Discovery of Genomic Targets and Therapeutic Candidates for Liver Cancer Using Single-Cell RNA Sequencing and Molecular Docking by Biplab Biswas, Masahiro Sugimoto, Md. Aminul Hoque

“…This study aims to uncover key genomic features, analyze their functional roles, and propose potential therapeutic drugs identified through molecular docking, utilizing single-cell RNA sequencing (scRNA-seq) data from liver cancer studies. …”
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Differences in Intestinal Microbiota Between White and Common Cranes in the Yellow River Delta During Winter by Xiaodong Gao, Yunpeng Liu, Zhicheng Yao, Yuelong Chen, Lei Li, Shuai Shang

“…Based on the COG database, a preliminary functional prediction of the intestinal microbiota was conducted, and 16 metabolic pathways relating to the COG pathway were obtained. …”
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Standing genetic variation and introgression shape the cryptic radiation of Aquilegia in the mountains of Southwest China by Jun-Chu Peng, Ziwen He, Zhi-Qiang Zhang

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Ethics of Sensor-Based Surveillance of People with Dementia in Clinical Practice by Jacob Lahr, Nicole Schulze, Larissa N. Wüst, Claus Beisbart, Lena C. Bruhin, Marcello Ienca, Tobias Nef, Manuel Trachsel, Stefan Klöppel

“…Sensor-based surveillance technology (SST) is increasingly employed in the care of people with dementia (PwD) in hospitals, nursing homes, and home care. With improved functionality and availability of SST, there will likely be a growing utilization in clinical settings. …”
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Profiling the diversity of the village chicken faecal microbiota using 16S rRNA gene and metagenomic sequencing data to reveal patterns of gut microbiome signatures by Mxolisi Nene, Mxolisi Nene, Nokuthula Winfred Kunene, Rian Pierneef, Rian Pierneef, Rian Pierneef, Khanyisile Hadebe

“…ARGs were identified, with MarA, PmrF, and AcrE detected in KwaZulu-Natal, and cpxA, mdtG, and TolA in Limpopo. …”
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Current status of transcriptome sequencing technology in ruminants by Cui JiaYu, Song Lili, Wang Dawei, Liu ZhiLin, Zhang Xin, Jia Zelin, Zhang Yuhang, Xiong Huisheng, Wang Xueli

“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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Effects of enhanced fermentation with high-yielding strains of Tetramethylpyrazine on flavor quality of Douchiba by Panpan Yang, Qin Wang, Yurou Yang, Anyan Wen, Haiying Zeng, Na Liu, Likang Qin

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Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains by Yuanyuan Li, Xi Xiang, Zhiyuan Ren, Rui Wang, Minghui Xie, Gen Li, Xiaohui Yan, Zhilong Zhao, Zixin Deng, Min Xu, Anwei Hou

“…A total of forty-eight TPSs were identified and categorized through phylogenetic analysis, and five representative TPSs distantly related to known TPSs were selected for functional investigation. Biochemical assays revealed that TAC28_6116 is a sesquiterpene synthase producing thujopsan-2β-ol (<b>1</b>) and thujopsene (<b>2</b>), marking the first report of thujopsan-2β-ol production from a bacterial source. …”
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Assessment of proximate composition, mineral element profile and antioxidant properties of the edible oyster mushroom grown in Bangladesh by Sharmin Sultana, Md Shamsuzzaman, Md. Abdus Satter Miah, Akhter Jahan Kakon, Abdullah Hel Mafi, Anupoma Sen, Md. Nurealam Siddiqui, Debu Kumar Bhattacharjya

“…Our result suggests that these studied oyster mushrooms could be a good source of nutrition and antioxidants, which could be used as functional foods.…”
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Pyruvate formate lyase regulates fermentation metabolism and virulence of Streptococcus suis by Qingying Fan, Haikun Wang, Shuo Yuan, Yingying Quan, Rishun Li, Li Yi, Aiqing Jia, Yuxin Wang, Yang Wang

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Unlocking the potential of circulating small extracellular vesicles in neurodegenerative disease through targeted biomarkers and advancements in biosensing by Saqer Al Abdullah, Ivy Cocklereece, Kristen Dellinger

