Profiling of gastric cancer cell-surface markers to achieve tumour–normal discrimination by Henry Yang, Khek Yu Ho, Judith Toh, Michal Marek Hoppe, Teena Thakur, Kar Tong Tan, Brendan Pang, Sharmaine Ho, Rony Roy, Khay Guan Yeoh, Raghav Sundar, Anand Jeyasekharan

“…After validation with TCGA data (n=29 matched tumour and normal pairs), the following proteins were selected for mIHC analysis: CEACAM5, CEACAM6, CLDN4, CLDN7, and EpCAM. …”
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Application of family whole-exome sequencing for prenatal diagnosis—an analysis of 357 cases by Yijun Ge, Huizhen Yuan, Yao Yu, Junfang Xiao, Danping Liu, Yongbao Peng, Ying Liu, Shuhui Huang, Bicheng Yang, Yongyi Zou, Yanqiu Liu

“…Using techniques such as amniotic fluid, chorionic villus, or umbilical cord blood sampling, intact fetal cells were extracted for cell culture and subsequently analyzed using chromosomal karyotyping and chromosomal microarray techniques. 2. With fully informed consent, fetuses and their parents whose genetic etiology could not be detected by karyotyping combined with chromosomal microarray technology had their cellular DNA subjected to whole-exome sequencing of the pedigree. 3. …”
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Robust modeling of differential gene expression data using normal/independent distributions: a Bayesian approach. by Mojtaba Ganjali, Taban Baghfalaki, Damon Berridge

“…In this paper, the problem of identifying differentially expressed genes under different conditions using gene expression microarray data, in the presence of outliers, is discussed. …”
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Yield of Genetic Testing in Children with Autism Spectrum Disorder – A Single-Center Experience by Kriti Arora, Minakshi Balwani, Akash Wakchaure, Gouri R Passi

“…Yield of whole exome sequencing (WES), 12/27 (44.49%), was more than that of chromosomal microarray (CMA) 1/30 (3.3%) (P < 0.05). Fragile-X gene mutation was detected in 0/14 patients tested. …”
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Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects by Louise Kaldjob-Heinrich, Sandro Nuciforo, Steffen Lemke, Aaron Stahl, Stefan Czemmel, Sepideh Babaei, Lauriane Blukacz, Marie-Anne Meier, Yizheng Zhang, Christian M. Schürch, Irene Gonzalez-Menendez, Pascal Woelffing, Nisar P. Malek, Veit Scheble, Sven Nahnsen, Manfred Claassen, Markus Templin, Hans Bösmüller, Markus H. Heim, Daniel Dauch, Michael Bitzer

“…However, further data are required to clarify ADORA3 expression patterns in liver cancer, mechanisms of action, and the potential for combination therapies to inform patient selection for future clinical trials. Methods: Patient-derived tissue microarrays and RNA-sequencing were employed to investigate ADORA3 expression. …”
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Exploring the Functional Disorder and Corresponding Key Transcription Factors in Intraductal Papillary Mucinous Neoplasms Progression by Guiying Bai, Chenxuan Wu, Yingtang Gao, Guiming Shu

“…This study has analyzed the gene expression patterns of an IPMN microarray dataset including normal pancreatic ductal tissue (NT), intraductal papillary mucinous adenoma (IPMA), intraductal papillary mucinous carcinoma (IPMC), and invasive ductal carcinoma (IDC) samples. …”
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Pan-cancer analysis identifies CD155 as a promising target for CAR-T cell therapy by Xiaohong Liu, Yue Sun, Boxu Lin, Hao Xiong, Xinyue Lu, Binghe Tan, Chenglin Zhang, Mingyao Liu, Juliang Qin, Na Zhang, Bing Du

“…Conclusions Our study demonstrates that CD155 is selectively expressed in cancer cells while being rarely detected in normal tissues, and may serve as a promising pan-cancer target for CAR-T therapy. …”
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High-Resolution Genomic Profiling of Chromosomal Abnormalities in Human Stem Cells Using the 135 K StemArray by Aaron M. Elliott, Kristi A. Hohenstein Elliott, Anja Kammesheidt

“…Here, we describe an improved version of our StemArray, a stem-cell-focused comparative genomic hybridization (aCGH) microarray, which contains 135,000 probes and covers over 270 stem cell and cancer related genes at the exon level. …”
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Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma. by Ananya Roy, Julia Femel, Elisabeth J M Huijbers, Dorothe Spillmann, Erik Larsson, Maria Ringvall, Anna-Karin Olsson, Magnus Åbrink

“…A microarray expression analysis and functional annotation of differentially expressed genes identified several biological pathways where serglycin may be important. …”
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Integration of the transcriptome and glycome for identification of glycan cell signatures. by Sandra V Bennun, Kevin J Yarema, Michael J Betenbaugh, Frederick J Krambeck

