Gene co-expression module study identifies key genes and pathways underpinning hypercholesterolemia-induced atherosclerosis development by Muhammad-Redha Abdullah-Zawawi, Muhammad Irfan Abdul Jalal, Siti Aishah Sulaiman, Nur Alyaa Afifah Md Shahri, Rahman Jamal, Nor Azian Abdul Murad

“…Methods The Affymetrix microarray dataset (GSE13985), which includes samples from five healthy controls and five FH patients, was obtained from the Gene Expression Omnibus (GEO) database. …”
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Identification of Key Genes and Potential Therapeutic Targets in Sepsis-Associated Acute Kidney Injury Using Transformer and Machine Learning Approaches by Zhendong Zhai, JunZhe Peng, Wenjun Zhong, Jun Tao, Yaqi Ao, Bailin Niu, Li Zhu

“…Early diagnosis and effective therapy remain difficult despite extensive investigation. …”
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Genetic testing for oral clefts: reflections based on a single Brazilian public genetics service by Tamiris Nogueira Bezerra Bueno, Társis Paiva Vieira, Vera Lúcia Gil-da-Silva-Lopes

“…They also show the need to improve public health policies for genetic evaluation, diagnostic tests, and genetic counseling for an effective NPCCPRD.…”
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The Necessity of Prenatal Diagnosis by CMA for the Women with NIPS-Positive Results by Jun Xu, Ying Xue, Jing Wang, Qin Zhou, Bin Zhang, Bin Yu, Ting Wang

“…Single nucleotide polymorphism array testing was performed on a commercial 750K microarray chip (Affymetrix CytoScan 750K Array). Results. …”
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VEGF Contributes to Mesenchymal Stem Cell-Mediated Reversion of Nor1-Dependent Hypertrophy in iPS Cell-Derived Cardiomyocytes by Denise Philipp, Michelle Holthaus, Vida Basoah, Kurt Pfannkuche, Laura Suhr, Thorsten Wahlers, Adnana Paunel-Görgülü

“…Phenylephrine (PE) was used to induce hypertrophy in murine iPS-CM, and markers of hypertrophy were identified by microarray analysis. Murine MSCs were treated with IFN-γ and IL-1β to enhance their paracrine activity, and transcriptional profiling was performed by microarray analysis. …”
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HuoXueJieDu Formula Alleviates Diabetic Retinopathy in Rats by Inhibiting SOCS3-STAT3 and TIMP1-A2M Pathways by Hongliang Wang, Wei Xing, Shijie Tang, Zhenglin Wang, Tiantian Lv, Yan Wu, Shuzhen Guo, Chun Li, Jing Han, Ruixin Zhu, Wei Wang

“…HuoXueJieDu (HXJD) formula exerts protective effects against diabetic retinopathy (DR) in rats, but its underlying mechanism remains unknown. …”
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Exploration of the shared gene signatures and comorbidity mechanisms of primary aldosteronism and atrial fibrillation by Jindong Wan, Sen Liu, Tao Luo, Yi Yang, Dan Wang, Xinquan Wang, Peng Zhou, Jixin Hou, Peijian Wang

“…These hub genes were subsequently validated via two independent external datasets: GSE60042 (PA microarray dataset) and GSE41177 (AF microarray dataset). …”
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Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts by Fulin Liu, Christine Rouault, Mickael Guesnon, Wencan Zhu, Karine Clément, Séverine A. Degrelle, Thierry Fournier

“…Here, we aimed to explore the genome-wide effects of PPARγ on EVCTs and VCTs via treatment with the PPARγ-agonist rosiglitazone. …”
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Downregulation of sorting nexin 10 is associated with overexpression of miR-30d during liver cancer progression in rats by Nancy Cervantes-Anaya, Alberto Ponciano-Gómez, Guadalupe Soledad López-Álvarez, Christian Gonzalez-Reyes, Sergio Hernández-Garcia, María Asunción Cabañas-Cortes, José Efraín Garrido-Guerrero, Saúl Villa-Treviño

“…The identification of molecules that might be molecular markers or therapeutic targets is urgently needed to improve clinical management. Based on a microarray analysis performed in our laboratory, we selected six genes—namely, ANXA2, DYNLT1, PFKP, PLA2G7, KRT19 , and SNX10 —as candidates for validation as tumor markers of liver cancer in a rat model. …”
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SPP1 mRNA Expression Is Associated with M2 Macrophage Infiltration and Poor Prognosis in Triple-Negative Breast Cancer by Yu-Chia Chen, Chia-Ching Chen, Rong-Fu Chen, Hsin-Hung Chen, Po-Ming Chen

