The efficacy and safety of ketorolac for postoperative pain management in lumbar spine surgery: a meta-analysis of randomized controlled trials by Jianbin Guan, Ningning Feng, Kaitan Yang, Haimiti Abudouaini, Peng Liu

“…Data were extracted and analyzed using open-source meta-analysis software OpenMeta-Analyst, focusing on outcomes such as VAS pain scores, postoperative morphine requirements (PMR), length of hospital stay (LOS), and adverse effects, such as nausea, vomiting, pruritus, and constipation. …”
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Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada. by Kevin Ten Haaf, Martin C Tammemägi, Susan J Bondy, Carlijn M van der Aalst, Sumei Gu, S Elizabeth McGregor, Garth Nicholas, Harry J de Koning, Lawrence F Paszat

“…Therefore, the objective of this study was to estimate the cost-effectiveness of lung cancer screening in a population-based setting in Ontario, Canada, and evaluate the effects of screening eligibility criteria.<h4>Methods and findings</h4>This study used microsimulation modeling informed by various data sources, including the Ontario Health Insurance Plan (OHIP), Ontario Cancer Registry, smoking behavior surveys, and the NLST. …”
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Efficacy and safety of oxaliplatin-based chemotherapy as first-line treatment in elderly patients with metastatic colorectal cancer: a meta-analysis by Shaoqing Fan, Zeming Zhao, Haiqian Wang, Handong Wang, Wenbo Niu

“…Subgroup analyses explored heterogeneity sources, including chemotherapy combinations (e.g., bevacizumab, panitumumab).ResultsSeven RCTs (1,839 patients) met inclusion criteria. …”
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Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review by K. Taneille Johnson, Ammar AlZadjali, Dawoud Al Nasseri, Jessie Cunningham, Kazuhiro Shoya, Cecil D. Hahn, Cecil D. Hahn, Cecil D. Hahn, John Basmaji, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon

“…ObjectiveWe aim to determine the optimal dosing of midazolam continuous intravenous infusions for the treatment of pediatric refractory status epilepticus (RSE).Data sourcesWe searched Medline ALL, Embase, Embase Classic, Cochrane CENTRAL, and Web of Science in March 2023 and again in February 2024.Study selectionRandomized and non-randomized studies involving pediatric patients who received continuous midazolam for the treatment of RSE were eligible. …”
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An eHealth Intervention to Improve Quality of Life, Socioemotional, and Health-Related Measures Among Older Adults With Multiple Chronic Conditions: Randomized Controlled Trial by David H Gustafson Sr, Marie-Louise Mares, Darcie Johnston, Olivia J Vjorn, John J Curtin, Gina Landucci, Klaren Pe-Romashko, David H Gustafson Jr, Dhavan V Shah

“…Tested moderators were sex, scheduled health care use, and number of chronic conditions. Data sources were surveys at baseline and 6 and 12 months comprising validated scales, and continuously collected ElderTree usage. …”
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Synergistic effect of compost and moringa leaf extract biostimulants on the remediation of gold mine tailings using chrysopogon zizanioides by Nkanyiso Mlalazi, Luke Chimuka, Mulala Danny Simatele

“…Phytoremediation is a cost-effective and environmentally friendly method for restoring degraded land. However, optimizing phytoremediation conditions and using locally sourced materials can further improve the sustainability of this approach. …”
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Key frame extraction algorithm for surveillance videos using an evolutionary approach by Manjusha Rajan, Latha Parameswaran

“…Evolutionary algorithms offer a powerful solution for achieving optimal KFE. This proposed method leverages an interactive GA with a well-designed Fitness Function and elitism-based survivor selection to enhance performance. …”
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Image navigator–based, automated coronary magnetic resonance angiography for the detection of coronary artery stenosis by Gregory Wood, Reza Hajhosseiny, Alexandra Uglebjerg Pedersen, Simon Littlewood, Tina Juul Hansen, Radhouene Neji, Karl P. Kunze, Jens Wetzl, Bjarne Linde Nørgaard, Jesper Møller Jensen, Michael Maeng, Per Lav Madsen, Niels Vejlstrup, Claudia Prieto, René M. Botnar, Won Yong Kim

“…Additionally, the study incorporates the utilization of standardized postprocessing with sliding-thin-slab multiplanar reformatting, in combination with evaluation of the source images, to optimize the visualization of coronary artery stenosis. …”
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A customized ensemble machine learning approach: predicting students’ exam performance by Rasel Ahmed, Nafiz Fahad, Md Saef Ullah Miah, Kah Ong Michael Goh, Mufti Mahmud, M. Mostafizur Rahman

“…Using a dataset of 500 students sourced from Kaggle, we introduce a novel customized ensemble machine learning model, combining Random Forest (RF) and AdaBoost classifiers with a custom-weighted soft voting method (weights of 0.2 for RF and 0.8 for AdaBoost). …”
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Outcomes of Living Kidney Donors Following Donor Nephrectomy in Aotearoa New Zealand by Lai Wan Chan, Georgina L. Irish, Tze L. Goh, Basil Alnasrallah, Christopher E. Davies, Matthew P. Sypek, Philip A. Clayton, Michael G. Collins

“…Introduction: Living donor kidney transplantation is the optimal treatment for people with kidney failure (KF). …”
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Improving nutritional quality and aflatoxin detoxification of peanut meal by co-fermentation with Weizmannia coagulans, Bacillus subtilis, and supplemented enzymes by Youwei Chen, Hao Huang, Dan Li, Limei Zou, Wendi Yu, Weiwei Dong, Xiang Yu, Yanli Feng, Jun Liu, Shumiao Zhao, Yunxiang Liang, Yuanliang Hu, Nan Peng