“…The model further elucidated limitations in the two analytical platforms including a defect in the microarray for detecting the GnTV (MGAT5) enzyme. Our results demonstrate the potential of systems glycobiology tools for elucidating key glycan biomarkers and potential therapeutic targets. …”
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Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada. by Jocelyn Bernier-Lachance, Julie Arsenault, Valentine Usongo, Éric Parent, Josée Labrie, Mario Jacques, François Malouin, Marie Archambault

“…A total of 309 chicken drumsticks and thighs were randomly selected in 2013 from 43 retail stores in the Monteregie. …”
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Rapid changes in transcription profiles of the Plasmodium yoelii yir multigene family in clonal populations: lack of epigenetic memory? by Deirdre Cunningham, Jannik Fonager, William Jarra, Celine Carret, Peter Preiser, Jean Langhorne

“…Using microarray and quantitative RT-PCR, we show that despite this very restricted transcription in a single cell, many yir genes are transcribed throughout the intra-erythrocytic asexual cycle. …”
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A retrospective analysis of 6942 amniocentesis cases by Qingsha An, Yuxiao Huang, Feifei Yu, Yilun Tao, Juan Li, Xiaoze Li

“…Among the single-method cases, Chromosomal Microarray Analysis (CMA) was the most frequently selected technique (14.18%). …”
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Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma by Rui Liu, Haiyang Zhang, Yan Zhang, Shuang Li, Xinyi Wang, Xia Wang, Cheng Wang, Bin Liu, Ke Zen, Chen-yu Zhang, Chunni Zhang, Yi Ba

“…In addition, the expression levels of 21,400 genes in tissues and cells were detected by microarray. It was shown that peroxisome proliferator-activated receptor gamma coactivator-1 alpha expression was significantly downregulated in hepatocellular carcinoma compared with normal liver tissues. …”
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Clinical case of distal arthrogryposis in combination with epilepsy due to an unbalanced translocation by T. V. Kozhanova, S. S. Zhilina, T. I. Meshсheryakova, N. P. Prokopyeva, A. G. Prityko, N. N. Zavadenko

“…This clinical observation demonstrates an opportunity of using innovative molecular cytogenetic technologies in the search for disease-related genetic causes in the absence of mutations detected by whole exome sequencing.…”
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Comprehensive computational analysis reveals H5N1 influenza virus-encoded miRNAs and host-specific targets associated with antiviral immune responses and protein binding. by Fatima Noor, Muhammad Hamzah Saleem, Muhammad Rizwan Javed, Jen-Tsung Chen, Usman Ali Ashfaq, Mohammad K Okla, Mostafa A Abdel-Maksoud, Yasmeen A Alwasel, Wahidah H Al-Qahtani, Huda Alshaya, Ghulam Yasin, Sidra Aslam

“…H5N1 virus (H5N1V) is highly contagious among birds and it was first detected in humans in 1997 during a poultry outbreak in Hong Kong. …”
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Development of HuMiChip for functional profiling of human microbiomes. by Qichao Tu, Zhili He, Yan Li, Yanfei Chen, Ye Deng, Lu Lin, Christopher L Hemme, Tong Yuan, Joy D Van Nostrand, Liyou Wu, Xuedong Zhou, Wenyuan Shi, Lanjuan Li, Jian Xu, Jizhong Zhou

“…Additionally, HuMiChip was able to detect gene families at as low as 0.001% relative abundance. …”
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The Correlation Analysis Between m6A Methylation Modification and Ferroptosis Induced by Cigarette Smoke in Human Bronchial Epithelium by Xiaomei Duan, Tingting Hu, Lijuan Xu, Zheng Li, Jing Jing, Dan Xu, Jianbing Ding, Fengsen Li, Min Jiang, Jing Wang

“…The ROS, GSH, MDA, and total iron content were detected by relevant detection kits. The expression levels associated with ferroptosis and m6A methylation modification‐related genes were determined via reverse transcription‐quantitative polymerase chain reaction and western blot. …”
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Efficacy and tolerability of rufinamide in the treatment of epilepsy (experience of the Svt. Luka’s Institute of Child Neurology and Epilepsy) by K. Yu. Mukhin, O. A. Pylaeva, M. Yu. Bobylova, N. V. Freydkova, L. Yu. Glukhova, M. O. Abramov

“…We assume that the early introduction of rufinamide (prior to the detection of drug resistance) might have yielded better results.…”
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The Differential Gene Expression Pattern of Mycobacterium tuberculosis in Response to Capreomycin and PA-824 versus First-Line TB Drugs Reveals Stress- and PE/PPE-Related Drug Targ... by Li M. Fu, Shu C. Tai

“…Six among the 42 genes identified in this study are on the list of the top 100 persistence targets selected by the TB Structural Genomics Consortium. …”
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