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Microarray Data Analysis: From Hypotheses to Conclusions Using Gene Expression Data
Published 2004-01-01“…We review several commonly used methods for the design and analysis of microarray data. To begin with, some experimental design issues are addressed. …”
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42
A Novel Ensemble Feature Selection Technique for Cancer Classification Using Logarithmic Rank Aggregation Method
Published 2024-04-01“…Recent studies have shown that ensemble feature selection (EFS) has achieved outstanding performance in microarray data classification. …”
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43
A review of independent component analysis application to microarray gene expression data
Published 2008-11-01“…Independent component analysis (ICA) methods have received growing attention as effective data-mining tools for microarray gene expression data. …”
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44
Identification of the feline humoral immune response to Bartonella henselae infection by protein microarray.
Published 2010-07-01“…Understanding the complex interactions between the host's immune system and bacterial pathogens is central to the field of infectious diseases and to the development of effective diagnostics and vaccines.<h4>Methodology</h4>We report the development of a microarray comprised of proteins expressed from 96% (1433/1493) of the predicted ORFs encoded by the genome of the zoonotic pathogen Bartonella henselae. …”
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CRISPR screens and lectin microarrays identify high mannose N-glycan regulators
Published 2024-11-01“…We used CRISPR screens to uncover the expanded network of genes controlling high mannose levels, followed by lectin microarrays to fully measure the complex effect of select regulators on glycosylation globally. …”
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A tailored lectin microarray for rapid glycan profiling of therapeutic monoclonal antibodies
Published 2024-12-01“…In this study, we introduce a custom-designed lectin microarray featuring nine distinct lectins: rPhoSL, rOTH3, RCA120, rMan2, MAL_I, rPSL1a, PHAE, rMOA, and PHAL. …”
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High reproducibility using sodium hydroxide-stripped long oligonucleotide DNA microarrays
Published 2005-01-01“…In addition, when there is limited availability of mRNA from tissue sources, RNA amplification can and is being used to produce sufficient quantities of cRNA for microarray hybridization. Taking advantage of the selective degradation of RNA under alkaline conditions, we have developed a method to “strip” glass-based oligonucleotide microarrays that use fluorescent RNA in the hybridization, while leaving the DNA oligonucleotide probes intact and usable for a second experiment. …”
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Microarray Evidences the Role of Pathologic Adipose Tissue in Insulin Resistance and Their Clinical Implications
Published 2011-01-01“…The microarray evidences of molecular basis of obesity and insulin resistance are presented here. …”
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49
Genetic Comparison and Selection of Reproductive and Growth-Related Traits in Qinchuan Cattle and Two Belgian Cattle Breeds
Published 2025-02-01“…A total of 270 Belgian cattle (91 BR and 179 BWR) and 286 Qinchuan cattle were genotyped using the Illumina Bovine SNP 50K microarray. Data analysis was conducted using PLINK and Beagle 5.1 to estimate linkage disequilibrium (LD) and effective population size (Ne). …”
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50
Etiological diagnosis of miscarriage by combining use of chromosomal microarray analysis and whole-exome sequencing
Published 2025-07-01“…Abstract Background Chromosomal microarray analysis (CMA) is being increasingly used to reveal the genetic causes of miscarriage. …”
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51
Machine learning identification of molecular targets for medulloblastoma subgroups using microarray gene fingerprint analysis
Published 2025-01-01“…The classification achieved an average accuracy of 96%, demonstrating the effectiveness of the proposed approach. Feature selection using the Kruskal–Wallis and χ2 tests revealed statistically relevant genes contributing to subgroup discrimination. …”
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Microarray analysis of virulence gene profiles in Salmonella serovars from food/food animal environment
Published 2010-09-01“…Conclusions: This hybridization array presents an accurate and cost-effective method for evaluating the disease-causing potential of Salmonella in outbreak investigations by targeting a selective set of Salmonella-associated virulence genes. …”
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53
THE VALIDATION OF THE RESULTS OF MICROARRAY STUDIES OF ASSOCIATION BETWEEN GENE POLYMORPHISMS AND THE FREQUENCY OF RADIATION EXPOSURE MARKERS
Published 2014-06-01“…The results from the selective validation research into the association between genetic polymorphisms and the frequency of cytogenetic abnormalities on a large independent sample are analyzed. …”
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Discovery of possible gene relationships through the application of self-organizing maps to DNA microarray databases.
Published 2014-01-01“…DNA microarrays and cell cycle synchronization experiments have made possible the study of the mechanisms of cell cycle regulation of Saccharomyces cerevisiae by simultaneously monitoring the expression levels of thousands of genes at specific time points. …”
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Molecular sub-classification of renal epithelial tumors using meta-analysis of gene expression microarrays.
Published 2011-01-01“…<h4>Experimental design</h4>A search of publicly available databases was performed to identify microarray datasets with multiple histologic sub-types of renal cortical neoplasms. …”
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Integrated Use of Statistical-Based Approaches and Computational Intelligence Techniques for Tumors Classification Using Microarray
Published 2015-01-01“…With the recent development of biotechnologies, cDNA microarray chips are increasingly applied in cancer research. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer
Published 2025-02-01“…Transfection efficiency was confirmed via qRT-PCR in HCT116 and SW480 colon cells, and the effects of circDOCK1 on cell proliferation, migration, and invasion were assessed.ResultsMicroarray data revealed 149 significantly differentially expressed circRNAs, including 71 upregulated and 78 downregulated circRNAs, in CRC tissues. …”
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High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform
Published 2025-08-01“…The array allowed simultaneous mapping of cross-reactivity, a key advantage over conventional ELISA workflows.DiscussionOur findings confirm that protein-based microarrays offer a robust, efficient platform for antibody pair selection, reducing reagent use while accelerating assay development. …”
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Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Current research is focused on identifying effective treatments for PTSD. Advances in bioinformatics provide opportunities to elucidate the underlying mechanisms of PTSD. …”
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Possibility of the Use of Public Microarray Database for Identifying Significant Genes Associated with Oral Squamous Cell Carcinoma
Published 2012-03-01“…This study combined two small microarray datasets from a public database and identified significant genes associated with the progress of oral squamous cell carcinoma. …”
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