Understanding the lived experience research priorities for improving health-related quality of life in people living with HIV with cognitive impairment by Kate Alford, Jaime H. Vera, John Hammond, Stephanie Daley

“…Results Five people living with HIV with CI, recruited through third sector agencies [Male 80%; median age 59 (range 56–78); White British 60%; homosexual 60%], and three healthcare and third sector participants (66% third sector professionals from two local HIV charities; 33% HIV-specific clinical psychologist) took part in two focus groups and ranked interventions targeting improvement in physical function, social connectedness, cognition and perceived control over cognitive health as priority areas. …”
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Effect and Mechanism of Action of Pushing Method on Rats with Skeletal Muscle Overuse Injury based on Wnt/β-catenin Signaling Pathway by DUAN Miaomiao, HUANG Bo, RUAN Lei, MU Pangpang, CHEN Yiming, PENG Liang

“…Catenin protein expression levels.Results(1) Comparison of motor function：compared with the blank group, the time of passing through the balance beam and the number of times of sliding paw were significantly increased in the model group and intervention group after intervention, and the difference was statistically significant (<italic>P</italic>&lt;0.05); compared with the model group, the time of passing through the paw and the number of times of sliding paw were significantly decreased in the intervention group after intervention, and the difference was statistically significant (<italic>P</italic>&lt;0.05). (2) Gastrocnemius muscle histopathological changes：the model group can be seen in the gastrocnemius muscle a large number of myocytes can be seen within the cracks, myogenic fibers fracture; compared with the model group, the degree of damage to the gastrocnemius muscle tissues in the intervention group to reduce the degree of damage, can be seen in the form of myofibers is regular, neatly arranged. (3) Ultrastructural changes in gastrocnemius muscle tissue：local myogenic fiber bundles were broken and dissolved, and a small amount of Z-line structure was dissolved and blurred; compared with the model group, the gastrocnemius muscle cells in the intervention group were slightly edematous, and the structure of the myogenic fiber bundles was clear; part of the myogenic fiber bundles were broken, and the structure of the Z-lines was clear and more neatly arranged. (4) Gastrocnemius muscle tissue MyoD, MyoG and Pax7 mRNA transcript levels：compared with the blank group, MyoD, MyoG and Pax7 mRNA transcript levels were significantly higher in both the model group and the intervention group (<italic>P</italic>&lt;0.05); compared with the model group, MyoD, MyoG and Pax7 mRNA transcript levels were significantly higher in the intervention group (<italic>P</italic>&lt;0.05). (5) Gastrocnemius muscle tissue MyoD, MyoG and Pax7 protein expression level：compared with the blank group, MyoD, MyoG and Pax7 protein expression water were significantly higher in both the model group and the intervention group (<italic>P</italic>&lt;0.05); compared with the model group, MyoD, MyoG and Pax7 protein expression level was significantly higher in the intervention group (<italic>P</italic>&lt;0.05). (6) Wnt3a, Axin2 and β-catenin protein expression levels in gastrocnemius muscle tissues：compared with the blank group, Wnt3a, Axin2 and β-catenin protein expression levels were significantly higher in both the model group and the intervention group (<italic>P</italic>&lt;0.05); compared with the model group, Wnt3a, Axin2 and β-catenin protein expression levels were significantly higher in the intervention group (<italic>P</italic>&lt;0.05).ConclusionPushing method can improve the gastrocnemius muscle injury and motor function in rats with overuse injury model, and its mechanism may be related to the activation of Wnt/β-catenin signaling pathway.…”
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Leveraging flexible pipette-based tool changes to transform liquid handling systems into dual-function sample preparation and imaging platforms by Mohammad Nazeri, Jeffrey Watchorn, Sheldon Mei, Alex Zhang, Christine Allen, Frank Gu

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Tai Chi as a mind-body exercise modulates endothelial function in coronary artery disease: A randomized clinical trial by Yameng Li, Cuihan Li, Jiansheng Wen, Meize Cui, Qiuyang Wei, Mingyu Liu, Zaihao Chen, Hui Fang, Linli Liu, Jiahao Fu, Jianwei Zhang, Shaojun Lyu

