Functional and structural brain remodeling in patients with degenerative cervical myelopathy following cervical decompression surgery by Bingyong Xie, Haoyu Ni, Jiyuan Yao, Zhibin Xu, Sicheng Bian, Haoxiang Wang, Kun Zhu, Xianyong Wu, Peiwen Song, Yuanyuan Wu, Yongqiang Yu, Fulong Dong

“…Methods In this prospective cohort study, we conducted an analysis of data from 54 patients with DCM both before and after surgery, as well as 57 healthy controls (HC), using functional MRI in combination with high-resolution structural MRI. …”
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A structured lifestyle intervention to reduce cardiometabolic risk factors in individuals with obsessive–compulsive disorder: feasibility trial by Anna Holmberg, Matthias Lidin, Dante Lenninger, Sofia Asplund, Catharina Lavebratt, Christian Rück, Lina Martinsson, David Mataix-Cols, Lorena Fernández de la Cruz

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Effectiveness of robot therapy on body function and structure in people with limited upper limb function: A systematic review and meta-analysis. by Fernanda Márcia Rodrigues Martins Ferreira, Maria Emília Abreu Chaves, Vinícius Cunha Oliveira, Adriana Maria Valladão Novais Van Petten, Claysson Bruno Santos Vimieiro

“…This systematic review aimed to investigate the effectiveness of RT on the body function and structure of people with upper limb impairments (PROSPERO registration: CRD42017054982). …”
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The effects of restraint stress and orthodontic tooth movements on the intestinal epithelial structure and metabolic function in rats. by Ye Cheng, Yue Li, Ziqing Fan, Nannan Wang, Min Wang, Yanfen Li, Chao Liu, Huang Li, Fuhua Yan

“…This study aimed to investigate the effects of restraint stress and orthodontic treatment on the intestinal epithelial structure, barrier function, flora, and metabolism in rats. …”
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The regulatory effects of bioactive polysaccharides on intestinal function and bile acids: chemical structures, bioactivities, and mechanisms by Anqi Wang, Anqi Wang, Wugui Xiong, Jing Li, Yingfan Hu, Liang Zou, Ying Liu, Ying Liu

“…Polysaccharides usually interact directly or indirectly with the gut and gut microbiota to participate in the regulation process of reabsorption, metabolism, and excretion of bile acids in humans, thereby exerting their role in the intervention of human diseases. In this review, we comprehensively reviewed the effects of bioactive polysaccharides on the regulation of intestinal function and bile acids. …”
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Effects of SNX9 on the structure and function of primary cilia in autosomal dominant polycystic kidney disease by Shen Ai-wen, Hu Wan-qian, Lin Lu, Yu Sheng-qiang

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The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes. by Ursula Straschil, Arthur M Talman, David J P Ferguson, Karen A Bunting, Zhengyao Xu, Elizabeth Bailes, Robert E Sinden, Anthony A Holder, Elizabeth F Smith, Juliet C Coates, Rita Tewari

“…Using homology modelling, bioinformatics analysis and complementation studies in Chlamydomonas, we show that some regions of the PF16 protein are highly conserved across all eukaryotes, whereas other regions may have species-specific functions. PF16 is the first ARM-repeat protein characterised in the malaria parasite genus Plasmodium and this study opens up a novel model for analysis of Plasmodium flagellar biology that may provide unique insights into an ancient organelle and suggest novel intervention strategies to control the malaria parasite.…”
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Matrix Remodeling Associated Genes (MXRAs): structural diversity, functional significance, and therapeutic potential in tumor microenvironments by Chao Zeng, Xiao Lv, Feng Wang, Yaomin Huang, Yanxian Ren, Hengwei Zhang

“…Notably, each MXRA member exhibits unique structural characteristics and functional properties, contributing to a diverse array of regulatory effects within the tumor context. …”
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The effects of structured coordinative exercise protocol on physical fitness, motor competence and inhibitory control in preschool children by Ali Mert Şendil, Umut Canlı, Bodor Bin sheeha, Nouf H. Alkhamees, Alexios Batrakoulis, Sameer Badri Al-Mhanna

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Assessing executive functioning in higher education: development and structural validation of a new self-report scale by Samuel Zamora-Lugo, Vicenta Reynoso-Alcántara, Javier Sanchez-Lopez, Samana Vergara-Lope, Elizabeth Ocampo-Gómez, María Luisa García-Gomar, Cynthia Torres-González, Gloria Nélida Avecilla-Ramírez, Cintli Carolina Carbajal-Valenzuela, Melissa Calderón, Almitra Vázquez-Moreno, Rubén Flores-González, Carlos César Contreras-Ibáñez, Félix Ángel Montero-Domínguez, Aurora de Jesús Mejía-Castillo, Alicia Abundis-Gutierrez, José Elías Sánchez-Cid, María Iliana Osorio-Guzmán, Gregorio García-Aguilar, Agustín Jaime Negrete-Cortes, Naghelli Cisneros Báez, Luz María Martell Ruiz, Paulina Campos Romero, Rossana de Fátima Cuevas-Ferrera