“…Additionally, we examined SPP1 mRNA expression datasets available in the Kaplan–Meier plotter and investigated the SPP1 protein expression patterns in our own tissue microarray cohort via immunohistochemistry. (3): The results revealed that genes associated with the Toll-like receptor signaling pathway showed a significant increase in activity in TNBC tissues when compared to normal breast tissues. …”
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Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle. by Mary K McGahon, Janet M Yarham, Aideen Daly, Jasenka Guduric-Fuchs, Lyndsey J Ferguson, David A Simpson, Anthony Collins

“…The expression of known miRNAs in the heart has been studied at length by microarray and quantitative PCR but it is becoming evident that microRNA isoforms (isomiRs) are potentially physiologically important. …”
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Biomarkers and potential therapeutic targets driving progression of non-alcoholic steatohepatitis to hepatocellular carcinoma predicted through transcriptomic analysis by Hui Fan, Rong Wang, Bin Wen, Jing Xiong

“…Despite its widespread impact, effective treatments to prevent the progression of NASH remain elusive, highlighting the critical importance of innovative molecular techniques in both the diagnosis and management of this disease.MethodsSix microarray datasets available in GEO were used to perform Robust Rank Aggregation (RRA) to identify differentially expressed genes (DEGs).We identified 62 robust upregulated genes and 24 robust downregulated genes. …”
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TRIM13 prevents cardiomyocyte injury by affecting apoptosis through interacting with CD3D in myocardial infarction by Feipeng Wu, Xiandong Zheng, Qiyan Wu, Liju Hong, Lei Yue, Rui Yang, Dandan Chen, Youjun Zhou

“…We aim to develop potential and more effective therapeutic strategies for treating and preventing MI. …”
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Oncolytic virotherapy provides a potent therapy option for squamous bladder cancer by Julia Pannhausen, Julia Wirtz, Klaus Mantwill, Per-Sonne Holm, Kristina Schwamborn, Danny D. Jonigk, Jürgen E. Gschwend, Michael Rose, Nadine T. Gaisa, Roman Nawroth

“…Furthermore, immunohistochemical staining of 89 SCC on a tissue microarray confirmed strong YB-1 expression in squamous BLCA (sq-BLCA). …”
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CaGe: A Web-Based Cancer Gene Annotation System for Cancer Genomics by Young-Kyu Park, Tae-Wook Kang, Su-Jin Baek, Kwon-Il Kim, Seon-Young Kim, Doheon Lee, Yong Sung Kim

“…High-throughput genomic technologies (HGTs), including next-generation DNA sequencing (NGS), microarray, and serial analysis of gene expression (SAGE), have become effective experimental tools for cancer genomics to identify cancer-associated somatic genomic alterations and genes. …”
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Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression by Cheng Dai, Bin Shen, Shenyan Liu, Cong Li, Shuqun Yang, Jie Wang, Jie Zhang, Manqi Liu, Zhixuan Zhu, Wan Shi, Qi Zhang, Zhui Chen, Nannan Zhang

“…Immunohistochemistry (IHC) was utilized to analyze human tissue microarray samples of osteosarcoma. We then investigated the anti-tumor effect and the mechanisms of action of pharmacologic inhibition of CSF-1R activity by pimicotinib (ABSK021), a highly potent and selective small molecule inhibitor of CSF-1R, in osteosarcoma models both in vitro and in vivo. …”
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ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser by A. V. Saetchnikov, M. M. Yatskou, P. V. Nazarov, L. Vallar, V. V. Apanasovich

“…The developed software has a number of advantages over the existing software: it is free, has a simple and intuitive graphical interface, allows to analyze different types of DNA microarrays, contains a set of methods for complete data analysis and performs effec-tive gene annotation for a selected list of genes.…”
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The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A by Iwona Adwent, Beniamin Oskar Grabarek, Marta Kojs-Mrożkiewicz, Ryszard Brus, Rafał Staszkiewicz, Andrzej Plewka, Michał Stasiowski, Anita Lyssek-Boroń

“…The expression profile of mRNA related to TGFβ paths was indicated by microarray and RTqPCR analyses. The ELISA test was used to analyze changes on the proteome level. …”
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Fecal carriage of vanB antibiotic resistance gene affects adipose tissue function under vancomycin use by Lars M. M. Vliex, Giang N. Le, Marina Fassarella, Dorien Reijnders, Gijs H. Goossens, Erwin G. Zoetendal, John Penders, Ellen E. Blaak

“…Abdominal subcutaneous adipose tissue (AT) gene expression was assessed using Affymetrix microarray. Gut microbial composition was determined using the Human Intestinal Tract Chip (HITChip) microarray. …”
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RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis by S. M. Nuruzzaman Nobel, S M Masfequier Rahman Swapno, Md. Ashraful Hossain, Mejdl Safran, Sultan Alfarhood, Md. Mohsin Kabir, M. F. Mridha

“…This study primarily uses a unique dataset painstakingly selected from 20 esteemed medical institutes. The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. …”
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