“…However, the effects of TC on endothelial function in CAD patients compared to aerobic exercise (AE) remain understudied. …”
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Effect of Acupuncture on the Expression of Heme Oxygenase 1 and Inflammatory Factors in Rats with Intracerebral Hemorrhage by CHEN Qiuxin, KONG Ying, YU Tingting, ZHANG Yu, LIU Peng, ZHANG Xin

“…Modified Neurological Severity Score （mNSS） was used to evaluate the neurological function of rats after intracerebral hemorrhage on 1 d, 3 d and 7 d. …”
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“I always wondered if my baby is able to feel my love for them” -  Development and pilot testing of two behavioural feedback strategies designed to improve maternal self-efficacy [... by Rebecca M Pearson, Shane A Norris, Alessandra Prioreschi, Antonia Smith, Deborah M James, Kirsten L Rennie

“…When embedded in a supportive intervention, these feedback modalities have the potential to improve mother’s self-efficacy through increasing feelings of competence and reflexive functioning.…”
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Enhancing implementation of information and communication technologies for post-discharge care among hospitalized older adult patients: development of a multifaceted implementation... by Dorothy Yingxuan Wang, Eliza Lai-Yi Wong, Annie Wai-Ling Cheung, Zoe Pui-Yee Tam, Kam-Shing Tang, Eng-Kiong Yeoh

“…Additionally, the Implementation Research Logic Model is utilized to synthesize, organize, and visually present the collected data. Results This structured process identified and selected five intervention functions, 11 behavior change techniques, and four policy categories. …”
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What do we know about nursing practice in relation to functional ability limitations, frailty and models of care among older people in home- and facility-based care: a scoping revi... by Ida Røed Flyum, Edith Roth Gjevjon, Anna Josse Eklund, Gunilla Borglin

“…Abstract Background Nursing practice in long-term care, must support the delivery of safe and evidence-based care, especially for older people with functional ability limitations and frailty, with the competency, knowledge and structured working modes such practice requires. …”
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Effect of Combination of Yoga, Naturopathy Medicine, and Herbs on Renal Functions and Quality of Life in Patients with Chronic Kidney Disease: A Pilot Study by Y. Deepa, A. Vijay, L. Nivethitha, Edmin Christa, N. Manavalan, A. Mooventhan

“…Background: Chronic kidney disease (CKD) is distinguished by abnormality in kidney structure or function that persists for over 3 months. …”
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The Relationship between Trait Impulsivity and Everyday Executive Functions among Patients with Type 2 Diabetes Mellitus: The Mediating Effect of Negative Emotions by Na Liu, Chun-Ni Heng, Yi Cui, Ling Li, Yan-Xue Guo, Qin Liu, Bao-Hua Cao, Di Wu, Yin-Ling Zhang

“…The participants completed the Sociodemographic Questionnaire, Mini-Mental State Examination (MMSE), Barratt Impulsiveness Scale-Brief (BIS-Brief), Depression Anxiety and Stress Scales with 21 items (DASS-21), and Behavior Rating Inventory of Executive Function-Adult (BRIEF-A) version. A structural equation modeling was used to verify the mediating effect of negative emotions on the relationship between trait impulsivity and EFs. …”
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Explaining personality functioning through sociocultural attitudes toward appearance, body appreciation and social media usage among female adolescents in Pakistan by L. Khan, S. Tariq, N. Ishfaq

“…</strong> The findings suggest the need for interventions that address the negative impact of sociocultural pressure regarding appearance on body appreciation and personality functioning among female adolescents. …”
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Clostridium butyricum enhances cognitive function in APP/PS1 mice by modulating neuropathology and regulating acetic acid levels in the gut microbiota by Ye Shiqing, Lu Xinjie, Zhu Xiaotong, Chen Jiayan, Lu Jiahai, Chen Xiaodong, Lou Yongliang, Li Xiang