“…Microbial fermentation is one of the most effective methods to reduce anti-nutritional factors and enhance the nutritional value of peanut meal. …”
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Assessment of bimodal laser photodynamic therapy at wavelenths of 410 nm and 653 nm for oral precancerous lesions: An in vitro and in vivo study by Shuiting Fu, Ting Zhu, Lu Chen, Guoyu Zhou, Jian Sun

“…There is a pressing demand for innovations that can enhance the effectiveness of PDT and minimize its side effects in addressing oral precancerous lesions. Materials and methods: This study employed m-THPC as a photosensitizer and developed a novel light source with dual wavelengths of 410 nm/653 nm tailored to excite the photosensitizer. …”
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Meeting people where they are: Crowdsourcing goal-specific personalized wellness practices. by Johanna E Hidalgo, Julia Kim, Jordan Llorin, Kathryn Stanton, Josh Cherian, Laura Bloomfield, Mikaela Fudolig, Matthew Price, Jennifer Ha, Natalie Noble, Christopher M Danforth, Peter Sheridan Dodds, Jason Fanning, Ryan S McGinnis, Ellen W McGinnis

“…In this study, we crowd-sourced helpful, flexible, and engaging wellness practices to identify a list of those commonly used for improving sleep, productivity, and physical, emotional, and social wellness from participants who felt they had been successful in these dimensions.…”
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Potential evaluation and development utilization technology of geothermal resources in the Jining Coalfield by Qipeng SHI, Jianguo FAN, Fengfeng SHI, Xuesen WANG, Huiming ZHENG, Jia MENG, Shuailiang SONG

“…Under the guidance of China’s “carbon peaking and carbon neutrality” goals, efforts are underway to optimize and adjust the national energy structure. …”
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Program Report—Transplant Manitoba Adult Kidney Program Cutting Costs, Not Corners: Value of Quality Improvement Initiatives by Christie Rampersad, Aaron Trachtenberg, James Shaw, Nancy Dodd, Krista Maxwell, Martin Karpinski, Chris Wiebe, Peter Nickerson, Julie Ho

“…Methods: To quantify the potential cost savings, we employed a 3-pronged approach. …”
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Geopolitics and Muslim Countries: Navigating Challenges and Opportunities in Contemporary International Political Dynamics by Yahdi Qolbi, M. Ibnu Ashari. R, Diana, Imaro Sidqi

“…The study employs a qualitative analysis approach with a literature review method. Data is sourced from secondary materials such as academic journals, books, policy reports, and articles relevant to the geopolitical issues of Muslim countries. …”
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Effects of corn variety in whole-plant corn silage on dry matter intake, average daily gain and gastrointestinal tract bacteria and metabolites in Hu lambs by Jianxin Jiao, Jianxin Jiao, Jianxin Jiao, Shumin Ma, Shumin Ma, Shumin Ma, Ting Jiao, Ting Jiao, Ting Jiao, Shangli Shi, Shangli Shi, Shangli Shi, Yongquan Gao, Yongquan Gao, Yongquan Gao, Xia Zhang, Xia Zhang, Xia Zhang, Shengguo Zhao, A. Allan Degen

“…Understanding how different WPCS varieties influence gastrointestinal microbiota and metabolic profiles is essential for optimizing feed efficiency and animal health.MethodsThis study examined the effects of three corn varieties (2 introduced - Tunyu 168: TY; Yu silage 23: YQZ, and 1 local Longsheng 1: LS) in WPCS on gastrointestinal bacteria and metabolites in lambs. …”
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High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform by Sascha D. Braun, Sascha D. Braun, Martin Reinicke, Martin Reinicke, Celia Diezel, Celia Diezel, Elke Müller, Elke Müller, Katrin Frankenfeld, Thomas Schumacher, Hugo Arends, Stefan Monecke, Stefan Monecke, Ralf Ehricht, Ralf Ehricht, Ralf Ehricht

“…However, the development of such assays is often hindered by the time-consuming process of identifying high-affinity antibody pairs.MethodsTo accelerate this process, we evaluated a protein microarray platform as a high-throughput screening tool to identify optimal monoclonal antibody (mAb) pairs targeting the most clinically relevant carbapenemases. …”
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The Effect of Different Levels of Vermicompost and Chemical Fertilizer on some Quantitative and Qualitative Traits of Three Maize (Zea mays L.) Cultivars by Mohammad Akbari, Gholamreza Heidari, Shiva Khalesro, Mohammad Majidi

“…IntroductionMaize is a primary source of food for humans, livestock and industrial purposes. …”
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Mesenchymal stem cells derived from hPSC via neural crest attenuate chemotherapy-induced premature ovarian insufficiency by ameliorating apoptosis and oxidative stress in granulosa... by Xinran Li, Jinrong Liao, Youhong Zheng, Wei Cai, Jie Chen, Yu Liang, Yuanmei Chen, Xiaoxuan Li, Jiamao Luo, Jiaxin Xie, Manping Zhou, Lilin Hang, Xiujuan Sun, Xin Yue, Xuefeng Wang, Yifeng Wang, Huiyan Wang

“…Conclusions Our findings propose a modified hPSC-NCC-MSC differentiation protocol, offering an inexhaustible and stable source for regenerative therapies. Furthermore, we provide the first experimental evidence that hPSC-NCC-MSC have therapeutic potential comparable to UC-MSC in restoring chemotherapy-induced POI. …”
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