“…However, few assessment tools provide psychometrically validated and contextually appropriate measures for university populations.MethodsThis study presents the development and structural validation of the Executive Functions Scale in Higher Education (EFEES), a self-report instrument designed to evaluate university students’ self-perceived executive functioning. …”
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Structured, multifactorial randomised controlled intervention to investigate physical activity levels, body composition and diet in obese and overweight adolescents by Prateek Srivastav, Vaishali K, Vinod H Bhat, Suzanne Broadbent

“…This study will investigate the effects of a structured multifactorial (school-based and family-based) intervention on adolescent obesity, compared with a single or no intervention.Methods and analysis A pragmatic, clustered randomised controlled trial with 12 weeks of interventions and 3-month, 6-month and 12-month follow-ups will be conducted at multiple participating schools in Karnataka, India. …”
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Structural and functional roles of conserved residues of human papillomavirus (HPV) E2 protein and biological consequences by Sean Fletcher, Esther E. Biswas-Fiss, Subhasis B. Biswas

“…The HPV E2 protein is a central regulator of viral replication and oncogene expression, making it a critical determinant of HPV-associated malignancies. While its core functions are conserved, variations within the E2 protein are thought to contribute to the differential oncogenic potential among HPV types, though the structural basis for this remains incompletely understood. …”
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Automated Detection and Biomarker Identification Associated with the Structural and Functional Progression of Glaucoma on Longitudinal Color Fundus Images by Iyad Majid, Zubin Mishra, Ziyuan Chris Wang, Vikas Chopra, Dale Heuer, Zhihong Jewel Hu

“…Moreover, while visual function is the main concern for glaucoma patients, and the ability to infer future visual outcome from imaging will benefit patients by early intervention, there is currently no available tool for this. …”
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The role of structural and functional parameters in designing pathology-specific tDCS protocols for primary progressive aphasia by Sagarika Bhattacharjee, P. T. Sivakumar, Ganesan Venkatasubramanian, Kenichi Oishi, Kyrana Tsapkini, S. H. Annabel Chen, Brenda Rapp, John E. Desmond, T. N. Sathyaprabha, Kaviraja Udupa, Rajan Kashyap

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Research Progress in Bioactive Compounds in Medicine Food Homologous Plants for Intervention in Diabetes by ZHOU Yixia, QIN Luqi, DIAO Rao, ZHENG Jiahuan, LIU Jiameng, FAN Bei

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The mediating role of daily living ability and sleep in depression and cognitive function based on a structural equation model by Liu Huijun, Zhang Xiange, Yang Ming, Sun Jiayi, Peng Juanjuan, Xu Wangquan, Song Yueli, Fang Guixia

“…They should also pay attention to the impact of their sleep quality and daily activity ability, so as to better maintain cognitive function.…”
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Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood‐Gas Exchange by Kai P. Barbian, Teresa Lemainque, Ina Grunden, Roman Iwa, Bettina Wiegmann, John Linkhorst, Matthias Wessling, Jan Heyer, Ulrich Steinseifer, Michael Neidlin, Sebastian V. Jansen

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Bioinformatics analysis to investigate the potential relationship between mitochondrial structure and function-related genes and the immune microenvironment in atherosclerosis by Hanning Yang, Yue Sun, Shumin Li, Yueyue Tang, Yuxue Wang, Yunyan Li, Yongping Lu

“…ObjectiveThis study aims to elucidate the interactions between genes associated with mitochondrial structure and function and the immune microenvironment in atherosclerosis.MethodsDifferentially expressed mitochondria-related genes (DE-MRGs) were identified through the analysis of two gene expression datasets, GSE100927 and GSE159677, in conjunction with a list of mitochondria-related genes sourced from the MitoCarta3.0 database. …”
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An integrative analysis of functional consequences of PKD2 missense variants on RNA and protein structures: a computational approach by Chandra Devi, Prashant Ranjan, Parimal Das

“…Abstract Background The PKD2, encoding polycystin-2 (PC2) protein, is second major genetic determinant of autosomal dominant polycystic kidney disease (ADPKD) after PKD1. However, the structural and functional consequences of genetic variants in PKD2 remain poorly understood. …”
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In-depth insight into tumor-infiltrating stromal cells linked to tertiary lymphoid structures and their prospective function in cancer immunotherapy by Maedeh Radandish, Niloofar Mashhadi, Amir Hossein Aghayan, Motahareh Taghizadeh, Sara Salehianfard, Sheida Yahyazadeh, Omid Vakili, Somayeh Igder

“…However, the dualistic role of tertiary lymphoid structures (TLSs), which serve as critical immune hubs within the TME, remains incompletely characterized, particularly with respect to their context-dependent capacity to either inhibit or facilitate tumor development. …”
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