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521
Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/N...
Published 2016-01-01“…Further data refinements identified groups of key markers showing group-specific expression patterns, with a substantial reprogramming event evident at the four to six week interval. Selected statistically-significant gene entities from this study and other immune and apoptotic markers were validated using qPCR, which confirmed many of the results obtained using microarray hybridisation. …”
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522
Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell...
Published 2016-01-01“…Here, we report on studies designed to uncover how tumour cells respond to sub-lethal doses of cisplatin. A microarray study revealed changes in gene expressions that occurred when A549 cells were exposed to a no-observed-effect level (NOEL) of cisplatin (e.g. the IC10). …”
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523
RTP4, a Biomarker Associated with Diagnosing Pulmonary Tuberculosis and Pan-Cancer Analysis
Published 2023-01-01“…Pulmonary tuberculosis (PTB) is a global epidemic of infectious disease; the purpose of our study was to explore new potential biomarkers for the diagnosis of pulmonary tuberculosis and to use the biomarkers for further pan-cancer analysis. Methods. Four microarray gene expression sets were downloaded from the GEO public databases and conducted for further analysis. …”
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524
Citrus flavonoids for overcoming breast cancer resistance to methotrexate: identification of potential targets of nobiletin and sinensetin
Published 2025-03-01“…Protein targets of citrus flavonoids were identified from multiple databases and were collected using Venny 2.1. Microarray data of MCF-7 and MCF-7/MTX cells were acquired from the Gene Expression Omnibus. …”
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525
Mapping autoantibody targets of full-length C-reactive protein in systemic lupus erythematosus: importance for neutrophil function and classical complement activation
Published 2025-05-01“…The levels of anti-CRP and SLE-associated antibodies were assessed, and a microarray-based linear epitope mapping was performed to detect binding sites on the full CRP monomer. …”
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526
Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma
Published 2019-03-01“…Methods We downloaded the microarray data from the Gene Expression Omnibus (GEO) database. …”
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527
Prevalence and Diversity of <i>Staphylococcus aureus</i> in Bulk Tank Milk from Community-Based Alpine Dairy Pastures in Tyrol, Austria
Published 2025-07-01“…A total of 140 isolates collected from the 94 <i>S. aureus</i>-positive community-based Alpine dairy pastures revealed 33 distinct <i>spa</i> types, with t2953 (<i>n</i> = 33), t529 (<i>n</i> = 12), t267 (<i>n</i> = 11), and t024 (<i>n</i> = 10) being the most common. Selected isolates representing the different <i>spa</i> types were characterised by DNA microarray-based genotyping, multi-locus sequence typing (MLST), and antimicrobial susceptibility testing. …”
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528
Electrochemical Strategies for MicroRNA Quantification Leveraging Amplification and Nanomaterials: A Review
Published 2025-07-01“…However, conventional detection methods, such as Northern blotting, RT-PCR, and microarrays, are limited by low sensitivity, lengthy protocols, and limited specificity. …”
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529
Potential Canonical Wnt Pathway Activation in High-Grade Astrocytomas
Published 2012-01-01“…A cytoplasmic β-catenin pool was detectable in 13/15 cultures leading to some transcriptional activity assessed by luciferase reporter gene assay in 8/13. …”
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530
Over Time Changes in the Transcriptomic Profiles of Tomato Plants with or Without <i>Mi-1</i> Gene During Their Incompatible or Compatible Interactions with the Whitefly <i>Bemisia...
Published 2025-03-01“…Motelle, incompatible interaction) was studied using the oligonucleotide microarray technique. Both interactions were studied 2 and 12 days post infestation (dpi) of plants with adult insects. …”
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531
Effects of Benzo[a]Pyrene Exposure on Lung Cancer: A Mechanistic Study of Epigenetic m6A Levels and YTHDF1
Published 2025-04-01“…TMT labeling-based proteomic analysis and clinical lung tissue microarray assays demonstrated that CDK6 and MAP3K6 were positively correlated with YTHDF1 expression. …”
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532
Genetic and functional characterization of inherited complex chromosomal rearrangements in a family with multisystem anomalies
Published 2025-01-01“…They often require karyotyping, fluorescence in situ hybridization, and chromosomal microarray analysis (CMA) for clinical diagnosis because of the limitations of each method. …”
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533
Bioinformatic analyses reveal lysosomal-associated protein transmembrane 5 as a potential therapeutic target in lipotoxicity-induced injury in diabetic kidney disease
Published 2024-12-01“…Here, we analyzed the GSE 30529 microarray datasets of human tubulointerstitial tissue samples from the Gene Expression Omnibus database (GEO). …”
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534
MicroRNA let-7f protects against H2O2-induced oxidative damage in neuroblastoma cells by targeting AKT-2
Published 2020-04-01“…Material and methods miRNA microarray analysis was performed to detect the miRNAs’ differential expression in AD patients and normal elderly volunteers. …”
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535
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis
Published 2025-02-01“…Methods TCGA public database and a tissue microarray were used to investigate the molecular characteristics of CLIP4 and its association with disease. …”
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536
Identification and validation of hub genes associated with biotic and abiotic stresses by modular gene co-expression analysis in Oryza sativa L.
Published 2025-03-01“…A total of 11, 12, 46, and 14 modules containing 85, 106, 253, and 143 hub genes were detected in drought, salinity, tungro virus, and blast. …”
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537
Expression and clinical significance of FGL1 and YAP1 in colorectal cancer
Published 2025-07-01“…<b>Methods</b> Tissue microarray technique was used to detect FGL1 and YAP1 expression in 101 colorectal cancer tissues and 79 adjacent tissues from June 2007 to April 2008. …”
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538
Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma
Published 2025-04-01“…Abstract Background Protein aggrephagy, a selected autophagy process response for degrading protein aggregates, plays a critical role in various cancers. …”
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539
Screening and identification of potential target of 1′-acetoxychavicol acetate (ACA) in acquired lapatinib-resistant breast cancer
Published 2024-12-01“…Genomic mutations, expression levels, prognostic significance, and ROC analysis were examined in selected genes. We used AutoDock Vina to conduct ACA molecular docking with potential target genes. …”
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540
HDAC1 Mediates Immunosuppression of the Tumor Microenvironment in Non-Small Cell Lung Cancer
Published 2025-03-01“…However, there are no studies on the immunological aspects of HDAC1 in non-small cell lung cancer (NSCLC).Methods: In this research, we used the Cancer Genome Atlas (TCGA) public database combined with tissue microarray (TMA) to investigate HDAC1 expression and prognosis in NSCLC. …”
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