“…While not altering the overall gut flora structure, CBM588 increased acetate-producing bacteria and decreased pro-inflammatory genera, reducing lipopolysaccharide levels. …”
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Psychometric properties of the Arabic version of the McMaster family assessment device–general functioning subscale (FAD-GF) among a sample of Lebanese adults by Melyssa Assaf, Rabih Hallit, Diana Malaeb, Fouad Sakr, Mariam Dabbous, Feten Fekih-Romdhane, Sahar Obeid, Souheil Hallit

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SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol. by Maik Gollasch, Yulia Komleva, Dmitry Tsvetkov, Felix Morof, Mladen V Tzvetkov, Till Ittermann, Marcus Vollmer, Uta Zahn-Tesch, Holger Kock, Franziska Schuster, Neeltje van den Berg, Henry Völzke, Stefan Engeli, Lieven Kennes, Marwan Mannaa

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Mindful Nonreactivity, Anxiety, Depression, and Perceived Stress as Mediators of the Mindfulness Virtual Community Intervention—Pathways to Enhance Mental Health in University Stud... by Meysam Pirbaglou, Christo El Morr, Farah Ahmad, Paul Ritvo

“…MethodsMediation analysis, using structural equation modeling, was used to assess direct and indirect relationships between study group (ie, intervention or wait list control) and outcomes. …”
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Social Participation of Frail Older People with Functional Limitations Ageing Alone in Place in Italy, and Its Impact on Loneliness: An Urban–Rural Comparison by Maria Gabriella Melchiorre, Marco Socci, Giovanni Lamura, Sabrina Quattrini

“…The results also indicate some different nuances regarding urban and rural sites. (4) Conclusions: Despite the fact that this exploratory study did not have a representative sample of the target population, and that only general considerations can be drawn from results, these findings can offer some insights to policymakers who aim to develop adequate interventions supporting the social participation of older people with functional limitations ageing in place alone. …”
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Exploring the relationship between intrinsic capacity and social participation in healthy ageing: Evidence from Singapore by Grace Cheong, William Tov, Robin Wai Munn Choo, Micah Tan, Lay Khoon Lau, Wee Shiong Lim, Yew Yoong Ding, Paulin Tay Straughan

“…This study emphasizes the need for healthcare interventions aimed towards the promotion of healthy ageing to adopt a holistic approach that enhance IC across its five domains, ensuring both social and physical participation and functional independence of older adults.…”
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Beyond clinical risk: tackling loneliness through a population health lens by Ananda Zeas-Sigüenza, Ananda Zeas-Sigüenza, Pablo Ruisoto, Pablo Ruisoto, Pablo Ruisoto, Kami Koldewyn, Ferran Muntané, Ferran Muntané, Joan Benach, Joan Benach

“…Specifically, we propose a loneliness spectrum model and a systemic intervention framework that targets structural determinants, positioning loneliness prevention as a fundamental public health strategy through nature-based and community-driven interventions.…”
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ArfGAP3 Protects Mitochondrial Function and Promotes Autophagy Through Rab5a‐Mediated Signals in Ageing Skeletal Muscle by Mao Chen, Xiaoyu Huang, Bingshu Li, Ya Xiao, Liying Chen, Fangyi Zhu, Shasha Hong, Jianming Tang, Suting Li, Jie Min, Wenyi Jin, Yubiao Zhang, Lian Yang, Yang Li, Shufei Zhang, Li Hong

“…Methods Mouse models of natural ageing and D‐gal (D‐galactose)–induced ageing were subject to analyse the structure, function and pathological alterations of the PFM and the expression of ArfGAP3. …”
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Comparative effects of square-stepping and strengthening exercises on cognitive and balance functions in chronic obstructive pulmonary disease: a randomized clinical trial by Alp Özel, Eylem Tütün Yümin, Suat Konuk

“…Background Cognitive impairment and balance dysfunction are common in individuals with chronic obstructive pulmonary disease (COPD), yet targeted interventions remain limited. Square-stepping exercise (SSE), a structured multitasking intervention involving progressive, multi-directional step patterns, combines cognitive and motor challenges. …”
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