…The objectives of this study were to evaluate the structure and functioning of ‘Buds’ schools, to identify the healthcare needs of the students, and to conceptualise a framework for healthcare provision.…”
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808
Bupropion for the treatment of apathy in Huntington's disease: A multicenter, randomised, double-blind, placebo-controlled, prospective crossover trial.
Published 2017-01-01“…In addition, we investigated the effect of bupropion on brain structure as well as brain responses and functional connectivity during reward processing in a gambling task using magnetic resonance imaging (MRI).…”
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809
Harnessing exercise to combat chronic diseases: the role of Drp1-Mediated mitochondrial fission
Published 2025-02-01“…This, in turn, enhances mitochondrial function and cellular metabolism. This review synthesizes the current understanding of Drp1 structure and activation mechanisms, and analyzes the effects of exercise interventions on Drp1-mediated mitochondrial fission in different disease models to improve common chronic conditions. …”
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810
Effect of endothelial responses on sepsis-associated organ dysfunction
Published 2024-12-01“…However, excessive or prolonged endothelial activation can lead to impaired microcirculation, tissue hypoperfusion, and organ dysfunction. Given the structural and functional heterogeneity of endothelial cells in different organs, there are potential differences in endothelial responses by organ type, and the risk of organ damage may vary accordingly. …”
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811
Post‐Translational Modifications in Cilia and Ciliopathies
Published 2025-08-01“…In addition, accumulating evidence has shown that PTMs are essential for modulating ciliary structure and function, and that dysregulation of these modifications leads to the development of ciliopathies. …”
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812
The relationship between childhood trauma and obsession is mediated by emotional schema and reappraisal
Published 2025-04-01“…Method: 681 Iranian students responded to CTQ-SF, ERQ, LESS-II, and OCI-R. The structural equation model method has been utilized to investigate the mediation of variables. …”
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813
Molecular Biomarkers for Timely and Personalized Prediction of Maternal-Fetal Health Risk
Published 2025-02-01“…Placental structural function is vital for fetal growth and development, and disruptions can lead to serious pregnancy complications like preeclampsia. …”
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814
Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review.
Published 2013-01-01“…Our meta-analysis of the two largest knee studies using risedronate 15 mg showed odds ratios favouring placebo interventions for the Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain (1.73), WOMAC function (2.03), and WOMAC stiffness (1.82). …”
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815
Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies
Published 2025-04-01Get full text
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816
A high-definition spatiotemporal transcriptomic atlas of mammalian kidney development
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817
The cys-loop ligand-gated ion channel gene superfamily of the Colorado potato beetle, Leptinotarsa decemlineata
Published 2025-07-01“…Alternative splicing and RNA editing conserved in insect species were also identified in expected subunits, potentially contributing to structural and functional diversity of the receptor. …”
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818
The impact of pituitary adenomas on cognitive performance: a systematic review
Published 2025-04-01“…Twelve studies focused on structural brain changes as assessed by magnetic resonance imaging, with half documenting volumetric reductions in gray matter. …”
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819
Safety and Efficacy of Combination Therapy with Anti-Vascular Endothelial Growth Factor and Laser for Retinopathy of Prematurity: A Systematic Review and Meta-Analysis
Published 2025-01-01“…Combination therapy of anti-VEGF and laser photocoagulation was compared with other interventions. The pooled analysis of favorable structural outcomes did not show a statistically significant difference between combination therapy with anti-VEGFs and laser therapy compared to the interventions in the control groups (P=0.25). …”
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820
Stretchable wireless optoelectronic synergistic patches for effective wound healing
Published 2024-10-01“…Mechanistically, optoelectronic synergistic intervention enhances the secretion of vascular endothelial marker proteins and growth factors, and stabilizes mitochondrial function during oxidative stress. …”
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