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301
Identification of G1-regulated genes in normally cycling human cells.
Published 2008-01-01“…<h4>Methodology and findings</h4>We used a robotic mitotic shake-off apparatus to select cells in late mitosis for genome-wide gene expression studies. …”
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302
Clustering, Pathway Enrichment, and Protein-Protein Interaction Analysis of Gene Expression in Neurodevelopmental Disorders
Published 2018-01-01“…In this study, we have used four samples of microarray neuronal developmental data: control, RV (resveratrol), NGF (nerve growth factor), and RV + NGF. …”
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303
Integrating single-cell RNA sequencing, WGCNA, and machine learning to identify key biomarkers in hepatocellular carcinoma
Published 2025-04-01“…Abstract The microarray and single-cell RNA-sequencing (scRNA-seq) datasets of hepatocellular carcinoma (HCC) were downloaded from the Gene Expression Omnibus (GEO) database. …”
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304
Identification of potential biomarkers for 2022 Mpox virus infection: a transcriptomic network analysis and machine learning approach
Published 2025-01-01“…This study aimed to identify the differentially expressed genes (DEGs) induced by the 2022 MPXV infection through comprehensive bioinformatics analyses of microarray and RNA-Seq datasets from post-infected cell types with different MPXV clades. …”
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305
Decrease in pneumococcal co-colonization following vaccination with the seven-valent pneumococcal conjugate vaccine.
Published 2012-01-01“…Co-colonization, serotype identification, and relative serotype abundance were detected by analysis of DNA of the total bacterial growth of the primary culture plate using the plyNCR-RFLP method and a molecular serotyping microarray-based strategy. …”
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306
Expression of Genes Related to Germ Cell Lineage and Pluripotency in Single Cells and Colonies of Human Adult Germ Stem Cells
Published 2016-01-01“…Genome-wide comparisons with microarray analysis confirmed that different haGSC colonies exhibited gene expression heterogeneity with more or less pluripotency. …”
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307
The significance of long chain non-coding RNA signature genes in the diagnosis and management of sepsis patients, and the development of a prediction model
Published 2024-12-01“…The purpose of this study was to determine the value of Long chain non-coding RNA (LncRNA) RP3_508I15.21, RP11_295G20.2, and LDLRAD4_AS1 in the diagnosis of adult sepsis patients and to develop a Nomogram prediction model.MethodsWe screened adult sepsis microarray datasets GSE57065 and GSE95233 from the GEO database and performed differentially expressed genes (DEGs), weighted gene co-expression network analysis (WGCNA), and machine learning methods to find the genes by random forest (Random Forest), least absolute shrinkage and selection operator (LASSO), and support vector machine (SVM), respectively, with GSE95233 as the training set and GSE57065 as the validation set. …”
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308
Transcriptional Profile of Kidney from Type 2 Diabetic db/db Mice
Published 2017-01-01“…The top 10 hub genes were selected from the constructed PPI network of DEGs, including Ccnb2 and Nr1i2, which remained largely unclear in DN. …”
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309
Identification of Differentially Expressed Genes and Long Noncoding RNAs Associated with Parkinson’s Disease
Published 2019-01-01“…This study aims to determine differentially expressed genes (DEGs) and long noncoding RNAs (lncRNAs) associated with Parkinson’s disease (PD) using a microarray. Methods. We downloaded the microarray data GSE6613 from the Gene Expression Omnibus, which included 105 samples. …”
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310
Transcriptional profiling of nitrogen fixation and the role of NifA in the diazotrophic endophyte Azoarcus sp. strain BH72.
Published 2014-01-01“…For selected genes, differential expression was corroborated by real time RT-PCR studies.…”
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311
Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation.
Published 2012-06-01“…Single-nucleotide polymorphisms (SNPs) selected from a recent meta-analysis of PD genome-wide association studies (GWAS) were successfully genotyped in 50 out of the 53 microarray brains, allowing a targeted expression-SNP (eSNP) analysis for 52 SNPs associated with PD affection at genome-wide significance and the 189 probes from FoxO1 regulated genes. …”
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312
Molecular profiles of tumor contrast enhancement: A radiogenomic analysis in anaplastic gliomas
Published 2018-09-01“…Gene set enrichment analysis (GSEA), significant analysis of microarray, generalized linear models, and Least absolute shrinkage and selection operator algorithm were used to explore radiogenomic and prognostic signatures of AG patients. …”
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313
Identifying a unique chromosomal pattern to predict the gemcitabine response in patients with cholangiocarcinoma
Published 2025-04-01“…To predict the response to GEM, we evaluated chromosomal aberrations using a chromosome microarray, and their association with GEM response by histoculture drug response assay. …”
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314
A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome.
Published 2015-01-01“…Finally, gene set enrichment analysis (GSEA) was used as a feature selection technique for input into a support vector machine (SVM) classifier. …”
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315
Identification of Hub Biomarkers and Immune and Inflammation Pathways Contributing to Kawasaki Disease Progression with RT-qPCR Verification
Published 2023-01-01“…Patients and Methods. Gene microarray data were collected from the Gene Expression Omnibus database. …”
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316
Global gene expression profiling reveals SPINK1 as a potential hepatocellular carcinoma marker.
Published 2013-01-01“…Six genes identified by microarray as highly expressed in HH-HCC were confirmed by RT qPCR. …”
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317
Epidemiology of group B streptococcal infection in pregnant women and diseased infants in mainland China
Published 2019-10-01“…Serotype III was the dominant serotype that was observed in GBS isolates. GBS detection and identification has become more commonplace, due to the availability of polymerase chain reaction and DNA microarray technologies. …”
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318
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.
Published 2007-04-01“…<h4>Methods and findings</h4>A gene expression signature for the EWS/FLI off state was determined with microarray expression profiling of Ewing sarcoma cell lines with EWS/FLI-directed RNA interference. …”
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319
Increased cycling cell numbers and stem cell associated proteins as potential biomarkers for high grade human papillomavirus+ve pre-neoplastic cervical disease.
Published 2014-01-01“…As cancer is increasingly presumed to develop from proliferative, tumour initiating, cancer stem cells (CSCs), and as other oncogenic viruses induce stem cell associated gene expression, we evaluated whether presence of mRNA (detected by qRT-PCR) or proteins (detected by flow cytometry and antibody based proteomic microarray) from stem cell associated genes and/or increased cell proliferation (detected by flow cytometry) could be detected in well-characterised, routinely collected cervical samples from high risk HPV+ve women. …”
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320
Immune Condition of Colorectal Cancer Patients Featured by Serum Chemokines and Gene Expressions of CD4+ Cells in Blood
Published 2018-01-01“…The differences in gene expression profiles of whole blood cells and cell subpopulations between CRC patients and healthy controls were analyzed using DNA microarray. Serum cytokine/chemokine concentrations in CRC patients and healthy controls were measured via multiplex detection immunoassays. …”
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