“…Neurodegenerative diseases (NDDs) gradually affect neurons impacting both their function and structure, and they afflict millions worldwide. …”
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Near-infrared spectroscopy of the cerebellum in motor activation tasks by Yew Long Lo, Gerald Teck Heng Chia, Yan Teng Celeste Chen, Eng King Tan

“…Protocol 1 consisted of 5 optodes (4 sources and 1 detector, 4 recording channels) spaced 3 cm apart and comprising single-tipped LED light sources in conjunction with single-tipped fiber-optic detectors. …”
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New Rotation Periods from the Kepler Bonus Background Light Curves by Zachary R. Claytor, Jamie Tayar

“…However, due to Kepler’s large 4″ pixels, many of its light curves are at high risk of contamination from background sources. The new Kepler Bonus Background light curves are deblended using a point-spread function algorithm, providing light curves of over 400,000 new background sources in addition to over 200,000 reanalyzed Kepler prime targets. …”
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Methodology for the identification of bioactive and marker peptides in the organs of cattle and pigs by D. V. Khvostov, N. L. Vostrikova, I. M. Chernukha

“…This category of these food-products is intended for personal  ized nutrition of various age groups in the population, taking into account fortification of the food with nutraceuticals and with functional and metabolically active ingredients obtained from animal and vegetable source. …”
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Molecular mechanisms of leukemogenesis by D. A. Domninskiy

“…Such targets can be enzymes, proteins with other (non-enzymatic) functions, genomic DNA, mRNA, or, for example, certain lipid components of cell membranes. …”
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The cardiac phospho-proteome during pressure overload in mice by Rhys Wardman, Steve Grein, Jennifer Schwartz, Frank Stein, Joerg Heineke

“…Our analysis highlights significant changes in hypertrophic signalling, metabolic remodelling, contractile function, and the stress response pathways. We present proteomic data from the main cardiac cell types (endothelial cells, fibroblasts and cardiomyocytes) to reveal the cellular localisation of the detected phospho-proteins, offering insights into temporal and site-specific phosphorylation events, facilitating the potential discovery of novel therapeutic targets and biomarkers. …”
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Preliminary Design of a GNSS Interference Mapping CubeSat Mission: JamSail by Luis Cormier, Tasneem Yousif, Samuel Thompson, Angel Arcia Gil, Nishanth Pushparaj, Paul Blunt, Chantal Cappelletti

“…First, a flexible, low-cost GNSS interference detection payload capable of characterising and geolocating the sources of radio interference regarding the E1/L1 and E5a/L5 bands will be demonstrated on a global scale. …”
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THEORY AND PRACTICE OF ASSESSING THE LEVEL OF INSTABILITY OF THE EXTERNAL ENVIRONMENT OF THE ENTERPRISE IN A HYBRID WAR by I. Zapukhliak, A. Shegda, О. Mykytiuk, T. Onysenko, K. Petrenko

“…The article proposes a methodological approach to comprehensive assessment of the level of instability of environmental factors of enterprises, which, unlike others, involves the detection of instability in terms of seven components (socio-demographic, economic, technological, environmental, political, legal, ethical) on four criteria: complexity, interdependence, variability and uncertainty of factors, which makes it possible to determine their sources and nature, and thus form an effective response of the enterprise to change. …”
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On Power-Off Temperature Attacks Potential Against Security Sensors by Maryam Esmaeilian, Vincent Beroulle, David Hély

“…Although numerous security sensors and attack detectors have been proposed in the literature to detect different sources of FIAs, it is crucial to ensure that these mechanisms themselves have not been tampered. …”
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Comprehensive analysis of complete chloroplast genome sequence of Morina L. by Peng-Hui Liu, Qing Yuan, Huan Liu, Le-Le Qin, Yao Wei, Xu-Min Li, Fei Ren, Xiao-Lei Ma, Hai-Rui Liu

“…This study is conducive to the development and utilization of the resources of Morina, and provides a theoretical basis for the further study of this species.…”
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